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The ice cream cone was invented at the St. Louis Worlds Fair by Ernest Hamwi in 1904. His waffle booth was next to an ice cream vendor who ran short of dishes. Hamwi rolled a waffle to hold ice cream and the cone was born.
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| Number | Title | Issue Date |
| 8129383 | Aminopterin dosage forms and methods for inflammatory disorders There is disclosed dosage forms and methods for treating a patient with an inflammatory disorder with a therapeutically effective amount of aminopterin, or a pharmaceutically acceptable salt thereof, that achieve efficacy without concomitant toxicity. Specifically, ... | 03/06/2012 |
| 7612071 | Compositions and methods employing aminopterin The present invention relates to pharmaceutical compositions containing the antifolate aminopterin, processes for making the compositions, and methods of using them to treat disorders in adult and pediatric patients. Pharmaceutical compositions substantially free of... | 11/03/2009 |
| 7445712 | Asymmetric forward osmosis membranes There is disclosed a membrane formulation having high flux for forward osmosis applications. There is disclosed a forward osmosis filtration membrane having a salt rejection 99+% or greater, and comprising an asymmetric hydrophobic porous backing and cellulosic fibe... | 11/04/2008 |
| 7303674 | Forward osmosis pressurized device and process for generating potable water There is disclosed a process and device for Forward Osmosis (FO) Pressurized Device (FOPD) in general and one hydraulically coupled to a reverse osmosis (RO device for a FOPRO (Forward Osmosis Pressurized Reverse Osmosis). Specifically, there is disclosed a passive ... | 12/04/2007 |
| 7075187 | Coating material over electrodes to support organic synthesis There is disclosed a coating material formulation for layering a plurality of electrodes to provide a substrate for the electrochemical synthesis of organic oligomers. Specifically, there is disclosed a coating layer of from about 0.5 to about 100 microns thick and ... | 07/11/2006 |
| 6902672 | Open-channeled spiral-wound membrane module There is disclosed a spiral-wound membrane module design for various membrane filtration techniques having significantly reduced fluid flow resistance in the feed stream path. Specifically, the inventive spiral-wound membrane module is designed having a corrugated e... | 06/07/2005 |
| 6849184 | Forward osmosis pressurized device and process for generating potable water There is disclosed a process and device for Forward Osmosis (FO) Pressurized Device (FOPD) in general and one hydraulically coupled to a reverse osmosis (RO device for a FOPRO (Forward Osmosis Pressurized Reverse Osmosis). Specifically, there is disclosed a passive ... | 02/01/2005 |
| 6794191 | Process for forming polymer structures containing an oxygen sensor There is disclosed a process for melting a luminescent oxygen sensitive compound into extruded polymer films. Specifically, there is disclosed a process for thermal melting of oxygen-sensitive indicators into common packaging polymers used for commercial packaging o... | 09/21/2004 |
| 6673242 | Open-channeled spiral-wound membrane module There is disclosed a spiral-wound membrane module design for various membrane filtration techniques having significantly reduced fluid flow resistance in the feed stream path. Specifically, the inventive spiral-wound membrane module is designed having a c... | 01/06/2004 |
| 6656361 | Membrane assisted evaporation process and device for brine concentration There is disclosed amembrane assisted evaporation process (MAE) for economically and reliably removing water added to brine. The process comprises using low-grade waste heat and air to evaporate water from diluted salt brines when the water moves across a... | 12/02/2003 |
| 6248787 | Guanylhydrazones and their use to treat inflammatory conditions This invention concerns new methods and compositions that are useful in preventing and ameliorating cachexia, the clinical syndrome of poor nutritional status and bodily wasting associated with cancer and other chronic diseases. More particularly, the inv... | 06/19/2001 |
| 6180676 | Guanylhydrazones and their use to treat inflammatory conditions This invention concerns new methods and compositions that are useful in preventing and ameliorating cachexia, the clinical syndrome of poor nutritional status and bodily wasting associated with cancer and other chronic diseases. More particularly, the inv... | 01/30/2001 |
