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Attorney: Martin; Timothy J., Henson; Michael R., Weygandt; Mark H.


Number of patents: 56
Last date: November 12, 2002

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NumberTitleIssue Date
6479679Two-step conversion of protected taxane ester to paclitaxel
The present invention relates to a method of producing paclitaxel from a protected coupled ester compound having a formula: ##STR1## wherein P1 is a hydrogenatable protecting group, comprising the steps of deprotecting the 7-O-position, 3'-N-po...
11/12/2002
6461376Tanning apparatus and handle for use therewith
A tanning apparatus with first and second tanning units movable between an open position to provide access to an interior and a closed position to enclose the interior and define a tanning chamber. Ultraviolet lamps are supported on one of the tanning uni...
10/08/2002
6452025Three-step conversion of protected taxane ester to paclitaxel
The present invention relates to a method of producing paclitaxel from a protected coupled ester compound having a formula: ##STR1## wherein P1 is a hydrogenatable protecting group, comprising deprotecting the 7-O-position and 3'-N-position of ...
09/17/2002
6448417Methods and useful intermediates for paclitaxel synthesis from C-7, C-10 di-cbz 10-deacetylbaccatin III
The present invention relates to a method of producing paclitaxel or a paclitaxel analog comprising the esterification of C-7, C-10 di-CBZ 10-deacetylbaccatin III with an N-carbamate protected, C-2-protected 3-phenyl isoserine side chain. The C-7, C-10 ca...
09/10/2002
6440391Management of snoring by oral administration of dimethyl sulfone
A method of managing snoring is provided by the instillation orally of a solution containing 1-20% methylsulfonylmethane by weight dissolved in water so as to cover the mucous membranes of the orophyrnx. Preferably, the solution has between 10%-15% by wei...
08/27/2002
6436149Artificial ankle joint and prosthetic devices formed therewith
A prosthetic device is provided having a proximal end portion adapted to be secured to an amputee and a distal foot structure. The improvement comprises a pivoting ankle joint disposed between the proximal end portion and the foot structure. This ankle jo...
08/20/2002
6435016Head gimbal assembly, test device and slider for use therewith
A slider for use during production of a rigid memory disk comprises a rigid body fabricated from a single phase material having a fracture toughness greater than 4 MPam0.5. A head gimbal assembly and a test device are also provided. The head gi...
08/20/2002
6431606Memory album
A memory album retains and displays items of memorabilia and comprises top and bottom covers, which may be constructed of a stiff backing material and have a selected geometric configuration, and a foldable display panel disposed between the covers for re...
08/13/2002
6398235Mobile storage unit
A mobile storage unit broadly comprises a support frame, primary and auxiliary wheel assemblies, and first and second storage shelves. The primary wheel assembly assists to position the support frame upright on a transport surface and permits movement of ...
06/04/2002
6393877Security support system to display items
A security support system and method adapted to display an item on a support surface having spaced apart parallel channels to lockably retain the item against unauthorized removal. The security support system includes a base member that is sized and confi...
05/28/2002
6388573Motion detection system and methodology for accomplishing the same
A motion detection system for detecting an object's movement through a threshold in a selected direction comprises first and second transmitters for producing respective broadcast signals across the threshold along respective transmission paths, a receive...
05/14/2002
6367706Fragrance extending device and method therefor
A fragrance extender releases fragrance from a fragrance producing composition over a prolonged interval of time. The fragrance includes a piece of ceramic material of sufficient porosity to permit penetration of the fragrance emitting substance and the c...
04/09/2002
6361602Apparatus for lubricating the exterior surface of an item as a strip of material
A coating station for an apparatus and method used to coat at least one side of a pontinuous strip of material includes a housing having a conduit that connects to a source of coating material, a fluid dispensing passageway and a wick that contacts the st...
03/26/2002
6349957Shock absorber for cycle and methodology incorporating the same
A shock absorber for use with a cycle comprises elongated first and second tubular members and a biasing assembly. The first tubular member is associated with the cycle's frame and has a longitudinal axis. The second tubular member has a lower end portion...
02/26/2002
6309092Illumination device for illuminating an object's interior
An illumination device is adapted to be placed in an interior of an object to illuminate a surrounding area, and comprises a housing, a light source and a decorative skirt. The housing has an interior sized and adapted to receive an electric power supply,...
10/30/2001
6281368Simple and efficient hydrazinolysis of C-10 and C-13 ester functionalities of taxanes to obtain 10-DAB III
A process for producing 10-deacetyl baccatin III from an acidic solution containing a spectrum of taxanes, comprising contacting the acidic solution containing the spectrum of taxanes with a hydrazine hydrate, thereby to convert into 10-deacetyl baccatin ...
08/28/2001
6269774Receptacle adapted to receive a plant and provide a sheltered habitat for a living creature
An apparatus for receiving a plant and providing a habitat for a living creature is comprised of a housing having an interior defined by a bottom portion and a surrounding sidewall that extends upwardly from the bottom portion. A divider disposed in the h...
08/07/2001
6266186Creative art kit for producing and viewing stereoscopic creative art images
A creative art kit is provided for producing and viewing stereoscopic images. The kit includes a pigmented medium that is adapted to be applied to a surface and which includes a luminescent material as a component thereof. The kit also includes a viewer t...
07/24/2001
6262281Syntheses of taxol, taxol analogs and their intermediates with variable A-ring side chain structures and compositions thereof
The present invention relates to chemical compounds that are useful in the production of taxanes. The chemical compounds according to the present invention have a generalized formula: ##STR1## wherein R1 is NH2, and wherein R2
07/17/2001
6260480Egg cleaning and decorating method and kit therefor
An egg cleaning kit is provided for removing contents of a raw egg from the interior of a shell so that the shell's exterior surface may be decorated. The kit includes a hole-former for producing an opening through the shell, and an injector including a n...
