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| Number | Title | Issue Date |
| 7659246 | Treatment of osteoarthritis This invention relates to methods of treatment of osteoarthritis, and especially to treatment of this condition with cyclic peptidic and peptidomimetic compounds which have the ability to modulate the activity of G protein-coupled receptors. The compounds preferably... | 02/09/2010 |
| 7589170 | Synthesis of cyclic peptides This invention relates to methods for preparing cyclic peptides and peptidomimetic compounds in solution and bound to solid supports, and to cyclic peptide or peptidomimetic libraries for use in drug screening programs. In particular, the invention relates to a gene... | 09/15/2009 |
| 7579432 | Cyclic peptides as G-protein-coupled receptor antagonists The invention relates to novel cyclic compounds which have the ability to modulate the activity of G protein-coupled receptors. The compounds preferably act as antagonists. In preferred embodiments, the invention provides cyclic peptidic and peptidomimetic antagonis... | 08/25/2009 |
| 7417129 | Combinatorial libraries of monosaccharides A monosaccharide compound of formula I as shown in the specification. Processes for the preparation of the compound of formula I and methods of screening for antibacterial or antibiotic compounds involving the compound of formula I. ... | 08/26/2008 |
| 7410945 | Treatment of inflammatory bowel disease This invention relates to methods of treatment of inflammatory bowel disease, and especially to treatment of this condition with cyclic peptidic and peptidomimetic compounds which have the ability to modulate the activity of G protein-coupled receptors. The compound... | 08/12/2008 |
| 7342111 | Adeno-associated virus-delivered ribozyme compositions and methods of use Provided are methods for the identification of novel genes involved in a variety of cellular processes, including retinal degeneration, retinal disease, cancer, memory and learning, amylotropic lateral sclerosis, and methods for the identification of the function of... | 03/11/2008 |
| 7323323 | Preparation and xenotransplantation of porcine islets The invention relates to developments in the treatment of diabetes in mammals. Particularly it relates to a method of preparing a xenotransplantable porcine islet preparation capable upon xenotransplantation of producing porcine insulin in an appropriate recipient m... | 01/29/2008 |
| 7312194 | Delivery systems The invention relates to compounds which are useful in the delivery of a wide variety of therapeutically useful molecules. In particular, the invention relates to compounds which are able to act as carriers for therapeutically useful molecules, and to pharmaceutical... | 12/25/2007 |
| 7304129 | Peptides that stimulate cell survival and axon regeneration Peptides which consist of or comprise the tetrameric peptide structural unit: Xaa-Xaa-Xaa-Xaa in which Xaa at position 1 represents Glu or Asp, Xaa at position 2 represents any amino acid, Xaa at position 3 represents any amino acid and Xaa at p... | 12/04/2007 |
| D540155 | Shackle | 04/10/2007 |
| 7122177 | Preparation and xenotransplantation of porcine islets The invention relates to developments in the treatment of diabetes in mammals. Particularly it relates to a method of preparing a xenotransplantable porcine islet preparation capable upon xenotransplantation of producing porcine insulin in an appropriate recipient m... | 10/17/2006 |
| 7018836 | P-TEFb compositions, methods and screening assays Disclosed is the discovery that the transcription elongation factor termed P-TEFb has a central role in transcription elongation control. P-TEFb is herein shown to phosphorylate RNA polymerase II and to control the transition from abortive into productive elongation... | 03/28/2006 |
| 6953850 | Protecting groups for carbohydrate synthesis The invention provides collections of orthogonally-protected monosaccharides as universal building blocks for the synthesis of glycoconjugates of non-carbohydrate molecules, neo-glycoconjugates and oligosaccharides. This orthogonal protection strategy allows for the... | 10/11/2005 |
