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| Number | Title | Issue Date |
| 7737191 | Rubber treatment method A process and resulting product is provided in which vulcanized rubber crumb has selected chemical bonds broken and sulphur removal by biotreatment with hydrophobic bacteria, such as mycolic acid containing actinomycete bacteria of ‘mycolata’, without significan... | 06/15/2010 |
| 7737109 | Obesity controlling method A method of controlling obesity by physically narrowing the lumen of the pylorus One embodiment includes injection of a bio-compatible bulking or stiffening material into the pyloric sphincter area of the stomach. The injection of this material bulks the pyloric sph... | 06/15/2010 |
| 7723095 | Method for cellular lysis of prokaryotes or eukaryotes or simultaneous cellular lysis of prokaryotes and eukaryotes A method for lysing prokaryotic or eukaryotic cells, or for simultaneous lysis of both, which includes at least three of the following: a mass of active, small-diameter beads corresponding to 50% or less than a mass of active, larger-diameter beads, and/or a total m... | 05/25/2010 |
| 7695724 | Recombinant rabies virus compositions Recombinant rabies viruses in which the arginine residue of the glycoprotein (G) at amino acid position 333 is exchanged, renders these viruses nonpathogenic for immunocompetent mammals regardless of the route of infection. Some of these recombinant rabies viruses a... | 04/13/2010 |
| 7674839 | Methods for the production of polymer carrier materials based on carbon hydrate-bis(meth)acryl-amides The invention relates to methods for the production of polymer carrier materials for solid phase synthesis, particularly for peptide synthesis. (Meth)acrylamide derivatives based on carbon hydrates, which can also contain other protective groups, are polymerized by ... | 03/09/2010 |
| 7674780 | Iron sucrose complexes and method of manufacture thereof A process is provided for preparing an iron sucrose complex, substantially free of excipients, for providing an iron sucrose complex co-precipitated with sucrose, and for providing iron sucrose complexes in aqueous solution. ... | 03/09/2010 |
| 7645858 | Method of peptide synthesis of peptides containing a proline residue or hydroxyproline residue at or adjacent to the C-terminal end of the peptide A method for synthesizing a given peptide or its derivative which contains a proline residue or a proline derivative, at proximity to, or at, the C-terminal end of said peptide is provided. The method comprises a) synthesizing on a first resin a C-terminal portion o... | 01/12/2010 |
| 7622552 | Ligation method A method of ligating two or more molecules, for example, peptides to peptides or peptides to labels is provided. The method may comprise the steps: a) providing a first oligopeptide having a reactive moiety, which is a hydrazine moiety, a hydrazide moiety or an amin... | 11/24/2009 |
| 7622446 | Polypeptides, derivatives and uses thereof The invention provides a compound having formula X1-Arg-Xaa-Arg-X2 in which X1 and X2 are up to 30 amino acid residues and Xaa is an amino acid residue. A preferred compound is the tripeptide Arg-Glu-Arg which corresponds ... | 11/24/2009 |
| 7618779 | Chromosome 1p36 polymorphisms and low bone mineral density The invention provides methods and compositions for diagnosing risk of low BMD and risk of osteoporosis based on the detection of SNP identity for human chromosome 1p36 polymorphisms designated in the NCBI SNP database (dbSNP) as rs2794328, rs446529, rs397559 and rs... | 11/17/2009 |
| 7612039 | Method of cell growth inhibition with agnoprotein The growth of normal and abnormally proliferating cells can be inhibited by the introduction of agnoprotein, or biologically active fragments or derivatives of agnoprotein, into the cell in the absence of any other polyoma virus protein or viral replication. ... | 11/03/2009 |
| 7598232 | Amino-substituted ()-2,6-dialkoxystyryl 4-substituted-benzylsulfones for treating proliferative disorders Compounds useful as antiproliferative agents, including, for example, anticancer agents, are provided according to formula (I); wherein: X, X1, X2, Ra, R1, R2,R3, R4, R5, R6... | 10/06/2009 |
| 7595347 | Method for protecting normal cells from cytotoxicity of chemotherapeutic agents Pre-treatment with α,β unsaturated aryl sulfones protects normal cells from the cytotoxic side effects of two classes of anticancer chemotherapeutics. Administration of a cytoprotective sulfone compound to a patient prior to anticancer chemotherapy with a mitotic ... | 09/29/2009 |
