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Patent No. 6351867

Body squeegee

A hand wearable body squeegee comprising a glove portion, a concave squeegee band, and a linear squeegee band.

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Attorney: Mohr; Judy M.


Number of patents: 95
Last date: May 08, 2012

1      
NumberTitleIssue Date
8173792Method for regulating protein function in cells using synthetic small molecules
Methods and compositions for the rapid and reversible destabilizing of specific proteins using cell-permeable, synthetic molecules are described. Stability-affecting proteins, e.g., derived from FKBP and DHFR proteins are fused to a protein of interest and the prese...
05/08/2012
8173020Method for removing contaminants from water using a membrane biofilm reactor
Apparatus and methods for water treatment are described, particularly for the simultaneous removal of nitrate, perchlorate, and other organic contaminates from contaminated water using a membrane biofilm reactor (MBfR). ...
05/08/2012
8148071Methods and compositions for isolating nucleic acid
The present invention relates to compositions and methods for isolating and purifying nucleic acid. In particular, the present invention relates to methods of isolating nucleic acid from cells for use in further analysis. ...
04/03/2012
8129510Minigene expression cassette
Methods and compositions for expressing a gene or nucleotide sequence of interest are provided. The compositions include an expression cassette that includes a synthetic enhancer, a transthyretin promoter, and a nucleotide sequence operably under the control of the ...
03/06/2012
8119166Methods of treatment using a gastric retained gabapentin dosage
A method of treatment for epilepsy and other disease states is described, which comprises delivery of gabapentin in a gastric retained dosage form. ...
02/21/2012
8109014Foot orthotic devices
A foot orthotic device is disclosed. More specifically described is an individualized foot orthotic device to correct and/or restore the ideal alignment and/or positioning of foot structures. The device is designed using a method and system that applies sequential p...
02/07/2012
8083969Thermally-responsive materials and devices comprising such materials
Devices are described that include a component comprised of a material having a structure of R1—C(O)—NX—R2, wherein each of R1 and R2 is independently a saturated alkyl having between 7-22 carbon atoms or an aryl, X ...
12/27/2011
8075501Methods for designing a foot orthotic
Disclosed are methods and systems for design of a foot orthotic, and a foot orthotic device designed in accord therewith. More specifically described is an individualized foot orthotic device to correct and/or restore the ideal alignment and/or positioning of foot s...
12/13/2011
8067532Modifications of peptide compositions to increase stability and delivery efficiency
The disclosed invention relates to methods of modifying peptide compositions to increase stability and delivery efficiency. Specifically, the disclosed invention relates to methods to increase the stability and delivery efficiency of protein kinase C (PKC) modulator...
11/29/2011
8067014Chimeric AAV capsid proteins
Recombinant adeno-associated viral (AAV) capsid proteins are provided. Methods for generating the recombinant adeno-associated viral capsid proteins and a library from which the capsids are selected are also provided. ...
11/29/2011
8043630Shell-and-core dosage form approaching zero-order drug release
Drugs are formulated as oral dosage forms for controlled release in which the release rate limiting portion is a shell surrounding the drug-containing core. The shell releases drug from the core by permitting diffusion of the drug from the core. The shell also motes...
10/25/2011
8034922Compositions and methods for modulating activity of capped small RNAs
Compositions and methods for modulating transcription by RNA polymerases are described. ...
10/11/2011
8030091Method for adding an apparent non-signal line to a rapid diagnostic assay
A test device and method for determining the presence or absence of one or more analytes in a fluid sample, the test device including a support or member bearing a mark thereon, and a matrix or member containing a capture zone. In operation, an observation area in t...
10/04/2011
7994133Isozyme-specific antagonists of protein kinase C
A method of changing or otherwise converting the biological activity of a PKC peptide agonist to a peptide antagonist is described. The method involves substituting one or more amino acid residues so as to effect a change in charge in the peptide and/or to otherwise...
08/09/2011
7985726ψεRACK peptide composition and method for protection against tissue damage due to ischemia
A method of reducing damage to cells and tissue caused by an ischemic or hypoxic event is disclosed. The method includes administering to the cell or tissue, either in vivo or ex vivo, ψεRACK peptide. The peptide can be administered before, during or after the isc...
07/26/2011
7976870Gastric retentive oral dosage form with restricted drug release in the lower gastrointestinal tract
Controlled release oral dosage forms are provided for the continuous, sustained administration of a pharmacologically active agent to the upper gastrointestinal tract of a patient in whom the fed mode as been induced. The majority of the agent is delivered, on an ex...
07/12/2011
7939493Peptide inhibitors of protein kinase C
PKC V5 isozyme-specific peptides are described. The sequences and compositions comprising the sequences are useful for treating disease states associated with the PKC isozyme from which they are respectively derived. Methods of treatment, pharmaceutical formulations...
05/10/2011
7931807Method for removing contaminants from ground water
Apparatus and methods for water treatment are described, particularly for the simultaneous removal of nitrate, perchlorate, and other organic contaminates from contaminated water using a membrane biofilm reactor (MBfR). ...
04/26/2011
7926363Systems for designing a foot orthotic
Disclosed are methods and systems for design of a foot orthotic, and a foot orthotic device designed in accord therewith. More specifically described is an individualized foot orthotic device to correct and/or restore the ideal alignment and/or positioning of foot s...
04/19/2011
7914480Transdermal delivery device
