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| Number | Title | Issue Date |
| 8153134 | Anti-MDL-1 antibodies Antibodies to human MDL-1 are provided, as well as uses thereof, e.g., in treatment of immune disorders, in particular, infectious diseases and sepsis. ... | 04/10/2012 |
| 8148507 | Nucleic acid encoding TNFx protein Nucleic acids encoding mammalian, e.g., primate or rodent, genes, purified proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are provided. | 04/03/2012 |
| 7893211 | Mammalian genes; related reagents and methods Nucleic acids encoding mammalian, e.g., primate or rodent, genes, purified proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are provided. | 02/22/2011 |
| 7812126 | DIRS1 polypeptides Nucleic acids encoding mammalian, e.g., primate or rodent receptors, purified receptor proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are ... | 10/12/2010 |
| 7807160 | Engineered anti-IL-23 antibodies Engineered antibodies to human IL-23p19 are provided, as well as uses thereof, e.g. in treatment of inflammatory, autoimmune, and proliferative disorders. ... | 10/05/2010 |
| 7427668 | Antibodies binding the TNF related protein, TNF-Y Nucleic acids encoding mammalian, e.g., primate or rodent, genes, purified proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are provided. | 09/23/2008 |
| 7390481 | Mammalian cytokine complexes Purified genes encoding cytokine from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding this molecule are provided. Methods of using said reagents and diagnostic kits are also provided. ... | 06/24/2008 |
| 7342103 | DIRS1 antibodies The present invention provides nucleic acids encoding mammalian, e.g., primate or rodent receptors, purified receptor proteins and fragments thereof, and antibodies against these receptor proteins. Methods of using these compositions for both diagnostic and therapeu... | 03/11/2008 |
| 7332156 | Methods of treating wounds using IL-23 Provided are methods of treatment for skin disorders. In particular, treatment, the skin disorders are generally inflammatory skin disorders, including improper wound healing. Provided are methods of using of a cytokine molecule. ... | 02/19/2008 |
| 7332574 | MDL-1 polypeptides The purification and isolation of various genes which encode mammalian cell surface polypeptides. Nucleic acids, proteins, antibodies, and other reagents useful in modulating development of cells, e.g., lymphoid and myeloid, are provided, along with methods for thei... | 02/19/2008 |
| 7319140 | Binding compounds to DAP12 proteins The purification and isolation of various genes which encode mammalian cell surface polypeptides. Nucleic acids, proteins, antibodies, and other reagents useful in modulating development of cells, e.g., lymphoid and myeloid, are provided, along with methods for thei... | 01/15/2008 |
| 7282204 | Uses of IL-23 agonists and antagonists; related reagents Provided are methods of treatment for tumors. In particular, methods are provided for modulating activity of a cytokine molecule and its receptor. ... | 10/16/2007 |
| 7241438 | AK155 polypeptides Purified genes encoding a cytokine from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding this molecule are provided. Methods of using said reagents and diagnostic kits are also provided. ... | 07/10/2007 |
| 7122340 | Regulatory T cells; methods Methods for increasing yields of regulatory T cells, useful, e.g., in transplantation contexts. Use of antigen presenting cells and anti-CD28 are also described. ... | 10/17/2006 |
| 7108850 | Polypeptides of an IL-1-like cytokine Nucleic acids encoding mammalian, e.g., primate, IL-1ζ, purified IL-1ζ polypeptides and fragments thereof. Binding proteins, e.g., antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic ... | 09/19/2006 |
| 7071308 | Cytokine receptor Nucleic acids encoding mammalian cytokine receptor, e.g., for cytokine IL-B50, purified proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are... | 07/04/2006 |
| 7005501 | Purified mammalian cytokines; related reagents and methods CTLA-8 related antigens from mammals, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding said antigens. Methods of using said reagents and diagnostic kits are also provided. ... | 02/28/2006 |
| 6953843 | Antibodies and fragments thereof to MDL-1 protein The purification and isolation of various genes which encode mammalian cell surface polypeptides. Nucleic acids, proteins, antibodies, and other reagents useful in modulating development of cells, e.g., lymphoid and myeloid, are provided, along with methods for thei... | 10/11/2005 |
| 6913924 | Population of interferon producing cells Dendritic cell subsets, and various methods of making and using same are provided. In particular, methods for making a defined subset of dendritic cells are provided. ... | 07/05/2005 |
| 6890734 | Nucleic acids encoding a cytokine receptor complex Nucleic acids encoding mammalian cytokine receptor, e.g., for cytokine IL-B50, purified proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are... | 05/10/2005 |
| 6843987 | Mammalian cytokines; receptors; related reagents and methods Nucleic acids encoding mammalian, e.g., rodent, IL-1δ, IL-1ε, purified IL-1δ and IL-1ε proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities ... | 01/18/2005 |
