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| Number | Title | Issue Date |
| 7754875 | Halide-free glucosamine base-organic acid salt compositions A salt of a glucosamine base having a purity of at least about 99 wt. % and a maximum halide content of about 0.01 wt. %, and an organic acid. The organic acid that is saltified with the glucosamine base is preferably a hydroxyacid or a ketoacid. Preferably, the sal... | 07/13/2010 |
| 7683042 | Stabilized halide-free glucosamine base and method of preparation A stabilized glucosamine base composition comprising a glucosamine base having a purity level of at least 99.0 wt. % and a maximum halide content of about 0.01 wt. % coated with at least one pharmaceutically acceptable polymer comprising a water-soluble, water-immis... | 03/23/2010 |
| 7662803 | Method for treating warm-blooded vertebrates with halide-free glucosamine-acidic drug complexes A method of treating a warm-blood vertebrate. The vertebrate may be a human being or a lower animal. The treatment method involves administering to the vertebrate in need of such treatment a pharmaceutically effective amount of a complex of halide-free glucosamine a... | 02/16/2010 |
| 7662802 | Halide-free glucosamine-acidic drug complexes A complex of glucosamine having a purity of at least about 99 wt. % and a maximum halide content of about 0.01 wt. %, and a therapeutic drug having a pKa of less than 7. Preferably, the complex is stabilized by coating it with at least one pharmaceuticall... | 02/16/2010 |
| 7622576 | Halide-free glucosamine base and method of preparation A glucosamine base having a pure level of at least about 99.0 wt. % and a maximum halide content of 0.01 wt. %. The pure glucosamine base is prepared by reacting a glucosamine halide, e.g., glucosamine hydrochloride, with a lithium base in the presence of a C1 | 11/24/2009 |
| 7607596 | Process for enhancing the solubility of poorly soluble drugs The solubility/dissolution rate of a poorly soluble drug is enhanced by a process that utilizes a twin-screw extruder containing (i) a feed zone containing a first liquid and powder feed stations; (ii) a grinding/mixing zone containing a second liquid feed port loca... | 10/27/2009 |
| 7511134 | Method for preparing N-acetylglucosamine A method for preparing n-acetylglucosamine starting from glucosamine base having a purity level of at least about 99 wt. % and a maximum halide content of about 0.01 wt %. The glucosamine base is slurried in a diluent comprising a C1-C4 straigh... | 03/31/2009 |
| 7388001 | Halide-free glucosamine sulfate compositions and methods of preparation Glucosamine sulfate having a purity of at least about 99 wt. %, and a maximum halide content of about 0.01 wt. %. Preferably, the glucosamine sulfate is stabilized by coating it with at least one pharmaceutically acceptable polymer comprising a water-soluble, water-... | 06/17/2008 |
| 7388000 | Halide-free glucosamine phosphate compositions and methods of preparation Glucosamine phosphate having a purity of at least about 99 wt. %, and a maximum halide content of about 0.01 wt. %. Preferably, the glucosamine phosphate is stabilized by coating it with at least one pharmaceutically acceptable polymer comprising a water-soluble, wa... | 06/17/2008 |
| 7074459 | Method for preserving wood A method for preserving wood which comprises contacting the wood with a complex of a cationic monomeric or polymeric biocide and an anionic monomeric or polymeric biocide. Insoluble complexes may solubilized in water in the form of an emulsion or microemulsion by ad... | 07/11/2006 |
| 7001886 | Hot melt method for preparing diphenhydramine tannate The invention pertains to a method for preparing diphenhydramine tannate by reacting diphenhydramine free base at a temperature of about 75 to about 150° C. with tannic acid neat or as an aqueous slurry containing up to about 20 wt. % water. The diphenhydramine fre... | 02/21/2006 |
| 6939856 | Method for preparing dexchlor tannate The invention pertains to a method for preparing dexchlorpheniramine (“dexchlor”) tannate by reacting dexchlorpheniramine free base at a temperature of about 75 to about 150° C. with tannic acid neat or as an aqueous slurry containing up to about 20 wt. % water... | 09/06/2005 |
| 6881744 | Carbinoxamine tannate The invention pertains to carbinoxamine tannate and to a method for preparing carbinoxamine tannate by reacting carbinoxamine free base at a temperature of about 50 to about 150° C. with tannic acid neat or as an aqueous slurry containing about 5 to about 30 wt. % ... | 04/19/2005 |
