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A self defense weapon formed as a memo pad and which is easily held by a person's fingers, therefore making it possible to provide protection from a mugger and also to quickly and easily write a record or a message without failure of missing or forgetting significant information under a stressful situation.
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| Number | Title | Issue Date |
| 8183361 | Oligonucleotide-containing pharmacological compositions and their use The present invention relates to methods and compositions containing oligonucleotides suitable for administration to humans and other mammals. ... | 05/22/2012 |
| 8182816 | Methods of treating cancer Disclosed are methods of treating subjects having cancers including administering an effective amount of an early activation molecule agonist, antagonist or depletor, to the subject. Human monoclonal antibodies specific to the early activation molecules, and methods... | 05/22/2012 |
| 8173808 | Substituted naphthalenyl-pyrimidine compounds The present invention relates to substituted naphthalenyl-pyrimidine compounds and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing substituted naphthalenyl-pyrimidine compounds and methods of trea... | 05/08/2012 |
| 8173624 | Methods of using substituted tetracycline compounds to modulate RNA A method for modulating RNA with tetracycline compounds is described. ... | 05/08/2012 |
| 8173372 | Methods of donor specific crossmatching The detection of endothelial cell antibodies has been proven clinically important for successful organ transplantation. Disclosed are methods of isolating Tie-2+ and CD34− precursor endothelial cells for use in donor-specific crossmatching. | 05/08/2012 |
| 8171229 | Wait-free parallel data cache A system and method for managing a data cache in a central processing unit (CPU) of a database system. A method executed by a system includes the processing steps of adding an ID of a page p into a page holder queue of the data cache, executing a memory barrier stor... | 05/01/2012 |
| 8168810 | 7-phenyl-substituted tetracycline compounds 7-phenyl-substituted tetracycline compounds, methods of treating tetracycline responsive states, and pharmaceutical compositions containing the 7-phenyl-substituted tetracycline compounds are described. ... | 05/01/2012 |
| 8168393 | Compositions and methods for diagnosing tumors using LEDGF/p75 The invention provides methods for diagnosing tumors in mammals using a reagent that bind to LEDGF/p75 or to a nucleic acid encoding LEDGF/p75. For example, the tumor may be located in the CNS, the prostate, the skin, the bone marrow, or the gut of the mammal. Also ... | 05/01/2012 |
| 8168218 | Delayed release tablet with defined core geometry A press-coated tablet comprising a core containing an drug substance, and a coating, the core being disposed within the coating such that the coating has a first thickness about an axis A-B and a thickness about an orthogonal axis X-Y, such that the coating about th... | 05/01/2012 |
| 8160897 | Satori integrated health and financial benefits system and method A shared medical savings system and method are provided that allow a patient to participate in the savings generated by selecting to have a medical procedure performed overseas. The system has one or more computing devices, a link that is capable of connecting the o... | 04/17/2012 |
| 8158359 | Methods of amplifying and sequencing nucleic acids An apparatus and method for performing rapid DNA sequencing, such as genomic sequencing, is provided herein. The method includes the steps of preparing a sample DNA for genomic sequencing, amplifying the prepared DNA in a representative manner, and performing multip... | 04/17/2012 |
| 8158122 | Mixed cell populations for tissue repair and separation technique for cell processing The present invention provides a fluid exchange cell culture technique and tissue repair cells (TRCs) made by these methods, as well as methods using these cells. The method includes a new wash step which increases the tissue repair properties of the TRCs of the inv... | 04/17/2012 |
| 8156473 | Model oriented debugging A system and method for debugging a business application that has been generated according to a model are disclosed. A system includes a debugger that generates a model-oriented debugging view based on a model-oriented development environment that generates the busi... | 04/10/2012 |
| 8156469 | Single composition of pattern modules A computer-implemented method, system, and computer program product for generating an application based on a selection of one or more application patterns. A model of an operation of the application is generated. A design time application component to provide conten... | 04/10/2012 |
| 8153644 | Diacylglycerol acyltransferase inhibitors Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositi... | 04/10/2012 |
| 8153402 | Emulsion compositions An emulsion is useful in allowing a wide variety of gene products to be expressed via eukaryotic in vitro expression. The emulsion comprises a silicone based surfactant, a hydrophobic phase and a hydrophilic phase; wherein the hydrophilic phase comprises a plurality... | 04/10/2012 |
| 8152811 | Positioning device for a prosthesis device and system therefore A positioning device for placing a prosthesis device in a spinal column of a living mammal, the device including at least one holding means for cooperation with the prosthesis device and for guiding thereof during positioning. The positioning device may also include... | 04/10/2012 |
| 8150744 | Revenue assurance analytics A system and method of revenue assurance for a service activity are presented. Multiple data feeds are received by a revenue assurance analytic system, where each data feed contains the same logical component of the service activity. The multiple data feeds are proc... | 04/03/2012 |
