...that after Walter Hunt patented the safety pin in 1849, he sold the rights to it for $400?
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| Number | Title | Issue Date |
| 8173092 | Regularly arranged nanoparticulate silica and process for producing the same A novel silica which is in the form of ultrafine particles having mesopores and has a regular structure; and a process for producing the silica. The silica is a self-organized nanoparticulate silica characterized in that the average particle diameter is 4 to 30 nm, ... | 05/08/2012 |
| 8163513 | Method for determining the total clotting activity of a blood or plasma sample The invention relates to a method for determining the total clotting activity of a blood or plasma sample, characterized in that a highly specific, reversible thrombin inhibitor is added to a blood or plasma sample in a defined amount, the clotting of the blood or p... | 04/24/2012 |
| 8153769 | Process for producing proteoglycan An efficient low-cost method of proteoglycan recovery from natural resources. There is provided a process for producing proteoglycan, comprising the steps of immersing a biological sample containing proteoglycan in an alkali solution of 0.0025 to 0.1 N and recoverin... | 04/10/2012 |
| 8152914 | Process for applying a metal coating to a non-conductive substrate Described is a new process for applying a metal coating to a non-conductive substrate comprising the steps of (a) contacting the substrate with an activator comprising a noble metal/group IVA metal sol to obtain a treated substrate, (b) contacting said treated subst... | 04/10/2012 |
| 8152084 | Drier for food waste disposal system A drier for a food waste disposal system. A hollow drum has a charge port and a discharge port for food waste. An agitating screw has a rotating thread which is rotatably disposed in an inner space of the drum and agitates and crushes the food waste, and a rotating ... | 04/10/2012 |
| D657309 | Portable power manager enclosure | 04/10/2012 |
| 8146848 | Pulverizer for food waste treatment apparatus The present invention provides a pulverizer of a food waste treatment apparatus. The pulverizer of the present invention includes a main body, a pulverizing screw and an exhaust channel unit. The main body has a hollow space therein. The pulverizing screw includes a... | 04/03/2012 |
| 8124772 | Intermediate products for producing oxazolidinone-quinolone hybrids The present invention describes intermediates (ZP) for a novel and efficient synthesis of compounds in which the pharmacophores of quinolone and oxazolidinone are linked to one another by way of a chemically stable linker. ... | 02/28/2012 |
| 8124292 | Fuel cell stacks and methods The invention provides a fuel cell stack including a layer of encapsulating material disposed about the separator plate, MEA, and reactant manifold, wherein the reactant manifold is bounded at least in part by the encapsulating material. The fuel cell stack also inc... | 02/28/2012 |
| 8114975 | Protein tyrosine kinase substrate LAT and its use in the identification of (ANT) agonists of the kinase The invention generally relates to compositions and methods for identifying and testing tyrosine kinase signaling pathway agonists and antagonists, and more particularly, methods and compositions for screening compounds and identifying compounds that will modulate t... | 02/14/2012 |
| 8110352 | Method of diagnosing and treating cancer using B-catenin splice variants The invention relates to method of diagnosing and treating cancer, in particular β-catenin related cancers. The invention further relates to methods of identifying CTNNB1 related cancer CTNNB1 therapeutics. ... | 02/07/2012 |
| 8101553 | Antibody library An antibody library is prepared by selecting a light chain variable region capable of binding to the variable region of heavy chain to reproduce an active conformation and using the same. Because of being capable of maintaining the diversity of the heavy chain varia... | 01/24/2012 |
| 8100581 | Method of determining the presence of a mineral within a material The invention relates generally to a method of determining the presence of a mineral within a material, such as a rock, a rock fragment, soil, sand or other geological material including: applying pulsed microwave radiation to the material; detecting radiation emitt... | 01/24/2012 |