| 6833360 | Process for preparing pseudoephedrine tannate The invention pertains to a method for preparing pseudoephedrine tannate by reacting pseudoephedrine free base at a temperature of about 70 to about 110° C. with tannic acid neat or as an aqueous slurry containing about 5 to about 30 wt. % water. ... | 12/21/2004 |
| 6790959 | Process for manufacturing thebaine Thebaine is manufactured in high yields and with a high purity using codeine or a salt of codeine as the starting material. The manufacturing process involves the following steps: (a) codeine or a codeine salt (e.g., codeine phosphate) is converted into the i... | 09/14/2004 |
| 6689817 | Process for preparing guaifenesin tannate The invention pertains to a process for preparing guaifenesin tannate. The process involves the steps of mixing guaifenesin with tannic acid in the presence of water, continuing to mix the reaction mixture for about 5 minutes to about 4 hours and thereaft... | 02/10/2004 |
| 6677381 | Guaifenesin tannate The invention pertains to a novel composition comprising guaifenesin tannate and to a method for preparing guaifenesin tannate by reacting guaifenesin with tannic acid at a temperature above the melting point of guaifenesin. The guaifenesin tannate has ex... | 01/13/2004 |
| 6670370 | Dextromethorphan tannate The invention pertains to a composition comprising dextromethorphan tannate and to a method for preparing dextromethorphan tannate by reacting dextromethorphan at a temperature of about 80 to about 180° C. with tannic acid either neat or as an aqueous sl... | 12/30/2003 |
| 6524618 | Directly compressible extended-release matrix formulation for metformin hydrochloride An extended-release matrx formulation capable of being directly compressed into tablets comprising metformin hydrochloride blended with specific excipients. The excipients used in the formulation enhance the flow and compaction properties of the drug and ... | 02/25/2003 |
| 6472380 | Glucosamine sulfate calcium chloride composition and processes for the preparation of glucosamine sulfate metal chlorides Glucosamine compositions comprising the compounds glucosamine sulfate metal chloride, wherein the metal, i.e., the cation is potassium, sodium, magnesium, lithium, calcium, zinc or manganese. The compounds have purity levels of at least about 97%, with wa... | 10/29/2002 |
| 6455727 | Process for preparing carbetapentane tannate The invention pertains to a process for preparing carbetapentane tannate. The process involves the steps of heating carbetapentane to a temperature of about 80 to about 120° C. and slowly adding tannic acid to the carbetapentane while agitating the react... | 09/24/2002 |
| 6428616 | Curable coating compositions An aqueous, curable coating composition comprising a mixture of: (a) at least one water soluble alkali metal silicate; and (b) an effective amount of a water-soluble crosslinking agent comprising an alkali metal aluminophosphate, or an alkali metal aluminoborophosp... | 08/06/2002 |
| 6274176 | Herbal compositions and their use as anti-inflammatory agents for alleviation of arthritis and gout An edible composition for use as an anti-inflammatory agent for alleviation of arthritis and gout in mammals. The edible composition is a mixture of at least three, preferably at least seven, herbs selected from the group consisting of Tanacetum partheniu... | 08/14/2001 |
| 6238697 | Methods and formulations for making bupropion hydrochloride tablets using direct compression Methods and formulations for making extended release bupropion hydrochloride tablets using direct compression, and tablets formed thereby, are provided which combine bupropion hydrochloride, binders such as polyethylene oxide or hydroxypropyl cellulose, a... | 05/29/2001 |
| 6162438 | Herbal compositions and their use as agents for control of hypertension, hypercholesterolemia and hyperlipidemia Edible herbal compositions for use as agents for the control of hypertension, hypercholesterolemia and hyperlipidemia in mammals. The edible composition is a mixture of at least three, preferably at least six, herbs selected from the group consisting of T... | 12/19/2000 |
| 6153375 | Method of making a library of compounds using a functionalized polymer support resin affixed to a laminar material The instant invention is directed to a method of making a library of compounds using a segmentable support material comprised of a particulate resin affixed to a porous laminar material.... | 11/28/2000 |
