"What can be more palpably absurd than the prospect held out of locomotives traveling twice as fast as stagecoaches?"
The Quarterly Review ; March edition, 1825
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 7244847 | Benzimidazole compounds The present invention is directed to novel benzimidazoles according to representative structures I and II, and their derivatives that possess antibacterial activity. This invention is also directed to compositions including the benzimidazole derivatives, and methods... | 07/17/2007 |
| 7094469 | Porous or non-porous substrate coated with an immobilized polymeric composition having sulfonyl groups and hydrophilic functional groups and process A porous or non-porous polymeric substrate having its surface modified with an immobilized fluorocarbon such as perfluorocarbon, polymeric composition is provided. The immobilized fluorocarbon is formed from a monomer having formula: [T—SO2Y—SO2 | 08/22/2006 |
| 6970833 | Internet lottery method and system The present invention provides a game system which utilizes Web sites and thus is solely an Internet based patent. The system provides an individual with the ability to win prizes, view companies Web sites, and play games/lotteries such as a monopoly game board. Thi... | 11/29/2005 |
| 6956126 | Preparation of 6-hydroxyequilenins This invention relates to a process for the preparation of 6-hydroxyequilenins, which are useful as estrogenic agents. ... | 10/18/2005 |
| 6953787 | 5HT2C receptor modulators The present invention relates to novel compounds of Formula (I): which act as 5HT2C receptor modulators. These compounds are useful in pharmaceutical compositions whose use includes the treatment of obesity.... | 10/11/2005 |
| 6940411 | Personal carbon monoxide alarm device A personal alarm device for warning an individual of the presence of an unhealthy amount of carbon monoxide in the blood of the individual, comprising a mouthpiece, a carbon monoxide detector, and an alarm device. The mouthpiece is adapted to detect a minimum predet... | 09/06/2005 |
| 6928751 | Megasonic cleaner and dryer system An apparatus includes a rotatable chuck for supporting a substrate and a splash guard. The splash guard surrounds the chuck and surrounds a substrate mounted on the chuck. The splash guard has a portion that deflects fluid being flung off the substrate by centrifuga... | 08/16/2005 |
| 6923192 | Stackable process chambers A substrate processing system has a first substrate cleaner and a second substrate cleaner. The first substrate cleaner comprises a forward portion and a rear portion. The forward portion includes a rotatable substrate support. The rear portion is vertically thicker... | 08/02/2005 |
| 6914074 | Substituted phenyl naphthalenes as estrogenic agents This invention provides estrogen receptor modulators of formula I, having the structure wherein R1, R2, R3, R4, R5, R6, R7, R | 07/05/2005 |
| 6903238 | Substituted indenones as estrogenic agents This invention provides estrogen receptor modulators of formula I, having the structure R1, R2, and R3 are as defined in the specification, or a pharmaceutically acceptable salt thereof... | 06/07/2005 |
| 6902902 | Human G protein-coupled receptors and modulators thereof for the treatment of metabolic-related disorders The present invention relates to methods of identifying whether a candidate compound is a modulator of a G protein-coupled receptor (GPCR). In preferred embodiments, the GPCR is human. In other preferred embodiments, the GPCR is coupled to Gi and lowers the level of... | 06/07/2005 |
| 6903091 | Biphenyl vasopressin agonists A compound of the formulae (I) or (II): wherein: Y is a moiety selected from NR or —(CH2)n; wherein R is hydrogen or (C1-C6 | 06/07/2005 |
| 6887906 | Compositions and methods for the delivery of oligonucleotides via the alimentary canal The present invention relates to compositions and methods which enhance the transport of nucleic acids, especially oligonucleotides at various sites in the alimentary canal of an animal. The methods and compositions enhance the transport of oligonucleotides across t... | 05/03/2005 |
| 6884814 | Phenyl benzisoxazoles as estrogenic agents This invention provides estrogen receptor modulators of formula I, having the structure wherein, R1, R2, and R3 are as defined in the specification, o... | 04/26/2005 |
| 6881558 | Expression system for cloning toxic genes Methods of cloning and/or amplifying toxic genes in bacteria using a vector which amplifies the toxic gene in bacteria and also allows subsequent expression in mammalian systems is provided. A vector having an origin of replication, a first promoter, a polylinker, a... | 04/19/2005 |
| 6858226 | Fusogenic lipids and vesicles Novel lipid compounds are provided that may be termed “pro-cationic” in that they are neutral or negatively charged until they are either brought into contact with cellular membranes or are internalized by cells. The lipids have a hydrophobic tail group and a hy... | 02/22/2005 |
| 6853697 | Hermetically sealable transfer cask An apparatus, transfer cask, system, and method for defueling a nuclear reactor and transferring spent nuclear fuel from a spent nuclear fuel to a storage cask for long terms storage. In one aspect, the invention is an apparatus for use in transferring a canister of... | 02/08/2005 |
