3M employee and church chorister Art Fry needed something to temporarily mark pages in his hymnal. He was in luck because his colleague, Spencer Silver, accidentally developed a glue that was too weak for other purposes. After initially discouraging consumer response, Post-it Notes became a hit in 1979.
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| Number | Title | Issue Date |
| 8182783 | Rapid microwave process for purification of nanocarbon preparations A novel microwave-assisted process is described for the rapid removal of catalytic metal and non-desirable carbon impurities in fullerene, single wall, and multiple wall carbon nanotube preparations. The purification process is carried out at various programmed pres... | 05/22/2012 |
| 8182294 | Connector assembly and related methods of use Connector assemblies for use in wiring/cabling applications are disclosed. The connector assemblies include first and second jack openings that facilitate interaction between plugs that feature contact layouts according to the IEC 60603-7-7 standard. Cable/plug comb... | 05/22/2012 |
| 8182212 | Pump housing coupling An assembly is disclosed for forming a fluid-tight seal between a pump housing and a seal plate. The housing includes a first flange with a first plurality of apertures formed therein, and the seal plate includes a second flange with a second plurality of apertures ... | 05/22/2012 |
| 8182040 | Forward tiltable motor vehicle seat with hinge mountings A forward tiltable motor vehicle seat having a seat carrier, a seat back and a hinge mounting arranged therebetween. The hinge mounting has an upper hinge arm connected to the seat back and a lower hinge arm hinged to the seat carrier about a forward tilt axis. The ... | 05/22/2012 |
| 8181431 | Sterile de-molding apparatus and method Apparatus for molding and filling a device having a body defining an opening in communication with an interior chamber for receiving a substance therein, and a closure including a penetrable and resealable portion for sealing the opening and substance received in th... | 05/22/2012 |
| D660199 | Stud with circular channels for a fashion article | 05/22/2012 |
| D660107 | Utility knife blade | 05/22/2012 |
| 8178347 | Gene regulatory networks and methods of interdiction for controlling the differentiation state of a cell The invention provides a method of modulating a regulatory state of a cell. The method consists of: (a) identifying a point of interdiction within a cis regulatory network specifying a genetic regulatory architecture of a cell, and (b) introducing into a progenitor ... | 05/15/2012 |
| 8178092 | Methods of treating psoriasis by administration of antibodies to the p40 subunit of IL-12 and/or IL-23 The invention provides a method of treating psoriasis in a subject by administering to a subject an antibody capable of binding to the p40 subunit of IL-12 and/or IL-23. ... | 05/15/2012 |
| 8178049 | Carbon nanotube or carbon nanofiber production apparatus and recovery apparatus A discharge gas containing carbon nanotubes and discharged from a reactor unit (12) is led to a filter (26) through a discharge pipe (24). A blower (28) is disposed downstream from the filter (26). The blower (28) is used to... | 05/15/2012 |
| D659592 | Stud with circular channels for a fashion article | 05/15/2012 |
| D659554 | Wristwatch | 05/15/2012 |
| 8173785 | Peptide nucleic acid probes for analysis of certain species The present invention relates to peptide nucleic acid (PNA) probes, PNA probe sets and methods for the analysis of certain Staphylococcus species optionally present in a sample. The invention further relates to diagnostic kits comprising such PNA probes or PN... | 05/08/2012 |
| 8172196 | Supporting device for a mobile colorimeter A device for supporting a mobile calorimeter on a measuring object, especially a monitor, includes a flexible tube-shaped carrying belt (G) which is at least partially filled with a granular loading material and which is provided with a fixing member (1) for ... | 05/08/2012 |
| 8171652 | Penetrable and resealable lyophilization method Device and method for lyophilizing a substance within the device and storing therein the lyophilized substance. The device defines a chamber for receiving therein the substance to be lyophilized, a penetrable and resealable portion of the device is penetrable or pie... | 05/08/2012 |
| 8171595 | Roller for coating a curved surface Disclosed herein is a roller for coating a curved surface. The roller includes a handle and a concave sleeve rotatably mounted thereto. The concave sleeve includes an outer surface that is curved inwardly. The concave sleeve can include an outer layer, such as a fib... | 05/08/2012 |
| D659176 | Hole saw | 05/08/2012 |
| D659027 | Wristwatch | 05/08/2012 |
| D659026 | Wristwatch | 05/08/2012 |
| D659025 | Wristwatch | 05/08/2012 |
| 8168793 | Nitrocatechol derivatives as COMT inhibitors New compounds of formula I are described. The compounds have potentially valuable pharmaceutical properties in the treatment of some central and peripheral nervous system disorders. ... | 05/01/2012 |
| 8168760 | Crystalline anti-human IL-12 antibodies The invention relates to batch crystallization methods for crystallizing an anti-hIL-12 antibody that allows the production of the antibody on an industrial scale, antibody crystals obtained according to the methods, compositions containing the crystals, and methods... | 05/01/2012 |
