Did You Know...
...that one person who claimed to be the inventor of the television is Russian emigre Vladimir Zworykin? In 1929 David Sarnoff, founder of RCA, asked Zworykin what it would take to develop TV for commercial use. He said: a year and a half and $100,000. In reality, it took 20 years and $50 million! Before his death in 1982 at the age of 92, Zworykin said of his invention: "The technique is wonderful. It is beyond my expectations. But the programs! I would never let my children even come close to this thing."
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| Number | Title | Issue Date |
| 8119810 | Process for the preparation of a benzimidazole derivative The invention relates to a process for preparing the compound of formula 1, a valuable intermediate product in the synthesis of the pharmaceutical active substance dabigatran etexilate. ... | 02/21/2012 |
| 8101763 | Method for producing scopine esters The invention relates to a novel method for producing scopine esters of the general formula (1), wherein X—, R, R1, R2, R3, R4, R3′, R4′, R6 and R6′ can have the meanings indicated in the claims and in the description. ... | 01/24/2012 |
| 8044046 | Medicaments for the treatment of chronic obstructive pulmonary disease A pharmaceutical composition comprising a compound of formula 1 wherein: n is 1 or 2; R1 is hydrogen, C1-C4-alkyl, halogen, OH, or —O—C1-C4 | 10/25/2011 |
| 8022082 | Method for the administration of an anticholinergic by inhalation An inhalation kit comprising: (a) an inhaler displaying a flow resistance of about 0.01 to 0.1 √{square root over (kPa)} min/L; and (b) an inhalable powder comprising tiotropium in admixture with a physiologically acceptable excipient with an average particle size... | 09/20/2011 |
| 8008495 | Method for preparing tiotropium salts The invention relates to a new process for preparing tiotropium salts of general formula 1 wherein X− may have the meanings given in the claims and in the specification. ... | 08/30/2011 |
| 8001965 | Capsule for taking an active substance which can be inhaled The invention relates to a novel capsule for receiving an active substance to be administered by inhalation, which is preferably intended for use in a powder inhaler operating on the Bernoulli principle. ... | 08/23/2011 |
| 7994188 | Compounds for treating inflammatory diseases The invention relates to the use of (1α.2β,4β.5α.7β)-7-[(hydroxydi-2-thienylacetyl)oxy]-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane salts for preparing a pharmaceutical composition for the prevention and treatment of diseases associated wit... | 08/09/2011 |
| 7968717 | Crystalline anhydrate with anticholinergic efficacy The invention relates to a new crystalline anhydrate of tiotropium bromide, processes for preparing it and its use for preparing a pharmaceutical composition for the treatment of respiratory complaints, particularly for the treatment of COPD (chronic obstructive pul... | 06/28/2011 |
| 7932273 | 3-[(2-{[4-(hexyloxycarbonylaminoiminomethyl) phenylamino]methyl}-1-methyl-1H-benzimidazol-5-carbonyl)pyridin-2-ylamino]propionic acid ethylester methansulfonate and its use as a medicament Ethyl 3-[(2-{[4-(hexyloxycarbonylaminoiminomethyl)phenylamino]methyl}-1-methyl-1H-benzimidazole-5-carbonyl)pyridin-2-ylamino]propionate methanesulfonate in the crystalline modifications I and II and as the hemihydrate and the use thereof as a pharmaceutical composit... | 04/26/2011 |
| 7923455 | Medicaments for the prevention or treatment of heart failure comprising administration of an anticholinergic The present invention relates to a method for the prevention or the treatment of heart failure comprising administration of a therapeutically effective amount of an anticholinergic 1, medicaments for the prevention or treatment of heart failure comprising one or mor... | 04/12/2011 |
| 7880016 | Process for the preparation of the salts of 4-(benzimidazolylmethylamino)-benzamides The invention relates to a process for preparing a salt of an optionally substituted 4-benzimidazol-2-ylmethylamino)-benzamidine, characterised in that (a) an optionally correspondingly substituted diaminobenzene is condensed with 2-[4-(1,2,4-oxadiazol-... | 02/01/2011 |
