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| Number | Title | Issue Date |
| 6326511 | Polymeric product Methods are disclosed for preparing partial and complete esters of poly-γ-glutamic acid, and of the cross-linking of such esters by light of predetermined wavelength. The final products of the present invention are useful in local drug delivery in depot ... | 12/04/2001 |
| 5854227 | Therapeutic derivatives of diphosphonates Novel chemotherapeutic agents having utility in treating infectious diseases such as periodontal disease, certain urinary tract infections, infectious urinary tract stones, and bone cancer, are obtained by combining chemically a diphosphonate compound wit... | 12/29/1998 |
| 4845195 | Inhibitor of ribonucleotide reductase The pentapeptide Val Val Asn Asp Leu has been found to be the shortest peptide sequence that inhibits the activity of the ribonucleotide reductase enzyme of herpes simplex virus in vitro thereby inhibiting viral replication. Longer peptides containing the... | 07/04/1989 |
| 4828987 | Avian retrovirus-bovine growth hormone DNA Recombinant DNA molecules in which an avian retroviral long terminal repeat (LTR) has been ligated to the bovine growth hormone gene are described herein. The retroviral LTR was derived from a plasmid clone of a Schmidt Rupin strain of Rous Sarcoma Virus ... | 05/09/1989 |
| 4814432 | Inhibitor of ribonucleotide reductase A series of peptides has been found to inhibit the activity of the ribonucleotide reductase enzyme of herpes simplex virus in vitro thereby inhibiting viral replication.... | 03/21/1989 |
| 4783407 | Growth of hepatitus A virus in vero cells Hepatitus A virus is grown in Vero cells after passage in in vitro cell culture. Virus replication and continued passage in Vero cells requires extended incubation times, up to about four weeks, for early passages and incubation temperatures no higher tha... | 11/08/1988 |
| 4772685 | Immunogenic peptides of human interleukin-1 and the corresponding anti-peptide antibodies Several distinct peptide regions of the secreted form of purified human interleukin-1 species pI 6.8 have been found to exhibit characteristics associated with highly immunogenic protein moieties and are used to produce specific anti-peptide antibodies. T... | 09/20/1988 |
| 4770781 | Purification of human interleukin-1 species Human interleukin-1 (IL-1) charged species (pI 6.8, 6.0, 5.4 and 5.2) are separated and purified by a rapid and efficient two or three stage chromatographic process. Interleukin-1 species present in concentrated culture fluid from stimulated human mononuc... | 09/13/1988 |
| 4742158 | Purification of hepatitis pre-S antigens by polymerized serum albumin affinity binding Recombinant pre-S-HBsAg is purified by a rapid and efficient two step chromatographic process. Yeast cells expressing recobinant pre-S-HBsAg are disrupted, the cell contents are clarified and separated by polymerized human serum albumin affinity chromatog... | 05/03/1988 |
| 4724145 | Eimeria acervulina immunogens High levels of immunity are achieved in chickens inoculated intramuscularly or orally with E. acervulina extract immunogens. These extracts contain at least 20 polypeptides which induce a protective immune response not only against E. acervulina but also ... | 02/09/1988 |
| 4540669 | Herpes simplex type I subunit vaccine A herpes simplex type I subunit vaccine is prepared from infected chick embryo cells by ultra extraction of the virus while the infected cells are still attached to the growth surface.... | 09/10/1985 |
| 4406902 | Dipeptidase inhibitors Novel chemical compounds are provided which selectively inhibit the metabolism of dipeptidase (E.C.3.4.13.11) and therefore are useful in combination with antibacterial products. These chemical compounds are Z-2-(2,2-dimethylcyclo-propanecarboxamido)-ω-p... | 09/27/1983 |
| 4391800 | Immunologically active peptidyl disaccharides and methods of preparation 2-Amino-2-deoxy-ଲ-D-glucopyranosyl-(1-4)-2-amino-2-deoxy-D-glucoses of the general structural formula: ##STR1## wherein R1 is hydrogen, alkyl (1-7C), substituted alkyl (1-7C), phenyl, substituted phenyl, benzyl, or substituted benzyl... | 07/05/1983 |
| 4286059 | Polysaccharide and bacterial fermentation process for its preparation A process for producing a heteropolysaccharide by a bacterial fermentation procedure in which a species of bacteria or a mutant thereof is incubated in a fermentation medium which contains a carbon source, preferably a hydrolyxed starch, a source of magne... | 08/25/1981 |
| 4271225 | Plow protective member A protective member for the plows of an automatic pinspotter bowling machine is formed of an outer layer of a wear-resistant ball-contacting member, an intermediate strengthening member, and an inner layer of cushioning material.... | 06/02/1981 |
| 4258040 | Cephalosporin compounds Novel cephalosporin compounds having a 3'--methyl, a 3-aryl or 3-heterocycle substituent are prepared by total synthesis. The novel cephalosporin compounds are active against gram-negative and gram-positive microorganisms.... | 03/24/1981 |
| 4251064 | Shock absorber A shock absorber having controlled, continuous, adjustable resistance in both directions is obtained by means of a slide piston passing through a fixed collar and through two movable collars and elastic compression means abutting each movable collar.... | 02/17/1981 |
| 4250265 | Method of obtaining an antigenic fraction from Bordetella bronchiseptica A sub-cellular antigenic fraction of Bordetella bronchiseptica protects against the incidence and severity of swine atropic rhinitis.... | 02/10/1981 |
