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| Number | Title | Issue Date |
| 7902157 | Azetidine and azetidone derivatives useful in treating pain and disorders of lipid metabolism Disclosed are compounds of the formula wherein Z1 is —CH2—or —C(O)—, R4 and R5 are carbon chains (and optionally, together can form a C2 bridge), u and v are in... | 03/08/2011 |
| 7901893 | NPC1L1 (NPC3) and methods of identifying ligands thereof The present invention provides human, rat and mouse NPCIL1 polypeptides and polynucleotides encoding the polypeptides. Methods for detecting ligands which bind to NPC1L1 and block intestinal cholesterol absorption are provided. Also included is a method of identifyi... | 03/08/2011 |
| 7704988 | Anti-hypercholesterolemic compounds This invention provides cholesterol absorption inhibitors of Formula I: and the pharmaceutically acceptable salts and esters thereof. The compounds are useful for lowering plasma cholesterol levels, particularly LDL cholest... | 04/27/2010 |
| 7696177 | Anti-hypercholesterolemic compounds This invention provides cholesterol absorption inhibitors of Formula (I), and the pharmaceutically acceptable salts and esters thereof. The compounds are useful for lowering plasma cholesterol levels, particularly LDL cholesterol, and for treating and preventing ath... | 04/13/2010 |
| 7622449 | Anti-hypercholesterolemic compounds This invention provides cholesterol absorption inhibitors of Formula I: and the pharmaceutically acceptable salts and esters thereof. The compounds are useful for lowering plasma cholesterol levels, particularly LDL cholest... | 11/24/2009 |
| 7407772 | Screening and selection methods for statin drug combinations A method for screening statins in their open acid form to determine the susceptibility of each tested statin to metabolic glucuronidation is provided. Also provided is a method for determining if a non-statin pharmaceutical drug co-administered with a statin that is... | 08/05/2008 |
| 7125865 | Therapeutic compounds for treating dyslipidemic conditions The present invention relates to novel LXR ligands of Formula I and the pharmaceutically acceptable salts, esters and tautomers thereof, which are useful in the treatment of dyslipidemic conditions, particularly depressed levels of HDL cholesterol. | 10/24/2006 |
| 6908934 | Therapeutic compounds for treating dyslipidemic conditions Compounds of Formula I and the pharmaceutically acceptable salts and esters thereof, wherein Z is selected from the group consisting of: (a) Formula Ia | 06/21/2005 |
| 5547957 | Method of treating androgenic alopecia with 5-.alpha. reductase inhibitors The instant invention involves a method of treating and/or reversing androgenic alopecia and promoting hair growth, and methods of treating acne vulgaris, seborrhea, and female hirsutism, by administering to a patient in need of such treatment a 5.alpha.-... | 08/20/1996 |
