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Patent No. 5421089

Fork With Timer

A fork with timer for providing a cue to a user after an elapsed period of time for indicating that another bite of food using the fork may be taken.

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Attorney: McConathy; Evelyn H.


Number of patents: 62
Last date: March 13, 2012

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NumberTitleIssue Date
8135449Imaging of oxygen by phosphorescence quenching
A method of real-time imaging of dissolved oxygen concentration, comprising adding an oxygen-quenched phosphorescent composition to a sample, exciting phosphorescence in the composition by illuminating the sample with pulses of light, detecting phosphorescence inten...
03/13/2012
8124056High throughput genetic screening of lipid and cholesterol processing using fluorescent compounds
The present invention utilizes fluorescent lipids, particularly quenched phospholipid or cholesterol analogues, to facilitate screening for phenotypes representing perturbations of lipid and/or cholesterol processing in a vertebrate; screening for genetic mutations ...
02/28/2012
8114442Transdermal pharmaceutical delivery compositions
A pharmaceutically delivery system and method of use therefor are described comprising a pharmaceutically active agent and acidified nitrite as an agent to produce local production of nitric oxide at the skin surface. The dosage form may be in any pharmaceutically a...
02/14/2012
8101564Methods for regulating osteoclast differentiation and bone resorption using LRRc17
Provided is a purified, negative regulator of osteoclast differentiation and bone resorption, specifically LRRc17. Further provided are methods and compositions for treating degenerative bone disorders, and treatments and prophylactic approaches for regulating bone ...
01/24/2012
8076936Reducing imaging-scan times for MRI systems
Provided are methods and systems for rapid MRI imaging-scanning that provides 2D or 3D coverage, high precision, and high-temporal efficiency, without exceeding SAR limits. In one embodiment, a pulse sequence process is performed that includes a T1ρ prep...
12/13/2011
8029989Method using snail transcriptional repressor
Provided is a prognostic molecular marker for breast cancer recurrence. Expression of Snail, a zinc finger transcriptional repressor gene, is correlated to the risk of breast cancer recurrence, and to the likelihood of recurrence-free survival in subjects diagnosed ...
10/04/2011
7917519Categorized document bases
A method of managing information comprises generating a categorized document base. Generating the document base comprises providing a pre-existing classification of things other than documents, providing a source collection of documents, and automatically assessing ...
03/29/2011
7856911Automated scrap wire removal method and apparatus
A module for automatic scrap wire isolating and removal is used in systems such as wire insulation lines for extricating scrap wires while minimally interfering with the mechanized wire insulation process. One such module includes a knife assembly with a knife, a sc...
12/28/2010
7769214Method for measuring structural thickness from low-resolution digital images
Provided are fuzzy distance transform-based methods, and an algorithm therefor, for analyzing digital images defining a volumetric region of an object from a digital image comprising finding a set of points in the image to generate a fuzzy subset, and calculating th...
08/03/2010
7756891Process and system for matching products and markets
The present invention provides a search method and system for matching a commodity to one or more applications for using the commodity. A plurality of properties associated with the commodity are identified. A collection of documents for searching for a plurality of...
07/13/2010
7741111Pregnancy, up-regulated non-ubiquitous CaM kinase
This invention relates generally to a novel CaM multi-functional protein kinase, which has been named Pregnancy Up-Regulated, Nonubiquitous CaM Kinase (PNCK), and to the nucleotide sequence encoding it. The kinase is temporally expressed during postnatal mammary dev...
06/22/2010
7728159Organopolysiloxanes containing phosphonic groups, method for the production and use thereof
The invention relates to new compounds of the formula, wherein R and R1 are each independently hydrogen, a linear or branched C1-40 alkyl, C2-40 alkenyl or C2-40 alkynyl group, an aryl or C1-40 alkylaryl group o...
06/01/2010
7727219Sterile system and methods for collecting, transporting, storing and cyropreserving body fluids
The present invention provides a method for expanding a pre-assembled closed, sterile container system used for the collection, transportation, storage and cryopreservation of biological fluids, such as, blood, bone marrow or umbilical cord blood. The closed sterile...
