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| Number | Title | Issue Date |
| 6509151 | DNA molecule encoding for cellular uptake of Mycobacterium tuberculosis and uses thereof The present invention relates to a DNA molecule conferring on Mycobacterium tuberculosis an ability to enter mammalian cells and to survive within macrophages. The protein encoded by this gene fragment is useful in vaccines to prevent infection by Mycobac... | 01/21/2003 |
| 6093886 | Vacuum-tight continuous cable feedthrough device A vacuum-tight cable feedthrough device includes a metallic first flange that is penetrated by a slot. Passing through the slot is a flat stripline cable that includes a plurality of conductive signal channels encompassed by a dielectric material on whose... | 07/25/2000 |
| 6090747 | Thermosensitive direct image-recording material A direct image-recording material has a layer of a thermosensitive layer formed on a thin substrate. The substrate comprises an organic polymeric material that is substantially transparent and colorless and has a thickness no greater than about 10 μm. Pr... | 07/18/2000 |
| 6080766 | Method for the treatment of fibroproliferative disorders by application of inhibitors of protein hydroxylation The present invention relates to a method of treating a patient with a fibrotic or fibroproliferative disorder and a method of suppressing formation of collagen and collagen-like substances or biosynthesis of procollagen in living systems by administering... | 06/27/2000 |
| 6027889 | Detection of nucleic acid sequence differences using coupled ligase detection and polymerase chain reactions The present invention relates to the detection of nucleic acid sequence differences using coupled ligase detection reaction and polymerase chain reaction. One aspect of the present invention involves use of a ligase detection reaction coupled to a polymer... | 02/22/2000 |
| 6020540 | Gene encoding endochitinase Two chitinases from Trichoderma harzianum P1 (ATCC 74058) show chitin-containing-fungus-inhibiting activity. One is an endochitinase and the other is a chitobiase. Both have molecular weights of 40 kDa and isoelectric points of 3.9. Endochitinases and chi... | 02/01/2000 |
| 6015556 | Cytotoxic drug therapy A compound comprises a target cell-specific portion, such as an antibody specific to tumor cell antigens, and an inactivating portion, such as an enzyme, capable of converting a substance which in its native state is able to inhibit the effect of a cytoto... | 01/18/2000 |
| 5985958 | Light-curing composite material A light-curing composite material is described which is characterized by a content of anaerobic stabilizer and/or stable organic radicals and which has a reduced light sensitivity and an improved vacuum stability and is therefore suitable in particular as... | 11/16/1999 |
| 5977060 | Insect control with a hypersensitive response elicitor The present invention relates to a method of controlling insects on plants. This involves applying a hypersensitive response elicitor polypeptide or protein in a non-infectious form to a plant or plant seed under conditions effective to control insects on... | 11/02/1999 |
| 5971776 | Adjustable spark plug boot An adjustable spark plug boot in accordance with the present invention includes an assembly, a first groove, a first terminal locator chamber, and a second terminal locator chamber. The assembly has first and second ends with a bore extending from the fir... | 10/26/1999 |
| 5969031 | Methods for preparing polymer blends The present invention relates to a method for preparing polymer composites. The method includes providing a mixture of concentrated emulsions and polymerizing the mixture of concentrated emulsions under conditions effective to form a polymer composite. Th... | 10/19/1999 |
| 5968856 | Sinterable lithium disilicate glass ceramic High-strength sinterable lithium disilicate glass ceramics are described which can be further processed in particular by pressing in the viscous state to shaped dental products.... | 10/19/1999 |
| 5968564 | Injection molding apparatus A molded container top 140 has engravings 145 formed by an embossing 108. The core 120 withdrawn from the cavity 102 and a retaining ring 110 holds the hot molded part 140 in the cavity 102. The molded part 140 shrinks away from the cavity 102 and is push... | 10/19/1999 |
| 5965585 | Method for the treatment of fibroproliferative disorders by application of inhibitors of protein hydroxylation The present invention relates to a method of treating a patient with a fibrotic or fibroproliferative disorder and a method of suppressing formation of collagen and collagen-like substances or biosynthesis of procollagen in living systems by administering... | 10/12/1999 |
| 5965567 | Method for treating nicotine addiction The present invention relates to methods for treating nicotine addiction. The method involves administering to the patient an effective amount of a compound having the formula: ##STR1## wherein R1 is selected from the group consisting of h... | 10/12/1999 |
| 5958791 | Interdigitated electrode arrays for liposome-enhanced immunoassay and test device A test device for detecting or determining an analyte in a test solution includes an absorbent material having contact, liposome lysing and electrochemical measurement portions. The contact portion is positioned for contact with and uptake of the test sol... | 09/28/1999 |
| 5945581 | Implanting disease resistance to plants with viral replicase DNA molecules which do not have a read-through portion The present invention describes a method for the induction of resistance in a plant host to a RNA or DNA virus pathogenic to the plant which comprises isolating a fragment of viral RNA or DNA associated with the replicase portion of the virus genome, spec... | 08/31/1999 |
| 5942421 | System useful for the production of proteins from recombinant DNA in single celled organisms A single celled organism, vector, and method are provided for continuous production of excreted proteins in the absence of substantial host cell replication and without the necessity for the addition of antibiotics to control cell replication. The vector ... | 08/24/1999 |
| 5942559 | Dental light-curing opaquer A dental light-curing opaquer is described which is characterized by a content of cross-linked bead polymerizate with incorporated colored pigment and of polymerizable polyfunctional monomer and which is highly suitable for covering metallic surfaces of d... | 08/24/1999 |
