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| Number | Title | Issue Date |
| 7838027 | Pantoprazole multiparticulate formulations Pantoprazole sodium multiparticulates are described which avoid sticking to nasogastric and gastronomy tubes. The pantoprazole multiparticulates have a spheroid core of pantoprazole or an enantiomer thereof, or a salt thereof, a surfactant, and a disintegrant; a sub... | 11/23/2010 |
| 7419978 | Phenyl-aniline substituted bicyclic compounds useful as kinase inhibitors Compounds having the formula (I), and pharmaceutically acceptable salts, prodrugs, and solvates thereof, are useful as kinase inhibitors, wherein R, R1, R2, R5, R6a, R6b | 09/02/2008 |
| 7388098 | Dynamic resolution of isomers and resolved isomers Provided is a dynamic resolution method of enriching a desired isomer of an alpha-substituted carboxylic acid relative to an undesired isomer, the method comprising: (a) in a solvent, contacting the alpha-substituted carboxylic acid, wherein the alpha substitution i... | 06/17/2008 |
| 7381730 | 3-arylquinazoline derivatives as selective estrogen receptor beta modulators Novel quinazoline derivatives possessing activity as estrogen receptor beta (ERβ) modulators are provided which have the general formula I wherein X is O or S; A and B ar... | 06/03/2008 |
| 7300639 | Process for removing metals from liquids A process is provided for removing one or more metals from liquids. Also provided is a process for the synthesis of aP2 inhibiting compounds having the formula (I) wherein R1, R2, R3 | 11/27/2007 |
| 7265145 | Substituted piperidines and pyrrolidines as calcium sensing receptor modulators and method Compounds are provided which are antagonists of the calcium sensing receptor, and have the general formula wherein m is 0, 1, 2, 3 or 4; each X is indepe... | 09/04/2007 |
| 7253174 | N-heterocyclic inhibitors of TNF-α expression N-heterocyclic compounds that block cytokine production via inhibition of p38 kinase are disclosed. In one embodiment, compounds of the present invention are represented by Formula (I): Methods of production, pharm... | 08/07/2007 |
| 7253170 | Pyrazole-amine compounds useful as kinase inhibitors The present invention provides pyrazole derived compounds of formula (I) useful for treating p38 kinase-associated conditions, where W, X, R1, R2, R3, R4, R5... | 08/07/2007 |
| 7253167 | Tricyclic-heteroaryl compounds useful as kinase inhibitors The present invention relates to compounds having the formula, wherein, Q is optionally substituted aryl or heteroaryl, R1 is hydrogen or C1-4alkyl, and R2, R3, R4... | 08/07/2007 |
| 7157451 | Heterocyclic dihydropyrimidine compounds Novel heterocyclic dihydropyrimidine compounds useful as inhibitors of potassium channel function (especially inhibitors of the Kv1 subfamily of voltage gated K+ channels, especially inhibitors Kv1.5 which has been linked to the ultr... | 01/02/2007 |
| 7098235 | Triglyceride and triglyceride-like prodrugs of glycogen phosphorylase inhibiting compounds Prodrugs of glycogen phosphorylase inhibiting compounds are provided which are useful in treating diabetes, having the formula I G(—O2CR′)m(—OH)n(—O2C(CH2)pCH3)q | 08/29/2006 |
| 7060720 | Inhibitors of IMPDH enzyme The present invention discloses the identification of the novel inhibitors of IMPDH (inosine-5′-monophosphate dehydrogenase). The compounds and pharmaceutical compositions disclosed herein are useful in treating or preventing IMPDH associated disorders, such as tr... | 06/13/2006 |
| 6995180 | Glycinenitrile-based inhibitors of dipeptidyl peptidase IV and methods A compound of the formula I: wherein R1, R2, R3 and R4 are as defined herein. Further provided are methods of u... | 02/07/2006 |
| 6992102 | Bicyclic modulators of androgen receptor function The invention provides compounds of the formula I wherein the substitutents are as described herein. Further provided are methods of using such compounds for the treatment of nuclear hormone receptor-associated con... | 01/31/2006 |
| 6683056 | O-aryl glucoside SGLT2 inhibitors and method ##STR1## wherein when Y is ##STR2## or heteroaryl; A is --O(CH2)m, S, --NH(CH2)m, or (CH2)n where n is 0-3 and m is 0-2; and R1 to R6 are as defined herein... | 01/27/2004 |
| 5912348 | Method of making arylamino triazolopyridines Method for making 4-arylamino-1-alkyl-1,2,3!triazolo4,5-c!pyridines by base-promoted isomerization of 7-alkylamino-3-aryl-1,2,3!triazolo4,5-b!pyridines.... | 06/15/1999 |
