Decorative Jeweled Wheel Cover
An improved wheel is provided wherein decorative items such as gem stones are embedded in either the wheel surface, a special mounting section attached to the wheel surface, or to a spoke strap that wraps around each spoke and positions embedded gem stones on the outside surface of the spoke.
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| Number | Title | Issue Date |
| 8163921 | Hepatitis C virus inhibitors Hepatitis C virus inhibitors having the general formula are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed. ... | 04/24/2012 |
| 8147818 | Hepatitis C virus inhibitors The present disclosure relates to compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infec... | 04/03/2012 |
| 8143414 | Hepatitis C virus inhibitors This disclosure concerns novel compounds of Formula (I) or Formula (II) as defined in the specification and compositions comprising such novel compounds. These compounds are useful antiviral agents, especially in inhibiting the function of the NS5A protein encoded b... | 03/27/2012 |
| 8143301 | Hepatitis C virus inhibitors The present disclosure relates to compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infec... | 03/27/2012 |
| 8143288 | Inhibitors of HCV replication Compounds having the structure of formula I are described. The compounds can inhibit hepatitis C virus (HCV) replication, and in particular can inhibit the function of the HCV NS5A protein. ... | 03/27/2012 |
| 8138215 | Hepatitis C virus inhibitors The present disclosure relates to compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infec... | 03/20/2012 |
| 8093276 | Alpha-(N-sulfonamido)acetamide compound as an inhibitor of beta amyloid peptide production The present invention provides a method for the treatment of head trauma, traumatic brain injury, and/or dementia pugilistica comprising administering a therapeutically effective amount of (2R)-2-[[(4-chlorophenyl)sulfonyl][[2-fluoro-4-(1,2,4-oxadiazol-3-yl)phenyl]m... | 01/10/2012 |
| 8093243 | Hepatitis C virus inhibitors The present disclosure relates to compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infec... | 01/10/2012 |
| 8084477 | Alpha-(N-sulfonamido)acetamide compound as an inhibitor of beta amyloid peptide production The present invention provides a novel alpha-(N-sulfonamido)acetamide compound, its pharmaceutical composition, processes thereof and a method for the treatment of Alzheimer's disease and other conditions associated with β-amyloid peptide. ... | 12/27/2011 |
| 8044087 | Hepatitis C virus inhibitors Hepatitis C virus inhibitors having the general formula are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed. ... | 10/25/2011 |
| 8044077 | Alpha-(N-sulfonamido)acetamide compounds incorporating deuterium as inhibitors of beta amyloid peptide production The present disclosure provides novel deuterated alpha-(N-sulfonamido)acetamide compounds, their pharmaceutical composition, processes thereof and a method for the treatment of Alzheimer's disease, head trauma, traumatic brain injury, and/or dementia pugilistica and... | 10/25/2011 |
| 8044023 | Hepatitis C virus inhibitors Hepatitis C virus inhibitors having the general formula are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed. ... | 10/25/2011 |
| 8003604 | Hepatitis C virus inhibitors Macrocyclic peptides having the general formula: are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed. ... | 08/23/2011 |
| 7977362 | Alpha-(N-benzenesulfonamido)cycloalkyl derivatives Disclosed are compounds, pharmaceutical compositions containing the compounds, methods for using the compounds and processes for making the compounds. More specifically, the disclosure relates to alpha-(N-benzenesulfonamido)cycloalkyl compounds that may inhibit one ... | 07/12/2011 |
| 7964560 | Hepatitis C virus inhibitors Hepatitis C virus inhibitors having the general formula are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed. ... | 06/21/2011 |
| 7935670 | Hepatitis C virus inhibitors Hepatitis C virus inhibitors having the general formula are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed. ... | 05/03/2011 |
| 7915291 | Hepatitis C virus inhibitors Hepatitis C virus inhibitors are disclosed having the general formula: wherein R1, R2, R3, R′, B, Y and X are described in the description. Compositions comprising... | 03/29/2011 |
| 7906655 | Hepatitis C virus inhibitors The present disclosure relates to compounds, compositions and methods for the treatment of Hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infec... | 03/15/2011 |
| 7888464 | Hepatitis C virus inhibitors Hepatitis C virus inhibitors having the general formula are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed. ... | 02/15/2011 |
