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| Number | Title | Issue Date |
| 8182867 | Producing composite nanoparticles containing organic ions A method for producing a composite nanoparticle, including the steps of, collapsing at least a portion of a polyelectrolyte polymer in solution about one or more precursor moieties to form a composite precursor moiety having a mean diameter in the range between abou... | 05/22/2012 |
| 8158138 | Urea compositions and their methods of manufacture Urea compositions useful for treatment of dermatological conditions. The compositions, which are free from perceptible solids, may include at least about 50 wt-% urea, zinc pyrithione, and lactic acid, and may be formulated as a topical gel. ... | 04/17/2012 |
| 8137509 | Asymmetric synthesis of rocaglamides via enantioselective photocycloaddition mediated by chiral brønsted acids The present invention provides a new strategies for the synthesis of compounds of the rocaglamide family and related natural products. The synthetic approach generally involves photochemical generation of an oxidopyrylium species from a 3-hydroxychromone derivative ... | 03/20/2012 |
| 8104434 | Electric tankless water heater In various aspects, the present invention provides an electric tankless liquid heater system capable of delivering liquid, such as, for example, water, with an acceptable increase in output liquid temperature upon a sudden and substantial decrease in liquid demand. ... | 01/31/2012 |
| 8093417 | Lipoxin analogs and methods for the treatment of periodontal disease This invention provides new lipoxin analogs, compositions containing analogs, and methods of using these compounds and compositions for treating and preventing oral inflammation, including gingivitis, periodontitis, and other forms of periodontal disease. The invent... | 01/10/2012 |
| 8093351 | Copolymerization of propylene oxide and carbon dioxide and homopolymerization of propylene oxide Copolymers of propylene oxide and carbon dioxide and homopolymers of propylene oxide are made using two dimensional double metal cyanide complexes having the formula Co[M(CN)4] or hydrated or partially dehydrated form thereof. There is no propylene carbon... | 01/10/2012 |
| 8084397 | Methods to produce polymer nanoparticles and formulations of active ingredients The present invention provides a composition including a polymer nanoparticle and at least one agricultural active compound incorporated with the nanoparticle, wherein the nanoparticle are less than 100 nm in diameter, and the polymer includes a polyelectrolyte.... | 12/27/2011 |
| 8062668 | Stimuli-responsive systems for controlled drug delivery A method of delivering a therapeutic agent by providing a cross-linked polymer encapsulating the therapeutic agent to a site in a patient. The degradation rate of the cross-linked polymer is correlated with a local concentration of an indicator, and the therapeutic ... | 11/22/2011 |
| 8029797 | Multivalent HIV immunogenic compositions comprising a pool of lipidated and nonlipidated peptides representing Gag and Env variable regions An anti-HIV vaccine composition is disclosed. The vaccine comprises an combination of immunogenic peptide mixtures, which mixtures may be prepared in a single synthesis. The composition collectively represents the in vivo variability seen in immunogenic epitopes fro... | 10/04/2011 |
| 8026317 | Isotactic specific catalyst for direct production of highly isotactic poly (propylene oxide) or highly isotactic poly (butylene oxide) (Salph or methoxy salph) Co (initiating ligand) catalyze homopolymerizing rac-PO to produce pure highly isotactic PPO and rac-1-butylene oxide to produce pure isotactic poly(butylene oxide). A product is unfractionated isotactic PPO of m-dyad content >81%, normally ... | 09/27/2011 |
| 7988763 | Use of a binary salt flux of NaCl and MgClfor the purification of aluminium or aluminium alloys, and method thereof A method for the purification of a metal selected from the group consisting of aluminum and aluminum alloys, wherein the metal is in a liquid phase and is contacted with a salt flux consisting of a binary mixture of NaCl and MgCl2. Preferably, more than 2... | 08/02/2011 |
| 7981411 | Use of live bacteria for growth promotion in animals The present invention relates to the use of F4+ non-pathogenic Escherichia coli strains to promote growth in an animal. The present invention also relates to the use of such strains to homogenize growth among a herd of animals. More specifically, t... | 07/19/2011 |
