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| Number | Title | Issue Date |
| 8440410 | Reagents and methods for use in cancer diagnosis, classification and therapy Methods and reagents for classifying tumors and for identifying new tumor classes and subclasses. Methods for correlating tumor class or subclass with therapeutic regimen or outcome, for identifying appropriate (new or known) therapies for particular classes or subc... | 05/14/2013 |
| 8425474 | Method and apparatus for dispensing a composition A pharmaceutical dispenser including a tube having an open end and a space filled with a composition, and an applicator including a first end removably coupled to the open end of the tube and a longitudinal portion with at least one aperture is described. The dispen... | 04/23/2013 |
| 8399622 | Reagents and methods for use in cancer diagnosis, classification and therapy Methods and reagents for classifying tumors and for identifying new tumor classes and subclasses. Methods for correlating tumor class or subclass with therapeutic regimen or outcome, for identifying appropriate (new or known) therapies for particular classes or subc... | 03/19/2013 |
| 8389793 | Methods for increasing the diversity of monoclonal antibodies produced against an antigen The present invention relates to methods for increasing the diversity of monoclonal antibodies produced against an antigen. The methods of the invention utilize immunization of a murine host defective in one or more enzymes involved in a post-translational modificat... | 03/05/2013 |
| 8378064 | Hydrophilic polymers as medical lubricants and gels The present invention provides new biopolymers which mimic the properties of natural polysaccharides found in vivo. The inventive polysaccharides can be used as viscosupplements, viscoelastics, tissue space fillers, and/or anti-adhesive agents. Also provided are pha... | 02/19/2013 |
| 8377419 | Hyperpolarized solid materials with long spin relaxation times for use as imaging agents in magnetic resonance imaging An imaging agent is disclosed for use in nuclear magnetic resonance imaging. The imaging agent includes a first substance and a second substance. The first substance includes at least one atom having non-zero nuclear spin providing a polarized magnetic orientation. ... | 02/19/2013 |
| 8373615 | Method and system for splitting a display zone of a screen, and computer program product A system for splitting a display zone of a screen is installed in an electronic device having a screen, and includes a detecting module for detecting screen pixels. A splitting processor receives a splitting instruction containing a splitting number n, and splits th... | 02/12/2013 |
| D675257 | Display sleeve | 01/29/2013 |
| 8358463 | Micro particle image velocimetry, and particle image-capturing method thereof A particle image-capturing method includes controlling a light-emitting diode unit to emit light so as to illuminate a fluid through an annular condenser, particles in which scattering the light, and controlling an image-capturing unit to capture images of the scatt... | 01/22/2013 |
| 8357400 | Stimuli-responsive systems for controlled drug delivery A method of delivering a therapeutic agent by providing a cross-linked polymer encapsulating the therapeutic agent to a site in a patient. The degradation rate of the cross-linked polymer is correlated with a local concentration of an indicator, and the therapeutic ... | 01/22/2013 |
| 8343751 | Use of live bacteria for growth promotion in animals The present invention relates to the use of F4+ non-pathogenic Escherichia coli strains to promote growth in an animal. The present invention also relates to the use of such strains to homogenize growth among a herd of animals. More specifically, t... | 01/01/2013 |
| 8283036 | Composite nanoparticles containing organic ions A composite nanoparticle comprising a nanoparticle confined within a cross-linked collapsed polyelectrolyte polymer wherein the nanoparticle comprises a charged organic ion. ... | 10/09/2012 |
| 8280236 | Electric tankless water heater In various embodiments, the invention provides a system for heating a liquid, such as, for example, water, comprising a plurality of liquid heaters, the inlets and outlets of which are respectively connected in a parallel flow relationship by respective manifolds, a... | 10/02/2012 |
| 8257785 | Producing composite nanoparticles A method for producing a composite nanoparticle, including the steps of: changing the conformation of a dissolved polyelectrolyte polymer from a first extended conformation to a more compact conformation by changing a solution condition so that at least a portion of... | 09/04/2012 |