| 8097276 | Method for coating particle with lipid film A method for coating an object, i.e. a particle, with two sheets of lipid film having a space formed there between. In the method for coating a particle having a positive electrostatic-charging property with two sheets of lipid film, the particle having a positive e... | 01/17/2012 |
| 8075923 | Use of hederagenin 3-O-α-L-rhamnopyranosyl(1→2)-(β-D-glucopyranosyl(1→4)-α-L-arabinopyranoside or an extract from pulsatillae radix containing the same as a therapeutic agent for solid tumors This invention relates to a use of hederagenin 3-O-α-L-rhamnopyranosyl((1→2)-[β-D-glucopyranosyl(1→4)]-α-L-arabinopyranoside or a Pulsatillae radix extract containing the same as a therapeutic agent for solid tumors. Also, this invention relates to a method o... | 12/13/2011 |
| 8070822 | Tool for controlling the mutual angle between the parts of an artificial hip joint A method for controlling the mutual angle between the parts of an artificial hip joint during an operation for insertion of the artificial hip joint, is described. The stem of the femoral hip prosthesis is fastened permanently or removable in the usual manner in the... | 12/06/2011 |
| 8063114 | Inorganic mesoporous material having chiral twisted structure and process for producing the same A chiral inorganic mesoporous material characterized by having a chiral twisted structure and being mesoporous; a process for producing the material; and a method of using the material. The process for inorganic mesoporous material production is a method in which on... | 11/22/2011 |
| 8039586 | Cerebral organic anion transporter and its gene A cerebral organic anion transporter OAT3 which is useful as a protein regulating the uptake/excretion of organic anionic substances in the brain; a nucleic acid having a base sequence encoding the same; and an antibody against the same. The amino acid sequence and ... | 10/18/2011 |
| 8034602 | Method for producing L-arginine using Disclosed herein are a microorganism producing L-arginine and a method of producing L-arginine using the same. The microorganism is a mutant strain of the genus Corynebacterium, Corynebacterium glutamicum CJR0500. The method for L-arginine production comprise... | 10/11/2011 |
| 8013193 | Method for producing alcohol by hydrogenating lactone and carboxylic acid ester in liquid phase Disclosed is a method for producing an alcohol from a lactone or a carboxylic acid ester, which enables to produce an alcohol from a lactone or a carboxylic acid ester under relatively mild conditions with high yield and high catalytic efficiency. This method also e... | 09/06/2011 |
| 8013137 | Modified enteropeptidase protein Disclosed are novel enteropeptidase polypeptides, polynucleotides encoding the polypeptides, nucleotide constructs, vectors, host cells comprising the polynucleotides, and methods for producing the polypeptides and polynucleotides. Such polypeptides are useful as pr... | 09/06/2011 |
| 8008454 | Fusion protein having the enhanced in vivo activity of erythropoietin The present invention relates to a fusion protein in which a carboxy terminal of human erythropoietin (EPO) is fused with a carboxy terminal peptide fragment of β subunit of human chorionic gonadotropin (HCG), to DNA encoding the fusion protein, and to a method for... | 08/30/2011 |
| 8002466 | Irradiation verification device for radiotherapy installations, and method for handling thereof The present invention relates to an irradiation verification apparatus containing living cell material which is fixed in location on cell supports which are arranged between cell support holders. For irradiation verification, the z co-ordinate of the irradiation ver... | 08/23/2011 |
| 7993876 | DNA encoding phospholipases and methods of using same The invention relates to a DNA sequence that encodes a polypeptide with phospholipase activity and was isolated from Aspergillus and sequences derived therefrom, polypeptides with phospholipase activity encoded by these sequences as well as the use of these p... | 08/09/2011 |
| 7964637 | Process for producing optically active theaspirane A simplified production method of stereoisomer of theaspiran having high optical purity has been desired. An alcohol compound having a specific skeleton is enantioselectively esterified with an enzyme, or an ester compound having a specific skeleton is enantioselect... | 06/21/2011 |
