Did You Know...
...that the video game, Pong, was invented by a guy who graduated at the bottom of his engineering class? Nolan Bushnell spent more time running the games at a local amusement park than he did on his studies at the University of Utah. His dreams of working for Disney's amusement empire were dashed when the company wouldn't hire him. Taking a boring job, Nolan daydreamed about electronic versions of popular games. He invented Pong, the first video game, and went on to found Atari Co.
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| Number | Title | Issue Date |
| 7824373 | Self-contained power-assisted syringe A self-contained and hand-held power-assisted syringe is provided which is suitable for the controlled injection of fluid material during medical procedures such as coronary angiography procedures which utilize small-bore and small sized guide catheter systems. The ... | 11/02/2010 |
| 7476810 | Reinforcement of superconducting coils by high-strength materials A reinforced superconducting coil and method for the reinforcement of such coil utilizing composite superconducting wires clad with high-strength material are disclosed. ... | 01/13/2009 |
| 7275301 | Method for reinforcing superconducting coils with high-strength materials A method for manufacturing clad superconducting wire for use in superconducting coils, such wire having improved resistance to electromagnetic forces by using composite superconducting wires that are clad with selected high-stiffness high-strength materials. ... | 10/02/2007 |
| 7262270 | Fusion protein construct and method for inducing HIV-specific serum IgG and secretory IgA antibodies in-vivo The present invention provides a fusion protein construct (gp41HA) consisting of the ectodomain of the HIV-1IIIB envelope glycoprotein gp41 fused to a fragment of the influenza virus HA2 hemagglutinin protein. Immunization in-vivo via an intraperitoneal p... | 08/28/2007 |
| 7169604 | Method for PR-39 peptide mediated selective inhibition of IκBα degradation The present invention provides both a method and means for regulating IκBα degradation, NFκB activity, and NFκB-dependent gene expression within living cells, tissues, and organs in-situ. The selective regulation is performed using native PR-39 peptide or one of... | 01/30/2007 |
| 7112789 | High aspect ratio, high mass resolution analyzer magnet and system for ribbon ion beams The present invention provides a windowframe magnet having an aligned array of paired bedstead coils in mirror symmetry can bend a high aspect ratio ribbon ion beam through angle of not less than about 45 degrees and not more than about 110 degrees, and can focus it... | 09/26/2006 |
| 7105839 | Method and fine-control collimator for accurate collimation and precise parallel alignment of scanned ion beams In system for implanting workpieces with an accurately parallel scanned ion beam, a fine-control collimator construct is used to reduce the deviation of the scanned ion beam from a specified axis of parallelism and thereby improve its collimation. The shape of the f... | 09/12/2006 |
| 7078713 | Electromagnetic regulator assembly for adjusting and controlling the current uniformity of continuous ion beams An electromagnetic regulator assembly for the production of contiguous magnetic fields which are applied to a continuous ion beam is described. The assembly is structured for controlling the uniformity of traveling continuous ribbon-shaped beams; and allows for dire... | 07/18/2006 |
| 7057192 | Radial scan arm and collimator for serial processing of semiconductor wafers with ribbon beams Semiconductor wafers are sequentially mounted on a holder at one end of an arm which is pivoted about its other end. Each wafer is thereby passed on an arcuate path through a parallel-scanned or continuous ribbon-shaped beam for processing. The pivot axis is paralle... | 06/06/2006 |
| 7029668 | Stimulation of angiogenesis via enhanced endothelial expression of syndecan-4 core proteins The present invention provides tangible means and methods for stimulation of angiogenesis via enhanced endothelial expression of core proteins having a syndecan-4 cytoplasmic region intracellularly. The tangible means include a prepared DNA sequence fragment having ... | 04/18/2006 |
| 6852515 | Stimulation of angiogenesis via enhanced endothelial expression of syndecan-4 core The present invention provides tangible means and methods for stimulation of angiogenesis via enhanced endothelial expression of core proteins having a syndecan-4 cytoplasmic region intracellularly. The tangible means include a prepared DNA sequence fragment having ... | 02/08/2005 |
| 6815187 | Stimulation of angiogenesis via syndecan-4 cytoplasmic domain signaling pathway The present invention provides a methodology and compositions for stimulating angiogenesis in-situ within viable cells, tissues and organs comprising endothelial cells. The methodology focuses upon and controls the phosphorylation of the 183rd amino acid residue, se... | 11/09/2004 |
| 6780641 | Immortalized human microglia cell line An immortalized human cell line is provided which has the characteristics of human embryonic microglia. Such immortalized microglia cells express CD68, CD11c and MHC class I and II antigens as surface markers; have demonstrable phagocytic properties; and produce pro... | 08/24/2004 |
