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Attorney: Precivale; Shelley G.


Number of patents: 35
Last date: December 26, 1995

NumberTitleIssue Date
5478729Immunoassay for homocysteine
This invention pertains to methods to detect a compound in the presence of a homolog that is immunologically related to the analyte. The invention is particularly suited for the detection of homocysteine in the presence of cysteine. The methods of this in...
12/26/1995
5446137Oligonucleotides containing 4'-substituted nucleotides
This invention relates to oligonucleotides having at least one nucleotide that is substituted at the 4' position of the sugar moiety with a substituent other than hydrogen. These oligonucleotides are useful in hybridization assays and as therapeutic agent...
08/29/1995
5256536Nucleotide probe for Neisseria gonrrhoeae
A nucleotide sequence characteristic of Neisseria gonorrhoeae is disclosed. The sequence can be the basis for hybridization type, nucleic acid-based, rapid, in vitro diagnostic assays. The unique nature of the sequence makes it possible to clearly discrim...
10/26/1993
4828108Package having fiber-containing sheath and apparatus and method for packaging
The package of the present invention comprises a sheath formed from a folded, relatively rigid strip having structure for receiving and releasably holding the ends of the fiber to be packaged. In a preferred embodiment, the fiber is between the two folded...
05/09/1989
4828109Package having fiber-containing sheath and apparatus and method for packaging
The package of the present invention comprises a sheath formed from a folded, relatively rigid strip having structure for receiving and releasably holding the ends of the fiber to be packaged. In a preferred embodiment, the fiber is between the two folded...
05/09/1989
4822802Method of fentanly administration for postoperative pain relief
A method of postoperative pain relief using transdermal delivery of fentanyl or its analgetically effective derivatives preceded by a dose of said material to increase the serum drug levels to steady state more quickly....
04/18/1989
4820720Transdermal drug composition with dual permeation enhancers
A dosage form that coadministers a drug and two percutaneous absorption enhancers to a defined area of the skin is described. The dosage form comprises a body that contains supplies of drug and enhancers and has a basal surface that contacts the area of s...
04/11/1989
4816258Transdermal contraceptive formulations
A transdermal delivery system for the administering of ethinyl estradiol and levonorgestrel, in combination, utilizing a polymer matrix having the drug formulation along with a permeation enhancer dispersed throughout....
03/28/1989
4788062Transdermal administration of progesterone, estradiol esters, and mixtures thereof
A transdermal delivery system for the administering of progesterone and an estradiol ester alone or in combination utilizing a polymer matrix having the drug(s) along with a permeation enhancer dispersed throughout....
11/29/1988
4781924Transdermal drug delivery device
A diffusional drug delivery device is described which can provide for stability of the adhesive and system components, elimination of the initial burst of drug and hence irritation, and to provide for delayed onset of therapeutic effect along with deliver...
11/01/1988
4777049Constant release system with pulsed release
An osmotic delivery system is disclosed for delivering a useful agent at a controlled and constant rate modulated by a pulsed delivery of the useful agent to an environment of use....
10/11/1988
4755180Dosage form comprising solubility regulating member
An osmotic dosage form is disclosed comprising a polymeric olefin, vinyl, condensation, addition or silicon film that surrounds a member selected from the group consisting of a buffer and osmogent which member is released by the film as a means for govern...
07/05/1988
4753802Verapamil dosage form
An osmotic dosage form comprising verapamil and mannitol in a nonequilibrium ratio....
06/28/1988
4751071Composition comprising salbutamol
An osmotic delivery system is disclosed for delivering a useful agent at a controlled and constant rate modulated by a pulsed delivery of the useful agent to an environment of use....
06/14/1988
4747847System for delivering potassium chloride with enhanced bioacceptability
A composition of matter comprising a drug, a neutral hydrogel and an ionic hydrogel. The composition can be administered from a delivery system to a biological receptor over time....
05/31/1988
4743247Process for manufacturing dosage form
A device is disclosed with an internal space for receiving a beneficial agent. The device comprises a wall surrounding a compartment provided with an internal space and a hydrogel. A passageway in the wall connects the exterior of the device with the inte...
05/10/1988
4743248Dosage form for delivering acid sensitive beneficial agent
A dosage form is disclosed, which dosage form comprises an outside wall and an inside wall, which inside wall comprises means for changing its structural integrity in response to fluid having a pH greater than 5 that enters the dosage form, thereby changi...
05/10/1988
4741735Intravenous system for delivering a beneficial agent