| 7964559 | MVL, an antiviral protein from a cyanobacterium The present invention relates, e.g., to an isolated polypeptide from a cyanobacterium, Microcystis viridis, which binds specifically to an oligosaccharide comprising the tetrasaccharide Man-alpha-(1→6)Man-beta (1→4) GlcNAc-beta(1→4)GlcNAc. The polypepti... | 06/21/2011 |
| D640192 | Portable power manager enclosure | 06/21/2011 |
| 7955859 | Fluorescent labeling compound A rare-earth fluorescent complex which forms a fluorescent complex with two or more rare-earth metals such as europium and terbium and can effectively be excited at a wavelength of 340 nm or longer; a fluorescent labeling agent comprising the rare-earth fluorescent ... | 06/07/2011 |
| 7955823 | Microorganism producing glutamic acid in high yield and a process of producing glutamic acid using the same Disclosed herein are mutant strains, KCCM-10784P and KCCM-10785P, which are obtained through gene manipulation of Corynebacterium glutamicum KFCC-11074, and a process of producing L-glutamic acid using the mutant strains. The mutant strains are capable of pro... | 06/07/2011 |
| D636882 | Covering material | 04/26/2011 |
| 7928415 | Device for irradiating tumour tissue in a patient with a particle beam There is proposed a device for the slice-by-slice irradiation of tumour tissue (3) in a patient using a particle beam, having—an accelerator (7) for generating a particle beam (5) with predetermined energy for each slice, —a raster scanning ... | 04/19/2011 |
| 7927814 | Antibody directed against gastrin-releasing peptide precursor and use thereof Disclosed is a novel method for determination of ProGRP which is free from problems such as the dispersion in the values of measurements and operational constraints such as handling of a test sample. A method for the determination of a gastrin-releasing peptide prec... | 04/19/2011 |
| 7911280 | Amplifier stage An amplifier stage for generating an amplified output signal from an input signal, a mobile device comprising an audio amplifier, and an amplification method for generating an amplified output signal from an input signal using an amplifier stage are described. ... | 03/22/2011 |
| D634850 | Covering material | 03/22/2011 |
| 7906769 | Particle accelerator for radiotherapy by means of ion beams The invention relates to a particle accelerator for radiotherapy by means of ion beams (150). The particle accelerator comprises a sixfold synchrotron ring (100) having six rectilinear beam sections (1 to 6) and six curved beam sections (... | 03/15/2011 |
| 7897397 | Cell fusion promoter and utilization of the same The present invention provides a regeneration promoter for regenerating tissue with the use of somatic stem cells. The invention also provides a cell fusion promoter comprising ATP or its metabolite which is safely usable in vivo, a method of producing fused cells i... | 03/01/2011 |
| 7883040 | Drier for food waste disposal system A drier for a food waste disposal system. A hollow drum has a charge port and a discharge port for food waste. An agitating screw has a rotating thread which is rotatably disposed in an inner space of the drum and agitates and crushes the food waste, and a rotating ... | 02/08/2011 |
| 7880466 | Spectrally selective suppression with steady-state free precession A method for fat-suppressed imaging is disclosed. Such a method may include storing a first spectral component of an echo signal formed at TR/2 from a sample, suppressing a second spectral component of the echo signal at TR/2, re-exciting the stored spectral compone... | 02/01/2011 |
| 7880025 | Ruthenium silyl-arene complex , and method for production thereof The present invention is to provide a ruthenium complex having a novel arene moiety, which has improved solubility in various solvents, and a method for production thereof. The present invention relates to a novel ruthenium complex having an arene moiety, whi... | 02/01/2011 |
| 7847107 | Asymmetric reduction method The present invention is to provide a novel method for producing (2S)-2-benzyl-3-(cis-hexahydro-2-isoindolinylcarbonyl)propionic acid which is useful as a therapeutic agent for diabetes. The present invention relates to a method for producing (2S)-2-benzyl-3-(cis-he... | 12/07/2010 |