| 6143728 | Guanylhydrazones useful for treating diseases associated with T cell activation There is disclosed a method for treating diseases and disorders involving T cell activation and HIV-infection, using the p38 mitogen activated protein kinase (MAPK) signaling pathway as a target for intervention. There is further disclosed a use for guany... | 11/07/2000 |
| 6080407 | Diagnostic assays for MIF The present invention relates to compositions and methods for inhibiting the release and/or biological activity of migration inhibitory factor (MIF). In particular, the invention relates to the uses of such compositions and methods for the treatment of va... | 06/27/2000 |
| 6022900 | Guanylhydrazones and their use to treat inflammatory conditions This invention concerns new methods and compositions that are useful in preventing and ameliorating cachexia, the clinical syndrome of poor nutritional status and bodily wasting associated with cancer and other chronic diseases. More particularly, the inv... | 02/08/2000 |
| 6008255 | Guanylhydrazones and their use to treat inflammatory conditions This invention concerns new methods and compositions that are useful in preventing and ameliorating cachexia, the clinical syndrome of poor nutritional status and bodily wasting associated with cancer and other chronic diseases. More particularly, the inv... | 12/28/1999 |
| 5959871 | Programmable analog array circuit There is disclosed a programmable analog or mixed analog/digital circuit. More particularly, this invention provides a circuit architecture that is flexible for a programmable electronic hardware device or for an analog circuit whose input and output sign... | 09/28/1999 |
| 5921248 | Tobacco combination product filter There are disclosed filters for tobacco combustion products that, when employed in conjunction with exposure to tobacco smoke, inhibit the accumulation of AGEs and AGE-like tobacco- and tobacco smoke-derived adducts in individuals exposed to tobacco smoke... | 07/13/1999 |
| 5902732 | Drug screening process measuring changes in cell volume There is disclosed a method for screening drug candidate compounds for anti-epileptic activity, a method for screening drug candidate compounds for activity to prevent or treat symptoms of Alzheimer's disease, and a method for determining cell viability a... | 05/11/1999 |
| 5873718 | Dental apparatus to remove saliva while retracting cheeks, lips and tongue There is disclosed a sterilizeable, disposable or reuseable device comprising a hollow tubular structure configured having a middle protrusion portion having holes drilled therein for tongue retraction and outer wings for mounting cheek retractors, and tw... | 02/23/1999 |
| 5863443 | In-line agricultural water filter with diverter tube and flush valve A filter device used to remove organic and inorganic debris from a liquid stream, such as irrigation water. The device comprises a diverter tube having a plurality of apertures therein to divert a significant portion of the liquids entering the device ont... | 01/26/1999 |
| 5859062 | Guanylhydrazones and their use to treat inflammatory conditions This invention concerns new methods and compositions that are useful in preventing and ameliorating cachexia, the clinical syndrome of poor nutritional status and bodily wasting associated with cancer and other chronic diseases. More particularly, the inv... | 01/12/1999 |
| 5854289 | Guanylhydrazones and their use to treat inflammatory conditions This invention concerns new methods and compositions that are useful in preventing and ameliorating cachexia, the clinical syndrome of poor nutritional status and bodily wasting associated with cancer and other chronic diseases. More particularly, the inv... | 12/29/1998 |
| 5849794 | Guanylhydrazones and their use to treat inflammatory conditions This invention concerns new methods and compositions that are useful in preventing and ameliorating cachexia, the clinical syndrome of poor nutritional status and bodily wasting associated with cancer and other chronic diseases. More particularly, the inv... | 12/15/1998 |
| 5849307 | Vaccine adjuvant There is disclosed an adjuvant composition for potentiating the immunogenicity of an antigen, comprising water or an aqueous solution and hemozoin or ଲ-hematin.... | 12/15/1998 |
| 5849793 | HIV matrix protein tyrosine position 29 pocket binders There is disclosed a structural genus of compounds, defined according to coordinates in three-dimensional space, that binds amino moieties on neighboring lysine residues in a tyrosine residue 29 pocket of the matrix protein component of the HIV preintegra... | 12/15/1998 |