| 7879871 | Crystalline forms of tiotropium bromide The invention relates to a new crystalline forms of tiotropium bromide, processes for preparing them and their use for preparing a pharmaceutical composition for the treatment of respiratory complaints, particularly for the treatment of COPD (chronic obstructive pul... | 02/01/2011 |
| 7878193 | Capsule for taking an active substance which can be inhaled The invention relates to a novel capsule for receiving an active substance to be administered by inhalation, which is preferably intended for use in a powder inhaler operating on the Bernoulli principle. ... | 02/01/2011 |
| 7866474 | Film container A film container (FIG. 4) comprises two rectangular films (5) joined together at their periphery to form a receiving chamber (6) for a filling (7), particularly a pharmaceutical formulation of an active substance, at least one of said fil... | 01/11/2011 |
| 7851483 | Medicaments comprising steroids and a novel anticholinergic A pharmaceutical composition comprising: (a) a salt of formula 1 wherein: X− is an anion with a single negative charge; and (b) a steroid 2, processe... | 12/14/2010 |
| 7776315 | Pharmaceutical compositions based on anticholinergics and additional active ingredients A pharmaceutical composition comprising an anticholinergic and at least one additional active ingredient selected from among corticosteroids, dopamine agonistes, PDE-IV inhibitors, NK1-antagonists, endothelin antagonists, antihistamines, and EGFR-kinase inhibitors, ... | 08/17/2010 |
| 7763280 | Tiotropium containing powder formulation for inhalation The invention relates to powdered preparations containing tiotropium for inhalation, processes for preparing them as well as their use in preparing a pharmaceutical composition for the treatment of respiratory complaints, particularly for the treatment of COPD (chro... | 07/27/2010 |
| 7745585 | Antibodies to interleukin-like epithelial-mesenchymal transition inducer (ILEI) The functional characterization of ILEI to be a novel cytokine involved in epithelial/mesenchymal transition and the identification of biologically active ILEI provides the basis for generating ILEI inhibitors, in particular anti-ILEI antibodies, that are useful in ... | 06/29/2010 |
| 7736628 | Powdered inhalants based on modified lactose mixtures as excipient The invention relates to a new process for preparing modified lactose mixtures, these lactose mixtures per se and compositions of medicaments for powder inhalation consisting of one or more micronised active substances and the modified lactose according to the inven... | 06/15/2010 |
| 7736627 | HFA suspension formulations containing an anticholinergic The invention relates to propellant gas formulations containing suspensions of the crystalline monohydrate of (1α,2β,4β,5α,7β)-7-[(hydroxydi-2-thienylacetyl)oxy]-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane-bromide. ... | 06/15/2010 |
| 7736626 | HFA supension formulations containing an anticholinergic The invention relates to propellant gas formulations containing suspensions of the crystalline monohydrate of (1α,2β,4β,5α,7β)-7-[(hydroxydi-2-thienylacetyl)oxy]-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane-bromide. ... | 06/15/2010 |
| 7674788 | Substituted pteridines The invention relates to new pteridines which are suitable for treating respiratory or gastrointestinal complaints or diseases, inflammatory diseases of the joints, skin or eyes, diseases of the peripheral or central nervous system and cancers. This invention also r... | 03/09/2010 |
| 7658949 | Surface modification of lactose excipient for use in powders for inhalation The invention relates to a process for the surface-energy passivation of lactose which is intended for use as an excipient in the production of inhalable powders, and the use of such optimised carrier materials in the manufacture of inhalable powders. ... | 02/09/2010 |
| 7652138 | Anticholinergics, processes for preparing them and pharmaceutical composition containing them A compound of formula 1 wherein: A is a group selected from X− is an anion with a single negative charge; R1 and R | 01/26/2010 |