| 6835825 | Method for detecting IL-B30 polynucleotides The invention provided herein relates generally to purified genes encoding mammalian cytokines as well as reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding these molecules. In particular, the novel cytokine, IL-B30... | 12/28/2004 |
| 6800460 | Mammalian cytokine complexes Purified genes encoding cytokine from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding this molecule are provided. Methods of using said reagents and diagnostic kits are also provided. ... | 10/05/2004 |
| 6797813 | AK155 antibodies and binding fragments thereof Purified genes encoding a cytokine from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding this molecule are provided. Methods of using these reagents and diagnostic kits are also provided. ... | 09/28/2004 |
| 6756481 | IL-23 receptor binding compositions Nucleic acids encoding mammalian, e.g., primate, receptors, purified receptor proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are described... | 06/29/2004 |
| 6737252 | 7 transmembrane receptor family member BLRX Novel chemokines and 7 transmembrane receptors from mammals, reagents related thereto, including purified proteins, specific antibodies, and nucleic acids encoding the chemokines and receptors are disclosed. Methods of using the chemokines, receptors, reagents and d... | 05/18/2004 |
| 6723520 | Antibodies that bind chemokine teck Novel chemokines from mammals, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding said chemokines. Chemokine receptors are also provided. Methods of using said reagents and diagnostic kits are also provided. ... | 04/20/2004 |
| 6706870 | Nucleic acids encoding CTLA-8; and related reagents CTLA-8 antigen from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding said antigen. Methods of using said reagents and diagnostic kits are also provided. ... | 03/16/2004 |
| 6680380 | Nucleic acids encoding mammalian interleukin-1.zeta., related reagents and methods Nucleic acids encoding mammalian, e.g., primate, IL-1.zeta., purified IL-1.zeta. polypeptides and fragments thereof. Binding proteins, e.g., antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnost... | 01/20/2004 |
| 6660523 | Dendritic cells; methods Dendritic cell subsets, and various methods of making and using same are provided. In particular, methods for making a defined subset of dendritic cells are provided.... | 12/09/2003 |
| 6335172 | Cloned tetrodotoxin-sensitive sodium channel -subunit and a splice variant thereof DNA encoding for a voltage-gated, TTX-sensitive sodium channel is isolated. Also disclosed are polypeptide products of recombinant expression of these DNA sequences, expression vectors comprising the DNA sequences, and host cells transformed with these ex... | 01/01/2002 |
| 6274312 | Intracellular regulatory molecules; related reagents Purified genes encoding intracellular regulatory molecules from a human, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding these molecules are provided. Methods of using said reagents and diagnostic kits... | 08/14/2001 |
| 6245329 | Method of inducing calcium flux in cells using mammalian thymokine protein Nucleic acids encoding a thymokine from a mammal, reagents related thereto, including specific antibodies, and purified proteins are described. Methods of using said reagents and related diagnostic kits are also provided.... | 06/12/2001 |
| 5998165 | Polynucleotides encoding a protein associated with pancreatic cancer The present invention provides polynucleotides and related reagents which are associated with pancreatic and other cancers. These polynucleotides are designated PANC1A.... | 12/07/1999 |
| 5981221 | Histone fusion protein The present invention provides a human histone fusion protein (HFP) and polynucleotides which identify and encode HFP. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. In addition, the invention also provid... | 11/09/1999 |
| 5977320 | Antibody to novel human phosphorylase kinase gamma subunit The present invention provides a novel human phosphorylase kinase gamma subunit (HPHKG) and the polynucleotide which identifies and encodes HPHKG. The invention provides for expression vectors and host cells comprising the nucleic acid sequence encoding H... | 11/02/1999 |
| 5965423 | Human lysophospholipase The invention provides a human lysophospholipase (NHLP) and polynucleotides which identify and encode NHLP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating... | 10/12/1999 |
| 5962646 | ATP synthase Fo subunit The present invention provides a human ATP synthase d subunit (ASYSD) and polynucleotides which encode ASYSD. The invention also provides expression vectors, host cells, agonists, antisense molecules, antibodies, or antagonists. The invention also provide... | 10/05/1999 |
| 5955284 | Assay method to detect serpin derived from human hypothalamus The present invention provides nucleotide and amino acid sequences that identify and encode a novel serpin (CAPE) expressed in human hypothalamus. The present invention also provides for antisense molecules to the nucleotide sequences which encode CAPE, e... | 09/21/1999 |
| 5952479 | Human arsenite-resistance protein The invention provides a human arsenite-resistance protein (NITE) and polynucleotides which identify and encode NITE. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods fo... | 09/14/1999 |
