...that the video game, Pong, was invented by a guy who graduated at the bottom of his engineering class? Nolan Bushnell spent more time running the games at a local amusement park than he did on his studies at the University of Utah. His dreams of working for Disney's amusement empire were dashed when the company wouldn't hire him. Taking a boring job, Nolan daydreamed about electronic versions of popular games. He invented Pong, the first video game, and went on to found Atari Co.
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| Number | Title | Issue Date |
| 7569551 | Chemo- and radiation-sensitization of cancer by antisense TRPM-2 oligodeoxynucleotides Administration of antisense oligodeoxynucleotides (ODN) targeted against the testosterone-repressed prostate message-2 (TRPM-2) gene can reduce the amount of TRPM-2 in renal cell cancer (RCC) cells and other cancer cells, and as a result enhance chemosensitivity of ... | 08/04/2009 |
| 7534773 | TRPM-2 antisense therapy Antisense therapy which reduces the expression of TRPM-2 provides therapeutic benefits in the treatment of cancer for example prostate cancer and renal cell cancer. Antisense TRPM-2 ODN treatment of prostatic tumor cells in vivo is effective for delaying the onset o... | 05/19/2009 |
| RE40697 | Method for making an aromatic polycarbonate This invention relates to an extrusion method preparing polycarbonates from a solution of an oligomeric polycarbonate. A mixture of bis(methyl salicyl)carbonate (BMSC), BPA and a transesterification catalyst are first equilibrated at moderate temperatures to provide... | 04/07/2009 |
| 7498400 | Method of preparing polycarbonate Polycarbonates incorporating terminal carbonate groups derived from ester-substituted activated carbonates in a transesterification process have unfavorable properties with respect to color, hydrolytic stability and thermal stability, particularly when the polycarbo... | 03/03/2009 |
| 7488764 | Polymer encapsulation of high aspect ratio materials and methods of making same A pigment contains one or more substantially spherical-shaped beads. Each substantially spherical-shaped bead includes one or more high aspect ratio particles encapsulated within an encapsulating material. Resinous compositions containing this pigment and a plastic,... | 02/10/2009 |
| 7485695 | Polycarbonates containing low levels of methyl salicylate prepared by a melt polymerization in a reactive extruder Polycarbonate is prepared by reactive extrusion on a reactive extruder. A method incorporates the steps of introducing a polycarbonate oligomer, an activated carbonate, and a transesterification catalyst to the extruder through a feed section. The extruder has a fee... | 02/03/2009 |
| 7485694 | Polycarbonates containing low levels of methyl salicylate prepared by a melt polymerization in a reactive extruder Polycarbonate is prepared by reactive extrusion on a reactive extruder. A method incorporates the steps of introducing a polycarbonate oligomer, an activated carbonate residue, and a transesterification catalyst to the extruder through a feed section. The extruder h... | 02/03/2009 |
| 7482423 | Polycarbonates and method of preparing same Polycarbonates incorporating terminal carbonate groups derived from ester-substituted activated carbonates, for example terminal methyl salicyl carbonate (TMSC) derived from the use of BMSC as the activated carbonate in a transesterification process, have unfavorabl... | 01/27/2009 |
| 7470732 | Polymer encapsulation of high aspect ratio materials and methods of making same A pigment contains one or more substantially spherical-shaped beads. Each substantially spherical-shaped bead includes one or more high aspect ratio particles encapsulated within an encapsulating material. Resinous compositions containing this pigment and a plastic,... | 12/30/2008 |
| 7456418 | RF-enablement of auditable storage for hazardous materials A cementitious container that has a low-frequency radio tag containing the container's pedigree and history. The container is used for storage of hazardous waste are disclosed having an inner layer of substantially unhydrated cement in contact with the hazardous was... | 11/25/2008 |
| 7446190 | Nucleic acids encoding chimeric T cell receptors Chimeric T cell receptors (TCR) are provided that combine, in a single chimeric species, the intracellular domain of CD3 ζ-chain, a signaling region from a costimulatory protein such as CD28, and a binding element that specifically interacts with a selected target.... | 11/04/2008 |
| 7438694 | Lancing device A lancing device is used with a lancet for lancing body tissue to result in a wound for bleeding. An improved lancing device has a priming knob having a slanted priming notch rotatably connected to the lancing device about an axis of rotation generally parallel to a... | 10/21/2008 |