| 8148512 | Methods for detection and quantification of analytes in complex mixtures The invention provides a diverse population of uniquely labeled probes, containing target specific nucleic acid probes each attached to a unique label bound to a nucleic acid. Also provided is a method of detecting a nucleic acid analyte. The method consists of (a) ... | 04/03/2012 |
| 8147446 | Detachable portable infusion device A portable therapeutic apparatus and a method for controlling the apparatus are provided. In one aspect the apparatus and the method can be implemented using a patch unit (100, 200) removably attachable to a cradle unit (20), said cradle unit removably... | 04/03/2012 |
| 8146103 | Aggregation and evaluation of monitoring events from heterogeneous systems A system and method for monitoring activity of heterogeneous systems within a business application landscape are disclosed. An object state change is detected in an object instance of one or more systems of the business application landscape. Each object state chang... | 03/27/2012 |
| 8141740 | Portable container A portable container system having a container body, including an external housing of a durable material and an internal liner constructed of a crystalline ceramic material is provided. A portion of the internal liner extends above the external housing through an op... | 03/27/2012 |
| 8129128 | Immunoassay reagent compositions for diagnosing multiple sclerosis This application is related to immunoassay reagent compositions comprising a glycan reagent for diagnosing multiple sclerosis. ... | 03/06/2012 |
| 8127299 | Landscape reorganization algorithm for dynamic load balancing A method and system for reorganizing a distributed computing landscape for dynamic load balancing is presented. A method includes the steps of collecting information about resource usage by a plurality of hosts in a distributed computing system, and generating a tar... | 02/28/2012 |
| 8127245 | Multi-dimensional systems and controls An information access system and method are disclosed. A system includes a user input device and a graphical user interface responsive to commands from the user input device. A plurality of graphical structures is displayed in the graphical user interface. Each grap... | 02/28/2012 |
| 8126961 | Integration of client and server development environments Methods and apparatus, including computer program products, related to integration of client and server development environments. A message may be caused to be sent to a server development environment engine where the message characterizes an action mapped from a cl... | 02/28/2012 |
| 8124766 | Inhibitors of diacylglycerol acyltransferase Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositi... | 02/28/2012 |
| 8122003 | Request-based knowledge acquisition One implementation provides a method for acquiring knowledge from multiple knowledge bases in a knowledge repository. The method includes identifying first and second knowledge bases within the knowledge repository by analyzing a search request received from a clien... | 02/21/2012 |
| 8121962 | Automated entity identification for efficient profiling in an event probability prediction system A computer-implemented method and system for automated entity identification for efficient profiling in an event probability prediction system. A first subset of entities belonging to one or more entity classes is defined. At least one historical profile is construc... | 02/21/2012 |
| 8121329 | Expandable speaker assemblies for portable media devices Speaker assemblies and cradles for portable media players are disclosed herein. Speaker assemblies can include means for contracting and expanding the speakers to facilitate viewing and listening to a PMP in multiple orientations. Preferred means for contracting and... | 02/21/2012 |
| 8119622 | 7-phenyl-substituted tetracycline compounds 7-phenyl-substituted tetracycline compounds which are substantially free of positional isomers, methods of treating tetracycline responsive states, and pharmaceutical compositions containing the 7-phenyl-substituted tetracycline compounds are described. 7-substitute... | 02/21/2012 |
| 8119405 | Methods of inducing regulated pancreatic hormone production in non-pancreatic islet tissues Disclosed are methods and pharmaceutical compositions for inducing pancreatic hormone production. ... | 02/21/2012 |
| 8119357 | Method for analyzing a glycomolecule The invention relates generally the structural analysis of glycomolecule-containing macromolecules, such as those that occur either attached to proteins (proteoglycans, glycoproteins), lipids, or as free saccharides. ... | 02/21/2012 |
| 8115011 | Diacylglycerol acyltransferase inhibitors Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositi... | 02/14/2012 |
| 8114831 | Guanylate cyclase receptor agonists for the treatment of tissue inflammation and carcinogenesis A method of treatment of inflamed, pre-cancerous or cancerous tissue or polyps in a mammalian subject is disclosed. The treatment involves administration of a composition of at least one peptide agonist of a guanylate cyclase receptor and/or other small molecules th... | 02/14/2012 |
| 8114402 | Compositions and methods for the therapy and diagnosis of influenza The present invention provides novel human anti-influenza antibodies and related compositions and methods. These antibodies are used in the diagnosis and treatment of influenza infection. ... | 02/14/2012 |
| 8112909 | Sole with reinforcement structure This invention relates to a shoe sole that solves the problems on weight saving in shoes, prevention of distortion, improvement in the fitting property and prevention of upthrust simultaneously. The reinforcing member 3 for reinforcing a part of the midsole | 02/14/2012 |
| D654124 | Portable travel exercise apparatus | 02/14/2012 |
| D653884 | Aircraft seat | 02/14/2012 |
| D653883 | Aircraft seating configuration | 02/14/2012 |
