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Attorney: Miles & Stockbridge, Clarke; Dennis P.


Number of patents: 37
Last date: April 08, 2003

NumberTitleIssue Date
6546279Computer controlled guidance of a biopsy needle
A computer controlled system for guiding the needle device, such as a biopsy needle, by reference to a single mode medical imaging system employing any one of computed tomography imaging (CTI) equipment, magnetic resonance imaging equipment (MRI), fluoros...
04/08/2003
6532463Web page accessing of data bases and mainframes
A method of providing Web access to data using dynamic generation of Web pages by a mainframe computer connected to a Web server. The mainframe computer has legacy programs, legacy data, and legacy subroutines on it (Legacy means existing information syst...
03/11/2003
6494652Blind rivet and method of making the same
Disclosed is a self plugging blind rivet for securing together apertured members, the rivet comprising a tubular shell having a tail end face at one end and a preformed radially enlarged bead at the other end, and a stem that extends through the shell and...
12/17/2002
6472426Sterically hindered tetraamines and method for their production
Polyamines having the formula: ##STR1## wherein R1 and R2 are alkyl, aralkyl or aryl having up to 10 carbon atoms; and a and b may be the same or different and are integers from 1 to 8; or a salt thereof with a pharmaceutically accep...
10/29/2002
6464970Method and composition for preventing surgical adhesions
An improved method and composition for preventing adhesions during surgery. Tissue surfaces and surgical articles involved in the surgery are coated with a solution of a hydrophilic, polymeric material prior to manipulation of the tissue during surgery. T...
10/15/2002
6458795Method and composition for treatment of irritable bowel disease
A method and composition for treating irritable bowel syndrome in a subject in need of such treatment, utilizing an amount of a polyamine having the formula: R--NH--(CH2)a --NH--(CH2)b H--(CH2)c...
10/01/2002
6455591Polyamines and anti-diarrheal and gastrointestinal anti-spasmodic pharmaceutical compositions and methods of treatment
Anti-diarrheal, anti-secretory, nitric oxide agonist, nitric oxide synthase activating or gastrointestinal anti-spasmodic compounds of the formula: ##STR1## R1 --N1 H--(CH2)3 --N2 H--(C2)
09/24/2002
6449336Multi-source intensity-modulated radiation beam delivery system and method
A technique for Intensity-modulated radiation therapy (IMRT), an advanced form of external beam irradiation that is commonly referred as three-dimensional conformal radiation therapy (3DCRT), uses an array of radiation sources disposed within cells of a t...
09/10/2002
6399662Method and composition for the treatment of diarrhea and gastrointestinal spasms
Anti-diarrheal and/or gastrointestinal anti-spasmodic pharmaceutical compositions containing [A] a polyamine of the formula: R1 --N1 (R2)--(CH2)x--N2 H--Q--N3 H--(CH2)y--N4...
06/04/2002
6390982Ultrasonic guidance of target structures for medical procedures
A system comprising a combination of an ultrasound probe and both passive and active infrared tracking systems. The combined system enables a real time image display of the entire region of interest without probe movement; real time tracking of the target...
05/21/2002
6387379Biofunctional surface modified ocular implants, surgical instruments, medical devices, prostheses, contact lenses and the like
A method for modifying the surface of a material adapted for contact with tissue of a human or non-human animal to impart biofunctional, bioactive or biomimetic properties to the surface comprising: (a) exposing the surface to a solution comprising (1) an ethy...
05/14/2002
6346124Autonomous boundary detection system for echocardiographic images
A method for generating a synthesis echocardiographic image comprises first obtaining, for a plurality of pathologically similar reference hearts, a reference echocardiographic image of each reference heart at end-systole and at end-diastole. Next, the co...
02/12/2002
6318037Window frame
A Window frame including two frame members (1, 2) adapted to mutual locking engagement, between which members a window pane (50) can be secured. One frame member (1) includes a tubular portion (5), into which a screw (3) may, be driven through the second ...
11/20/2001
6297287Anti-arrhythmic composition and methods of treatment
Pharmaceutical compositions for the treatment of cardiac arrhythmia comprising an effective anti-arrhythmic amount of at least one compound in association with a pharmaceutically acceptable, substantially non-toxic carrier or excipient, the compound havin...
10/02/2001
6274630Method of inhibiting biosynthesis of EIf5A
A method and pharmaceutical composition for inhibiting or preventing the intracellular biosynthesis of EIf5A by the administration to a human or non-human mammal in need thereof an amount of a polyamine analogue or salt thereof sufficient to deplete the s...
08/14/2001
6262125Sterically hindered tetraamines and method for their production
Polyamines having the formula: ##STR1## wherein R1 and R2 are alkyl, aralkyl or aryl having up to 10 carbon atoms; and a and b may be the same or different and are integers from 1 to 8; or a salt thereof with a pharmaceutically acceptable...
07/17/2001
6235794Biologically active spermidine analogues, pharmaceutical compositions and methods of treatment
Polyamines having the formula: ##STR1## or a salt thereof with a pharmaceutically acceptable acid wherein: R1 -R5 may be the same or different and are alkyl, aryl, aryl alkyl, cycloalkyl or hydrogen; at least one of R1 and...
05/22/2001
6217706Method of de-inking paper and other cellulosic materials
A method of de-inking cellulosic fibrous materials comprising: a. admixing an alkaline reagent selected from the group consisting of ammonium hydroxide and hydrogen peroxide and mixtures thereof with an aqueous suspension of inked cellulosic fibrous material s...
04/17/2001
6190606Solid amalgamating compositions for the preparation of dental amalgams, amalgam forming compositions containing them, methods for producing dental amalgams with them and dental amalgams produced thereby
