Celebrity Inventors
Magician Harry Houdini patented a "Diver's Suit" enabling the wearer to "quickly divest himself of the suit while being submerged and to safely escape and reach the surface of the water."
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| PP22715 | plant named ‘Tonda Pacifica’ A new and distinct cultivar of Corylus plant named ‘Tonda Pacifica’ is provided. ... | 05/08/2012 |
| 8168222 | Amphiphilic polymer-protein conjugates and methods of use thereof Compositions and methods for transporting biologically active proteins and polypeptides, particularly across the blood-brain barrier, are provided. ... | 05/01/2012 |
| 8137699 | Process and apparatuses for preparing nanoparticle compositions with amphiphilic copolymers and their use This invention discloses a process for making nanopanticles of amphiphilic copolymers by flash precipitation. Nanoparticles may be of amphiphilic copolymer alone or may contain an additive target molecule, preferably an organic active. The inclusion of additive targ... | 03/20/2012 |
| 8123798 | Biofilm formation inhibitor and treatment device thereof A treatment device such as a biliary stent, capable of effectively and continuously inhibiting biofilm formation, and a biofilm formation inhibitor suitable for coating on the treatment device by killing all bacteria including E. coli and by suppressing the g... | 02/28/2012 |
| 8119369 | Human SUMO-3 for enhancing protein expression The inventive subject matter relates to novel compositions, methods, and kits for enhancing the expression, solubility, and isolation of heterologous proteins. Further, the inventive subject matter relates to methods for generating proteins with novel N-terminal ami... | 02/21/2012 |
| 8071289 | Synthesis of hybrid polynucleotide molecules using single-stranded polynucleotide molecules A method to make libraries of hybrid polynucleotide molecules of two parental polynucleotide molecules utilizing single-stranded DNA was invented. Example of the method comprises several steps: (i) preparation of two single-stranded polynucleotide molecules comprisi... | 12/06/2011 |
| 8058416 | Nucleic acid molecules encoding indoleamine 2,3-dioxygenase-2 The nucleotide and amino acid sequences of indoleamine 2,3-dioxygenase-2 (IDO2) and methods of use thereof are provided. ... | 11/15/2011 |
| 8034780 | Isolation, purification, and structure elucidation of the antiproliferative compound coibamide A Novel antiproliferative compounds, compositions comprising the same, and methods of use thereof are disclosed. ... | 10/11/2011 |
| 8008318 | 39-desmethoxy derivatives of rapamycin The present invention relates to 39-desmethoxyrapamycin derivatives and their uses thereof. The present invention provides for the use of these compounds in the treatment of cancer and/or B-cell malignancies, the induction or maintenance of immunosuppression, the tr... | 08/30/2011 |
| 8008281 | Methods for the treatment of cancer Compositions and methods for the treatment of malignancy and chronic viral infection are disclosed. ... | 08/30/2011 |
| 7994147 | Cellular genes regulated by HIV-1 infection and methods of use thereof This invention provides cellular gene products which have anti-apoptotic activity in HIV-1 infected cells and provides agents for the inhibition of the cellular gene products. ... | 08/09/2011 |
| 7985836 | Antimicrobial peptides and methods of identifying the same Antimicrobial peptides and methods of identifying the same are provided. ... | 07/26/2011 |
| 7968682 | Degradation-resistant fibrinogen sealants Provided are degradation-resistant fibrinogen sealants comprising a first composition comprising one or more of fibrinogen γA/γ′ heterodimers and/or fibrinogen γ′/γ′ homodimers and a second composition comprising thrombin and, optionally, degradation-resis... | 06/28/2011 |
| 7879823 | Topical anti-cancer compositions and methods of use thereof Described are skin-care compositions containing non denatured soy products and optionally other anti-cancer or anti-aging agents. The compositions can be applied topically to reduce the risk of UV-induced cutaneous tumors. ... | 02/01/2011 |
| 7842460 | Method for assessing proteolytic enzyme activity using ubiquitin fusion substrate Methods and kits for assessing proteolytic enzyme activity and a modulator's effect thereof employ a Ubiquitin or Ubiquitin-like Protein and a signal producing structure. The corresponding fusion polynucleotide is employed for production of transgenic cells, plants ... | 11/30/2010 |
| 7820384 | Methods and compositions for protein expression and purification Methods for enhancing expression levels and secretion of heterologous fusion proteins in a host cell are disclosed. ... | 10/26/2010 |
| 7816334 | Materials and methods relating to immune responses to fusion proteins The invention provides nucleic acid construct and nucleic acid expression vectors directing the expression of a fusion protein consisting of a disease peptide antigen and a first domain of FrC of tetanus toxin. The invention provides nucleic acid (DNA) vaccines for ... | 10/19/2010 |
| 7816085 | Method for in vitro molecular evolution of protein function The invention provides a method for generating a polynucleotide sequence or population of sequences from parent single stranded polynucleotide sequences encoding one or more protein motifs, comprising the steps of a) providing single stranded DNA constituting plus a... | 10/19/2010 |
| 7740914 | Method to manufacture metallized paper with curtain coating The method comprises the stages of the curtain coating of a first aqueous film-forming composition on a substrate; and the curtain coating of a second aqueous film-forming composition on said metallized substrate, characterized in that said first and second aqueous ... | 06/22/2010 |
| 7723564 | Compositions and methods for modulation of KSR1 and KSR2 interactions Materials and methods for identifying agents which modulate KSR mediated signal transduction are provided. ... | 05/25/2010 |