| 6761718 | Direction-oriented and spatially controlled bipolar coagulator for in-situ cauterization of adherent cranial tissue occluding a ventricular catheter previously implanted in-vivo The present invention provides a bipolar coagulator which can be passed through the internal lumen of a ventricular catheter previously implanted into a cranial ventricle of a living subject and engaged in-situ. The bipolar coagulator will provide bipolar electrical... | 07/13/2004 |
| 6719781 | Catheter apparatus having an improved shape-memory alloy cuff and inflatable on-demand balloon for creating a bypass graft in-vivo The present invention provides a catheter apparatus, an improved introducer system, and a methodology for creating a bypass on-demand between an unobstructed blood vessel such as the aorta and an obstructed blood vessel such as an obstructed coronary artery in-vivo ... | 04/13/2004 |
| 6669708 | Devices, systems and methods for creating sutureless on-demand vascular anastomoses and hollow organ communication channels The present invention provides devices, systems, assemblies, and methods intended for the introduction and sutureless juncture of a prepared communication channel to the interior spatial volume of a blood vessel or a hollow organ within a living subject. ... | 12/30/2003 |
| 6607720 | Genetically altered mammalian embryonic stem cells, their living progeny, and their therapeutic application for improving cardiac function after myocardial infarction The present invention provides genetically altered mammalian embryonic stem cells, their living descendent progeny having an altered genomic DNA, and therapeutic methods using these cells for improving cardiac function in a living subject after myocardial... | 08/19/2003 |
| 6596276 | Method for inhibiting tumor angiogenesis in a living subject The present invention provides a method for inhibiting tumor angiogenesis in a living subject. The method relies upon tumor angiogenesis mediated by vascular endothelial growth factor and specified induced integrin cell surface receptors expressed on the ... | 07/22/2003 |
| 6592885 | Method for making infection-resistant fabricated textile articles for biomedical applications The present invention provides a method for making an infection-resistant fabricated textile article which is suitable for any in-vivo usage either as a topical bandage, on an implantable configured construct, or as part of a prosthetic mechanical applian... | 07/15/2003 |
| 6534052 | Cardiac function comprising implantation of embryonic stem cell in which differentiation has been initiated The present invention is a method for markedly improving cardiac function and repairing heart tissue in a living mammalian subject after the occurrence of a myocardial infarction. The method is a surgical technique which introduces and implants mammalian ... | 03/18/2003 |
| 6489113 | In-vitro diagnostic methods for determining whether a primary breast tumor is clinically metastatic A system of diagnostic test methods are provided for diagnosing whether a primary breast tumor from an individual human subject is a clinically metastatic tumor. These in-vitro diagnostic methods detect and utilize the presence or absence of a 55 kilodalt... | 12/03/2002 |
| 6316652 | Drug mitochondrial targeting agents The invention relates to novel targeting drug agents that are targeted for entry into the mitochondria. More specifically, the agents are cisplatin derivatives called mitoplatins which are useful as anti-tumor agents. Mitoplatins are named for their targe... | 11/13/2001 |
| 6159702 | In-vitro diagnostic method for determining whether a primary breast tumor is clinically metastatic A system of diagnostic test methods are provided for diagnosing whether a primary breast tumor from an individual human subject is a clinically metastatic tumor. These in-vitro diagnostic methods detect and utilize the presence or absence of a 55 kilodalt... | 12/12/2000 |
| 6099542 | Catheter apparatus and methodology for generating a fistula on-demand between closely associated blood vessels at a prechosen anatomic site in-vivo The present invention provides catheter apparatus and catheterization methodology for generating an arteriovenous fistula or a veno-venous fistula on-demand between closely associated blood vessels and at a chosen anatomic site in-vivo. The catheter appar... | 08/08/2000 |
| 6086881 | Spatially aligned conjugated composition having a thioether bond linkage The present invention is a spatially aligned conjugated composition which comprises at least one chemically modified substance which is immunologically representative of a prechosen infectious agent and provides a chemical constituent for entering into an... | 07/11/2000 |
| 6043342 | PDZK1 protein containing PDZ interaction domains The present invention provides a unique DNA segment and a previously unknown PDZK1 protein as a marker system indicative of cells and tissues in an abnormal cellular state and which are undergoing a progressive loss of cell regulation and control. The iso... | 03/28/2000 |
| 6022541 | Immunological preparation for concurrent specific binding to spatially exposed regions of vascular permeability factor bound in-vivo to a tumor associated blood vessel The present invention provides an immunological preparation comprising not less than two types of conjugate molecules in admixture for concurrent specific binding to a spatially exposed region of vascular permeability factor (VPF) bound in-vivo to a tumor... | 02/08/2000 |