| 7575858 | Method of visualizing proteins bound to protein-binding membranes A method of visualizing proteins bound to a protein-binding membrane is provided herein, comprising reacting proteins bound to protein-binding membranes with a compound of formula (I) wherein Ra, R1, R2, R3, R4,... | 08/18/2009 |
| 7563592 | Alizarin-based chromogenic substrates, their uses and composition containing same An alizarin-based chromogenic substrate, a composition containing the substrate, and its use to detect the presence of an enzymatic activity are disclosed. The substrate is particularly applicable in the field of biological diagnosis. ... | 07/21/2009 |
| 7547547 | Bioprocess for producing uniform embryoid bodies from embryonic stem cells in a high density bioreactor The present inventors identified aggregation of embryonic stem cells and embryoid bodies (EBs) as the cause of the difficulty in generating large numbers of the embryonic stem cells (ES) cell-derived tissues. To counter this, the invention provides a novel bioproces... | 06/16/2009 |
| 7541355 | Conversion process for 2,3-benzodiazepine enantiomers Methods for the racemization of an enantiomer of a 2,3-benzodiazepine molecule into the corresponding racemic mixture under either basic or acidic conditions are described. Furthermore, the invention relates to the conversion of an enantiomer of tofisopam or its met... | 06/02/2009 |
| 7538087 | Agent against periodontal disease The present invention relates to a product for preventing periodontal disease wherein the product includes or is based on a Cystatin type peptide. The invention also relates to dentifrice preparations including Cystatin and to medicaments including Cystatin for the ... | 05/26/2009 |
| 7517653 | Immunological test and diagnostic kit for prostate adenocarcinoma This invention concerns a test method for the purposes of diagnosis, prognosis or therapeutic monitoring in male patients with adenocarcinoma of the prostate or benign prostatic hyperplasia, which does not require a biopsy of prostate tissue, and which exploits the ... | 04/14/2009 |
| 7498138 | Multimerization of HIV-1 Vif protein as a therapeutic target The HIV-1 protein Vif comprises a multimerization domain that allows Vif-Vif interaction and Vif multimerization, which is important for Vif function in the HIV-1 life-cycle. A method for screening for an antagonist of Vif comprises contacting the multimerization do... | 03/03/2009 |
| 7498054 | Method for controlling solute loading of polymer microparticles Solute-loaded polymer microparticles are obtained by immersing microparticles in a bath comprising a selected solute dissolved in a ternary solvent system. A first solvent of the ternary system is a strong solvent for both the solute and the polymer from which the m... | 03/03/2009 |
| 7495384 | Display comprising a fluorescent dye doped polymer The present invention provides a dynamic high resolution color display. In particular a display comprising a plurality of pixels composed of a fluorescent dye doped polymer material is provided. Specifically said pixels are applied to a suitable base substrate and f... | 02/24/2009 |
| 7482488 | Aryl and heteroaryl propene amides, derivatives thereof and therapeutic uses thereof Compounds useful as antiproliferative agents, radioprotective agents and cytoprotective agents, including, for example, anticancer agents, are provided according to formula I: wherein ring A, ring B,,X, R1, R2, R3, a, and b are as de... | 01/27/2009 |
| 7465724 | Bis-pyrrolo[2,1-c][1,4]benzodiazepine-anthraquinone conjugates and a process for the preparation thereof The present invention provides novel bis-pyrrolo[2,1-c][1,4]benzodiazepine-anthraquinone conjugates of general formula V, useful as potential antitumour agents against human cancer cell lines. The present invention further provides a process for the preparation of n... | 12/16/2008 |
| 7407775 | Method for identifying and culture medium A substrate which can be used for the direct identification of pathogenic bacteria belonging to the genus Listeria by detecting an esterase activity other than Phosphatidyl Inositol-specific Phospholipase C (PI-PLC), an esterase which is specific to the speci... | 08/05/2008 |
| 7279151 | Herbal oro-dental care composition and process for preparing the same This invention relates to novel dental compositions and methods for preventing dental plaque and caries formation and generally for inhibiting tooth decay and brightening/whitening teeth. The compositions of this invention comprise herbs such as Citrus karna ... | 10/09/2007 |
