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| Number | Title | Issue Date |
| 4868344 | Novel process of producing phenyl or substituted phenylalkylamine pharmaceutical agents and novel chiral intermediates of high enantiomeric purity useful therein A process for producing the optically pure (+)- or (-) isomer of a phenyl- or substituted- phenylalkanolamine compounds having pharmacologic activity without the need for resoltuion processes ad novel intermediates useful in the process including opticall... | 09/19/1989 |
| 4868337 | Optically active borinic esters and ketones A process for synthesizing an optically pure ketone comprising the steps of: treating an appropriate optically pure boronic ester with an organolithium compound at -78° C. to obtain the "ate" complex, separating the optically pure borinic ester from the ... | 09/19/1989 |
| 4795821 | Optically active borinic esters and ketones A process for synthesizing an optically pure ketone comprising the steps of: treating an appropriate optically pure boronic ester with an organolithium compound at -78° C. to obtain the "ate" complex, separating the optically pure borinic ester from the ... | 01/03/1989 |
| 4772751 | Process for lithium mono- and diorganylborohydrides Improved processes for liberating boronic, RB(OR')2, and borinic, RR'BOR', esters from their "ate" complexes, free of alcohol are provided. Pyrolysis of lithium organylborates LiRB(OR')3 and LiRR'BOR', wherein R is an organyl group a... | 09/20/1988 |
| 4772752 | Mono- and diisopinocampheylhaloboranes as new chiral reducing agents Novel mono- and diisopinocampheylhaloboranes, represented by the formulae IpcBX2 and Ipc2 BX wherein Ipc is isopinocampheyl and X is halo, as well as processes for making and using same.... | 09/20/1988 |
| 4441538 | Flexible container with integral ports and diaphragm A container for liquids, preferably sterile liquids comprises a hollow body constructed of plastic material having a plurality of tubular ports integrally formed and extending therefrom. Each port has a quantity of plastic material integrally formed as a ... | 04/10/1984 |
| 4421673 | Catalyst for making polyurethanes Polyurethane foams with excellent physical properties can be obtained by using a partial salt between N,N-dimethylaminopropane-1,3-diamine (DMAPA) and a branched octanoic acid.... | 12/20/1983 |
| 4420568 | Fluorescent polarization immunoassay utilizing substituted triazinylaminofluoresceins An immunochemical method and reagent compounds for determining ligands in a sample. The reagent compounds are derivatives of a triazinylaminofluorescein and are represented by the structural formula ##STR1## wherein Y is halo or lower alkyl; and R is... | 12/13/1983 |
| 4417577 | Gravitational flow system for the sequential administration of medical liquids A gravitational flow system for the sequential administration of medical liquids to a patient comprises a primary container connected to a primary tube, a secondary container connected to a secondary tube, and a combined air barrier and liquid sequencing ... | 11/29/1983 |
| 4405312 | Connecting device for medical liquid containers A connecting device for medical liquid administration sets, particularly for use in continuous ambulatory peritoneal dialysis comprises a tubular port extending from a medical liquid container. The tubular port has a pierceable diaphragm positioned within... | 09/20/1983 |
| 4405053 | Tamperproof closure system for plastic containers An improved tamperproof closure system for molded plastic containers has a threaded neck portion sealed at its distal end, and a screw-cap designed for attachment to the container neck. A flange extends radially from the container neck and a frangible ann... | 09/20/1983 |
| 4397442 | In-line sleeve valve An improved in-line sleeve valve comprises a modular tubular port having a stationary plug concentrically supported therein and a reciprocating tubular sleeve arranged for sealing against the stationary plug. A resilient, flexible flange connects the tubu... | 08/09/1983 |
| 4392851 | In-line transfer unit A sterile container for a medicinal material which is to be intermixed in an I.V. solution wherein the container serves as a mixing device as well as a portion of an I.V. administration apparatus. The device of this invention includes a container which is... | 07/12/1983 |