The present invention concerns totally solid amalgamating compositions particularly useful in the preparation of dental amalgams for filling cavities and similar dental applications, comprising one or more solid amalgamating alloys, metals and/or intermet...
02/20/2001
6167072Modulated cap thin p-clad semiconductor laser
A semiconductor laser structure for use having a laser substructure so constructed and arranged to have an active region in close proximity to the top surface region and separated therefrom by a separation region, the separation region having a lower refr...
12/26/2000
6161537Transtracheal energy application and sensing system for intubation: method and apparatus
An intubation scope assembly adapted to facilitate the positioning of an endotracheal tube in a patient comprising an electromagnetic or sound energy source which enters the vocal cords exteriorly of the neck of the patient with energy having a direction,...
12/19/2000
6160022Chemical resection of pancreas
A method of chemically resecting the exocrine portion of the pancreas of a patient in need thereof comprising administering to the patient an amount of a hydroxy polyamine or a salt thereof with a pharmaceutically acceptable acid sufficient to resect the ...
12/12/2000
6159983Method and composition for treatment of inflammatory bowel disease
A composition in unit dosage form for the inhibition, prevention or treatment of inflammatory bowel disease comprising an effective amount of a compound having the formula: ##STR1## and a pharmaceutically acceptable carrier therefor. Also disclosed i...
12/12/2000
6147262Anti-neoplastic, anti-viral or anti-retroviral spermine derivatives
A compound having the formula: ##STR1## wherein: R1 -R6 may be the same or different and are H, alkyl or aralkyl having from 1 to 12 carbon atoms; m is an integer from 3 to 6, inclusive; n is an integer from 3 to 6, inclusive; exclud...
11/14/2000
6122956Method and apparatus for monitoring concentration of a slurry flowing in a pipeline
An on-line sensor for measuring volumetric concentration or percent solids of a slurry flowing in a pipeline includes a section of composite or dielectric pipe connected in the pipeline, with a plurality of sensing electrodes mounted around the periphery ...
09/26/2000
6121630Superconducting thin film and a method for preparing the same
A high-temperature superconducting thin film of compound oxide selected from the group consisting of: Y1 Ba2 Cu3 O7-x, Ho1 Ba2 Cu3 O7-x, Lu1 Ba2 Cu
09/19/2000
6121472Enhanced peanut products and plant lines
A peanut line and seed and oil products derived therefrom wherein the seed has an oleic acid content of from about 74% to about 84% and a linoleic acid content of from about 2% to about 8%, each based upon the total fatty acid content of the seed, and a r...
09/19/2000
6106068Automatic device for index guiding a movable part pivotably mounted about an axis on a part considered to be stationary relative to said axis
An automatic device (1) for index guiding a part (2) pivotably mounted about an axis (3) on a part (4) that is stationary relative to the axis (3). The device uses a mechanism (5) provided with a ratchet (6) that is pivotable between a number of positions...
08/22/2000
6099303Force recording orthodontic appliance
A removable orthodontic appliance includes a first force applicator spring and a data storage device that stores data corresponding to the force being applied by the spring. A potentiometer serves as a force measurer to indicate the magnitude of the extra...
08/08/2000
6092771Leg for a piece furniture with a telescopically movable portion
A furniture leg is disclosed with a telescopically movable portion for adjusting the height of the furniture wherein the leg includes an upper leg portion comprising a tube, a lower leg portion adapted to rest on the floor and the lower leg portion being ...
07/25/2000
6090997Method and composition for preventing surgical adhesions and tissue damage employing fluorinated polymers
An improved method for preventing adhesions during surgery. Tissue surfaces and surgical articles involved in the surgery are coated with a solution of a hydrophilic, polymeric material prior to manipulation of the tissue during surgery. The polymeric mat...
07/18/2000
6087430Thermoplastic polymers with dispersed fluorocarbon additives
A composition of matter formed by melt-blending certain thermoplastic polymers and from about 1.0 to about 7.5 wt. % of a fluorocarbon additive, the additive having a lower surface energy than that of the polymer; the blending resulting in a cooled admixt...
07/11/2000
6086283Universal joint for coordinate measuring device
A coordinate measuring machine (CMM), including three spherical base joints, a device for maintaining the base joints in a fixed spaced relation, and six actuator assemblies each having a variable length. Each of the base joints has a first end of two of ...
07/11/2000
6083991Anti-arrhythmic composition and methods of treatment
Pharmaceutical compositions for the treatment of cardiac arrhythmia comprising an effective anti-arrhythmic amount of at least one compound in association with a pharmaceutically acceptable, substantially non-toxic carrier or excipient, the compound havin...
07/04/2000
6083966Thiazoline acid derivatives
Phenyl- and pyridyl-substituted thiazoline acid derivatives useful in diagnosing and treating pathological conditions associated with an excess of trivalent metals in humans and animals....
07/04/2000
6063984Enhanced peanut products and plant lines
A peanut line and seed and oil products derived therefrom wherein the seed has an oleic acid content of from about 74% to about 84% and a linoleic acid content of from about 2% to about 8%, each based upon the total fatty acid content of the seed, and a r...
05/16/2000
6034139Anti-neoplastic, anti-viral or anti-retroviral spermine derivatives
A method of treatment for patients afflicted with malignant tumor cells in need of anti-neoplastic therapy, which cells are sensitive to a polyamine having one of the formulae: ##STR1## or (III) a salt thereof with a pharmaceutically acceptable acid ...
03/07/2000
 
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