| 7696306 | Compositions and methods for preventing or treating cancer The present invention relates to a MUC1 cytoplasmic tail peptide or portion thereof. These peptides are useful for inducing an immune response to MUC1-expressing tumor cells and thus for preventing or treating cancer. ... | 04/13/2010 |
| 7683236 | Enhanced production of cloned mammals by zona pellucida-free homologous mammalian embryo aggregation Compositions and methods are provided for the efficient and reproducible generation of clone animals of all developmental stages. Also provided are methods of use of the same in reproductive and therapeutic cloning protocols. ... | 03/23/2010 |
| 7662939 | Molecular determinants of tropism and virulence in enteroviruses Recombinant enteroviruses for use as vaccines or vectors, which are modified in tropism or virulence, are disclosed. Also disclosed are DNA constructs comprising enterovirus-derived molecular determinants of tropism or virulence for use in targeting genes of interes... | 02/16/2010 |
| 7655413 | Methods and compositions for enhanced protein expression and purification Methods for enhancing expression levels and secretion of heterologous fusion proteins in a host cell are disclosed. ... | 02/02/2010 |
| 7615527 | Peptides which modulate blood coagulation and methods of use thereof Peptide fragments that modulate thrombosis and methods of use thereof are provided. Also provided are synthetic bioactive anti-coagulation peptides, compositions comprising such peptides and methods for the administration to patients in need thereof. ... | 11/10/2009 |
| 7589174 | GRP94-based compositions and methods of use thereof Mini chaperones and methods of use thereof for the treatment of cancer and other disorders are provided. Also provided are tools to facilitate screening therapeutic agents which have selective binding affinity for GRP94. ... | 09/15/2009 |
| 7563578 | Method for in vitro molecular evolution of protein function The invention provides a method for generating a polynucleotide sequence or population of sequences from parent single stranded polynucleotide sequences encoding one or more protein motifs, comprising the steps of a) providing sing... | 07/21/2009 |
| 7560252 | Borrelidin-producing polyketide synthase and its use The present invention relates to the biosynthesis of polyketides and derives from the cloning of nucleic acids encoding a polyketide synthase and other associated proteins involved in the synthesis of the polyketide borrelidin. Materials and methods including enzyme... | 07/14/2009 |
| 7468250 | Methods and kits for screening nucleic acid duplex stability Simple methods and kits for determining the thermodynamic stability of nucleic acid duplexes and single polynucleotide polymorphisms via competitive equilibria are provided. ... | 12/23/2008 |
| 7422875 | Compositions and methods for increasing protein production Compositions and methods for increasing protein production are provided. ... | 09/09/2008 |
| 7402405 | Methods and kits for diagnosing a pancreatic-based fat malabsorption disorder The present invention relates to methods and kits useful in the diagnosis of a pancreatic-based fat malabsorption disorder in a mammal. ... | 07/22/2008 |
| 7291336 | Compositions and methods for enhancing immune responses mediated by antigen-presenting cells Molecular adjuvants are disclosed comprising an antigen presenting cell-targeting ligand functionally linked to an immunogen, e.g. tumor associated antigens, bacterial or viral antigens, etc. Methods are disclosed for delivery of these molecular adjuvants to patient... | 11/06/2007 |
| 7238524 | Prostate cancer cell lines Novel human prostate cancer-associated neuroendocrine (NE)-like cell lines are provided that were derived via a process that resembles clinical androgen ablation therapy for advanced prostate cancer. ... | 07/03/2007 |
| 7211434 | Primitive neural stem cells and method for differentiation of stem cells to neural cells Described are a novel cell type in the neural lineage, and method of producing the same based on the degree of neural commitment and growth factor responsiveness in vitro and the potential to give rise to neural and non-neural progeny in vivo. The novel vell type of... | 05/01/2007 |
| 7211558 | Compositions and methods for the treatment of hemophilia A Improved materials and methods for the treatment of Hemophilia A are provided. ... | 05/01/2007 |
| 7208583 | Antibodies immunologically specific for a DNA repair endonuclease and methods of use thereof An isolated nucleic acid molecule encoding a human DNA repair enzyme, MED1, is disclosed. Like other mismatch repair genes which are mutated in certain cancers, MED1, encoding nucleic acids, proteins and antibodies thereto may be used to advantage in genetic or canc... | 04/24/2007 |
| 7183289 | 39-desmethoxyrapamycin, compositions and methods of use thereof The present invention relates to medical uses of 39-desmethoxyrapamycin. ... | 02/27/2007 |
| 7169966 | Salicylic acid-binding protein encoding nucleic acid, SABP2, and methods of use thereof Novel nucleic acid molecules encoding SA-binding proteins involved in SA-mediated disease resistance responses are disclosed. Methods of use of the nucleic acid molecules and proteins of the invention are also provided. ... | 01/30/2007 |
| 7153655 | Method for in vitro molecular evolution of protein function involving the use of exonuclease enzyme and two populations of parent polynucleotide sequence The present invention relates to a method for in vitro evolution of protein function. In particular, the method relates to the shuffling of nucleotide segments obtained from exonuclease digestion. The present inventors have shown that polynucleotide fragments derive... | 12/26/2006 |
| 7087371 | Material and methods for the production of sperm and analysis thereof Provided herein are methods of producing viable sperm from neonatal mammalian testes which have been engrafted in mice. ... | 08/08/2006 |
