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| Number | Title | Issue Date |
| 5859193 | Synthetic DNA derived recombinant HIV antigens The present invention provides a method of synthesizing genes encoding unique HIV-1 and HIV-2 envelope proteins and their fragments, thereby allowing overexpression of these proteins in E. coli. The HIV envelope proteins and their fragments have been expr... | 01/12/1999 |
| 5830636 | HEV orf-2 monoclonal antibodies and methods for using same Monoclonal antibodies are described which specifically bind to Hepatitis E Virus (HEV), and more particularly to HEV orf-2 antigen. Also provided are hybridoma cell lines which secrete these monoclonal antibodies, methods for using these monoclonal antibo... | 11/03/1998 |
| 5709997 | Nucleic acid detection of hepatitis GB virus Nucleic oligomer probes useful for detection of HGBV in test samples. Also provided are assays which utilize these probes and test kits which contain these oligomer probes.... | 01/20/1998 |
| 5681695 | Method for increasing specificity in competitive immunoassays The invention is an improved immunoassay and method for detection of antibody to hepatitis B core antigen (anti-HBc). The improved assay comprises the addition of a reducing agent to decrease the number of false positive reactions in the assay.... | 10/28/1997 |
| 5669819 | Chemiluminescent phenanthridinium Acridinium sulfonylamides and isomers, such as phenanthridinium sulfonylamides, may be employed in applications including chemiluminmescent immunoassays. Methods for synthesis of these compounds include contacting an amine with a sulfonylhalide to form a ... | 09/23/1997 |
| 5667974 | Method for detecting nucleic acid sequences using competitive amplification The present invention provides a method for quantitatively detecting the amount of a target nucleic acid sequence which may be present in a test sample. A test sample which may contain a target nucleic acid sequence comprising target sequences X and Y is ... | 09/16/1997 |
| 5667966 | Mouse monoclonal antibodies to Hepatitis E virus and methods for using same Monoclonal antibodies are described which specifically bind to Hepatitis E Virus (HEV), and more particularly to HEV orf-3 antigen. Also provided are hybridoma cell lines which secrete these monoclonal antibodies, methods for using these monoclonal antibo... | 09/16/1997 |
| 5595739 | Hepatitis B virus mutants, reagents and methods for detection Mutant Hepatitis B Virus (HBV) nucleic acid sequences useful for a variety of diagnostic and therapeutic applications, kits for using the HBV nucleic acid sequences, HBV immunogenic particles, and a method for producing antibodies to HBV. Also provided ar... | 01/21/1997 |
| 5593825 | Hepatitis B virus mutants, reagents and methods for detection Mutant Hepatitis B Virus (HBV) nucleic acid sequences useful for a variety of diagnostic and therapeutic applications, kits for using the HBV nucleic acid sequences, HBV immunogenic particles, and a method for producing antibodies to HBV. Also provided ar... | 01/14/1997 |
| 5591440 | Hepatitis B Virus mutants, reagents and methods for detection Mutant Hepatitis B Virus (HBV) nucleic acid sequences useful for a variety of diagnostic and therapeutic applications, kits for using the HBV nucleic acid sequences, HBV immunogenic particles, and a method for producing antibodies to HBV. Also provided ar... | 01/07/1997 |
| 5565570 | Chemiluminescent acridinium salts Acridinium sulfonylamides and isomers, such as phenanthridinium sulfonylamides, may be employed in applications including chemiluminmescent immunoassays. Methods for synthesis of these compounds include contacting an amine with a sulfonylhalide to form a ... | 10/15/1996 |
| 5545739 | Chemiluminescent phenanthridinium salts Acridinium sulfonylamides and isomers, such as phenanthridinium sulfonylamides, may be employed in applications including chemiluminmescent immunoassays. Methods for synthesis of these compounds include contacting an amine with a sulfonylhalide to form a ... | 08/13/1996 |
| 5543524 | Chemiluminescent acridinium salts Acridinium sulfonylamides and isomers, such as phenanthridinium sulfonylamides, may be employed in applications including chemiluminmescent immunoassays. Methods for synthesis of these compounds include contacting an amine with a sulfonylhalide to form a ... | 08/06/1996 |
| 5468646 | Chemiluminescent acridinium salts Acridinium sulfonylamides and isomers, such as phenanthridinium sulfonylamides, may be employed in applications including chemiluminmescent immunoassays. Methods for synthesis of these compounds include contacting an amine with a sulfonylhalide to form a ... | 11/21/1995 |
| 5352803 | 5(6)-methyl substituted fluorescein derivatives 5(6)-methyl substituted fluorescein derivatives and a process for producing 5(6)-methyl substituted derivatives. Also provided are methods for these utilizing these derivatives as indicator reagents in assays for analytes, indicator reagents which compris... | 10/04/1994 |
| 5308750 | Monoclonal antibodies to putative HCV E2/NS1 proteins and methods for using same Monoclonal antibodies which specifically bind to Hepatitis C Virus (HCV) E2/NS1 antigen. Also provided are hybridoma cell lines which secrete these monoclonal antibodies, methods for using these monoclonal antibodies, and assay kits for assays which conta... | 05/03/1994 |
| 5254458 | Immunoassays using antigens produced in heterologous organisms This invention relates to improved "sandwich" immunoassays for antibodies in body fluids of the type where antigen specific for the antibody to be detected is disposed on a solid support and binds antibody from the body fluid, from which the antibody boun... | 10/19/1993 |
| 5145790 | Reagents and method for detecting polychlorinated biphenyls Reagents and an immunoassay for detecting the presence or amount of polychlorinated biphenyls in a test sample. The assay is performed by adding a known concentration of a tracer labeled with a detectable moiety and a known concentration of an analyte-spe... | 09/08/1992 |
| 5006309 | Immunoassay device with liquid transfer between wells by washing A disposable device suitable for performing automated solid-state diagnostic assays which employs microparticles to complex an analyte and where the microparticle complex becomes retained and immobilized on a fibrous matrix such that the presence of analy... | 04/09/1991 |