06/01/2010
7705596System and method for minimizing MRI-imaging artifacts
Methods of, and systems for, simultaneously compensating for external-magnetic-field inhomogeneity as well as radiofrequency magnetic-field inhomogeneity in an MRI system. In one method embodiment, a pulse sequence is applied when the transmitter-reference frequency...
04/27/2010
7653639Computer algorithms and methods for product safety
The invention comprises systems, methods and a computerized data management device for creating and using data relating to a medical or non-medical product or device to enhance the safety of the product or device. A vast amount of data regarding adverse events assoc...
01/26/2010
7643664Virtual bone biopsy (VBB) system
The present invention comprises a system and method for analyzing trabecular bone structure. A means for scanning the trabecular bone using a magnetic resonance image (MRI) scanner generates bone image data, which is then processed including correcting, deshading an...
01/05/2010
7618584Bag system for the cryopreservation of body fluids
The invention relates to a bag system for the cryopreservation of body fluids, that is blood, bone marrow or umbilical cord blood, the parts of the bag system being sterilized, and separable from one another, wherein liquids which permit and/or assist cryopreservati...
11/17/2009
7575890Method for rapid detection and evaluation of cultured cell growth
Provided is a method and system for the rapid and accurate detection of growth and metabolism of a cellular microorganism in a population of microorganisms in a non-liquid, culture medium. Further provided is a gelled culture medium containing a non-toxic, water-sol...
08/18/2009
7488467High throughput genetic screening of lipid and cholesterol processing using fluorescent compounds
The present invention utilizes fluorescent lipids, particularly quenched phospholipid or cholesterol analogues, to facilitate screening for phenotypes representing perturbations of lipid processing; screening for genetic mutations that lead to disorders of phospholi...
02/10/2009
7477770Virtual bone biopsy
The present indention comprises a system and method for analyzing trabecular bone structure. A means for scanning the trabecular bone using a magnetic resonance image (MRI) scanner generates bone image data, which is then processed including correcting, deshadi4 and...
01/13/2009
7447595Heterologous protein production using the twin arginine translocation pathway
Provided are means for evaluating and identifying putative substrates of the twin arginine translocation (Tat) secretory pathway in Streptomyces and other bacterial species. Also provided, therefore, are simple ways to express, secrete and purify correctly fo...
11/04/2008
7423141Inhibitors of endothelin-1 synthesis
Sequences in human preproendothelin-1 mRNA are described against which antisense oligonucleotides can be used to inhibit the synthesis of endothelin-1. This inhibition of endothelin-1 synthesis may be used to treat diseases where excess production of endothelin-1 is...
09/09/2008
7378111Regulation of GSK-3α activity for the treatment or prevention of Alzheimer's disease
Provided is a novel use of therapeutic concentrations of an inhibitor of glycogen synthase kinase-3 (GSK-3), including lithium or any other GSK-3 inhibitor, to block, reduce or inhibit processing of amyloid precursor proteins to beta-amyloid (Aβ) peptides, which ar...
05/27/2008
7368113Hormonally up-regulated, neu-tumor-associated kinase
This invention relates generally to a novel serine/threonine protein kinase, specifically to hormonally up-regulated, neu-tumor-associated kinase (HUNK); and to the nucleotide sequence encoding it. The kinase is temporally expressed during postnatal mammary developm...
05/06/2008
7273050Jet endotracheal device and its use in intubation
An endotracheal device includes a unit with a pair of tubes and a beveled distal end. One tube is used for jet ventilation, while a monitoring catheter is provided inside the second, larger tube. The device is useful for otherwise difficult intubations. ...
09/25/2007
7255887Use of Bowman Birk inhibitor for the treatment of multiple sclerosis and other autoimmune diseases
Provided is a use for Bowman Birk Inhibitor (BBI), as administered in Bowman Birk Inhibitor Concentrate (BBIC), for the treatment of autoimmune diseases in a patient, wherein the disease is characterized by chronic inflammation, such as rheumatoid arthritis; and mor...
08/14/2007
7257568Process and system for matching products and markets