| 8167847 | Antiseptic cap and antiseptic cap equipped plunger and syringe barrel assembly The present invention provides an antiseptic cap for use with an access site having a housing with a wall defining a chamber, the wall having a set of threads on an inner surface of the wall; and an access site contacting surface associated with the housing having a... | 05/01/2012 |
| 8167143 | Desalination devices and systems using porous hydrophobic hollow fibers and hydrophobic porous coatings DCMD and VMD systems and methods for use in desalination applications are provided. The DCMD and VMD systems employ coated porous hydrophobic hollow fiber membranes. The coatings advantageously function to essentially eliminate pore wetting of the membrane, while pe... | 05/01/2012 |
| D658370 | Bag with corners | 05/01/2012 |
| 8163520 | Nucleic acids encoding a chimeric polypeptide comprising IL-7 and HGF-beta chain and methods of use The present invention relates to a single-chain or chimeric polypeptide comprising a cytokine and a growth factor linked by at least one amino acid residue, and wherein the chimeric polypeptide enhances the proliferation and/or differentiation of hematopoietic precu... | 04/24/2012 |
| 8163251 | Transfer port and method for transferring sterile items A sterile enclosure contains a transfer module defining a window. A port covers the window to maintain the inside of the enclosure as a sealed and sterile environment. A sliding, heated cutting element mounted on the port serves to sterilize and sever a portion of a... | 04/24/2012 |
| 8163216 | Method for producing a film web The invention relates to a method for producing a film web during which an initial film web made of thermoplastic polymer material with a polyethylene matrix, in which 1 to 70 parts by weight of polypropylene, with regard to 100 parts by weight of polyethylene matri... | 04/24/2012 |
| 8162966 | Surgical devices incorporating liquid jet assisted tissue manipulation and methods for their use Surgical instruments are disclosed that utilize high-pressure liquid jets to perform a variety of useful functions. In certain embodiments, surgical instruments are described incorporating one or more liquid jets utilized to contact tissue excised by a non-liquid je... | 04/24/2012 |
| 8162887 | Automatic injection devices An injection device comprises a syringe extendible against a spring bias from a retracted position in a housing to a projecting injecting position. A spring biased plunger has collapsible elbows which, when the plunger is released, initially engage the end of the sy... | 04/24/2012 |
| 8161654 | Four point utility blade and method A utility blade for use with conventional retractable and fixed blade utility knives comprising a blade body having a generally trapezoidal configuration defined by a cutting edge, an opposite back edge, a pair of opposing side edges and a pair of cutting points def... | 04/24/2012 |
| RE43329 | One-way actuation release mechanism for a system for applying medicament A medicament-dispensing system includes a cartridge for housing and actuating an accordion-like vial-dispenser for dispensing a calibrated amount of medicament by means of a single actuation motion which sequentially loads the vial-dispenser and dispenses the loaded... | 04/24/2012 |
| 8158595 | Modular aptamer-regulated ribozymes An extensible RNA-based framework for engineering ligand-controlled gene regulatory systems, called ribozyme switches, that exhibit tunable regulation, design modularity, and target specificity is provided. These switch platforms typically contain a sensor domain, c... | 04/17/2012 |
| 8158594 | CYP1B1 nucleic acids and methods of use The present invention provides nucleic acids containing transcriptional units that encode CYP1B1 polypeptides or portions thereof, wherein the transcriptional units lack sequences found in the untranslated region (UTR) of naturally occurring forms of the CYP1B1 tran... | 04/17/2012 |
| 8158162 | Eutectic-based self-nanoemulsified drug delivery system A eutectic-based self-nanoemulsified drug delivery system (SNEDDS) is formulated from polyoxyl 35 castor oil (Cremophor), medium chain mono- and diglycerides (capmul), essential oils, and a pharmacologically effective drug. The preferred pharmacologically effective ... | 04/17/2012 |
| D657592 | Office table | 04/17/2012 |
| 8155737 | Pharmacokinetics of iontophoretic sumatriptan administration Improved pharmacokinetic profiles for the iontophoretic delivery of sumatriptan are described. ... | 04/10/2012 |
| 8153972 | Infrared camera for locating a target using at least one shaped light source An infrared camera including optics and a detector sensitive to infrared radiation is used in conjunction with at least one light source, such as a laser, to locate a reference point on a target. Two intersecting line segments are produced by the one light source or... | 04/10/2012 |
| 8150706 | Remote prescription refill system A prescription refill system having Voice-over-IP (VoIP) capabilities is provided. A central station remote from a pharmacy is provided for receiving phone calls (e.g., PSTN or VoIP calls) relating to prescription information. The central station obtains the prescri... | 04/03/2012 |
| 8148426 | Bis(thio-hydrazide amides) for increasing Hsp70 expression A method of treating a Hsp70-responsive disorder in a subject includes administering to the subject an effective amount of a compound represented by Structural Formula I, or a pharmaceutically acceptable salt or solvate thereof. ... | 04/03/2012 |