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Attorney: Meigs; J. Timothy


Number of patents: 60
Last date: November 18, 2003

1    
NumberTitleIssue Date
6649375Adenoviral vectors for enhanced gene expression
An adenoviral vector including at least one DNA sequence encoding a clotting factor, such as, for example, Factor VIII, or Factor IX. Such vectors may be administered to a host in an amount effective to treat hemophilia in the host. The vectors infect hep...
11/18/2003
6319673PCR-based detection and quantification of Tapesia yallundae and Tapesia acuformis
The present invention provides primers and probes for use in TaqMan™ quantitative PCR assays for the detection of Tapesia yallundae (syn. Pseudocercosporella herpotrichoides W-type) and Tapesia acuformis (syn. Pseudocercosporella herpotrichoides R-type)...
11/20/2001
6300544Cytochrome P450 monooxygenases
Cytochrome P450II dependent monooxygenases and DNA molecules encoding these monooxygenases are provided, which are able to catalyze the biosynthetic conversion of aldoximes to nitrils and the conversion of said nitrils to the corresponding cyan...
10/09/2001
6300103Anti-microbial proteins
An anti-microbial protein comprising a peptide having the amino acid sequence: AA1 -AA2 -AA3 -Cys-AA5 -AA6 -AA7 -AA8 -AA9 -Cys-AA11 -AA12 -AA13
10/09/2001
6278041Peroxidase gene sequences
A anionic peroxidase gene sequence is isolated from Nicotiana tomentisiformis. In addition, synthetic Nicotiana tomentisiformis and Nicotiana sylvestris peroxidase gene sequences are optimized for expression in plants. The peroxidase gene sequences may be...
08/21/2001
6262342DNA sequences encoding polypeptides having ଲ-1,3-glucanase activity
The present invention provides chemically regulatable DNA sequences capable of regulating transcription of an associated DNA sequence in plants or plant tissues, chimeric constructions containing such sequences, vectors containing such sequences and chime...
07/17/2001
6251862Insecticidal toxins from the parasitic wasp bracon hebeter
Novel polypeptides are isolated from the venom of the parasitic wasp, Bracon hebetor, and are designated Brh-I to Brh-V. These polypeptides are paralytic and/or toxic to insects. The entire amino acid sequence of Brh-I and the DNA encoding it is also dete...
06/26/2001
6242574Antimicrobial proteins
Isolated proteins having anti-fungal activity against at least Cercospora spp. The proteins contain an amino acid sequence which has at least 95% sequence identity to any of the following sequences: SEQ ID NO:3 wherein the amino acid in position 80 is ala...
06/05/2001
6239264Genomic DNA sequences of ashbya gossypii and uses thereof
The present invention relates to the terminal sequencing of random genomic fragments performed with the filamentous fungus A.gossypii, to the sequences obtained therewith and the use of the sequences for forensic identification, to characterize genes and ...
05/29/2001
6232525Mutant plants and uses therefor
Methods are provided for selecting parental plants exhibiting disease resistance and for using these plants in breeding programs. In one method of the invention, constitutive immunity (cim) mutants are screened for either resistance to a pathogen of inter...
05/15/2001
6221595Detection of Monilinia spp. using the polymerase chain reaction
The present invention relates to the use of primers in polymerase chain reaction assays for the detection of fungal pathogens, particularly Monilinia laxa and Monilinia fructicola. Specific primers are identified as being useful for the indentification of...
04/24/2001
6204246Hybrid toxin
The present invention provides, inter alia, a B.t. hybrid toxin fragment comprising at its C-terminus domain III of a first Cry protein, or a part of said domain or a protein substantially similar to said domain; and comprising at its N-terminus the N-ter...
03/20/2001
6204057Polynucleotides and the proteins encoded thereby, suitable for controlling lamellicorn beetles
The invention relates to isolated polynucleotides and the proteins encoded thereby, and to their use in controlling lamellicorn beetles (Scarabaeidae). In addition, the invention relates to a method of producing those proteins. The polynucleotides of the ...