07/17/2001
6219888Anchor device
An anchor device is provided to engage a segment of a cord. The anchor device has a main body portion and a pair of opposed jaw portions that extend from the body in spaced-apart relationship to one another thereby to form a cavity with a rear wall. A ret...
04/24/2001
6206396Cycle incorporating shock absorber
A cycle adapted to travel in an upright position along a support surface comprises a rigid frame, a plurality of wheels rotatably journaled with respect to the frame, a suspension tube mounted to the frame for reciprocal movement in upward and downward di...
03/27/2001
6199232Emergency care blanket
An emergency care blanket may be assembled into a plurality of desired arrangements to protect an individual from prevailing environmental conditions while providing access to the patients. Broadly the blanket includes a first flexible covering, a second ...
03/13/2001
6186530Trailer hitch and extension coupling for use therewith
An extension coupling releasably interconnects a trailer to a tow hitch on a tractor vehicle. The apparatus includes a trailer mounting assembly adapted to releasably interconnect to the trailer. The trailer mounting assembly includes a hitch box mount ad...
02/13/2001
6163504Signal detector and methodology for monitoring sound signals having frequencies over a selected frequency range
A signal detector for monitoring sound signals comprises a first sensor operative in response to sound signals to produce a first electrical signal, first processing circuitry operative in response to the first electrical signal to amplify it and produce ...
12/19/2000
6143902C-2 hydroxyl protected-N-acyl (2R,3S)-3-phenylisoserine N-imido activated esters and method for production thereof
A chemic compound having the formula: ##STR1## wherein P1 is a hydroxyl protecting group, R1 is an alkyl group, an olefinic group, an aromatic group, Ph, PhCH2, an O-alkyl group, an O-olefinic group, an O-aromatic gro...
11/07/2000
6136999C-2 hydroxyl protected-n-acyl (2R,3S)-3-phenylisoserine substituted phenyl activated esters and method for production thereof
A chemical compound having the formula: ##STR1## wherein P1 is a hydroxyl protecting group, R1 may be H or electron withdrawing group, R2 may be H or electron withdrawing group, R3 may be H or electron with...
10/24/2000
6135984Cannula for use in corrective laser eye surgery
A cannula for use in conjunction with a fluid source to irrigate a corneal surface of an eye, comprises a connector adapted to attach to the fluid source; and an elongated, hollow prong element having a proximal end supported by said connector and a dista...
10/24/2000
6133462C-7 CBZ baccatin III and production method therefor
A compound for use in the production of taxanes and intermediates therefor having the formula: ##STR1## wherein R is an alkyl group....
10/17/2000
6125487Infant support cushion
A cushion supports an infant on a support surface, especially as an aid in changing the infant's diapers and garments. The cushion includes an inner elongated pad that is preferably formed as two sections of foam material. The upper surface of the pad is ...
10/03/2000
6112401Methodology for fabricating sliders for use in glide head devices
A method is provided for fabricating a slider out of a production piece slider blank so that the slider may be used in a glide head assembly that is operative with a test system to detect a presence of asperities on a moving surface. Broadly, this method ...
09/05/2000
6109399Brake shoe and production method therefor
The present invention is directed to a brake shoe adapted for use in a braking mechanism that comprises a support member and a substantially metal free brake pad disposed on the support member. The brake pad may be composed of polymerized urethane as a ma...
08/29/2000
6107497Intermediate for use in docetaxel synthesis and production method therefor
C7, C10 di-CBZ 10-deacetyl baccatin III of the formula: ##STR1## provides an intermediate for the production of docetaxel. A method of producing this C7, C10 di-CBZ 10-deacetyl Baccatin III is provided. Here, 10-deacetyl Baccatin III is acylated with...
08/22/2000
6102631Drill attachment
An open ended cylindrical drill attachment for attachment on a drill bit to collect dust while drilling. The drill attachment having an inner structure formed of vanes extending from inner walls to slightly offset the center, to form a central channel for...
08/15/2000
6099892Protective coating for decorative vegetable material
The present invention is directed to a composition adapted to be applied to coat a surface area of a vegetable in order to retard environmental degradation thereof. The composition comprises a film-former, a fungicide and a thickener distributed in a carr...
08/08/2000
6093446Method for decorating surfaces with transfer patterns
The present invention provides a method of decorating a surface of an item that has an area adapted to display a design. The method comprises spreading onto the area a quantity of a viscous surface preparatory composition that has an initial first state t...
07/25/2000
6093070Man overboard device
A rescue device, and man overboard device for use therewith, is adapted for use with a ship to rescue individuals floating at sea and may comprise a lifting crane, and a plurality of fasteners, rope-like elements and connectors. The lifting crane includes...
07/25/2000
6088008Apparatus and method for remotely controlled variable message display
A variable message display sign comprises a plurality of interchangeable character displays each having a plurality of signal elements organized in distinct sets, with each signal element having an on state and an off state. A controller is located remote...
07/11/2000
6084011Freeze/thaw resistant cementitious adhesive for composite materials and method for production thereof
A cementitious paste capable of setting after an interval of time comprises a mixture of a fines component selected from a group consisting of cement and a blend of cement and pozzolonic material, water and a water soluble polymer that is capable of takin...
07/04/2000
6079275Signal detection instrument with touch probe resonator assembly for use therewith
A resonator assembly adapted for use with a signal detection instrument includes a sensor operative to detect airborne sound signals and a touch rod. The resonator assembly operates to convert sound signals traveling within the touch rod into the airborne...
06/27/2000
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