A dermal, transdermal, mucosal or transmucosal delivery device includes a backing layer overlying an ingredient containing reservoir, and having a microprotrusion array attached thereto, a cover for the reservoir having at least one opening therethrough, an adhesive...
03/29/2011
7871568Rapid test apparatus
Provided herein are methods and devices for rapid testing of solid, semi-solid, or liquid specimens, such as stool, blood, urine, saliva, or swab specimens of the cervix, urethra, nostril, and throat, and for environmental testing. ...
01/18/2011
7833984Peptide inhibitors of protein kinase C
PKC V5 isozyme-specific peptides are described. The sequences and compositions comprising the sequences are useful for treating disease states associated with the PKC isozyme from which they are respectively derived. Methods of treatment, pharmaceutical formulations...
11/16/2010
7815801Removal of selenium in contaminated wastewater streams
Compositions and methods for the removal of selenium species from water containing high-salt concentrations and/or petroleum contaminants are described. The compositions and methods use a selenium-reducing microorganism adapted to adverse environments. ...
10/19/2010
7807202Compositions for treatment of viral-induced skin lesions and methods of using same
A composition and method for treatment of viral-induced skin lesions, such as warts, are described. The composition is comprised of tea tree oil and/or derivatives from tea tree oil and one or more minerals, such as iodide and/or selenium. The composition is used to...
10/05/2010
7803775Protein kinase C peptides for use in withdrawal
A method for managing withdrawal from an addictive substance is described. The method involves administering one or more peptides having specific activity for the ε and/or γ isozyme of protein kinase C (PKC). The peptide(s) can be administered prior to, concurrent...
09/28/2010
7794657Phase change sensor
A device is disclosed which is a highly sensitive and selective sensor. The device is comprised of a sensor material secured into a fixed position on substrate, a deformable arm and a signaling component which creates a detectable signal in response to movement of t...
09/14/2010
7794656Device for handling and analysis of a biological sample
An apparatus for detection of an analyte of interest in a solid, semi-solid, or liquid biological sample, using a lateral flow assay test strip, is described. The apparatus minimizes sample handling and manipulation upon introduction of the sample into a sample-rece...
09/14/2010
7745412Isozyme-specific antagonists of protein kinase C
A method of changing or otherwise converting the biological activity of a PKC peptide agonist to a peptide antagonist is described. The method involves substituting one or more amino acid residues so as to effect a change in charge in the peptide and/or to otherwise...
06/29/2010
7741290Method of preventing progression of hypertension-induced heart failure with PKC peptides
Methods are described for slowing or inhibiting the progression of heart failure in a mammalian subject suffering from chronic hypertension. The methods involve administering an εPKC, β1PKC, or βIIPKC peptide inhibitor, examples of which are provided. ...
06/22/2010
7736667Shell-and-core dosage form approaching zero-order drug release
Drugs are formulated as oral dosage forms for controlled release in which the release rate limiting portion is a shell surrounding the drug-containing core. The shell releases drug from the core by permitting diffusion of the drug from the core. The shell also promo...
06/15/2010
7731989Gastric retained gabapentin dosage form
A method of treatment for epilepsy and other disease states is described, which comprises the delivery of gabapentin in a gastric retained dosage form. ...
06/08/2010
7695710Antitumor and antiviral combination therapies using low-toxicity, long-circulating human interferon-alpha analogs
Interferon-alpha (IFNα) analog proteins modified by chemical attachment of at least one hydrophilic polymer moiety, such as polyethylene glycol chain, are described for use in combination therapies with antiviral and/or antitumor agents. In one embodiment, the IFNÎ...
04/13/2010
7691644Devices for the detection of multiple analytes in a sample
The present invention relates generally to an assay for detecting and differentiating multiple analytes, if present, in a single fluid sample, including devices and methods therefore. ...
04/06/2010
7662370Low-toxicity, long-circulating human interferon-alpha PEGylated mutants
Interferon-alpha (IFNα) analog proteins modified by chemical attachment of at least one hydrophilic polymer moiety, such as polyethylene glycol chain, are described. In one embodiment, the IFNα analog protein has an amino acid sequence that differs from a native h...
02/16/2010
7638915Modular magneto-mechanical device
An electromechanical device has a rotor, a stator, and a module that at least partially houses the rotor. During normal operation of the electromechanical device, the stator is positioned external to and separate from the module. ...
12/29/2009
D606664Assay device and housing combined
12/22/2009
7632687Hybrid phase lateral flow assay
The invention relates to devices for performing single step assays for the determination of the presence or absence of an analyte in a liquid sample, and methods of determining the presence or absence of such analytes using such devices. Devices disclosed comprise a...
12/15/2009
7618537Membrane biofilm reactor method for reducing the concentration of oxidized contaminants in ground water
Apparatus and methods for water treatment are described, particularly for the simultaneous removal of nitrate, perchlorate, and other organic contaminates from contaminated water using a membrane biofilm reactor (MBfR). ...
11/17/2009
7612112Methods of treatment using a gastric retained gabapentin dosage
A method of treatment for epilepsy and other disease states is described, which comprises the delivery of gabapentin in a gastric retained dosage form. ...
11/03/2009
7588772AAV capsid library and AAV capsid proteins
Recombinant adeno-associated viral (AAV) capsid proteins are provided. Methods for generating the recombinant adeno-associated viral capsid proteins and a library from which the capsids are selected are also provided. ...
09/15/2009
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