| 6007544 | Catheter apparatus having an improved shape-memory alloy cuff and inflatable on-demand balloon for creating a bypass graft in-vivo The present invention provides a catheter apparatus, an improved introducer system, and a methodology for creating a bypass on-demand between an unobstructed blood vessel such as the aorta and an obstructed blood vessel such as an obstructed coronary arte... | 12/28/1999 |
| 5998216 | Stabilizing formulation for preserving the integrity of proteins present in a body fluid sampled ex-vivo for evaluation as a specimen The present invention provides stabilizing formulations for maintaining and preserving the integrity of proteins and polypeptides present in a body fluid sample obtained ex-vivo and to be evaluated as a test specimen for either clinical, therapeutic, or r... | 12/07/1999 |
| 5958767 | Engraftable human neural stem cells Stable clones of neural stem cells (NSCs) have been isolated from the human fetal telencephalon. In vitro, these self-renewing clones (affirmed by retroviral insertion site) can spontaneously give rise to all 3 fundamental neural cell types (neurons, olig... | 09/28/1999 |
| 5866127 | Vascular permeability factor targeted compounds New compounds that bind specifically to vascular permeability factor (VPF) are used in methods of targeting these compounds, which include effector molecules that are, e.g., toxic, radioactive, or serve as marker labels, for tumor cells and the associated... | 02/02/1999 |
| 5830224 | Catheter apparatus and methodology for generating a fistula on-demand between closely associated blood vessels at a pre-chosen anatomic site in-vivo The present invention provides catheter apparatus and catheterization methodology for generating an arteriovenous fistula or a veno-venous fistula on-demand between closely associated blood vessels and at a chosen anatomic site in-vivo. The catheter appar... | 11/03/1998 |
| 5810884 | Apparatus and method for closing a vascular perforation after percutaneous puncture of a blood vessel in a living subject The present invention provides unique apparatus, systems and methods for an aligned closing and stabilized sealing of a vascular perforation in a chosen blood vessel after percutaneous puncture and completion of a catheterization procedure. The invention ... | 09/22/1998 |
| 5797920 | Catheter apparatus and method using a shape-memory alloy cuff for creating a bypass graft in-vivo The present invention provides a catheter apparatus, an introducer system, and a methodology for creating a bypass on-demand between an unobstructed blood vessel such as the aorta and an obstructed blood vessel such as an obstructed coronary artery in-viv... | 08/25/1998 |
| 5788986 | Veterinary method for clinically modifying the behavior of dogs exhibiting canine affective aggression using R enantiomers, S enantiomers, and racemic mixtures of selective serotonin reuptake inhibitor compounds or their active metabolites A veterinary method for clinically modifying the behavior of a household pet dog exhibiting a recognized type of canine affective aggression behavior is provided. The veterinary behavior modification method administers at least one compound selected from ... | 08/04/1998 |
| 5762960 | Veterinary method for clinically modifying the behavior of dogs exhibiting canine affective aggression using preferential/discriminatory serotonin reuptake inhibitors A veterinary method for clinically modifying the behavior of a household pet dog exhibiting a recognized type of canine affective aggression behavior is provided. The veterinary behavior modification method administers at least one preferential serotonin ... | 06/09/1998 |
| 5744356 | Specific antibodies against an epitope existing within the A/B region of estrogen receptor proteins A unique monoclonal antibody is provided for determining the functional status of human estrogen receptor protein. The monoclonal antibody will specifically bind and react with an epitope present within the transactivation function, A/B domain of the huma... | 04/28/1998 |
| 5653759 | In-vivo method for repairing a ruptured segment of a therapeutic appliance surgically positioned previously within the body of a living human The present invention is an in-vivo methodology for repairing a ruptured or fragmented segment of a pre-existing therapeutic appliance which has been previously surgically positioned or implanted within the body of a living human. The repair methodology p... | 08/05/1997 |
| 5633972 | Superresolution imaging fiber for subwavelength light energy generation and near-field optical microscopy The present invention provides a superresolution imaging fiber for generating a plurality of subwavelength light energy beams concurrently and for near-field viewing. The imaging fiber comprises a unitary fiber optic array of fixed configuration and dimen... | 05/27/1997 |
| 5617872 | Hypersensitive constriction velocity method for diagnosing Alzheimer's disease in a living human The present invention provides a non-invasive method for diagnosing Alzheimer's disease in a living human subject. The diagnostic method employs a non-invasive automated apparatus which can repetitively measure pupil constriction velocity for a pre-chosen... | 04/08/1997 |