| 7786122 | α-(N-sulfonamido)acetamide derivatives as β-amyloid inhibitors There is provided a series of novel α-(N-sulfonamido)acetamide compounds of the Formula (I) wherein R, R1, R2 and R3 are defined herein, which are inhibitors of β-amyloid peptide (β-AP) p... | 08/31/2010 |
| 7772183 | Hepatitis C virus inhibitors Hepatitis C virus inhibitors having the general formula are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed. ... | 08/10/2010 |
| 7772180 | Hepatitis C virus inhibitors Hepatitis C virus inhibitors having the general formula are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed. ... | 08/10/2010 |
| 7763584 | Hepatitis C virus inhibitors Macrocyclic peptides having the general formula: are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed. ... | 07/27/2010 |
| 7759495 | Hepatitis C virus inhibitors The present disclosure relates to compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infec... | 07/20/2010 |
| 7745636 | Hepatitis C virus inhibitors The present disclosure relates to compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infec... | 06/29/2010 |
| 7741347 | Hepatitis C virus inhibitors The present disclosure relates to compounds, compositions and methods for the treatment of Hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infec... | 06/22/2010 |
| 7741281 | Hepatitis C virus inhibitors Macrocyclic peptides are disclosed having the general formula: wherein R′, R3, R3′, R4, R6, X, Q, and W are described. Compositions comprising the com... | 06/22/2010 |
| 7728027 | Process for synthesizing compounds useful for treating hepatitis C The present disclosure generally relates to a process for synthesizing methyl ((1S)-1-(((2S)-2-(5-(4′-(2-((2S)-1-((2S)-2-((methoxycarbonyl)amino)-3-methylbutanoyl)-2-pyrrolidinyl)-1H-imidazol-5-yl)-4-biphenylyl)-1H-imidazol-2-yl)-1-pyrrolidinyl)carbonyl)-2-methylp... | 06/01/2010 |
| 7704992 | Hepatitis C virus inhibitors The present disclosure relates to compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infec... | 04/27/2010 |
| 7659270 | Hepatitis C virus inhibitors The present disclosure relates to compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infec... | 02/09/2010 |
| 7655647 | Substituted lactams as inhibitors of Aβ protein production This invention relates to novel lactams of Formula (I): having drug and bio-affecting properties, their pharmaceutical compositions and methods of use. These novel compounds inhibit the processing of amyloid precursor prote... | 02/02/2010 |
| 7601686 | Hepatitis C virus inhibitors The present disclosure relates to tripeptide compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment o... | 10/13/2009 |
| 7592336 | Hepatitis C virus inhibitors Hepatitis C virus inhibitors having the general formula are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed. ... | 09/22/2009 |
| 7528249 | Cyclic malonamides as inhibitors of aβ protein production This invention relates to novel cyclic malonamides having the formula (I): to their pharmaceutical compositions and to their methods of use. These novel compounds inhibit the processing of amyloid precursor protein and, mor... | 05/05/2009 |
| 7423033 | Hydroxyalkanoylaminolactams and related structures as inhibitors of aβ protein production This invention relates to novel lactams having the formula (I): to their pharmaceutical compositions and to their methods of use. These novel compounds inhibit the processing of amyloid precursor protein and, more specifica... | 09/09/2008 |
| 7507815 | Succinoylamino lactams as inhibitors of a-β protein production This invention relates to novel lactams having drug and bio-affecting properties, their pharmaceutical compositions and methods of use. These novel compounds inhibit the processing of amyloid precursor protein and, more specifically, inhibit the production of Aβ-pe... | 03/24/2009 |
| 7498324 | Substituted lactams as inhibitors of Aβ protein production This invention relates to novel lactams of Formula (I): having drug and bio-affecting properties, their pharmaceutical compositions and methods of use. These novel compounds inhibit the processing of amyloid precursor prote... | 03/03/2009 |
| 7456172 | Succinoylamino benzodiazepines as inhibitors of Aβ protein production This invention relates to novel lactams having the formula (I): to their pharmaceutical compositions and to their methods of use. These novel compounds inhibit the processing of amyloid precursor protein and, more specifica... | 11/25/2008 |
| 7449479 | Hepatitis C virus inhibitors Hepatitis C virus inhibitors are disclosed having the general formula: wherein R1, R2, R3, R′, B, Y and X are described in the description. Compositions comprising the compounds an... | 11/11/2008 |