Did You Know...
...that the video game, Pong, was invented by a guy who graduated at the bottom of his engineering class? Nolan Bushnell spent more time running the games at a local amusement park than he did on his studies at the University of Utah. His dreams of working for Disney's amusement empire were dashed when the company wouldn't hire him. Taking a boring job, Nolan daydreamed about electronic versions of popular games. He invented Pong, the first video game, and went on to found Atari Co.
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| Number | Title | Issue Date |
| 8097452 | Human orphan G protein-coupled receptors The invention disclosed in this patent document relates to transmembrane receptors, more particularly to endogenous, human orphan G protein-coupled receptors. ... | 01/17/2012 |
| RE42954 | Method for repairing a defect in an intervertebral disc Provided herein are methods and devices for inducing the formation of functional replacement nonarticular cartilage tissues and ligament tissues. These methods and devices involve the use of osteogenic proteins, and are useful in repairing defects in the larynx, tra... | 11/22/2011 |
| 7972813 | Tetrodotoxin-resistant sodium channel alpha subunit The present invention is directed to a chimp sodium channel alpha subunit and methods and compositions for making and using the same. ... | 07/05/2011 |
| 7919523 | Inhibitors of aspartyl protease The present invention relates to a novel class of sulfonamides which are aspartyl protease inhibitors. In one embodiment, this invention relates to a novel class of HIV aspartyl protease inhibitors characterized by specific structural and physicochemical features. T... | 04/05/2011 |
| RE42190 | Method of identifying a compound for inhibiting or stimulating human G protein-coupled receptors The invention disclosed in this patent document relates to transmembrane receptors, more particularly to endogenous, human orphan G protein-coupled receptors. ... | 03/01/2011 |
| 7893235 | Nucleic acids encoding the GPCR, RUP3, and methods of use thereof The invention disclosed in this patent document relates to transmembrane receptors, more particularly to endogenous, human orphan G protein-coupled receptors. ... | 02/22/2011 |
| 7816492 | Human G protein-coupled receptors The invention disclosed in this patent document relates to transmembrane receptors, more particularly to endogenous, human orphan G protein-coupled receptors. ... | 10/19/2010 |
| 7803369 | Devices and method for repair of larynx, trachea, and other fibrocartilaginous tissues Provided herein are methods and devices for inducing the formation of functional replacement nonarticular cartilage tissues and ligament tissues. These methods and devices involve the use of osteogenic proteins, and are useful in repairing defects in the larynx, tra... | 09/28/2010 |
| 7632826 | Use of agonists of the glucocorticosteroid and/or mineralo-corticosteroid receptors, in particular corticosteroids for the treatment of addiction Corticosteroid receptors and/or mineralo-corticoid receptors are administered in combination with an addictive drug or the pharmacodynamic equivalent thereof for the therapy of an addictive disease triggered by said addictive drug or connected thereto. ... | 12/15/2009 |
| 7608632 | Sulfonamide inhibitors of aspartyl protease The present invention relates to a novel class of sulfonamides which are aspartyl protease inhibitors. In one embodiment, this invention relates to a novel class of HIV aspartyl protease inhibitors characterized by specific structural and physicochemical features. T... | 10/27/2009 |
| 7592368 | Sulphonamide derivatives as prodrugs of aspartyl protease inhibitors The present invention relates to prodrugs of a class of sulfonamides which are aspartyl protease inhibitors. In one embodiment, this invention relates to a novel class of prodrugs of HIV aspartyl protease inhibitors characterized by favorable aqueous solubility, hig... | 09/22/2009 |
| 7572440 | Method for repairing a defect in an intervertebral disc Provided herein are methods and devices for inducing the formation of functional replacement nonarticular cartilage tissues and ligament tissues. These methods and devices involve the use of osteogenic proteins, and are useful in repairing defects in the larynx, tra... | 08/11/2009 |
| 7524817 | Therapies for chronic renal failure The present invention provides methods for the treatment, and pharmaceuticals for use in the treatment, of mammalian subjects in, or at risk of chronic renal failure, or at risk of a need for renal replacement therapy. The methods involve the administration of certa... | 04/28/2009 |
| 7507709 | Synergistic effects of OP/BMP morphogens and GDNF/NGF neurotrophic factors OP/BMP morphogen may be combined with GDNF/NGF neurotrophic factors to promote the survival or growth, or inhibit the death or degeneration, of mammalian cells, particularly neural cells, which express OP/BMP-activated serine/threonine kinase receptors and GDNF/NGF-... | 03/24/2009 |