| 5902801 | Glucosamine sulfate metal chloride compositions and process of preparing same Glucosamine compositions comprising the compounds glucosamine sulfate metal chloride, wherein the metal, i.e. the cation, is lithium, sodium, magnesium, zinc or manganese. The compounds have purity levels of at least about 97%, with water present in a max... | 05/11/1999 |
| 5900240 | Herbal compositions and their use as hypoglycemic agents An edible composition comprising a mixture of at least two herbs selected from the group consisting of Syzygium cumini, Gymnema sylvestre, Momordica charantia and Solanum melongena. Preferably, the composition comprises a mixture of Syzygium cumini and Mo... | 05/04/1999 |
| 5843923 | Glucosamine sulfate potassium chloride and process of preparation thereof A composition comprising the compound glucosamine sulfate potassium chloride having a purity level of at least about 97% and water present in a maximum amount of about 10 wt. %, based on the weight of the composition. The compound is prepared by contactin... | 12/01/1998 |
| 5705103 | Composition for producing chemiluminescent light of controllable duration A chemiluminescent composition comprising an oxalate component comprising polystyrene or homopoly--methylstyrene containing an oxalate ester; an activator component comprising a solution of a peroxide compound and a catalyst in a first solvent; and... | 01/06/1998 |
| 5637681 | Aminosaccharide biguanides Novel aminosaccharide biguanides are prepared by either reacting a aminosaccharide with a mono- or multi-functional cyanoguanidine or by reacting a monocyano-guanidine of an aminosaccharide with a mono- or multi-functional primary and/or secondary amine. ... | 06/10/1997 |
| 5609981 | Waterless presensitized printing plate comprising four layers and method of making thereof A camera speed lithographic plate precursor composition is used for the preparation of waterless, imaged printing plates. The plates comprise a solid substrate with a first layer of a photopolymerizable, oleophilic coating; a second layer of silicone rubb... | 03/11/1997 |
| 5599846 | Phenylephrine tannate compositions Phenylephrine tannate compositions are disclosed wherein the phenylephrine tannate has a minimum purity level of at least 95%. The composition also contains a minor amount of water, but no significant quantities of organic compounds or solvents other than... | 02/04/1997 |
| 5597517 | Two-component chemiluminescent composition A chemiluminescent composition comprising an oxalate component comprising an oxalate ester and a solvent, an activator component comprising a peroxide compound and a catalyst and a fluorescer contained in the oxalate component and/or the activator compone... | 01/28/1997 |
| 5589323 | Chemically stable ascorbate-based photographic developer and imaging process The invention comprises a process for forming a high contrast photographic image including the steps of imagaewise exposing a silver halide photographic element containing a hydrazine compound which functions as a nucleating agent, wherein the element is ... | 12/31/1996 |
| 5575843 | Process for improving color value of a pigment A process for improving the color value of a pigment and for imparting stability to a water-based printing ink containing such pigment which comprises adding a polyester or polyether to the strike tank during the pigment conditioning step; the preferred p... | 11/19/1996 |
| 5567747 | Water-based printing ink The invention relates to a water-based oxidizing printing ink especially suited for flexographic printing. The ink comprises an epoxy ester resin, an inorganic and/or organic pigment, a drier, a cyclodextrin and water. Preferably, the ink also includes a ... | 10/22/1996 |
| 5552467 | Vegetable oil based thermosetting lithographic ink system Rapid thermosetting, low VOC web offset lithographic inks are prepared in the instant invention from solid resin, drying oil alkyds, bodied drying oil, vegetable oil, fatty acids, multifunctional unsaturated polyester, reducing agents and transition metal... | 09/03/1996 |
| 5551585 | Process for the surface treatment of lithographic printing plate precursors A process is disclosed to produce a fine honeycomb grain with matte finishing on an aluminum surface in alkaline solution with or without electrical treatment. To achieve the fine honeycomb, a passivation enhancement step is used prior to alkaline etching... | 09/03/1996 |
| 5512420 | Waterless presensitized plate comprising four layers A camera speed lithographic plate precursor composition is used for the preparation of waterless, imaged printing plates. The plates comprise a solid substrate with a first layer of a photopolymerizable, oleophilic coating; a second layer of silicone rubb... | 04/30/1996 |