| 7927608 | polypeptides and polynucleotides encoding same and their use in vaccinal and diagnostic applications The present invention relates to the field of Streptococcus. More specifically, the present invention relates to the identification of polypeptides and polynucleotide sequences encoding the same which are involved in the pathogenic mechanism of S. suis... | 04/19/2011 |
| 7910335 | Methods and compositions for labeling nucleic acids The present invention relates to methods for the labeling of nucleic acid polymers in vitro and in vivo. In particular, the methods include a [3+2] cycloaddition between a nucleotide analogue incorporated into a nucleic acid polymer and a reagent attached to a label... | 03/22/2011 |
| 7879861 | Combi-molecules having EGFR and DNA targeting properties A series of new chemical agents that demonstrate anti-tumor activity are described. The new chemical agents combine two major mechanisms of anti-tumor action. In an embodiment, the agents are capable of both inhibiting EGFR and damaging DNA while also, upon degradat... | 02/01/2011 |
| 7875734 | Low pressure carbonylation of heterocycles Heterocycles, e.g., epoxides, are carbonylated at low pressure with high percentage conversion to cyclic, ring expanded products using the catalyst where L is tetrahydrofuran (THF). ... | 01/25/2011 |
| 7858617 | 2-oxy-benzoxazinone derivatives for the treatment of obesity The use of a compound comprising formula (I): or a salt, ester, amide or prodrug thereof in the inhibition of an enzyme whose preferred mode of action is to catalyse the hydrolysis of an ester functionality, e.g. in the con... | 12/28/2010 |
| 7825113 | 2-oxy-benzoxazinone derivatives for the treatment of obesity The use of a compound comprising formula (I): or a salt, ester, amide or prodrug thereof in the inhibition of an enzyme whose preferred mode of action is to catalyse the hydrolysis of an ester functionality, e.g. in the con... | 11/02/2010 |
| 7816544 | Synthesis of rocaglamide natural products via photochemical generation of oxidopyrylium species The present invention provides new strategies for the synthesis of compounds of the rocaglamide family and related natural products. In particular, the new biomimetic synthetic approach involves photochemical generation of an oxidopyrylium species from a 3-hydroxych... | 10/19/2010 |
| 7816518 | Porphyrin derivatives and their use in photon activation therapy The present invention relates to the use of a compound of formula (I) in the manufacture of a pharmaceuticals composition for cell death by photo activation therapy and the use of the compounds in the prevention and/or treatment of cancer. | 10/19/2010 |
| 7816084 | TLE3 as a marker for chemotherapy Methods of using TLE3 as a marker for predicting the likelihood that a patient's cancer will respond to chemotherapy. Methods of using TLE3 as a marker for selecting a chemotherapy for a cancer. ... | 10/19/2010 |
| 7812054 | Lipoxin analogs and methods for the treatment of periodontal disease This invention provides new lipoxin analogs, compositions containing analogs, and methods of using these compounds and compositions for treating and preventing oral inflammation, including gingivitis, periodontitis, and other forms of periodontal disease. The invent... | 10/12/2010 |
| 7811774 | Reagents and methods for use in cancer diagnosis, classification and therapy Methods and reagents for classifying tumors and for identifying new tumor classes and subclasses. Methods for correlating tumor class or subclass with therapeutic regimen or outcome, for identifying appropriate (new or known) therapies for particular classes or subc... | 10/12/2010 |
| 7776853 | 2-amino-benzoxazinone derivatives for the treatment of obesity The use of a compound comprising formula (I): or a salt, ester, amide or prodrug thereof in the inhibition of an enzyme whose preferred mode of action is to catalyse the hydrolysis of an ester functionality, e.g. in the con... | 08/17/2010 |
| 7767421 | Methods and compositions for labeling nucleic acids The present invention relates to methods for the labeling of nucleic acid polymers in vitro and in vivo. Certain methods are provided that include a [3+2] cycloaddition between a nucleotide analogue incorporated into a nucleic acid polymer and a reagent attached to ... | 08/03/2010 |
