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A sealed crustless sandwich for providing a convenient sandwich without an outer crust which can be stored for long periods of time without a central filling from leaking outwardly.
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| Number | Title | Issue Date |
| 4871548 | Controlled release dosage form comprising different cellulose ethers A dosage form is disclosed comprising a low number average molecular weight hydroxypropylmethylcellulose, a high number average molecular weight hydroxypropylmethylcellulose, and a beneficial drug.... | 10/03/1989 |
| 4871544 | Ruminant dispensing device A dispensing device is disclosed for delivering a beneficial agent. The device comprises (1) a housing defining an internal space, (2) an expandable composition comprising a dense member in the space, (3) a composition comprising a beneficial agent and a ... | 10/03/1989 |
| 4871360 | System for intravenous delivery of a beneficial drug at a regulated rates A formulation chamber is disclosed comprising a wall surrounding a space containing a beneficial agent. The formulation chamber has an inlet for admitting a fluid into the chamber and an outlet for letting the fluid containing the agent leave the chamber.... | 10/03/1989 |
| 4867969 | Hydrogel formulation for administering non-steroidal drugs A composition of matter comprising a drug, a neutral hydrogel and an ionic hydrogel. The composition can be administered from a delivery system to a biological receptor over time.... | 09/19/1989 |
| 4867982 | Transdermal drug delivery device A medical device for the transdermal delivery of an active agent through sensitive intact skin is provided. The device comprises a matrix containing the drug having reinforcing means, preferably in the form of a fabric, embedded in the upper surface of th... | 09/19/1989 |
| 4865598 | Dispensing system for administering beneficial agent A dispensing device is disclosed for delivering a beneficial agent. The device comprises (1) a housing defining an internal space, (2) an expandable composition in the space, (3) an aqueous sensitive beneficial agent formulation in the space, and (4) at l... | 09/12/1989 |
| 4865848 | Skin permeation enhancer compositions using sucrose esters A method for enhancing the transdermal flux of a transdermally deliverable drug through intact skin is described in which the drug is delivered simultaneously with sucrose monolaurate or a mixture of sucrose esters of coconut fatty acids, which is predomi... | 09/12/1989 |
| 4865585 | Method of administering drug by using cell comprising drug A formulation chamber is disclosed comprising a wall surrounding a lumen containing a device for delivering a beneficial agent. The chamber has an inlet for admitting a fluid into the chamber and an outlet for letting an agent formulation leave the chambe... | 09/12/1989 |
| 4863738 | Skin permeation enhancer compositions using glycerol monooleate A method for enhancing the flux of transdermally deliverable drugs through intact skin is described in which the drug is delivered simultaneously with glycerol monooleate. Preferred embodiments of therapeutic systems for delivering drug and glycerol monoo... | 09/05/1989 |
| 4863456 | Dosage form with improved delivery capability A dosage form is disclosed comprising a wall surrounding a compartment housing a first layer comprising a drug formulation, a middle layer comprising a hydrophobic composition, and a third layer comprising a hydrophilic composition.... | 09/05/1989 |
| 4863744 | Intestine drug delivery A delivery system is disclosed for delivering an agent to a selected environment of use having a pH of greater than 3.5.... | 09/05/1989 |
| 4859470 | Dosage form for delivering diltiazem A device is disclosed for delivering diltiazem at a controlled and substantially zero order rate over a prolonged period of time.... | 08/22/1989 |
| 4857052 | Intravenous system for delivering a beneficial agent A formulation chamber is disclosed comprising a wall surrounding a lumen containing a device for delivering a beneficial agent. The chamber has an inlet for admitting a fluid into the chamber and an outlet for letting an agent formulation leave the chambe... | 08/15/1989 |
| 4855141 | Device comprising means for protecting and dispensing fluid sensitive medicament A delivery device is disclosed for delivering a beneficial agent to an animal. The device comprises a wall housing an internal space, a beneficial agent in the space, expandable means in the space for causing the beneficial agent to be delivered from the ... | 08/08/1989 |
| 4853229 | Method for adminstering tiny pills A delivery system is disclosed for delivering a beneficial agent to an environment of use. The delivery system comprises a plurality of tiny dosage forms comprising a beneficial agent. The delivery system also comprises means for maintaining (a) the physi... | 08/01/1989 |
| 4851229 | Composition comprising a therapeutic agent and a modulating agent An osmotic delivery system is disclosed for delivering a useful agent at a controlled and constant rate modulated by a pulsed delivery of the useful agent to an environment of use.... | 07/25/1989 |
| 4851231 | System for delivering drug in selected environment of use A delivery system is disclosed for delivering an agent to a selected environment of use having a pH of greater than 3.5.... | 07/25/1989 |
| 4851232 | Drug delivery system with means for obtaining desirable in vivo release rate pattern A delivery device is disclosed for delivering a beneficial drug to a biological environment of use. The device comprises a hydrogel reservoir containing tiny pills. The tiny pills comprise a wall surrounding a drug core.... | 07/25/1989 |
| 4849226 | Method for increasing oxygen supply by administering vasodilator A medical bandage is disclosed comprising a reservoir containing a gelled fluid, rheological agent and a drug. A method of using the bandage for producing a beneficial effect is disclosed also.... | 07/18/1989 |
