Quotables
"The abolishment of pain in surgery is a chimera. It is absurd to go on seeking it...knife and pain are two words in surgery that must forever be associated in the consciousness of the patient."
Dr. Alfred Velpeau, French surgeon ; 1839
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| Number | Title | Issue Date |
| 8163524 | Comparative analysis of extracellular RNA species The invention provides methods for detecting tumor-associated RNA in plasma, serum, and other bodily fluids. In particular, the invention provides methods for detecting translocated gene RNA, including fusion gene RNA, in plasma or serum or other bodily fluids. ... | 04/24/2012 |
| 8158394 | Genetically stable plasmid expressing PDH and FDH enzymes Bi-cistronic plasmids used for the expression of formate dehydrogenase (FDH) and modified phenylalanine dehydrogenase (PDHmod) are provided. ... | 04/17/2012 |
| D657842 | Fish hook | 04/17/2012 |
| 8152195 | Modular suspension system and components thereof An elastomeric spring suspension is described for supporting a longitudinally extending vehicle frame rail above first and second axles forming a tandem axle configuration. The suspension includes a frame hanger assembly mounted to the vehicle frame rail. The frame ... | 04/10/2012 |
| D655212 | Electrical tester | 03/06/2012 |
| 8106167 | Human anti-NGF neutralizing antibodies as selective NGF pathway inhibitors This invention provides antibodies that interact with or bind to human nerve growth factor (NGF) and neutralize the function of NGF thereby. The invention also provides pharmaceutical compositions of these antibodies and methods for neutralizing NGF function, and pa... | 01/31/2012 |
| D653294 | Foot propelled vehicle | 01/31/2012 |
| 8101627 | Stereoisomerically enriched 3-aminocarbonyl bicycloheptene pyrimidinediamine compounds and their uses The present invention provides stereoisomers and stereoisomeric mixtures of 3-aminocarbonyl-bicycloheptene-2,4-pyrimidinediamine compounds having antiproliferative activity, compositions comprising the compounds and methods of using the compounds to inhibit cellular... | 01/24/2012 |
| 8059060 | Unitary solderless monopole antenna for in-duct use An improved monopole antenna for in-duct use is disclosed. The antenna comprises a center pin rod disposed coupled to a connector housing by a molded dielectric. The center pin rod includes a pin portion which is disposed through a portion of a connector portion of ... | 11/15/2011 |
| 8053408 | Methods for treating obesity using fibroblast growth factor-like polypeptides The present invention provides methods for reducing body weight in a mammal using Fibroblast Growth Factor-like (FGF-like) polypeptides and nucleic acid molecules encoding the same. ... | 11/08/2011 |
| 8052166 | Tie-plate and frame hanger of a suspension assembly An elastomeric spring suspension is described for supporting a longitudinally extending vehicle frame rail above first and second axles forming a tandem axle configuration. The suspension includes a frame hanger assembly mounted to the vehicle frame rail. The frame ... | 11/08/2011 |
| 8044024 | Identifying modulators of fibroblast growth factor-like polypeptides The present invention provides novel Fibroblast Growth Factor-like (FGF-like) polypeptides and nucleic acid molecules encoding the same. The invention also provides vectors, host cells, antibodies and methods for producing FGF-like polypeptides. Also provided for ar... | 10/25/2011 |
| 8043835 | Methods for detecting and monitoring cancer using extracellular RNA The invention provides methods, reagents and kits for using extracellular RNA in bodily fluids including plasma and serum to detect, infer, or monitor diseases such as cancer and other neoplasia. ... | 10/25/2011 |
| 8041522 | System and method for recursively estimating battery cell total capacity A system and method for determining an estimated battery cell total capacity indicative of a total capacity of a battery cell is provided. The method includes receiving a first battery cell state-of-charge estimate at a first time and receiving a second battery cell... | 10/18/2011 |
| 8030275 | Methods for treating obesity using fibroblast growth factor-like polypeptides The present invention provides methods for reducing body weight in a mammal using Fibroblast Growth Factor-like (FGF-like) polypeptides and nucleic acid molecules encoding the same. ... | 10/04/2011 |
| 8030031 | Method enabling use of extracellular RNA extracted from plasma or serum to detect, monitor or evaluate cancer This invention relates to the use of tumor-derived or associated extracellular ribonucleic acid (RNA) found circulating in the plasma or serum fraction of blood for the detection, monitoring, or evaluation of cancer or premalignant conditions. Specifically, this inv... | 10/04/2011 |
| 8007787 | Human cystathionine β-synthase variants and methods of production thereof Human cystathionine β-synthase variants are disclosed, as well as a method to produce recombinant human cystathionine β-synthase and variants thereof. More particularly, the role of both the N-terminal and C-terminal regions of human CBS has been studied, and a va... | 08/30/2011 |
| 7980852 | Method and impression tray for producing a dental mold The invention relates to a method for producing a dental mold on the basis of a thermoplastic film (4), and to an impression tray (1) for producing such a dental mold (2). The impression tray (1) is charged with a kneadable, malleable mat... | 07/19/2011 |
| 7977672 | Organic light-emitting device with field-effect enhanced mobility A two-terminal organic light-emitting device structure is presented with low absorption losses and high current densities. Light generation and emission occur at a predetermined distance from any metallic contact, thereby reducing optical absorption losses. High cur... | 07/12/2011 |
| 7972817 | Method enabling use of extracellular RNA extracted from plasma or serum to detect, monitor or evaluate cancer This invention relates to the use of extracellular ribonucleic acid (RNA) found circulating in the plasma or serum fraction of blood. Specifically, this invention enables the extraction of circulating RNA from plasma or serum and utilizes nucleic acid amplification ... | 07/05/2011 |
| 7968317 | Detection of 5T4 RNA in plasma and serum This invention provides methods for detecting the presence of malignant or premalignant cells, or trophoblastic cells in a human wherein the malignant, premalignant or trophoblastic cells express 5T4. The methods of the invention detect 5T4 RNA in blood, blood plasm... | 06/28/2011 |