The present invention provides a search method and system for matching a commodity to one or more applications for using the commodity. A plurality of properties associated with the commodity are identified. A collection of documents for searching for a plurality of...
08/14/2007
7155416Biometric based authentication system with random generated PIN
Provided are apparatus, system and methods for accessing information utilizing an authentication system for verifying that a user is an authorized user of the information access device, and that activation of the device is valid to access the information. The authen...
12/26/2006
7101701Method to reduce contamination when culturing mycobacteria
Provided is a method for culturing Mycobacteria in the presence of a class A lantibiotic, thereby inhibiting or reducing bacterial contamination in the culture, without significantly disadvantageously affecting or retarding mycobacterial growth. Further provi...
09/05/2006
7072706Equilibration method for high resolution imaging of lung compliance and distribution of functional residual capacity
The present invention offers novel equilibration methods for very high resolution, three-dimensional imaging of imaging of lung compliance and distribution of functional residual capacity (FRC) in the lung using hyperpolarized helium-3 (3He) gas (H3
07/04/2006
7064226Organopolysiloxanes containing phosphonic groups, method for the production and use thereof
The invention relates to new compounds of the formula, wherein R and R1 are each independently hydrogen, a linear or branched C1-40 alkyl, C2-40 alkenyl or C2-40 alkynyl group, an aryl or C1-40 alkylaryl group o...
06/20/2006
7011623Ex vivo remodeling of excised blood vessels for vascular grafts
The present invention provides an ex vivo vascular remodeling methods and system by which an excised, small diameter blood vessel can be harvested and expanded to provide viable vascular grafts, as demonstrated at the physical and molecular levels, and as optimized ...
03/14/2006
6982743Multispectral omnidirectional optical sensor and methods therefor
Provided is a multispectral and omnidirectional imaging sensor and system that produces improved surround awareness, as well as methods of use therefor. The multispectral omnidirectional optical sensor device comprises a series of view and reflecting mirrors for spl...
01/03/2006
6885762Scale-based image filtering of magnetic resonance data
The invention provides novel scale-based filtering methods that use local structure size or “object scale” information to arrest smoothing around fine structures and across even low-gradient boundaries. One method teaches a weighted average over a scale-dependen...
04/26/2005
6858011Method and apparatus to control microbubble destruction during contrast-enhanced ultrasound imaging, and uses therefor
Methods and apparatus are provided for controlling fluid flow or perfusion, wherein gas-filled microbubbles are used as ultrasound contrast-enhancing agents, and wherein the method comprises separating the removal of the contrast agent due to flow from the removal o...
02/22/2005
6836114Pulse imaging sequences and methods for T1p-weighted MRI
Provided are pulse imaging sequences and methods for 2D multi-slice T1ρ-weighted and 3D T1ρ-weighted magnetic resonance imaging (MRI). Further provided is a self-compensating spin-locking sequence for correcting and reducing artifacts in T
12/28/2004
6835394Polymersomes and related encapsulating membranes
The present invention provides biocompatible vesicles comprising semi-permeable, thin-walled encapsulating membranes which are formed in an aqueous solution, and which comprise one or more synthetic super-amphiphilic molecules. When at least one super-amphiphile mol...
12/28/2004
6775401Subvoxel processing: a method for reducing partial volume blurring
The present invention comprises a novel method, system and device for post-processing images, such as trabecular bone images, obtained by MRI, CT, or other image technologies, to provide increasing apparent image resolution and to alleviate the effects of partial vo...
08/10/2004
6767564Use of bowman birk inhibitor for the treatment of multiple sclerosis and other autoimmune diseases
The present invention provides a non-toxic therapy and a novel use for Bowman Birk Inhibitor (BBI), as administered in Bowman Birk Inhibitor Concentrate (BBIC), for the treatment of autoimmune diseases in a patient, wherein the disease is characterized by chronic in...
07/27/2004
6757898Electronic provider—patient interface system
The present invention provides a communication system for providing automated, electronic communications between at least one health-care provider and a plurality of users of the health-care provider, wherein the communications occur over a communications network th...
06/29/2004
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