Park; Keum J. - US Patent Attorneys and Agents

Attorney: Park; Keum J.

Number of patents: 71
Last date: May 01, 2012

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Number	Title	Issue Date
8168213	Medical devices having coating with improved adhesion According to an aspect of the present invention, a medical device is provided which comprises a metallic substrate and polymeric region disposed over and in contact with the metallic substrate. The polymeric region comprises (a) a block copolymer that comprises (i) ...	05/01/2012
8158151	Solvent-assisted loading of therapeutic agents Methods are provided for loading polymeric regions of medical devices with therapeutic agents. In these methods, a polymeric region of a medical device is first pretreated with a solvent system. Subsequently, therapeutic-agent-containing particles are impacted into ...	04/17/2012
8153695	Methods for inhibiting post-surgical adhesions In accordance with one aspect of the invention, a method is provided in which post-surgical adhesions at a surgical site in a patient are inhibited. The method includes topically applying a liquid composition comprising a hydrophobic species, which has a melting poi...	04/10/2012
8152759	Internal medical devices for delivery of therapeutic agent in conjunction with a source of electrical power The invention generally relates to internal (e.g., implantable, insertable, etc.) drug delivery devices which contain the following: (a) one or more sources of one or more therapeutic agents; (b) one or more first electrodes, (c) one or more second electrodes and (d...	04/10/2012
8137338	Tissue patches and related delivery systems and methods Endoluminally delivered tissue patches and related systems and methods for delivering the tissue patches for treating lesions of the alimentary tract are disclosed. A tissue patch includes a substrate, a tissue implant attached to the substrate, and a protective lin...	03/20/2012
8133278	Medical devices having electrodeposited conductive polymer coatings According to one aspect, the present invention provides implantable or insertable medical devices that comprise a substrate and a coating over the substrate that comprises at least one type of conductive polymer and at least one type of additional polymer. ...	03/13/2012
8123728	Antimicrobial agent delivery system An antimicrobial agent delivery system and method are provided for an antimicrobial agent-bearing intervention device. A delivery tube contains the intervention device, where the delivery tube facilitates handling of the intervention device. In one example, the inte...	02/28/2012
8119153	Stents with drug eluting coatings The present invention relates generally to medical devices, preferably a stent, having a drug eluting surface coated or covered with a coating of particles comprising at least an outer layer, an inner layer, and a core comprising a therapeutic agent. Specifically, t...	02/21/2012
8114436	Compositions and methods for delivery of embolics Described herein are compositions comprising one or more embolics attached to an inert, dissolvable matrix as well as kits comprising these novel embolic formulations. Also described are methods of making and using these embolic formulations. ...	02/14/2012
8114148	Medical devices for delivery of therapeutic agent in conjunction with galvanic corrosion According to an aspect of the present invention, at least one ionic therapeutic agent is delivered from an implantable or insertable medical device that comprises an ion-conductive polymeric region that is disposed on a metallic region. The metallic region is in ele...	02/14/2012
8105520	Implantable or insertable medical device resistant to microbial growth and biofilm formation Disclosed are implantable or insertable medical devices that provide resistance to microbial growth on and in the environment of the device and resistance to microbial adhesion and biofilm formation on the device. In particular, the invention discloses implantable o...	01/31/2012
8100819	Electroactive polymer based artificial sphincters and artificial muscle patches Provided are artificial muscle patches, which are adapted to be implanted adjacent a patient's heart, and artificial sphincter cuffs, which are adapted to be implanted around a body lumen, such as the urethra, the anal canal, or the lower esophagus. The devices of t...	01/24/2012
8092821	Medical devices having polymeric regions with improved adhesion According to an aspect of the present invention, implantable or insertable medical devices are provided, which contain at least one polymeric region in contact with a metallic region. The polymeric region contains at least one block copolymer that contains at least ...	01/10/2012
8092818	Medical devices having bioactive surfaces According to an aspect of the present invention, medical devices are provided, which contain (a) a substrate and (b) a polymeric region disposed over the substrate which contains at least one block copolymer. The block copolymer, in turn, contains at least two polym...	01/10/2012
8075906	Medical devices having polymeric regions with copolymers containing hydrocarbon and heteroatom-containing monomeric species According to an aspect of the present invention, implantable or insertable medical devices are provided, which contain one or more polymeric regions. These polymeric regions, in turn, contain one or more polymers, at least one of which is a copolymer that includes t...	12/13/2011
8067026	Drug release regions for medical devices, which include polycyclic-structure-containing polymers According to an aspect of the present invention, implantable or insertable medical devices are provided, which contain polymeric release regions that control the release of one or more therapeutic agents. The polymeric release regions, in turn, contain one or more p...	11/29/2011
8057827	Chemoablation of tissue using biodegradable, solid salt dosage forms Novel methods for the chemical ablation of tissue (e.g. prostatic tissue) are described. These methods include the steps of: (a) providing one or more solid salt dosage forms comprising 50-100% w/w salt; and (b) inserting one or more of such solid salt dosage forms ...	11/15/2011
8048171	Ureteral stents for release of urologically beneficial agents According to one aspect of the invention, ureteral stents are provided that comprise an elongated stent body and a urologically beneficial agent. The elongated stent body comprises a kidney portion adapted to occupy the kidney of a subject upon implantation, a urete...	11/01/2011
8048168	Partially soluble implantable or insertable medical devices An elongate medical device configured for at least partial implantation or insertion into a subject. The medical device has at least one surface that contains one or more depressions, which are at least partially filled with a soluble material. Also described method...	11/01/2011
8043361	Implantable medical devices, and methods of delivering the same A tubular endoprosthesis including a polymeric material is disclosed. The endoprosthesis has a collapsed position that can be reverted to a first expanded position larger than the collapsed position by heating to a first temperature subsequent to insertion of the en...	10/25/2011