| 8252891 | Purification of polycarbonates The present disclosure provides, in part, a method for removing a catalyst from a product of catalyzed aliphatic polycarbonate polymerization reaction. ... | 08/28/2012 |
| 8247520 | Polycarbonate polyol compositions and methods In one aspect, the present disclosure encompasses polymerization systems for the copolymerization of CO2 and epoxides comprising 1) a catalyst including a metal coordination compound having a permanent ligand set and at least one ligand that is a polymeri... | 08/21/2012 |
| 8235974 | Method for hair removal A method for hair removal from a skin area by selective photo-inactivation of the pilo-sebaceous apparatus using derivatives of ALA with alkylene-glycol chains. Selectivity of the method is further enhanced by treatment of the epidermis by agents reducing PpIX level... | 08/07/2012 |
| 8211575 | Batteries containing bismuth glass compositions Disclosed are glass compositions, glass fiber compositions, glass fiber battery separators, glass fiber filter media, battery additives and active materials formed with glass compositions disclosed, glass fiber radiation shields, and glass fiber paper compositions. ... | 07/03/2012 |
| 8197733 | Wood grain extrusions The invention is the provision of an elongated imitation wood product or component which has a plastic core and a plastic coating on at least one surface with the coating, which is of two different colours and which has a randomly swirled pattern, giving a realistic... | 06/12/2012 |
| 8182867 | Producing composite nanoparticles containing organic ions A method for producing a composite nanoparticle, including the steps of, collapsing at least a portion of a polyelectrolyte polymer in solution about one or more precursor moieties to form a composite precursor moiety having a mean diameter in the range between abou... | 05/22/2012 |
| 8158138 | Urea compositions and their methods of manufacture Urea compositions useful for treatment of dermatological conditions. The compositions, which are free from perceptible solids, may include at least about 50 wt-% urea, zinc pyrithione, and lactic acid, and may be formulated as a topical gel. ... | 04/17/2012 |
| 8137509 | Asymmetric synthesis of rocaglamides via enantioselective photocycloaddition mediated by chiral brønsted acids The present invention provides a new strategies for the synthesis of compounds of the rocaglamide family and related natural products. The synthetic approach generally involves photochemical generation of an oxidopyrylium species from a 3-hydroxychromone derivative ... | 03/20/2012 |
| 8104434 | Electric tankless water heater In various aspects, the present invention provides an electric tankless liquid heater system capable of delivering liquid, such as, for example, water, with an acceptable increase in output liquid temperature upon a sudden and substantial decrease in liquid demand. ... | 01/31/2012 |
| 8093417 | Lipoxin analogs and methods for the treatment of periodontal disease This invention provides new lipoxin analogs, compositions containing analogs, and methods of using these compounds and compositions for treating and preventing oral inflammation, including gingivitis, periodontitis, and other forms of periodontal disease. The invent... | 01/10/2012 |
| 8093351 | Copolymerization of propylene oxide and carbon dioxide and homopolymerization of propylene oxide Copolymers of propylene oxide and carbon dioxide and homopolymers of propylene oxide are made using two dimensional double metal cyanide complexes having the formula Co[M(CN)4] or hydrated or partially dehydrated form thereof. There is no propylene carbon... | 01/10/2012 |
| 8084397 | Methods to produce polymer nanoparticles and formulations of active ingredients The present invention provides a composition including a polymer nanoparticle and at least one agricultural active compound incorporated with the nanoparticle, wherein the nanoparticle are less than 100 nm in diameter, and the polymer includes a polyelectrolyte.... | 12/27/2011 |
| 8062668 | Stimuli-responsive systems for controlled drug delivery A method of delivering a therapeutic agent by providing a cross-linked polymer encapsulating the therapeutic agent to a site in a patient. The degradation rate of the cross-linked polymer is correlated with a local concentration of an indicator, and the therapeutic ... | 11/22/2011 |