| 7487304 | Packet processor memory interface with active packet list A mechanism receives start and done commands containing packet identifiers or sequence numbers from a packet processing engine for packets for which processing is being started and for which processing has completed respectively. Upon receiving a packet start comman... | 02/03/2009 |
| 7463906 | Method and apparatus for collecting information for use in a smart antenna system A method of obtaining information for use in a smart antenna system is provided. The method includes monitoring an interface between a base station controller and a base station transceiver to receive signaling information being communicated via the interface. The m... | 12/09/2008 |
| 7453752 | Method for hiding a refresh in a pseudo-static memory with plural DRAM sub-arrays and an on-board address decoder A method and device for hiding refresh operations during accesses to sub-arrays of a pseudo-static memory device. By refreshing sub-arrayj while filling the row Ri (where i≠j) corresponding to sub-arrayi, refresh operations can be ... | 11/18/2008 |
| 7425631 | Compounds and methods of use Selected compounds are effective for treatment of pain and diseases, such as inflammation mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions and methods for... | 09/16/2008 |
| 7420079 | Methods and compounds for producing dipeptidyl peptidase IV inhibitors and intermediates thereof Methods and compounds for production of cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV are provided. ... | 09/02/2008 |
| 7420063 | Process for preparing a dipeptidyl peptidase IV inhibitor and intermediates employed therein A process is provided for preparing a dipeptidyl peptidase IV inhibitor of the structure is treated with TFAA in isopropyl acetate to protect the tertiary hydroxyl group as a trifluoroacetate group to form 4 | 09/02/2008 |
| 7417072 | Blockade of Pin1 prevents cytokine production by activated immune cells The invention provides pharmaceutical compositions and methods of treating immunological disorders. The invention also provides pharmaceutical compositions and methods of inducing eosinophil apoptosis, and methods for treating eosinophil-associated disorders compris... | 08/26/2008 |
| 7410764 | Detection of extracellular tumor-associated nucleic acid in blood plasma or serum using nucleic acid amplification assays This invention relates to detection of specific extracellular nucleic acid in plasma or serum fractions of human or animal blood associated with neoplastic or proliferative disease. Specifically, the invention relates to detection of nucleic acid derived from mutant... | 08/12/2008 |
| 7406117 | XDSL multi-hybrid modem with power spectral density shaping Power spectral density shaping can be used in an XDSL system in order to adjust power spectral density properties of signals transmitted by an XDSL modem. The XDSL modem may include a power spectral density shaping filter, which can be adjusted to change the power s... | 07/29/2008 |
| 7399782 | Polyether brevetoxin derivatives as a treatment for cystic fibrosis, mucociliary dysfunction, and pulmonary diseases Disclosed are compounds that are derivatives of brevetoxin, or PbTx, pharmaceutical formulations comprising the compounds, and methods of regulating mucus transport in a cell, treating mucociliary dysfunction and diseases related to decreased mucus transport, wherei... | 07/15/2008 |
| 7391784 | Method and system for communicating state information between devices of a communications network A method and system of communicating state information between devices of a communications network is provided. A gateway of a packet network may change operating states during transmission of packets to another gateway. The gateway may indicate the state change to ... | 06/24/2008 |
| 7385939 | Network management apparatus and method for determining the topology of a network A network management apparatus and method for determining the topology of a network in which a Spanning-Tree protocol is implemented, is disclosed in which address table data is obtained from the ports of the core network devices on the network, and the identity of ... | 06/10/2008 |
| 7348136 | Method and device for detecting feline immunodeficiency virus A method and device for determining a feline immunodeficiency virus infection or vaccination in an animal. The method includes contacting a biological sample from a felid with various FIV polypeptides and determining the binding of antibodies in the sample to the po... | 03/25/2008 |
| 7326184 | Connector device An adapter for use in connecting a vacuum source with a breast shield is disclosed including a housing with at least one female coupling component formed therein, at least one male coupling component that is adapted to attach to a tube at one end for conveying press... | 02/05/2008 |
| 7316818 | Liposome drug delivery of polycyclic, aromatic, antioxidant or anti-inflammatory compounds This invention comprises pharmaceutical compositions for administering a polycyclic, aromatic, antioxidant or anti-inflammatory compound to an animal. Particularly provided are proliposomal compositions that are advantageously used to deliver polycyclic, aromatic, a... | 01/08/2008 |
| 7309584 | Mutations of the MDR1 P-glycoprotein that improves its ability to confer resistance to chemotherapeutic drugs The present invention provides mutant P-glycoprotein polypeptides that confer increased resistance to certain chemotherapeutic drugs relative to wild-type P-glycoprotein or P-glycoprotein having a glycine to valine substitution at position 185, and nucleic acid mole... | 12/18/2007 |
| 7305694 | Method and apparatus for remotely controlling a receiver according to content and user selection System and method for automatically controlling a media receiver by instructing the media receiver to use a particular receiver connection and to play a selected media unit using one of a plurality of play modes according to characteristics of the media unit. Media ... | 12/04/2007 |
| 7300210 | Bearing locking collar with laminated plates A locking collar comprising an annular collar having an outer surface, an inner surface, and a first end positioned opposite a second end defining a gap therebetween, and a locking component extending from the first end of the annular collar and into engagement with... | 11/27/2007 |
| 7291592 | Method for treating patients with massive blood loss Methods for treating a mammal suffering from massive blood loss comprising administering to the mammal a polymerized hemoglobin solution. ... | 11/06/2007 |