8043359	Medical devices having superhydrophobic surfaces According to an aspect of the invention, medical devices are provided, which have at least two superhydrophobic surface regions which engage one another when the medical device is deployed in vivo. ...	10/25/2011
8034874	Medical devices having polymeric regions that contain fluorocarbon-containing block copolymers In one aspect, the present invention provides implantable or insertable medical devices, which contain at least one polymeric region. The polymeric region contains at least one fluorocarbon-containing block copolymer, which, in turn, contains (a) at least one fluoro...	10/11/2011
8034048	Tissue patches and related delivery systems and methods A tissue patch for treatment of a lesion in an alimentary tract of a patient includes a tissue implant having a top surface and a bottom surface. The tissue patch also includes a substrate completely surrounding the tissue implant such that the substrate forms a fir...	10/11/2011
7993390	Implantable or insertable medical device resistant to microbial growth and biofilm formation Disclosed are implantable or insertable medical devices that provide resistance to microbial growth on and in the environment of the device and resistance to microbial adhesion and biofilm formation on the device. In particular, the invention discloses implantable o...	08/09/2011
7988987	Medical devices containing crazed polymeric release regions for drug delivery A medical device that contains (a) at least one polymeric release region that either contains crazing or which is adapted to undergo crazing as a result of stresses (e.g., mechanical, chemical or thermal) that are applied during the implantation or insertion of the ...	08/02/2011
7964209	Orienting polymer domains for controlled drug delivery The present invention provides a method for the formation of a medical device that comprises a therapeutic agent and a release region, which regulates the rate at which the therapeutic agent is released from the medical device. The method comprises providing a precu...	06/21/2011
7963944	Immobilizing objects in the body Stabilizing an object in the body of a patient involves the injection of a lower critical solution temperature (LCST) material or other flowable material into the body of the patient so that the material contacts the object. The LCST material or other flowable mater...	06/21/2011
7947299	Compositions and techniques for localized therapy A therapeutic medical article is provided which comprises a medical article, a precursor compound and an activator compound. The medical article is adapted, upon administration to a patient, to release the precursor compound and the activator compound such that the ...	05/24/2011
7947073	Resorption-controllable medical implants Bioresorbable medical implants are designed to have different resorption rates over time or over the topography of the implants. The resorption of the medical implants are controlled by including layers having differing resorption rates. The layers resorb sequential...	05/24/2011
7947031	Anti-infective central venous catheter with diffusion barrier layer A catheter includes a wall surrounding a lumen. The wall has an inner portion forming an outer surface of the lumen and an outer portion surrounding at least a portion of an outer surface of the inner portion. A first diffusion rate of materials from the lumen throu...	05/24/2011
7947021	Antimicrobially-charged entry port cuff An entry port cuff for providing antimicrobial properties to a medical device having a portion that is insertable into the body of a patient is disclosed. The cuff, which is charged with an antimicrobial agent, is removably attached to the medical device immediately...	05/24/2011
7939094	Multiphase polymeric drug release region A method is provided for modulating the rate of release of a therapeutic agent from a release region, which constitutes at least a portion of an implantable or insertable medical device and which controls the rate at which the therapeutic is released from the medica...	05/10/2011
7931932	Processes for producing polymer coatings through surface polymerization A medical device with a therapeutic agent-releasing polymer coating. The medical device is provided by a method that comprises: (a) attaching at least one reactive species to a medical device surface, which reactive species leads to chain growth polymerization in th...	04/26/2011
7927620	Medical devices having antifouling character According to an aspect of the invention, medical devices are provided which include (a) a substrate and (b) a coating that includes an antifouling copolymer, an adhesive copolymer, or both. Antifouling copolymers for use in conjunction with the present invention con...	04/19/2011
7923509	Drug delivery compositions and medical devices containing block copolymer A composition for delivery of a therapeutic agent is provided. The composition comprises: (a) a biocompatible block copolymer comprising one or more elastomeric blocks and one or more thermoplastic blocks and (b) a therapeutic agent, wherein the block copolymer is l...	04/12/2011
7919137	Medical devices having adherent polymeric layers with depth-dependent properties According to one aspect of the invention, a method of forming a medical device is provided, which includes: (a) contacting a substrate with a solution that contains (i) one or more types of polymers, (ii) a solvent that contains one or more types of solvent species,...	04/05/2011
7919110	Medical device drug release regions containing non-covalently bound polymers According to one aspect, implantable or insertable medical devices are provided, which contain polymeric release regions that release one or more therapeutic agents. The polymeric release regions, in turn, contain the following: (i) a first bonding polymer having a ...	04/05/2011
7914807	Medical devices having improved performance In accordance with various aspects of the invention, implantable and insertable medical devices are provided, which contain one or more polymeric regions. In one aspect, the polymeric regions comprise (a) a block copolymer that comprises a polyaromatic block and a p...	03/29/2011
7914806	Medical devices having improved performance According to an aspect of the present invention, medical devices are provided that contain at least one polymeric region which contains (a) at least one block copolymer that contains at least at least three polymer blocks that differ from one another and (b) at leas...	03/29/2011
7914805	Implantable or insertable medical devices containing radiation-treated polymer for improved delivery of therapeutic agent An implantable or insertable medical device which comprises (a) a therapeutic agent and (b) a polymeric release region comprising a polymer. The polymeric release region is treated with a radiation dose that is effective to substantially increase the cumulative rele...	03/29/2011

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Attorney: Park; Keum J.