| 5939275 | Mesangial cell lines as models for the study and treatment of diabetic tissue complications An isolated and stable clone of mesangial cells which exhibit characteristics of diabetic cells when grown in normal glucose medium. The cells demonstrate an increase in glucose transport over normal mesangial cells and that provides a model for simulatin... | 08/17/1999 |
| 5938688 | Deep brain stimulation method The present subject matter is directed to a method for treating a conscious. The method includes selecting a conscious patient having impaired cognitive function and applying electrical stimulation to at least a portion of the patient's intralaminar nucle... | 08/17/1999 |
| 5936006 | Filled and polymerizable dental material A filled and polymerizable dental material is described which contains a sol of SiO2 particles in a liquid, organic dispersion agent, the SiO2 particles being organically surface modified, having an average size of 10 to 100 nm and b... | 08/10/1999 |
| 5935339 | Decontamination device and method thereof One embodiment of a decontamination device for a surface, such as a probe, and method thereof in accordance with the present invention includes a first electrode, a second electrode, and a transformer. The first electrode comprises a housing with an openi... | 08/10/1999 |
| 5935885 | Manufacture of ceramic tiles from fly ash The present invention relates to a process for forming glass-ceramic tiles. Fly ash containing organic material, metal contaminants, and glass forming materials is oxidized under conditions effective to combust the organic material and partially oxidize t... | 08/10/1999 |
| 5928931 | Isolation, purification and cloning of retinol dehydratase The present invention relates to retinol dehydratase, the enzyme which synthesizes the retro-retinoid anhydroretinol in the Spodoptera frugiperda insect cell line Sf-21, as well as the DNA molecule encoding that enzyme. The DNA molecule can be incorporate... | 07/27/1999 |
| 5927943 | Inlet casing for a turbine A turbine with the improved inlet casing in accordance with the present invention includes a shaft which extends along and rotates about a central axis. The turbine also includes at least one rotor wheel which is mounted on and extends radially outward fr... | 07/27/1999 |
| 5930546 | Method for making a sinusoidal test object A method for forming a test object containing a sinusoidal pattern corresponding to a specified exposure distribution function comprises: providing an exposed and processed intermediate photographic film containing a distorted sinusoidal pattern image hav... | 07/27/1999 |
| 5925180 | ZrO2 -containing glass-ceramic A ZrO2 -containing glass ceramic is described, the main crystalline phase of which is formed by ZrO2 and which has at least one further crystalline phase, and which can be used in particular in dentistry.... | 07/20/1999 |
| 5918562 | Boat with dual skis A boat in accordance with the present invention includes boat hull and a pair of elongated members or skis or a modification to a standard boat hull to add on a dual ski attachment to make it a dual ski boat. The hull has a port side, a starboard side, an... | 07/06/1999 |
| 5920415 | Transmission of optical signals A system, method and apparatus for transmission of optical signal in which two laser beams, operating at different frequencies, travel nearly loss-free and shape-invariant within an absorbing medium whereby the nonlinearity of the beams cause an adiabatic... | 07/06/1999 |
| 5912257 | Two-photon upconverting dyes and applications Styryl dyes and compositions which exhibit superior two-photon absorption cross-sections and are useful in two-photon pumped cavity lasing, two-photon pumped upconversion lasing, optical power limiting, optical power stabilization, optical signal reshapin... | 06/15/1999 |
| 5912514 | Uninterruptible power supply unit An uninterruptible power supply unit for coupling between an adapter with an adapter connector and an electronic device in accordance with one embodiment of the present invention includes a self-contained housing, a backup power supply, and an output swit... | 06/15/1999 |
| 5908773 | KSHV positive cell lines The invention provides a cell line comprising Kaposi's sarcoma-associated herpesvirus (KSHV). Preferably, the cell line is a body cavity-based lymphoma cell line, and more preferably, the cell line does not harbor Epstein-Barr virus. Two cell lines design... | 06/01/1999 |
| 5907085 | Grapevine leafroll virus proteins and their uses The present invention relates to an isolated protein or polypeptide corresponding to a coat protein or polypeptide of a grapevine leafroll virus. The encoding DNA molecule either alone in isolated form or in an expression system, a host cell, or a transge... | 05/25/1999 |
| 5889132 | Dental material A dental material is described which is characterized by a content of silicic acid condensates of norbornene or mercapto silanes, and which, after thiol-ene polymerisation with suitable reactants, shows only slight polymerisation shrinkage and produces po... | 03/30/1999 |
| 5886212 | Multifunctional vinyl cyclopropane derivatives Multifunctional polymerizable vinyl cyclopropane derivatives are described which have at least two vinyl cyclopropane units and are suitable in particular as a constituent of dental materials.... | 03/23/1999 |
| 5886064 | Fine-grained polymerizable compositions flowable under pressure or shear stress A granular, polymerizable composition which contains at least one polymerizable monomer and/or oligomer and a polymerization initiator and optionally an accelerator and at least 70% by wt. filler and additionally 0.5 to 28% by wt. dendrimer and which beco... | 03/23/1999 |
| 5876994 | Pheromone desaturases The present invention is directed to isolated membrane-associated acyl-CoA desaturases expressed in the pheromone gland of an insect and, in particular, the Ɗ11 desaturase of Trichoplusia ni. The present invention further relates to an isolated DNA molec... | 03/02/1999 |
| 5871940 | Assays for modulators of drosophila cation channel function Genomic and cDNA clones corresponding to the tipE gen of Drosophila melanogaster are described. The tipE protein functions in concert with the para gene product, a polypeptide which exhibits similarity to mammalian voltage-dependent sodium channel ... | 02/16/1999 |
| 5869152 | Silica materials The present invention relates to silica materials and particles having surfaces which define an interior. The interior includes interior silicon atoms at least a portion of which is bonded to a substituted or unsubstituted alkyl moiety. In a preferred asp... | 02/09/1999 |