| 7419967 | Sulfonamide inhibitors of aspartyl protease The present invention relates to a novel class of sulfonamides which are aspartyl protease inhibitors. In one embodiment, this invention relates to a novel class of HIV aspartyl protease inhibitors characterized by specific structural and physicochemical features. T... | 09/02/2008 |
| 7410947 | Osteogenic devices and methods of use thereof for repair of endochondral bone and osteochondral defects Disclosed herein are improved osteogenic devices and methods of use thereof for repair of bone and cartilage defects. The devices and methods promote accelerated formation of repair tissue with enhanced stability using less osteogenic protein than devices in the art... | 08/12/2008 |
| 7390498 | Method of forming bone with porous βtricalcium phosphate granules A porous β-tricalcium phosphate material for bone implantation is provided. The multiple pores in the porous TCP body are separate discrete voids and are not interconnected. The pore size diameter is in the range of 20-500 μm, preferably 50-125 μm. The porous β-... | 06/24/2008 |
| 7357941 | Method of delivering a bioactive agent with porous β-tricalcium phosphate granules A porous β-tricalcium phosphate material for bone implantation is provided. The multiple pores in the porous TCP body are separate discrete voids and are not interconnected. The pore size diameter is in the range of 20-500 μm, preferably 50-125 μm. The porous β-... | 04/15/2008 |
| 7321063 | Sulfonamide inhibitors of aspartyl protease The present invention relates to a novel class of sulfonamides which are aspartyl protease inhibitors. In one embodiment, this invention relates to a novel class of HIV aspartyl protease inhibitors characterized by specific structural and physicochemical features. T... | 01/22/2008 |
| 7247717 | Polynucleotide encoding a novel human serpin secreted from lymphoid cells, LSI-01 The present invention provides novel polynucleotides encoding LSI-01 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relat... | 07/24/2007 |
| 7041641 | Osteogenic devices and methods of use thereof for repair of endochondral bone and osteochondral defects Disclosed herein are improved osteogenic devices and methods of use thereof for repair of bone and cartilage defects. The devices and methods promote accelerated formation of repair tissue with enhanced stability using less osteogenic protein than devices in the art... | 05/09/2006 |
| 7026292 | Compositions and therapeutic methods using morphogenic proteins and stimulatory factors The present invention provides pharmaceutical compositions comprising a morphogenic protein stimulatory factor (MPSF) for improving the tissue inductive activity of morphogenic proteins, particularly those belonging to the BMP protein family. Methods for improving t... | 04/11/2006 |
| 7022686 | A1 adenosine receptro antagonists Compounds of Formula I and II are disclosed as antagonists of subtype A1 adenosine receptors. These compounds are useful for treatment of various diseases and disorders, including systemic hypertension, renal failure, diabetes, asthma, an edematous condition, conges... | 04/04/2006 |
| 6987021 | Methods and compositions for identifying morphogenic protein analogs using morphogenic protein responsive inhibitory elements The present invention relates generally to methods and compositions for identifying morphogenic protein analogs. In one embodiment, this invention relates to an osteogenic protein reponsive transcription inhibitory element. This invention also relates to the identif... | 01/17/2006 |
| 6958149 | Repair of larynx, trachea, and other fibrocartilaginous tissues Provided herein are methods and devices for inducing the formation of functional replacement nonarticular cartilage tissues and ligament tissues. These methods and devices involve the use of osteogenic proteins, and are useful in repairing defects in the larynx, tra... | 10/25/2005 |
| 6846906 | Modified proteins of the TGF-β superfamily, including morphogenic proteins The invention provides modified proteins and DNAs of the TGF-β superfamily including modified morphogenic proteins. The proteins of the present invention display altered biological or biochemical attributes. Specifically, the modified proteins are designed through ... | 01/25/2005 |
| 6838474 | Sulphonamide derivatives as prodrugs of aspartyl protease inhibitors The present invention relates to prodrugs of a class of sulfonamides which are aspartyl protease inhibitors. In one embodiment, this invention relates to a novel class of prodrugs of HIV aspartyl protease inhibitors characterized by favorable aqueous solubility, hig... | 01/04/2005 |
| 6720335 | Sulfonamide inhibitors of aspartyl protease The present invention relates to a novel class of sulfonamides which are aspartyl protease inhibitors. In one embodiment, this invention relates to a novel class of HIV aspartyl protease inhibitors characterized by specific structural and physicochemical features. T... | 04/13/2004 |
| 6677432 | Mutations of the C-terminal portion of TGF-ଲ superfamily proteins The invention provides modified proteins and DNAs of the TGF-ଲ superfamily including modified morphogenic proteins. The proteins of the present invention display altered biological or biochemical attributes. Specifically, the modified proteins are d... | 01/13/2004 |