| 7439359 | Small molecule compositions for binding to hsp90 Structural differences in binding pockets of members of the HSP90 family can be exploited to achieve differential degradation of kinases and other signaling proteins through the use of designed small molecules which interact with the N-terminal binding pocket with a... | 10/21/2008 |
| 7436304 | Evidence tracking A system uses a large loop antenna, connected with a transceiver operating below 1 MHz. The loop antenna is deployed from a spool to surround a crime scene, and may carry indicia communicating that it is a crime scene boundary. The system interrogates devices, inclu... | 10/14/2008 |
| 7429649 | Modification of lignin biosynthesis The present invention relates to the modification of lignin biosynthesis in plants, using the nucleotide sequences encoding the enzymes 4-coumarate CoA-ligase (4CL), cinnamoyl-CoA reductase (CCR), cinnamyl alcohol dehydrogenase (CAD) of the lignin biosynthetic pathw... | 09/30/2008 |
| 7393896 | Impact modified carbonate polymer composition having improved resistance to degradation and improved thermal stability An aromatic carbonate polymer composition having improved thermal stability consisting of an aromatic carbonate polymer such as a polycarbonate or polycarbonate/polyester blend and an impact modifier which is free of alkali materials which catalytically degrade a po... | 07/01/2008 |
| 7372277 | Method and apparatus for providing stable voltage to analytical system An electrochemical cell has two terminals. One of the terminals is connected to a pulse-width-modulated (PWM) power supply and to a voltmeter. The other terminal is connected to circuitry capable of switching between amperometric and potentiometric measurement modes... | 05/13/2008 |
| 7368436 | TRPM-2 antisense therapy It has been determined that antisense therapy which reduces the expression of TRPM-2 provides therapeutic benefits in the treatment of cancer, particularly prostate and renal cell cancers. Addition of antisense TRPM-2 ODN to prostatic tumor cells in vi... | 05/06/2008 |
| 7365149 | Equipment cleaning in the manufacture of polycarbonates A surface of a melt polymerization reactor system having residual reaction components of a melt polymerization reaction thereon can be cleaned by introducing a cleaning agent having a phenolic compound to the polymerization reactor system and into contact with the s... | 04/29/2008 |
| 7344626 | Method and apparatus for detection of abnormal traces during electrochemical analyte detection Detection of abnormal signal traces in electrochemical measurements generated using an electrochemical test strip to which a potential is applied allows for an indication of an erroneous analyte determination. The current trace has an expected shape in which a peak ... | 03/18/2008 |
| 7345116 | Clear polycarbonate polyester blend An optically clear thermoplastic resin composition is disclosed which comprises structural units derived from substituted or unsubstituted polycarbonate and substituted or unsubstituted polyester, wherein said polyester comprises structural units derived from tereph... | 03/18/2008 |
| 7322461 | Guide rail for stairlifts The present invention provides a stairlift rail of non-circular cross-section. The wall surfaces of the rail define a single internal cavity and the outer surface of the rail is free of additional members added to the rail in order to prevent rotation of a stairlift... | 01/29/2008 |
| 7312352 | Method of preparing ester-substituted diaryl carbonates The present invention relates to an interfacial method of preparing ester-substituted diaryl carbonates. The method includes the steps of: forming a reaction mixture comprising phosgene, an ester-substituted phenol, an organic solvent, and a catalyst selected from t... | 12/25/2007 |
| 7309730 | Modified weatherable polyester molding composition A composition formed from (a) a polyester and polycarbonate blend; (b) an organopolysiloxane-polycarbonate block copolymer; (c) an acrylic core shell impact modifier; (d) titanium dioxide and (e) a flame retarding amount of a halogenated flame retardant has properti... | 12/18/2007 |
| 7297684 | Antisense therapy for hormone-regulated tumors A method is provided for treating hormone-regulated tumors (for example, breast and prostatic tumors) in mammals, including humans, by administration of an antisense ODN which is complementary to a portion of the gene encoding IGFBP-5. Using the Shionogi tumor model... | 11/20/2007 |
| 7297409 | Multilayer, weatherable compositions and method of manufacture thereof A weatherable composition comprising an upper layer that comprises a polymer system consisting essentially of a cycloaliphatic polyester resin, and an additive composition comprising an hindered amine light stabilizer and a low volatility, hydroxyphenyl triazine or ... | 11/20/2007 |