| 8029797 | Multivalent HIV immunogenic compositions comprising a pool of lipidated and nonlipidated peptides representing Gag and Env variable regions An anti-HIV vaccine composition is disclosed. The vaccine comprises an combination of immunogenic peptide mixtures, which mixtures may be prepared in a single synthesis. The composition collectively represents the in vivo variability seen in immunogenic epitopes fro... | 10/04/2011 |
| 8026317 | Isotactic specific catalyst for direct production of highly isotactic poly (propylene oxide) or highly isotactic poly (butylene oxide) (Salph or methoxy salph) Co (initiating ligand) catalyze homopolymerizing rac-PO to produce pure highly isotactic PPO and rac-1-butylene oxide to produce pure isotactic poly(butylene oxide). A product is unfractionated isotactic PPO of m-dyad content >81%, normally ... | 09/27/2011 |
| 7988763 | Use of a binary salt flux of NaCl and MgClfor the purification of aluminium or aluminium alloys, and method thereof A method for the purification of a metal selected from the group consisting of aluminum and aluminum alloys, wherein the metal is in a liquid phase and is contacted with a salt flux consisting of a binary mixture of NaCl and MgCl2. Preferably, more than 2... | 08/02/2011 |
| 7981411 | Use of live bacteria for growth promotion in animals The present invention relates to the use of F4+ non-pathogenic Escherichia coli strains to promote growth in an animal. The present invention also relates to the use of such strains to homogenize growth among a herd of animals. More specifically, t... | 07/19/2011 |
| 7927608 | polypeptides and polynucleotides encoding same and their use in vaccinal and diagnostic applications The present invention relates to the field of Streptococcus. More specifically, the present invention relates to the identification of polypeptides and polynucleotide sequences encoding the same which are involved in the pathogenic mechanism of S. suis... | 04/19/2011 |
| 7910335 | Methods and compositions for labeling nucleic acids The present invention relates to methods for the labeling of nucleic acid polymers in vitro and in vivo. In particular, the methods include a [3+2] cycloaddition between a nucleotide analogue incorporated into a nucleic acid polymer and a reagent attached to a label... | 03/22/2011 |
| 7879861 | Combi-molecules having EGFR and DNA targeting properties A series of new chemical agents that demonstrate anti-tumor activity are described. The new chemical agents combine two major mechanisms of anti-tumor action. In an embodiment, the agents are capable of both inhibiting EGFR and damaging DNA while also, upon degradat... | 02/01/2011 |
| 7875734 | Low pressure carbonylation of heterocycles Heterocycles, e.g., epoxides, are carbonylated at low pressure with high percentage conversion to cyclic, ring expanded products using the catalyst where L is tetrahydrofuran (THF). ... | 01/25/2011 |
| 7858617 | 2-oxy-benzoxazinone derivatives for the treatment of obesity The use of a compound comprising formula (I): or a salt, ester, amide or prodrug thereof in the inhibition of an enzyme whose preferred mode of action is to catalyse the hydrolysis of an ester functionality, e.g. in the con... | 12/28/2010 |
| 7825113 | 2-oxy-benzoxazinone derivatives for the treatment of obesity The use of a compound comprising formula (I): or a salt, ester, amide or prodrug thereof in the inhibition of an enzyme whose preferred mode of action is to catalyse the hydrolysis of an ester functionality, e.g. in the con... | 11/02/2010 |
| 7816544 | Synthesis of rocaglamide natural products via photochemical generation of oxidopyrylium species The present invention provides new strategies for the synthesis of compounds of the rocaglamide family and related natural products. In particular, the new biomimetic synthetic approach involves photochemical generation of an oxidopyrylium species from a 3-hydroxych... | 10/19/2010 |
| 7816518 | Porphyrin derivatives and their use in photon activation therapy The present invention relates to the use of a compound of formula (I) in the manufacture of a pharmaceuticals composition for cell death by photo activation therapy and the use of the compounds in the prevention and/or treatment of cancer. | 10/19/2010 |
| 7816084 | TLE3 as a marker for chemotherapy Methods of using TLE3 as a marker for predicting the likelihood that a patient's cancer will respond to chemotherapy. Methods of using TLE3 as a marker for selecting a chemotherapy for a cancer. ... | 10/19/2010 |