| 5846796 | Blood-borne mesenchymal cells The present invention relates to a population of blood borne mammalian cells that express a unique profile of surface markers that includes certain markers typical of connective tissue fibroblasts, and are referred to herein as "blood-borne mesenchymal ce... | 12/08/1998 |
| 5840305 | Treatment of HIV-Infection by interfering with host cell cyclophilin receptor activity The present invention relates to therapeutic modalities and pharmaceutical compositions for the treatment of HIV-infection using cyclophilin A and its corresponding human cellular binding partner or receptor as a target for intervention. The present inven... | 11/24/1998 |
| 5819922 | Support system for files A system for maintaining files and documents in an accessible manner in a file container such that the files are retained in a vertical orientation. The system comprises a plurality of deformable, resilient upper retention members to engage an upper porti... | 10/13/1998 |
| 5810020 | Process for removing nitrogen-containing anions and tobacco-specific nitrosamines from tobacco products There is disclosed a process for denitrifying tobacco materials and removing barium from tobacco materials, comprising mixing an aqueous-immiscible organic solvent containing a crown ether with an aqueous solution containing soluble components from tobacc... | 09/22/1998 |
| 5808068 | HIV nuclear localization inhibitors There is disclosed a genus of compounds that have anti-HIV infection therapeutic activity and inhibit nuclear localization of the HIV preintegration complex.... | 09/15/1998 |
| 5804446 | Blood-borne mesenchymal cells The present invention relates to a population of blood borne mammalian cells that express a unique profile of surface markers that includes certain markers typical of connective tissue fibroblasts, and are referred to herein as "blood-borne mesenchymal ce... | 09/08/1998 |
| 5789449 | Treatment of symptoms associated with premenstrual disorders There is disclosed a method for treating certain psychiatric symptoms including anger, rejection sensitivity and a lack of mental or physical energy with administration of a nontoxic dose of a serotonin re-uptake blocker. Preferably, the serotonin re-upta... | 08/04/1998 |
| 5780397 | Extreme pressure additive There is disclosed a lubricant additive ingredient that imparts extreme pressure anti-wear properties to lubricant additive compositions. Specifically, there is disclosed a derivative of a vegetable oil triglyceride, a wax ester or a telomerized oil react... | 07/14/1998 |
| 5744501 | Method for treating late luteal phase dysphoric disorder There is disclosed a method for treating Late Luteal Phase Dysphoric Disorder with administration of a nontoxic dose of a serotonin re-uptake blocker. Preferably, the serotonin re-uptake blocker is fluoxetine or norfluoxetine.... | 04/28/1998 |
| 5707599 | Process for purifying tantalum oxide and other metal oxides There is disclosed a process for producing premium grades of metal oxide comprising (1) providing wet or dried hydrous metal oxide containing high levels (e.g., 2%-10% chloride) of halogen contamination, (2) treating the contaminated metal oxide with a ba... | 01/13/1998 |
| 5588959 | Hemodialysis recirculation measuring method There is disclosed a method for rapidly and inexpensively determining the amount of recirculation in a patient undergoing a dialysis treatment comprising measuring temperature of an arterial limb and a venous limb of a dialysis access, decreasing temperat... | 12/31/1996 |
| 5580873 | Enatiomerically pure hydroxylated xanthine compounds to treat proliferative vascular diseases There is disclosed compounds and pharmaceutical compositions that are a resolved R or S (preferably R) enantiomer of an ω-1 alcohol of a straight chain alkyl (C5-8) substituted at the 1-position of 3,7-disubstituted xanthine. The inventive com... | 12/03/1996 |
| 5567704 | R-enatiomerically pure hydroxylated xanthine compounds to treat baldness There is disclosed compounds and pharmaceutical compositions that are a resolved R or S (preferably R) enantiomer of an ω-1 alcohol of a straight chain alkyl (C5-8) substituted at the 1-position of 3,7-disubstituted xanthine. The inventive com... | 10/22/1996 |
| 5567345 | Lower viscosity telomer oil There is disclosed a lower range viscosity telomer oil with an acid number of less than 20 and a viscosity range of from 5000 sus to 12,000 sus at 40° C. The lower range viscosity telomer oil product of claim 1 further comprises no more than 4% polyunsat... | 10/22/1996 |