| 7763446 | Chimeric DNA-binding proteins Chimeric proteins containing composite DNA-binding regions are disclosed together with DNA constructs encoding them, compositions containing them and applications in which they are useful. ... | 07/27/2010 |
| 7754431 | TLE3 as a marker for chemotherapy Methods of using TLE3 as a marker for predicting the likelihood that a patient's cancer will respond to chemotherapy. Methods of using TLE3 as a marker for selecting a chemotherapy for a cancer. ... | 07/13/2010 |
| 7751469 | Correlation shaping matched filter receiver The present invention is directed toward an apparatus and method for receiving signals, demodulating the signals and shaping the correlation of the output of a correlation demodulator. The present invention can be used irrespective of whether the received signals ha... | 07/06/2010 |
| 7723256 | Polycarbonates made using highly selective catalysts Poly(propylene carbonates) are prepared from propylene oxide and CO2 with less than 10% cyclic propylene carbonate by product using cobalt based catalysts of structure preferably in combination with salt cocataly... | 05/25/2010 |
| 7700650 | Lipoxin analogs and method for the treatment of periodontal disease This invention provides new lipoxin analogs, compositions containing these analogs, and methods of using these compounds and compositions for treating and preventing oral inflammation, including gingivitis, periodontitis, and other forms of periodontal disease. The ... | 04/20/2010 |
| 7674873 | Polycarbonates made using highly selective catalysts Poly(propylene carbonates) are prepared from propylene oxide and CO2 with less than 10% cyclic propylene carbonate by product using cobalt based catalysts of structure preferably in combination with salt cocataly... | 03/09/2010 |
| 7569709 | Low pressure carbonylation of heterocycles Heterocycles, e.g., epoxides, are carbonylated at low pressure with high percentage conversion to cyclic, ring expanded products using the catalyst where L is tetrahydrofuran (THF). ... | 08/04/2009 |
| 7563931 | Process for preparation of phenethylamine derivatives A process for the preparation of a compound of formula I, wherein R1 and R2 are ortho or para substituents, independently selected from the group consisting of hydrogen, hydroxyl, C1-C6... | 07/21/2009 |
| 7504225 | Reagents and methods for use in cancer diagnosis, classification and therapy Methods and reagents for classifying tumors and for identifying new tumor classes and subclasses. Methods for correlating tumor class or subclass with therapeutic regimen or outcome, for identifying appropriate (new or known) therapies for particular classes or subc... | 03/17/2009 |
| D587826 | Multiple light configuration for a vehicle | 03/03/2009 |
| 7485441 | Chimeric DNA-binding proteins Chimeric proteins containing composite DNA-binding regions are disclosed together with DNA constructs encoding them, compositions containing them and applications in which they are useful. ... | 02/03/2009 |
| 7470668 | Method of use of specific natriuretic peptide receptor c ligands, transgenic non-human mammals expressing specific natriuretic peptide receptor c antagonists and cells thereof A method of using an osteocrin (Ostn) or a NPR-C specific Ostn peptide derivative for increasing osteogenesis in a mammal comprising administering a therapeutically effective amount of said Ostn or NPR-C specific Ostn peptide derivative to the mammal. ... | 12/30/2008 |
| 7435854 | Methods for preparing O-desmethylvenlafaxine The present invention provides an efficient method of making O-desmethyl-venlafaxine. ... | 10/14/2008 |
| 7297545 | Clinical method for the genetic screening of newborns using tandem mass spectrometry and internal standards therefor A method for screening newborns using electrospray tandem mass spectrometry. The method improves the current protocols that use tandem mass spectrometry by assuring accurate and consistent results at the clinical level through enhanced quality controls and quality a... | 11/20/2007 |
| 7291347 | Succinate salt of O-desmethyl-venlafaxine A novel salt of O-desmethyl venlafaxine is provided, O-desmethylvenlafaxine succinate. Pharmaceutical compositions, dosage forms and methods of use are also provided. ... | 11/06/2007 |
