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Attorney: Nuzzi; Paul


Number of patents: 6
Last date: October 05, 2010

NumberTitleIssue Date
7807365Cleavage of nucleic acids
The invention relates to compositions and methods of generating a signal indicative of the presence of a target nucleic acid in a sample, where the method includes forming a cleavage structure by incubating a sample comprising a target nucleic acid with a probe. The...
10/05/2010
7794935Reverse transcriptase compositions for flap-mediated detection of a target nucleic acid sequence
The invention relates to compositions for generating a signal indicative of the presence of a target nucleic acid in a sample. The compositions include a reverse transcriptase, a nuclease, an upstream primer and downstream probe. ...
09/14/2010
7736854Methods of detection of a target nucleic acid sequence
The present invention is directed to methods of generating a signal indicative of the presence of a target nucleic acid in a sample by forming a cleavage structure comprising duplex and single-stranded nucleic acid by incubating a sample comprising a target nucleic ...
06/15/2010
7678541Methods and compositions for the detection of a nucleic acid using a non-invasive cleavage reaction
The invention provides methods, compositions and kits for generating a signal indicative of the presence of a target nucleic acid sequence in a sample comprising forming a cleavage structure by incubating a sample comprising a target nucleic acid sequence with upstr...
03/16/2010
7655405Compositions and kits for detection of a target nucleic acid
The present invention is directed to kits and compositions for generating a signal indicative of the presence of a target nucleic acid sequence in a sample, comprising a nucleic acid polymerase lacking 5′ to 3′ exonuclease activity and a thermostable FEN nucleas...
02/02/2010
7585632Compositions and methods for the detection of a nucleic acid using a cleavage reaction
The invention relates to compositions and methods for generating a signal indicative of the presence of a target nucleic acid in a sample utilizing a primer-probe duplex. ...
09/08/2009
 
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