| 4392850 | In-line transfer unit A sterile container for a medicinal material which is to be intermixed in an I.V. solution wherein the container serves as a mixing device as well as a portion of an I.V. administration apparatus. The device of this invention includes a container which is... | 07/12/1983 |
| 4391028 | Solventless assembly of flexible tubing to a component An apparatus for facilitating assembling a length of flexible tubing on a component part which avoids the use of sealing solvents yet affords a secure placement of the tubing thereon. The apparatus and method assures a secure fitment by stretching the tub... | 07/05/1983 |
| 4389210 | Catheter placement assembly having axial and rotational alignment means A needle-inside, catheter placement assembly including a spliced, two-part needle and a catheter unit comprising a catheter, winged catheter insertion means, flexible tubing and tube hub, wherein axial and rotational alignment of the needle and catheter u... | 06/21/1983 |
| 4389416 | Diphenyl ether, diphenyl thioether and diphenyl methane phenol mannich bases Described are compounds of the formula ##STR1## wherein R is hydrogen, loweralkyl, aminomethyl or halo; R1 is carboxy, carboxyloweralkyl, aminocarbonyl, hydroxymethyl, anilinomethyl, or aminomethyl; A is oxygen, CH2, Sulfur or a... | 06/21/1983 |
| 4388074 | Winged catheter placement assembly A needle-inside, catheter placement assembly including needle and catheter units. The needle unit comprises a needle joined by a flexible line to a needle hub. The catheter unit comprises a catheter, winged catheter insertion means, flexible tubing and tu... | 06/14/1983 |
| 4382453 | Flow ristrictor for flexible tubing A flow control device which will limit the maximum flow rate of liquid through a length of flexible tubing such as utilized in a parenteral administration set so as to prevent a runaway condition. A base and a cover member are provided which are hingedly ... | 05/10/1983 |
| 4375478 | Aminobenzoic acid derivatives Described are compounds of the formula ##STR1## wherein Y and Z independently of one another denote hydrogen, halo or trihalomethyl, with the proviso that Y and Z cannot both be hydrogen, R is hydrogen or loweralkyl, n is 5 to 19, and pharmaceuticall... | 03/01/1983 |
| 4373559 | Apparatus for pressurizing an additive transfer device A pressurized additive transfer device for storing and transferring of a fluid material to a solution container such as a rigid container or an I.V. bag having an exposed pierceable closure or port. The transfer device is self-pressurized and includes a c... | 02/15/1983 |
| 4372306 | Equipment sets having a combined air barrier and liquid sequencing device for the sequential administration of medical liquids at dual flow rates Equipment sets for the sequential administration of medical liquids allow primary liquid to be administered at a flow rate independent of the flow rate of a secondary liquid. The sets include a combined air barrier and liquid sequencing device to prevent ... | 02/08/1983 |
| 4371546 | Benzophenone derivatives Described are compounds of the formula ##STR1## wherein R is hydrogen, loweralkyl, aminomethyl or halo, R1 is hydroxy or NHX where X is H, loweralkyl, phenyl, substituted phenyl, acetyl, benzyl and substituted benzyl, and Y is hydrogen, lo... | 02/01/1983 |
| 4370992 | Washing apparatus for small parts A washing apparatus for small parts which will permit the loading of the parts into the apparatus in a fast and efficient manner and at the same time will afford maximum cleaning of the parts. The particular component parts for which the machine is specif... | 02/01/1983 |
| 4370417 | Recombinant deoxyribonucleic acid which codes for plasminogen activator The present invention provides a deoxyribonucleic acid (DNA) segment related to a human plasminogen activator gene. The segment is inserted into a plasmid vector which in turn can be incorporated into a bacterium or other microorganism. The bacterium can ... | 01/25/1983 |
| 4368765 | Flexible bag with recessed scrapless hanger A hanger construction for a collapsible container for medical fluids which is fabricated in such a manner that it is scrapless and positioned within the confines of the container. The hanger is formed with tear and hinge lines so that one or more tab port... | 01/18/1983 |
