Did You Know...
...that several people are credited with the invention of the flush toilet? Most people have heard of Thomas Crapper (1837-1910), the sanitary engineer who invented the valve-and-siphon arrangement that made the modern toilet possible. Another claimant to "the throne" was British inventor Alexander Cumming who patented a toilet in 1775. Then there's a nameless Minoan (a native of ancient Crete) who lived 4,000 years ago who supposedly was ahead of his time and created the first flush toilet!
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| Number | Title | Issue Date |
| 6133409 | Process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and ଲ-unsaturated carboxylic acid and aldehyde compounds This invention is directed to a process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and ,ଲ-unsaturated carboxylic acid and aldehyde compounds and to polymeric hydroxylamine resin compounds useful therefor.... | 10/17/2000 |
| 6127550 | Stereospecific preparation of chiral 1-aryl-and 1-heteroaryl-2-substituted ethyl-2-amines This invention is directed to methods for stereospecifically preparing [(1-optionally substituted aryl)- or (1-optionally substituted heteroaryl)]-2-substituted ethyl-2-amines, having chirality at the 2-position, and to intermediates to the substituted et... | 10/03/2000 |
| 6080767 | Substituted n-[(aminoiminomethyl or aminomethyl)phenyl]propyl amides The compounds according to the invention are substituted N-[(aminoiminomethyl or aminomethyl)phenyl]propyl amides of formula I herein which exhibit useful pharmacological activity and accordingly are incorporated into pharmaceutical compositions and used ... | 06/27/2000 |
| 6074580 | Method for the preparation of pearls and pearls obtained containing an active ingredient with an undefined crystallization point Pearls of an active principle exhibiting an indefinite crystallization point, wherein said pearls exhibit a prolonged, immediate or combination release profiles, are made by melting the active principle and a crystallization excipient to create a molten m... | 06/13/2000 |
| 6048893 | Substituted phenyl compounds with a substituent having A 1,3-benzodioxole ring This invention is directed to compounds of formula I ##STR1## wherein R1 is CN, CH2 CN, CH.dbd.CHCN, CHO, or CH.dbd.CHCO2 H; R2 is aryl lower alkoxy, heteroaryl lower alkoxy, aryl lower alkylthio or heteroa... | 04/11/2000 |
| 5908639 | Inhalation powder containing antistatic agent A powder composition for inhalation comprising at least one microfine drug and a carrier, in which at least a portion of the said carrier comprises an antistatic agent.... | 06/01/1999 |
| 5797391 | Inhaler An inhaler for powdered medicament in capsules has a swirling chamber which can be opened to allow access of a closed capsule into the swirling chamber for operation of capsule-opening means in the swirling chamber. Access to the swirling chamber is gaine... | 08/25/1998 |
| 5767098 | Anti-acne method and composition Compositions for treating acne that contain a peroxide and an antibiotic selected from the lincomycin family are disclosed. In particular, compositions containing benzoyl peroxide and clindamycin are disclosed along with methods of treating acne using the... | 06/16/1998 |
| 5766635 | Process for preparing nanoparticles Nanoparticles are prepared by dissolving a poly(ethylene oxide) and/or poly(propylene oxide) polylactic copolymer in an organic solvent followed by formation of nanoparticles by mixing the solution containing the polymer with an aqueous solution and by pr... | 06/16/1998 |
| 5727546 | Powder inhaler with breath flow regulation valve There is provided a device for the administration of an inhalation medicament, including a body defining a through-going air pathway having a longitudinal axis, an air inlet, an air outlet forming a mouthpiece, means for dispensing medicament into the pat... | 03/17/1998 |
| 5696095 | Pharmaceutical formulations of spiramycin New formulations of spiramycin suitable for oral administration, particularly for children, comprise spiramycin and potassium acesulfame. These formulations mask the bitterness of spiramycin without adversely affecting the bioavailability or stability of ... | 12/09/1997 |
| 5683723 | Nanoparticles based on a polyoxyethelene and polyactic acid block copolymer The invention discloses nanoparticles offering an extended time before capture by the reticulo-endothelial system. Said particles are composed of an ethylene and/or propylene polyoxide polylactic copolymer optionally mixed with a polylactic polymer.... | 11/04/1997 |
| 5670167 | Process for the production of medicament formulations A medicament compact is produced by placing loose powdered medicament in a mould having a longitudinal axis where a mandrel is positioned along the longitudinal axis of the mould compressing the medicament when a force parallel to the longitudinal axis is... | 09/23/1997 |
| 5665384 | Oily capsules of ketoprofen Stable, pharmaceutical ketoprofen salts for oral administration are provided in oily solutions to avoid direct contact of acid forms of ketoprofen with the gastric or duodenal mucus membranes. Sodium, arginine, lysine and/or N-methylglucamine salts of ket... | 09/09/1997 |
| 5522383 | Powder inhaler having capsule holding structure and anti-static walls An inhaler for inhaling pulverulent medicament from within a capsule comprises a chamber (24) within which the capsule is free to rotate while having its longitudinal axis in the median plane of the chamber and thus generally parallel to the front and rea... | 06/04/1996 |
| 5514383 | Process for the preparation of tablets of derivatives of cephalosporanic acid by direct compression The present invention relates to a pharmaceutical form based on cephalosporin. It relates in particularly to a tabletted pharmaceutical form.... | 05/07/1996 |
| 5446028 | Anti-acne method and composition Composition and method for the treatment of acne including a peroxide and an antibiotic selected from the lincomycin family of antibiotics.... | 08/29/1995 |
| 5413782 | Binding pharmaceuticals to ion exchange resins In a method in which an ionizable pharmaceutical material, such as theophylline, having a pharmaceutically-active anionic group is bonded to an anion exchange resin having cationic groups bonded to displacable anionic groups by bringing said material and ... | 05/09/1995 |
| 5364853 | Thioformamide derivatives Thioformamide compounds of formula (I) are disclosed in which R is alkyl, Y is methylene, ethylene or a direct bond, A is optionally substituted phenyl or pyridyl, R1 is hydrogen and R2 is N-alkylsulphonyl-, N-phenylsulphonyl-N'-alky... | 11/15/1994 |
