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| Number | Title | Issue Date |
| 6527951 | Chromatographic column A chromatography column with filters having minimal volume. A stamped screen disk is coated with fluorocarbon polymer on both sides, leaving a center area open. The fluorocarbon polymer coating serves as a gasket, providing reliable sealing for pressure u... | 03/04/2003 |
| 6376044 | Enhanced resolution matrix-laser desorption and ionization TOF-MS sample surface A thin layer for sample analysis by matrix-assisted laser desorption mass spectrometry, comprising a matrix material in a supported dispersion wherein the support is a solid or is formed from a solid. The invention is also directed to a method of making a... | 04/23/2002 |
| 6299767 | High pressure capillary liquid chromatography solvent delivery system High pressure capillary liquid chromatography solvent delivery is effected at substantially low volume and atmospheric pressure. The low volume solvent composition is subsequently pressurized and expelled at high pressure into a receiving device such as a... | 10/09/2001 |
| 6188813 | Flow cell, analyte measurement apparatus and methods related thereto A modular flow cell having a high optical throughput, a long optical path length and a small cross-section. The modular flow cell configuration includes remote ports or connections for liquid and light input, and liquid and light output. The flow cell inc... | 02/13/2001 |
| 6158271 | Three capillary flow-through viscometer A method and apparatus for measuring the viscosity of a sample solution which comprises an input tube for transporting a sample solution flow towards a splitter for diverting input flow into two distinct flow streams where three capillary tubes are locate... | 12/12/2000 |
| 6140640 | Electrospray device A non-reactive electrospray needle structure that can be used with relatively low electrical potential introduced externally at a selectable location along the length of the needle structure. The electrospray device or apparatus includes a non-conductive ... | 10/31/2000 |
| 6137641 | Multi-channel plane grating monochromator Selective adjustment of astigmatism is provided by a spherical mirror bent to simultaneously increase radius of curvature in one plane and decrease radius of curvature in the plane at right angles thereto. In one implementation the mirror disposed in a mo... | 10/24/2000 |
| 6106238 | Bubble detection and recovery in a liquid pumping system A serial, dual piston high pressure fluid pumping system that overcomes the difficulties of gas in the fluid stream without the need for added mechanical valves or fluid paths. A bubble detection and recovery mechanism monitors compression and decompressi... | 08/22/2000 |
| 6099724 | Active pump phasing to enhance chromatographic reproducibility A fluid delivery method and apparatus implementing active phasing to actively restore the substantially exact mechanical positions of driven components in a delivery system in order to precisely reproduce the mechanical signature and hydraulic characteris... | 08/08/2000 |
| 6094262 | High temperature differential refractometry apparatus A differential refractometry apparatus that maintains optimal optical alignment of components while accurately providing differential refractometry measurements at elevated temperatures. The differential refractometry apparatus has a first thermal zone, a... | 07/25/2000 |
| 6071477 | Sample handling mechanism A sample handling mechanism including a direct drive carrier for positioning multiple trays or carousels of sample vials and a direct drive carousel handling mechanism that eliminates pulleys and belts and the problems associated therewith. The carousels ... | 06/06/2000 |
| 6064945 | System and method for determining molecular weight and intrinsic viscosity of a polymeric distribution using gel permeation chromatography A system and method for analyzing data from a gel permeation chromatography (GPC) or size exclusion chromatography (SEC) system for determining a polymeric sample's molecular weight distribution (MWD) and intrinsic viscosity law (IVL). Data from two or mo... | 05/16/2000 |
| 5900934 | Capillary chromatography detector apparatus An apparatus to effect multiple simultaneous separations to measure absorbance, comprising a photodetector array comprising a plurality of photosensitive elements connected to provide a serial output. The elements are typically pixels of a photodiode arra... | 05/04/1999 |
| 5897781 | Active pump phasing to enhance chromatographic reproducibility A fluid delivery method and apparatus implementing active phasing to actively restore the substantially exact mechanical positions of driven components in a delivery system in order to precisely reproduce the mechanical signature and hydraulic characteris... | 04/27/1999 |
| 5862832 | Gradient proportioning valve An improved gradient proportioning valve compensates for hydraulic inertia in a compact, reliably sealed valve assembly that is less susceptible to unswept volumes and gas permeation. A flat diaphragm is located within an accumulator volume integral to a ... | 01/26/1999 |