| 4366816 | Combination quick disconnect coupling and fluid cutoff valve A combination quick disconnect coupling and fluid cutoff valve particularly adapted for use in continuous ambulatory peritoneal dialysis comprises a first tubular member connected to a length of flexible tubing and having a fluid passageway therethrough, ... | 01/04/1983 |
| 4364387 | Connecting device for medical liquid containers An improved connecting device for medical liquid containers comprises an elongated tubular member having a lumen extending therethrough. Pivotable finger tabs are hingedly attached to and extend from the elongate tubular member, adapted for engagement wit... | 12/21/1982 |
| 4363321 | I.V. Administration flow rate gauge An apparatus for measuring the flow of medical liquids within an intravenous solution administration set comprises a primary tube, a secondary tube and a tertiary tube. A constricter mechanism is positioned in the primary tube proximate the opening to the... | 12/14/1982 |
| 4353369 | Venipuncture device An improved venipuncture device comprises a catheter having a catheter hub at one end, with a needle having a needle hub at one end and a sharpened tip at the second end extending through the catheter and catheter hub. A resilient reseal is mounted in the... | 10/12/1982 |
| 4349023 | Epidural needle catheter and adapter A device which will permit the introduction of a length of catheter tubing through a needle and into the epidural space of a patient wherein the chance of the tubing being kinked is substantially reduced. In one version, an adapter having two opposing pro... | 09/14/1982 |
| 4331804 | 2-Epi-fortimicin A and derivatives What is described is 2-epi-fortimicin A, 2-epi-fortimicin B or a 2-epi-fortimicin B derivative represented by the formula: ##STR1## wherein R1 is hydrogen or loweralkyl; R2 is hydrogen or hydroxy; R3 is methyl or hydr... | 05/25/1982 |
| 4331589 | Deoxyribonucleic acid synthesis using binding protein extracted from chick embryo fibroblasts Described is a method of obtaining complete copying of the entire length of single stranded ribonucleic acid (RNA) into its complementary deoxyribonucleic acid (cDNA) by reverse transcription using binding protein. The method can be used in recombinant DN... | 05/25/1982 |
| 4326033 | Modified urokinase having extended activity and method of making Described is a structurally modified urokinase which is biologically active over an extended time period in comparison to native urokinase. The extended activity permits the administration of lower doses of urokinase when it is used in the treatment of th... | 04/20/1982 |
| 4324242 | Feminine syringe A two-step release valve unit for a feminine syringe wherein a valve member and nozzle serve to open and close a dispensing port for an expandable syringe bag. The valve unit includes a slidable nozzle member which in one position will open a valve elemen... | 04/13/1982 |
| 4323691 | Hydroxyaminomethyl derivatives of benzoyl di-substituted -phenoxyalkanoyl esters Described are compounds of the formula ##STR1## wherein ##STR2## wherein Z is hydrogen or loweralkyl, R5 and R6 may be the same or different and are hydrogen, loweralkyl or together are alkylene of 4 or 5 carbon atoms,... | 04/06/1982 |
| 4317363 | Elastomer instrument An elastometer for measuring the mechanical strength of biological gels such as blood or fibrin clots. Thus this device may be used for accessing anticoagulant and fibrinolitic activities, particularly with respect to drug evaluation. The instrument can a... | 03/02/1982 |
| 4317904 | 1,2-Epiminofortimicin B A new fortimicin antibiotic, 2-deoxyfortimicin B, intermediates useful in the preparation of the compound, methods of making and using the compound and compositions containing 2-deoxyfortimicin B.... | 03/02/1982 |
| 4316460 | Gravitational flow system for the sequential administration of medical liquids A gravitational flow system for the sequential administration of medical liquids to a patient comprises a primary container connected to a primary tube, a secondary container connected to a secondary tube, and a combined air barrier and liquid sequencing ... | 02/23/1982 |
| 4313904 | Method of manufacturing a flexible container with integral ports and diaphragm A container for liquids, preferably sterile liquids comprises a hollow body constructed of plastic material having a plurality of tubular ports integrally formed and extending therefrom. Each port has a quantity of plastic material integrally formed as a ... | 02/02/1982 |