| 4244980 | Flour compositions Yeast-raised dough products containing 0-60% hard flour, 0-100% bleached soft wheat flour, from 0-70% bleached clear flour and, based on total amount of bleached soft wheat flour and bleached clear flour, from 0.20-1.00 part of sodium calcium alginate per... | 01/13/1981 |
| 4235994 | High molecular weight meningococcal group C vaccine and method for preparation thereof A vaccine against Group C meningococcal meningitis consisting of a polysaccharide of which at least 80% by weight has a molecular weight in excess of 1,000,000 daltons is prepared. The polysaccharide was isolated from Group C hexadecyl trimethylammonium b... | 11/25/1980 |
| 4234182 | Liner for deck chute A deck chute for an automatic pinsetter is provided with a lining of low coefficient of friction material.... | 11/18/1980 |
| 4230315 | Positive turret indexing apparatus Pin contacting means deflect a bowling pin as it exits the cross conveyor belt so that it contacts the turret indexing paddle rather than the wires of the turret baskets.... | 10/28/1980 |
| 4226417 | Carpet belt A carpet belt for an automatic pinspotter machine formed of a soft, flexible, material capable of embedding therein a hard object without being torn.... | 10/07/1980 |
| 4220638 | Antigenic complex from N. Gonorrhoeae An antigenic, immunogenic, non-toxic complex is obtained from the cell surface of N. gonorrhoeae.... | 09/02/1980 |
| 4220313 | Valve operator The present invention provides a valve operator whereby movement of linkage arms connected to a spring loaded movable pressure plate and to a valve stem support opens and closes the valve diaphragm. A manual override clutch assembly disengages the drive m... | 09/02/1980 |
| 4177988 | Pin orientator An automatic bowling machine is provided with means adapted to maintain the distributor belt closer than otherwise to the orientating pan.... | 12/11/1979 |
| 4171810 | Rear filler pad assembly A rear filler pad assembly for an automatic pinspotter bowling machine is formed of two ribbed attaching segments and a grommet receiving segment having elongated serrated slots. Each slot has a wide opening at one end thereof into which a grommet is inse... | 10/23/1979 |
| 4171809 | Respot cell protective bearing member The end of the gripping finger member of a respot cell is provided with a tightly fitted elastomeric wheel-like protective bearing member.... | 10/23/1979 |
| 4169854 | Direct acidified yogurt A direct acidified yogurt is prepared from milk, a thickener blend containing starch, sodium carboxymethyl cellulose, xanthan gum and locust bean gum, and optionally a carbohydrate sweetener. To prepare yogurt, the thickener blend is mixed with milk, the ... | 10/02/1979 |
| 4163807 | Citrus fruit juice and drink Appearance, taste and stability of citrus fruit juices and drinks are improved by incorporating xanthan gum and CMC.... | 08/07/1979 |
| 4151992 | Deck pad for automatic bowling machine An improved deck pad for a pinsetter automatic bowling machine is formed of medium density flexible, resilient, compression resistent cellular material.... | 05/01/1979 |
| 4135979 | Treatment of xanthan gum to improve clarity A xanthan gum fermentation beer containing at least about 1% gum is filtered at a temperature of at least about 112° C. The gum subsequently recovered from the filtrate has improved clarity.... | 01/23/1979 |
| 4118477 | Hepatitis B antigen An improved process for the preparation of hepatitis B antigen by subjecting biological fluid containing heptatitis B surface antigen to isopycanic banding wherein the step gradient is NaBr. Faster and more economical processing is obtained by multiple lo... | 10/03/1978 |
| 4115010 | Automated plate reader Apparatus and method for automatically reading a microtiter plate comprises a light source, a photo sensor, means enabling the photo sensor to measure light transmittance and means for recording and processing the measurements.... | 09/19/1978 |
| 4110223 | Apparatus for recovering embryos from embryonated eggs A method and apparatus for recovering embryos from embryonated eggs wherein the egg is cracked open the shell discarded and the contents dropped onto a continuously vibrating screen which separates the embryo from the yolk sac and accompanying fluid. This... | 08/29/1978 |
| 4105461 | Thickening compositions containing xanthan gum, guar gum and starch A blend of xanthan gum, guar gum, or guar gum derivatives, a starch ether has unique thickening properties. The blend is particularly useful in printing pastes, salad dressings and oil well drilling muds.... | 08/08/1978 |
| 4102996 | Method of preparing hepatitis B core antigen HBc Ag is prepared by isolating Dane particles by isopycnic banding of fluid from HBs Ag positive donors, optionally but preferably pelleting the Dane particles, and then removing the surface antigen by contacting the Dane particles ... | 07/25/1978 |
| 4096035 | Separation of trachoma agent from growth medium impurities Trachoma agent is separated from growth medium impurities by density gradient centrifugation in a sodium bromide solution.... | 06/20/1978 |
| 4084817 | Cushion blocks A cushion block assembly for a cylinder which supports a bowling ball backstop consists of two substantially U-shaped blocks, one block provided with means to lock the cylinder, the other block provided with a hub over which the cylinder is fitted.... | 04/18/1978 |
| 4073743 | Process for preparing an emulsion A process for preparing a highly stable water-in-oil type emulsion consisting of (a) a disperse aqueous phase; (b) a continuous oil phase containing isomannide monooleate emulsifier and a non-hydrated physiologically acceptable fatty acid metal salt. A pa... | 02/14/1978 |