A formulation chamber is disclosed comprising a wall surrounding a lumen containing a device for delivering a beneficial agent. The chamber has an inlet for admitting a fluid into the chamber and an outlet for letting an agent formulation leave the chambe...
05/03/1988
4741734Releasing means for adding agent using releasing means to IV fluid
A formulation chamber is disclosed comprising a wall surrounding a lumen containing a device for delivering a beneficial agent. The chamber has an inlet for admitting a fluid into the chamber and an outlet for letting an agent formulation leave the chambe...
05/03/1988
4740197Intravenous system for delivering a beneficial agent via polymer delivery
A formulation chamber is disclosed comprising a wall surrounding a lumen containing a device for delivering a beneficial agent. The chamber has an inlet for admitting a fluid into the chamber and an outlet for letting an agent formulation leave the chambe...
04/26/1988
4740198Method of administering intravenous drug using rate-controlled dosage form
A formulation chamber is disclosed comprising a wall surrounding a lumen containing a device for delivering a beneficial agent. The chamber has an inlet for admitting a fluid into the chamber and an outlet for letting an agent formulation leave the chambe...
04/26/1988
4740199Intravenous system for delivering a beneficial agent
A formulation chamber is disclosed comprising a wall surrounding a lumen containing a device for delivering a beneficial agent. The chamber has an inlet for admitting a fluid into the chamber and an outlet for letting an agent formulation leave the chambe...
04/26/1988
4740201Intravenous system for delivering a beneficial agent
A formulation chamber is disclosed comprising a wall surrounding a lumen containing a device for delivering a beneficial agent. The chamber has an inlet for admitting a fluid into the chamber and an outlet for letting an agent formulation leave the chambe...
04/26/1988
4740200Intravenous system for delivering a beneficial agent
A formulation chamber is disclosed comprising a wall surrounding a lumen containing a device for delivering a beneficial agent. The chamber has an inlet for admitting a fluid into the chamber and an outlet for letting an agent formulation leave the chambe...
04/26/1988
4732915Process for increasing solubility of drug
An osmotic system is disclosed for the delivery of haloperidol at a controlled rate over a prolonged period of time....
03/22/1988
4731122Process for manufacturing a thermoplastic molding composition
The invention concerns a process for producing a thermoplastic composition comprising a cellulose ester....
03/15/1988
4729793Composition for manufacturing wall of dispensing device
A dispensing device is disclosed for delivering a beneficial agent. The device comprises (1) a housing defining an internal space, (2) heat responsive means containing a beneficial agent in the space, (3) means for increasing the amount of beneficial agen...
03/08/1988
4728498Process for disinfecting article with device dispensing chlorine donor and chlorine acceptor
This invention concerns a process for disinfecting an article by placing the article in an aqueous environment comprising a device that dispenses a chlorine donor and a chlorine acceptor that generate a chlorine biocide for disinfecting the article....
03/01/1988
4725272Novel bandage for administering beneficial drug
A medical bandage is disclosed comprising a reservoir containing a gelled fluid, rheological agent and a drug. A method of using the bandage for producing a beneficial effect is disclosed also....
02/16/1988
4564663Free radical cure of the bismaleimide of dimer diamine
Free radical cure of the bismaleimide of dimer diamine is accomplished with ydroperoxides promoted with a vanadium trineodecanoate/N,N-dimethyl-p-toluidine mixture to form a hard polymer....
01/14/1986
4562580Photolytic improvement of dye laser lifetimes
The effective lasing lifetime of coumarin 102 in 50:50 ethylene glycol is gnificantly extended by increasing the rate of pumping and photolysis, with a flashlamp in a laser system having a pyrex ultraviolet filter and an inert cover gas....
12/31/1985
4555455Ambient temperature thermal battery
An ambient temperature thermal battery having two relatively high temperature melting electrolytes which form a low melting temperature electrolyte upon activation....
11/26/1985
4540315Method for exploratory trench wall stabilization
Minor slides in a geologic exploratory trench are stabilized by applying a ater diluted vinyl acetate-ethylene copolymer emulsion to the trench walls. Although the resulting emulsion and sand crust provides no structural support, it provides a surface cohe...
09/10/1985
4531013Preparation of a diaminotetranitronaphthalene
A new compound 2,6-diamino-1,4,5,8-tetranitronaphthalene is disclosed and a method of preparation thereof. The new compound is useful as a high energy, high density explosive....
07/23/1985
4529801Primary explosive
A primary explosive, potassium 7-hydroxyamino-4,6-dinitro-4,7-dihydrobenzroxanide ##STR1## is prepared by reacting 4,6-dinitrobenzofuroxan with hydroxylamine in a methanolic solution of potassium bicarbonate....
07/16/1985
 
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