Comic actor Danny Kaye received patent D166,807 for the co-design of "Blowout Toy or the Like". It's similar to one of those toys that unravels when you blow into at a birthday party except Kaye's has three blowouts going in different directions, not just one.
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| Number | Title | Issue Date |
| 6916663 | Detection method of proteins on polyacrylamide gels using a dye composition as a silver ion sensitizing agent and the dye composition for the same The present invention relates to a method for detecting proteins on polyacrylamide gels, comprising the steps of sensitizing the proteins with a dye composition comprising an acidic organic dye as a silver ion sensitizing agent, and optionally, a basic organic dye a... | 07/12/2005 |
| 6818408 | Monoclonal antibody recognizing phosphatidylinositol-3,4,5-triphosphate A novel monoclonal antibody that specifically recognizes phosphatidylinositol-3,4,5-triphosphate (PIP3) but does not cross-react with structurally similar phospholipid antigens is advantageous for PIP3-specific immunoassay. The gene in the variable regions of the mo... | 11/16/2004 |
| 7153954 | Method for preparation of LNA phosphoramidites The present invention relates to large scale preparation of LNA phosphoramidites using a 2-cyanoethyl-N,N,N′,N′-tetra-substituted phosphoramidite and a nucleophilic activator, e.g. 2-cyanoethyl-N,N,N′,N′-tetraisopropylphosphoramidite and 4,5-dicyanoimidazole... | 12/26/2006 |
| 7001997 | Proteins, their production and use This invention relates to a novel metalloprotease having a proteolytic activity, its partial peptide or a salt either of them, a DNA coding for the protein, a recombinant vector comprising the DNA, a transformant carrying the recombinant vector, a process for produc... | 02/21/2006 |
| 6998484 | Synthesis of purine locked nucleic acid analogues The present invention relates to a new method for the synthesis of purine LNA (Locked Nucleic Acid) analogues which provides a higher overall yield. The method comprising a regioselective 9-N purine glycosylation reaction followed by a one-pot nucleophilic aromatic ... | 02/14/2006 |
| RE38913 | Biocompatible hydrogel A BIOCOMPATIBLE HYDROGEL, is provided for use in the treatment of humans for cosmetic and functional defects (e.g. in mammas, vocal cords, penis, etc. as endoprostheses), in the provision of intratissue storage sites the prolonged-action medicinal preparations, in v... | 12/06/2005 |
| 6946455 | Interstrand crosslinking agents for DNA and compounds therefor Compounds represented by the general formula (I): which two DNA strands can be interstrand-crossliked: A-L-B-X-B-L-A (I) wherein B represents a chemical structure capable of recognizing the nucleotide sequence of DNA; A represents a chemical... | 09/20/2005 |
| 6946210 | Electrochemical polymer electrolyte membrane cell stacks and manufacturing methods thereof An improved electrochemical polymer electrolyte membrane cell stack is provided that includes one or more individual fuel cell cassettes, each fuel cell cassette having at least one membrane electrode assembly, fuel flow field and oxidant flow field. Within each fue... | 09/20/2005 |
| 6930764 | Laser microdissection system A laser micro-dissection system, which is provided with a laser beam, in particular for the processing of biological material located on a carrier, comprises a laser, a microscope with a camera for the production of a microscope image or video image of the biologica... | 08/16/2005 |
| 6914069 | Pharmaceutically active compounds and methods of use The invention provides substituted pyrazole compounds, and methods of treatment and pharmaceutical compositions that utilize or comprise one or more such compounds. Compounds of the invention are useful for the treatment of mammalian infertility. ... | 07/05/2005 |
| 6914159 | Process for preparing sulfamoyl-substituted phenethylamine derivatives The present invention relates to a novel process for preparing sulfamoyl-substituted phenethylamine derivatives, specifically, 5-{2-[2-(2-alkoxy-phenoxy)ethylamino]-propyl}-2-methoxy-benzene sulfonamide of the formula (1). ... | 07/05/2005 |
| 6894068 | Substituted benzimidazoles as non-nucleoside inhibitors of reverse transcriptase The present invention provides compositions and methods for the treatment of HIV infection. In particular, the present invention provides non-nucleoside inhibitors of reverse transcriptase (RT), as well as methods to treat HIV infection using these non-nucleoside in... | 05/17/2005 |
| 6884597 | Method for detecting acetyltransferase and deacetylase activities and method for screening inhibitors or enhancers of these enzymes A method for simply and conveniently detecting acetyltransferase and deacetylase activities of proteins by executing an acetylation reaction of a peptide substrate with an acetyltransferase, or a deacetylation reaction of an acetylated peptide substrate with a deace... | 04/26/2005 |
| 6872698 | Methods for treating neurological injuries and disorders The present invention relates to methods for treatment of nerve cell death (degeneration) and neurodegenerative diseases. Methods of the invention include administering, an effective amount of GDF-1 alone or in combination with neurotrophin-3, to a patient in need o... | 03/29/2005 |
| 6866150 | Containment unit for protecting medical slides during transit A containment unit for protecting fragile objects (e.g., medical slides) during transit is provided, wherein the unit is light weight, yet secure, and such that the objects are securely held in place during transit (e.g., mailing, delivery) to ensure that they are n... | 03/15/2005 |
| 6858650 | Stable salts of novel derivatives of 3,3-diphenylpropylamines The present invention concerns highly pure, crystalline, stable compounds of novel derivatives of 3,3-diphenylpropylamines in the form of their salts, a method for the manufacture and highly pure, stable intermediate products. The method is in particular char... | 02/22/2005 |