03/20/2001
6133417Cytochrome P-450 monooxygenases
New cytochrome P-450 dependent monooxygenases and DNA molecules encoding these monooxygenases are provided, which are able to catalyze the biosynthetic pathway from amino acids to their corresponding cyanohydrins, the presursors of the cyanogenic glycosid...
10/17/2000
6121029Genes for the biosynthesis of epothilones
Nucleic acid molecules are isolated from Sorangium cellulosum that encode polypeptides necessary for the biosynthesis of epothilone. Disclosed are methods for the production of epothilone in recombinant hosts transformed with the genes of the invention. I...
09/19/2000
6117670Pyrrolnitrin biosynthesis genes and uses thereof
The present invention is directed to the production of pyrrolnitrin in a host via recombinant expression of the polypeptides needed to biologically synthesize pyrrolnitrin. Genes isolated from P. fluorescens, P. pyrrocinia, B. cepacia, and M. fulvus that ...
09/12/2000
6107544Method for breeding disease resistance into plants
Methods are provided for selecting parental plants exhibiting disease resistance and for using these plants in breeding programs. In one method of the invention, constitutive immunity (cim) mutants are screened for either resistance to a pathogen of inter...
08/22/2000
6091004Gene encoding a protein involved in the signal transduction cascade leading to systemic acquired resistance in plants
The invention concerns the location and characterization of a gene (designated NIM1) that is a key component of the SAR pathway and that in connection with chemical and biological inducers enables induction of SAR gene expression and broad spectrum diseas...
07/18/2000
6071698DNA extraction buffer and method of use thereof
Internal Transcribed Spacer (ITS) DNA sequences from the ribosomal RNA gene region are described for different species and strains of Helminthosporium carbonum, Helminthosporium turcicum, Helminthosporium maydis, Cercospora zeae-maydis, Kabatiella zeae an...
06/06/2000
6057490Method for selecting disease resistant mutant plants
Methods are provided for selecting parental plants exhibiting disease resistance and for using these plants in breeding programs. In one method of the invention, constitutive immunity (cim) mutants are screened for either resistance to a pathogen of inter...
05/02/2000
6031153Method for protecting plants
The present invention concerns a method of protecting plants from pathogen attack through synergistic disease resistance attained by applying a conventional microbicide to immunomodulated plants. Immunomodulated plants are those in which SAR is activated ...
02/29/2000
5986082Altered forms of the NIM1 gene conferring disease resistance in plants
The NIM1 gene product is a structural homologue of the mammalian signal transduction factor I.kappa.B subclass ଱. The present invention exploits this discovery to provide altered forms of NIM1 that act as dominant-negative regulators of the systemic...
11/16/1999
5955348Genetically modified pseudomonas strains with enhanced biocontrol activity
Strains of Pseudomonas have been genetically engineered to have enhanced biocontrol properties. The strains of the invention are particularly effective against plant pathogenic fungi such as species of Rhizoctonia and Pythium, because the strains produce ...
09/21/1999
5955274Detection of fungal pathogens using the polymerase chain reaction
DNA sequences from the Internal Transcribed Spacers of the ribosomal RNA gene region are described for different species and strains of Septoria, Pseudocercosporella, Fusarium and Mycosphaerella. Specific primers from within these sequences are identified...
09/21/1999
5939602DNA molecules encoding plant protoporphyrinogen oxidase and inhibitor-resistant mutants thereof
The present invention provides novel DNA sequences coding for plant protoporphyrinogen oxidase (protox) enzymes from soybean, wheat, cotton, sugar beet, rape, rice and sorghum. In addition, the present invention teaches modified forms of protox enzymes th...
08/17/1999
5891688DNA encoding lemA-independent GacA and its use in activating gene expression
The present invention exploits the discovery that certain single base changes in the gacA gene coding sequence, which result in certain single amino acid changes in the encoded GacA protein, render it LemA-independent. The present invention therefore prov...