| 7285541 | Treatment of melanoma by reduction in clusterin levels Treatment of melanoma is achieved through reduction in the effective amount of clusterin in melanoma cells of in a mammalian subject, preferably a human. A therapeutic agent effective to reduce the effective amount of clusterin in the melanoma cells is administered ... | 10/23/2007 |
| 7278762 | Automotive headlamps with improved beam chromaticity Lenses for lamps can improve the quality of the light emitted through lens by interacting with the light bulb. Photoluminescent dyes as well as non-photoluminescent dyes may be incorporated into a polycarbonate lens in order to shift the chromaticity of the light so... | 10/09/2007 |
| 7271160 | Methods and compositions for degradation and/or inhibition of HER-family tyrosine kinases Bifunctional molecules comprising two hsp-binding moieties which bind to hsp90 in the pocket to which ansamycin antibiotics bind connected via a linker are effective for inducing the degradation and/or inhibition of HER-family tyrosine kinases. For example, a... | 09/18/2007 |
| 7267951 | Method for evaluating a tissue or biopsy sample to determine if the sample is early-stage melanoma A tissue or biopsy sample is evaluated to determine if the sample is early-stage melanoma by determining the level of inhibitor of DNA-binding protein 1 (Id1) expression in cells of the sample; and comparing the determined amount of Id1 to a reference level. The pre... | 09/11/2007 |
| 7259223 | Process for the production of polycarbonate A process for the production of polycarbonate having increased end-cap levels, the process comprising adding a terminal blocking agent of the formula: wherein R1 is a propoxy o... | 08/21/2007 |
| 7256228 | Stabilized polycarbonate polyester composition A stabilized thermoplastic resin composition is disclosed which comprises structural units derived at least one substituted or unsubstituted polycarbonate, at least one substituted or unsubstituted polyester and a combination of at least two quenchers, wherein said ... | 08/14/2007 |
| 7253230 | Method of manufacture of polyester molding compositions and articles produced therefrom A thermoplastic molding composition comprises a resin composition having 50 to about 90 weight percent of a polyester, about 8 to about 48 weight percent of a polyetherimide, about 2 to about 25 weight percent of a high rubber graft impact modifier, each based on th... | 08/07/2007 |
| 7247719 | Primers and probes for amplification and detection of human inhibitor of DNA-binding Oligonucleotide primers and polynucleotide probes provide selective amplification and detection of Id genetic sequences and are selected both (1) to provide the desired specificity so that they amplify only the specific Id type to which they are targeted; and (2) to... | 07/24/2007 |
| 7238682 | Methods and compositions for degradation and/or inhibition of HER-family tyrosine kinases Bifunctional molecules comprising two hsp-binding moieties which bind to hsp90 in the pocket to which ansamycin antibiotics bind connected via a linker are effective for inducing the degradation and/or inhibition of HER-family tyrosine kinases. For example, a compou... | 07/03/2007 |
| D545438 | Analyte meter | 06/26/2007 |
| 7232865 | Transparent and high-heat polycarbonate-polysiloxane copolymers and transparent blends with polycarbonate and a process for preparing same A method is provided for making siloxane polycarbonate copolymers and blends of other polycarbonates with such copolymers wherein the copolymers and blends have excellent transparency and physical characteristic. ... | 06/19/2007 |
| 7232854 | Polycarbonate compositions with thin-wall flame retardance Polycarbonate compositions containing a specific combination of additives achieve desirable flame retardance characteristics when used in thin wall polycarbonate articles. These compositions contain a polycarbonate/siloxane component, containing a polycarbonate silo... | 06/19/2007 |
| 7230066 | Polycarbonate—ultem block copolymers The present invention provides novel block copolycarbonates comprising residues from a hydroxy terminated polyetherimide or polyimide, residues from a dihydroxy compound, and residues from an activated carbonate. In a preferred embodiment of the present invention th... | 06/12/2007 |
| 7211562 | Methods for enhancing the efficacy of cytotoxic agents through the use of HSP90 inhibitors The administration of cytotoxic agents followed by the administration of heat shock protein 90 inhibitors, such as ansamycins, has a synergistic effect on the growth inhibition of cells. This synergy occurs at doses of each cytotoxic agent that normally only causes ... | 05/01/2007 |