| 6849660 | Antimicrobial biaryl compounds Provided are antibacterial compounds having Formula I: In such compositions, X is O or S; Y is CH2; n is 0 or 1. One of R1 and R1′ is —C(O)NR5R5′ | 02/01/2005 |
| 6841349 | Methods for the reduction of stutter in microsatellite amplification The invention provides a method for reducing stutter in the amplification of a microsatellite comprising the steps of providing a sample comprising a microsatellite having a G+C content of 50% or less; contacting the sample with at least one enzyme having nucleic ac... | 01/11/2005 |
| 6835745 | Phenyl substituted thiophenes as estrogenic agents This invention provides estrogen receptor modulators of formula I, having the structure wherein, R1, R2, R3, X, and Y are as defined in the specificat... | 12/28/2004 |
| 6835546 | Drosophila G protein coupled receptors, nucleic acids, and methods related to the same The present invention provides a Drosophila melanogaster GPCR (DmGPCR) polypeptides and polynucleotides which identify and encode such a DmGPCR. In addition, the invention provides expression vectors, host cells and methods for its production. The invention a... | 12/28/2004 |
| 6818636 | B-ring estratrienes This invention provides 3β-hydroxy-5,7,9-estratriene-17-one and a pharmaceutically acceptable salt of its 3-sulfate ester, which is useful as an estrogen. ... | 11/16/2004 |
| 6806054 | Non-endogenous, constitutively activated known G protein-coupled receptors The invention disclosed in this patent document relates to transmembrane receptors, more particularly to a human G protein-coupled receptor for which the endogenous ligand is known (“known GPCRs”), and most particularly to mutated (non-endogenous) versions of th... | 10/19/2004 |
| 6793450 | Below grade cask transfer facility A system and method for transferring a canister of spent nuclear fuel from a transfer cask to a receiving cask. In one aspect, the system comprises a below grade opening adapted for receiving a cask; a platform positioned within the opening, the platform capable of ... | 09/21/2004 |
| 6774248 | Substituted 2-phenyl benzofurans as estrogenic agents This invention provides estrogen receptor modulators of formula I, having the structure wherein R, R′, A, A′, X, Y, and Y are as defined in the specification, or a pharmaceutically acceptable salt thereof.... | 08/10/2004 |
| 6766818 | Chemical concentration control device A system and method for ensuring constant concentration ratios in multi-fluid mixtures used in wafer processing steps. In one aspect the invention is a method for supplying a multi-fluid mixture to a process tank comprising: transporting a first fluid through a firs... | 07/27/2004 |
| 6767877 | Method and system for chemical injection in silicon wafer processing Silicon wafers are treated with chemicals during the manufacture of integrated circuits according to the method of the invnention in the apparatus of the invention which comprises a process tank for cleaning, rinsing, and/or drying silicon wafers; a first chemical s... | 07/27/2004 |
| 6754980 | Megasonic cleaner and dryer An apparatus for drying a generally flat substrate that has been cleaned has a rotatable support for supporting the substrate, a substrate drying assembly, and a controller. The substrate drying assembly includes a substrate drying assembly support arm, an outlet fo... | 06/29/2004 |
| 6753423 | Compositions and methods for enhanced biostability and altered biodistribution of oligonucleotides in mammals The invention is directed to oligonucleotides and oligonucleosides functionalized to include lipophilic moieties and having improved biostability and altered biodistribution in mammals. In one embodiment, such lipophilic oligonucleotide conjugates are used in a meth... | 06/22/2004 |
| 6747014 | Compositions and methods for non-parenteral delivery of oligonucleotides The present invention relates to compositions and methods which enhance the local and systemic uptake and delivery of oligonucleotides and nucleic acids via non-parenteral routes of administration. Pharmaceutical compositions comprising oligonucleotides disclosed he... | 06/08/2004 |
| 6723747 | Substituted 6H-DiBenzo[c,h]chromenes as estrogenic agents This invention provides estrogen receptor modulators of formula I, having the structure wherein R1, R2, R3, R4 R5, R6, and R7 are as def... | 04/20/2004 |
| 6721754 | System and method for database similarity join Disclosed herein are systems and methods for information organization whereby characteristics regarding entities are inferred from the characteristics of similar entities. This is referred to herein as a “fuzzy similarity join” and is exemplified using a chemica... | 04/13/2004 |
| 6718000 | Ventilated vertical overpack An apparatus, system, and method of storing and transferring a canister of spent nuclear fuel. In one aspect, the apparatus is a lid for a ventilated vertical overpack having a chamber for receiving spent nuclear fuel, the lid having ventilation ducts. In one aspect... | 04/06/2004 |
| D487697 | Set of bottles | 03/23/2004 |