| 6858726 | Synthesis of allofuranose The present invention provides a novel strategy for the synthesis of allofuranose using glucofuranose as starting material in a one-pot reaction. The novel finding is that it is possible to carry out the oxidation of 1,2:5,6-di-O-isopropylidene-α-D-glucofuranose wi... | 02/22/2005 |
| 6852880 | Process for preparing prostalglandin derivatives and stereospecific starting material thereof The present invention relates to a process for effectively preparing prostaglandin derivatives and to a stereospecific alkyl halide containing 15S-alcohol group as a starting material. ... | 02/08/2005 |
| 6849724 | Method for transforming plant, the resultant plant and gene thereof A method for achieving the sufficient expression of a gene in a useful higher plant which has been transformed by transferring the above gene encoding a protein having a function carried by another organism so as to impart the function to the plant. Namely, a method... | 02/01/2005 |
| 6841254 | Coated film The present invention relates to a coated film comprising a polyester film having a coat on at least one side thereof, obtained by applying on at least one side of a polyester film a coating solution containing (1) a self-emulsifiable isocyanate having repeating uni... | 01/11/2005 |
| 6838521 | Dispersant composition used for preparing aqueous pigmented ink for ink-jet The present invention relates to a new dispersant composition used for preparing ink for ink-jet, which provides long term fluidity at a fine injection nozzle of ink-jet, shows a stable injection amount, and gives no coagulation of pigment particles when ink for ink... | 01/04/2005 |
| D498167 | Expandable wire bracelet | 11/09/2004 |
| 6809214 | Shortened synthesis of 3,3-diarylpropylamine derivatives The invention relates to a method for producing derivatives of 3,3-diarylpropylamines of general formula (I) and sterically highly pure, stable intermediate products, and to their use for producing pharmaceutical compositions. ... | 10/26/2004 |
| 6806267 | Apoptosis-inducing compounds The present invention relates to pyrrolobenzoxazepines, pyrrolobenzthiazepines and related compounds having the ability to induce apoptosis, to pharmaceutical compositions comprising these compounds and to their use as anti-tumour agents. ... | 10/19/2004 |
| 6797483 | Polypeptide and DNA thereof The present invention relates to novel secretory polypeptides and precursor proteins thereof, which show a high homology to MIA (melanoma inhibitor activity)/CD-RAP (bovine cartilage-derived retinoic acid-sensitive protein); are specifically expressed in the cartila... | 09/28/2004 |
| 6794391 | Derivatives of pyrimido[6.1-a]isoquinolin-4-one The invention provides compounds or salts thereof of the general formula (I): wherein each of R1 and R2 independently represents a C1-6 alkyl or C2-7 acyl group; X represents O... | 09/21/2004 |
| 6787220 | Multilayer heat shrinkable film A heat shrinkable multilayer film including a thermoplastic heat sealable inner layer, an abuse layer of a thermo-plastic polymer blend having a higher average melting point than said inner layer, and a thermoplastic, optically clear outer layer adjacent said abuse ... | 09/07/2004 |
| 6783769 | Transdermal therapeutic system TTS containing tolterodine The invention relates to a transdermal therapeutic system (TTS) for transcutaneously administering tolterodine over a period of several days and to a method for producing the same. The TTS contains a self-adhesive layer-shaped matrix composition which contains a (me... | 08/31/2004 |
| 6779936 | One-sided printing and manufacturing of a möbius strip The invention provides methods for the one sided printing and manufacture of a Möbius strip. The invention includes a method comprising providing an image (30); aligning three substantially identical copies of the image (30) such that a first copy is ... | 08/24/2004 |
| 6776965 | Structures for precisely controlled transport of fluids The present invention relates to devices for efficient transport, transfer and movement of fluids. In particular, the invention provides fluidic micro-structures for controlled transport and movement of liquids in devices for analytical and other purposes. Devices o... | 08/17/2004 |
| 6734291 | Synthesis of [2.2.1]bicyclo nucleosides A synthesis of [2.2.1]bicyclo nucleosides which is shorter and provides higher overall yields proceeds via the key intermediate of the general formula III, wherein R4 and R5 are, for instance, sulfonates and R7 is, for instance, a ha... | 05/11/2004 |
| 6713464 | Derivatives of 3,3-diphenylpropylamines The invention concerns novel derivatives of 3,3-diphenylpropylamines, methods for their preparation, pharmaceutical compositions containing the novel compounds, and the use of the compounds for preparing drugs. More particularly, the invention relates to novel prodr... | 03/30/2004 |
| 6713089 | Quick release pharmaceutical compositions of drug substances The present invention relates to an oral modified release pharmaceutical composition for the administration of a therapeutically and/or prophylactically effective amount of an active substance (a drug substance), to obtain a relatively fast or quick onset of the the... | 03/30/2004 |
| 6713633 | Compounds capable of cleaving double-stranded DNA and method of utilization of the same Novel chemical species capable of simultaneously alkylating double-stranded DNA and cleaving the same; methods for alkylating and cleaving DNA by using these species; and anticancer agents with the use of these compounds. Compounds represented by the following gener... | 03/30/2004 |
| 6709833 | Monoclonal antibody recognizing phosphatidylinositol-3,4-diphosphate A novel monoclonal antibody that specifically recognizes phosphatidylinositol-3,4-biphosphate (PI-3,4-P2) but does not cross-react with structurally similar phospholipid antigens is advantageous for PI-3,4-P2-specific immunoassay. The gene in the variable regions of... | 03/23/2004 |