| 4846826 | Method for treating ischemic conditions A method is disclosed for treating an ischemic condition. The method comprises coadministering topically and internally a vasodilator to a patient having the condition for treating the condition.... | 07/11/1989 |
| 4847093 | Dosage form with means for governing rate of gas formation An osmotic device is disclosed comprising a release rate controlling wall that surrounds a carbon dioxide generating compound.... | 07/11/1989 |
| 4844984 | Dispensing system with means for increasing delivery of beneficial agent from the system A dispensing system is disclosed comprising a wall surrounding a lumen. The lumen comprises (1) a thermo responsive composition comprising a beneficial agent, (2) means for occupying space in the lumen for pushing the thermo responsive composition from th... | 07/04/1989 |
| 4842867 | Pulsed drug delivery of doxylamine A dosage form comprising (1) an immediately available dose of a beneficial drug followed by a timed delayed dose of drug, or (2) a timed delayed dose of drug.... | 06/27/1989 |
| 4837111 | Dosage form for dispensing drug for human therapy An osmotic dosage system is disclosed for delivering the therapeutically beneficial drug doxazosin to an environment of use over time.... | 06/06/1989 |
| 4837027 | Transdermal drug delivery device A diffusional drug delivery device is described which can provide for stability of the adhesive and system components, elimination of the initial burst of drug and hence irritation, and to provide for delayed onset of therapeutic effect along with deliver... | 06/06/1989 |
| 4834979 | Medical bandage for administering beneficial drug A medical bandage is disclosed comprising a reservoir containing a gelled fluid, rheological agent and a drug. A method of using the bandage for producing a beneficial effect is disclosed also.... | 05/30/1989 |
| 4832953 | Method for preventing the formation of a crystalline hydrate in a dispersion of a liquid in a monaqueous matrix A method for preventing the formation of crystalline hydrates in a dispersion of a hydratable liquid in a nonaqueous matrix is disclosed. The method is particularly useful in the manufacture of laminated items formed from such dispersions and comprises fo... | 05/23/1989 |
| 4824675 | Dispenser with movable matrix comprising a plurality of tiny pills A dispenser is disclosed for delivering tiny pills to an environment of use. The dispenser comprising a wall that surrounds an internal space comprising a first mean in the dispenser for changing from a dispenser state to an environment of use state on le... | 04/25/1989 |
| 4816263 | Dosage form for treating cardiovascular diseases comprising isradipine An osmotic device is disclosed comprising a first composition, and a second composition with the beneficial drug isradipine in the first composition.... | 03/28/1989 |
| 4814181 | Dosage form comprising fast agent delivery followed by slow agent delivery A dosage form is disclosed comprising a wall that surrounds a compartment with an exit means in the wall. The compartment comprises a first or fast releasing lamina and a second or short releasing lamina that are delivered through the exit means over two ... | 03/21/1989 |
| 4814180 | Agent dispenser comprising a semipermeable wall surrounding single-piece or two-piece container A dispenser is disclosed for delivering a beneficial agent to an environment of use. The dispenser comprises a semipermeable wall surrounding a compartment containing a heat responsive composition, and an expandable composition. A passageway in the wall c... | 03/21/1989 |
| 4812313 | Method for lessening the incidence of anginal attacks A medical bandage is disclosed comprising a reservoir containing a gelled fluid, rheological agent and a drug. A method of using the bandage for producing a beneficial effect is disclosed also.... | 03/14/1989 |
| 4810502 | Pseudoephedrine brompheniramine therapy A dosage form is disclosed for delivering the beneficial drugs pseudoephedrine and brompheniramine to a biological environment of use.... | 03/07/1989 |
| 4801461 | Pseudoephedrine dosage form A dosage form is disclosed for delivering the beneficial drug pseudoephedrine to a biological environment of use.... | 01/31/1989 |
| 4800056 | Process for making dispenser with cooperating elements A method of forming a dispenser for delivering a beneficial agent to a biological environment. A beneficial agent and an expandable composition are placed in a capsule made of fluid dissolvable material. The capsule is closed and surrounded by a semiperme... | 01/24/1989 |
| 4790820 | Parenteral agent dispensing equipment with drug releasing member A parenteral delivery system and a formulation chamber are disclosed for administering a beneficial agent. The parenteral delivery system comprises a drip chamber and a formulation chamber. The formulation chamber comprises a wall surrounding an internal ... | 12/13/1988 |
| 4786503 | Dosage form comprising parallel lamine A bilaminated dosage form is disclosed comprising at least 30 weight percent cellulose ether, a first lamina and a second lamina with each lamina comprising a different cellulose ether formulation, and a drug in at least one of the lamina.... | 11/22/1988 |
| 4786500 | Programmable agent delivery system This invention pertains to a programmable delivery system.... | 11/22/1988 |
| 4783337 | Osmotic system comprising plurality of members for dispensing drug An osmotic system is disclosed comprising a wall comprising in at least a part of a semipermeable material that surrounds a compartment. The compartment contains a first osmotic composition comprising a beneficial drug selected from the group consisting o... | 11/08/1988 |
| 4781714 | Dispenser for delivering thermo-responsive composition A dispenser is disclosed for delivering a beneficial agent formulation to a warm, fluid environment of use. The dispenser comprises an outer semipermeable wall surrounding and laminating an inner hydrophilic, swellable wall. The walls define an interior s... | 11/01/1988 |