04/06/1999
5880328DNA encoding plant chitinases
The present invention provides chemically regulatable DNA sequences capable of regulating transcription of an associated DNA sequence in plants or plant tissues, chimeric constructions containing such sequences, vectors containing such sequences and chime...
03/09/1999
5869719Transgenic plants having increased biotin content
The present invention reveals that biotin biosynthesis in a plant is enhanced when the level of one or more of the enzymes in the plant biotin biosynthetic pathway is increased. Based upon this revelation, methods that increase the level of one or more bi...
02/09/1999
5859335Enhanced biotin biosynthesis in plant tissue
The present invention reveals that biotin biosynthesis in a plant is enhanced when the level of one or more of the enzymes in the plant biotin biosynthetic pathway is increased. Based upon this revelation methods which increase the level of one or more bi...
01/12/1999
5856154Method of protecting plants from oomycete pathogens
The present invention provides chemically regulatable DNA sequences capable of regulating transcription of an associated DNA sequence in plants or plant tissues, chimeric constructions containing such sequences, vectors containing such sequences and chime...
01/05/1999
5851766Process for isolating chemically regulatable DNA sequences
The present invention provides chemically regulatable DNA sequences capable of regulating transcription of an associated DNA sequence in plants or plant tissues, chimeric constructions containing such sequences, vectors containing such sequences and chime...
12/22/1998
5847258DNA encoding ଲ-1,3-glucanases
The present invention provides chemically regulatable DNA sequences capable of regulating transcription of an associated DNA sequence in plants or plant tissues, chimeric constructions containing such sequences, vectors containing such sequences and chime...
12/08/1998
5827695Detection of wheat fungal pathogens using the polymerase chain reaction
Internal Transcribed Spacer (ITS) DNA sequences from the ribosomal RNA gene region are described for different species and strains of wheat fungal pathogens, including Fusarium spp. and Microdochium nivale. Specific primers from within these sequences are...
10/27/1998
5817502Genes for the synthesis of pyrrolnitrin
The present invention is directed to the production of an antipathogenic substance (APS) in a host via recombinant expression of the polypeptides needed to biologically synthesize the APS. Genes encoding polypeptides necessary to produce particular antipa...
10/06/1998
5814453Detection of fungal pathogens using the polymerase chain reaction
Internal Transcribed Spacer (ITS) DNA sequences from the ribosomal RNA gene region are described for different species and strains of cereal fungal pathogens, including Septoria, Pseudocercosporella, Fusarium, Microdochium, and Mycosphaerella. Specific pr...
09/29/1998
5804693Chemically regulatable and anti-pathogenic DNA sequences and uses thereof
The present invention provides chemically regulatable DNA sequences capable of regulating transcription of an associated DNA sequence in plants or plant tissues, chimeric constructions containing such sequences, vectors containing such sequences and chime...
09/08/1998
5800997Detection of maize fungal pathogens using the polymerase chain reaction
Internal Transcribed Spacer (ITS) DNA sequences from the ribosomal RNA gene region are described for different species and strains of Helminthosporium carbonum, Helminthosporium turcicum, Helminthosporium maydis, Cercospora zeae-maydis, Kabatiella zeae an...
09/01/1998
5792904Method for breeding disease resisteance into plants
Methods are provided for selecting parental plants having disease resistance and for using these plants in breeding programs. In one method of the invention, lesion mimic mutants are screened for either resistance to a pathogen of interest or for the expr...
08/11/1998
5789214Method of inducing gene transcription in a plant
The present invention provides chemically regulatable DNA sequences capable of regulating transcription of an associated DNA sequence in plants or plant tissues, chimeric constructions containing such sequences, vectors containing such sequences and chime...
08/04/1998
5777200Chemically regulatable and anti-pathogenic DNA sequences and uses thereof
The present invention provides chemically regulatable DNA sequences capable of regulating transcription of an associated DNA sequence in plants or plant tissues, chimeric constructions containing such sequences, vectors containing such sequences and chime...
07/07/1998
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