| 7642268 | Crystalline micronisate, process for the manufacture thereof and use thereof for the preparation of a medicament The invention relates to a crystalline micronisate of (1 α,2β,4β,5α,7β)-7-[(hydroxydi-2-thienylacetyl)oxy]-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane-bromide, processes for preparing it and its use for preparing a pharmaceutical compositio... | 01/05/2010 |
| 7621266 | Nozzle-system for a dispenser for fluids consisting of a nozzle and a nozzle-holder and/or screw cap The invention relates to a nozzle system for a delivery device for liquids, which comprises a nozzle and a device which fixes the nozzle in the delivery device. The device has a liquid reservoir from which a liquid is forced through a nozzle under pressure to delive... | 11/24/2009 |
| 7611694 | Aerosol formulation for inhalation comprising an anticholinergic The present invention relates to a propellant-free, aqueous aerosol formulation for anticholinergics of formula 1 wherein X− denotes an anion. ... | 11/03/2009 |
| 7579358 | Aerosol formulation for inhalation comprising an anticholinergic A pharmaceutical composition comprising: (a) an active substance consisting of a compound of formula 1 wherein X− is an anion; ... | 08/25/2009 |
| 7569581 | Anticholinergics which may be used as medicaments as well as processes for preparing them The present invention relates to new anticholinergics of general formula 1 wherein A, X−, and the groups R1, R2, R3, R4, R5, R6 and R7 | 08/04/2009 |
| 6908204 | Flat panel luminaire having embedded light guides A flat panel luminaire includes a light source, which can be remote, an optical light pipe, and a light-emitting panel. The light-emitting panel includes a tapered light-injection zone joined to a light-emitting zone having the embedded irregular tetrahedrally-shape... | 06/21/2005 |
| 7462367 | Anticholinergic powder formulations for inhalation An inhalable powder comprising: (a) an active substance consisting essentially of a compound of formula 1 wherein X− | 12/09/2008 |
| 7459566 | 1,2,4-oxadiazol-5-one-4-(benzimidazolylmethylamino)benzamidine compounds A process for preparing an optionally substituted 4-benzimidazol-2-ylmethylamino)benzamidine, the process comprising: (a) condensing an optionally suitably substituted diaminobenzene with 2-[4-(1,2,4-oxadiazol-5-on-3-yl)phenylamino... | 12/02/2008 |
| 7429601 | Esters of hydroxyl-substituted nitrogen heterocycles, processes for the preparation thereof as well as the use thereof as pharmaceutical compositions The present invention relates to new compounds of general formula 1 wherein X− and the groups A, B, R, R1, R2, R3, R3′, R4, R4′, Rx | 09/30/2008 |
| 7429600 | Fluorenecarboxylic acid esters, process for the manufacture thereof, and use thereof as medicaments Fluorenecarboxylic acid esters of general formula 1 wherein X− and the groups A, R, R1, R2, R3, R3′, R4, and R4′ have the meanings given in ... | 09/30/2008 |
| 7405224 | Xanthenecarboxylates, processes for preparing them, and their use as pharmaceutical compositions Xanthenecarboxylates of formula 1 wherein: A is a group selected from X− is an anion with a single negative charge; R is hydro... | 07/29/2008 |
| RE39820 | Esters of thienyl carboxylic acids and amino alcohols and their quaternization products Compounds of the formula of which, in exemplary compounds, the thienyl group is attached via the 2-position and; (a) A is 3α-(6β, 7β-epoxy)-tropanyl methobromide and R1 is 2-thieny... | 09/04/2007 |
| 7202368 | Process for the preparation of 4-(benzimidazolymethylamino) benzamidines A process for preparing an optionally substituted 4-benzimidazol-2-ylmethylamino)benzamidine, the process comprising: (a) condensing an optionally suitably substituted diaminobenzene with 2-[4-(1,2,4-oxadiazol-5-on-3-yl)phenylamino... | 04/10/2007 |
| 6884884 | Galactomannan compositions and methods for making and using same The present invention relates to a method for depolymerizing galactomannan and derivatives thereof. The present invention relates to compositions comprising galactomannan and derivatives thereof prepared according to the methods of this invention and uses for the co... | 04/26/2005 |