| 7265106 | Method for isolating ()-tofisopam (R)-tofisopam, substantially free of the (S)-enantiomer of tofisopam, is obtained by separating the enantiomers of tofisopam by chromatography employing a chiral separation medium comprising (i) (2S)-2-{(1S)[(3,5-dinitrophenyl)carbonylamino]phenylmethyl}-3,3-dimethy... | 09/04/2007 |
| 7259005 | Microorganism having ability to convert sterol into androst-4-ene-3, 17-dione/androsta-1,4-diene-3, 17-dione and preparation method and use thereof Disclosed is a microorganism having an excellent ability to convert sterol into and rost-4-ene-3,17-dione (AD) and androsta-1,4-diene-3,17-dione (ADD), a method for preparation of the microorganism and use thereof, and more particularly, a mutant strain of Mycoba... | 08/21/2007 |
| 7259291 | Enucleation of avian eggs by gamma irradiation A method of enucleating an egg by exposing the egg to gamma irradiation. The dose of gamma irradiation used is sufficiently high to halt development of the egg or embryo derived therefrom directed by the nucleus of the irradiated egg, but sufficiently low to enable ... | 08/21/2007 |
| 7259140 | Heparin-binding peptides and uses thereof Heparin-binding peptides are provided of the formula R1(X1B1B2X2B3X3Y1R2)RnR3, R1(X1B1B2B3... | 08/21/2007 |
| 7241589 | Method for preparation of androst-4-ene-3,17-dione and androsta-1,4-diene-3,17-dione The present invention relates to a method for preparation of androst-4-ene-3,17-dione (AD) and androsta-1,4-diene-3,17-dione (ADD). More particularly, the present invention relates to a method for preparing AD/ADD, comprising the steps of: (a) heating sterols and em... | 07/10/2007 |
| 7226741 | Multimerization of HIV-1 Vif protein as a therapeutic target One approach to treating individuals infected with HIV-1 is to administer to such individuals compounds that directly interfere with and intervene in the machinery by which HIV-1 replicates itself within human cells. Although the specific role of HIV-1 viral protein... | 06/05/2007 |
| RE39681 | 1-(4-sulfamyaryl)-3-substituted-5-aryl-2-pyrazolines and inhibitors of cyclooxygenase-2 Compounds of the formula wherein: X is selected from the group consisting of trihalomethyl, C1-C6 alkyl, and a group of formula II: ... | 06/05/2007 |
| 7223584 | Recombinant rabies vaccine and methods of preparation and use Live rabies virus vaccines comprising a recombinant rabies virus genome which overexpresses the rabies virus G protein increase apoptotic activity in infected cells, and enhance the generation of anti-rabies immunity in a subject. ... | 05/29/2007 |
| 7223550 | Biosensor for defecting chemical agents A biosensor for the identification of olfactants, including chemical and biological agents, prefumery, explosives and pharmaceuticals. The biosensors comprise robust eukaryotic cells, such as yeast, into which at least one exogenous olfactory signaling pathway has b... | 05/29/2007 |
| 7220394 | Process for simultaneous recovery of chromium and iron from chromite ore processing residue The present invention relates to a process for simultaneous recovery of chromium and iron from Chromite Ore Processing Residue (COPR) and more particularly, the present invention relates to an economical and environment-friendly process for recovering chromium as a ... | 05/22/2007 |
| 7211650 | Purification of fibrinogen from fluids by precipitation and hydrophoic chromatography The present invention provides a method for the part purification of fibrinogen from milk, the method comprising the transfer of protease enzyme which is present in the milk, into the whey phase with the removal or partition if fibrinogen into another phase of the m... | 05/01/2007 |
| 7205393 | Process for the isolation and purification of a glycoprotein Avidin The present invention provides a process for the preparation of Avidin having a high purity of 98% from egg white, the said process comprising lyophilizing the homogenized egg white with buffer followed by equilibrating the lyophilized material with cation exchanger... | 04/17/2007 |
| 7186478 | Electrochemical device An electrochemical device includes an electrochemical device having an electrochemical cell located within the sealed first enclosure. The first enclosure has at least a portion that is flexible. A cavity is formed within the first enclosure so that the cavity is in... | 03/06/2007 |
| 7179939 | Sodium ferric gluconate complexes and method of manufacture thereof A process is provided for preparing a sodium ferric gluconate complex, substantially free of excipients, for providing a sodium ferric gluconate complex co-precipitated with sucrose, and for providing sodium ferric gluconate complexes in aqueous solution. ... | 02/20/2007 |
