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Patent No. 6293874

User-operated amusement apparatus for kicking the user's buttocks

An apparatus including a user-operated and controlled apparatus for self-infliction of repetitive blows to the user's buttocks by a plurality of elongated arms bearing flexible extensions that rotate under the user's control.

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Attorney: Lauro, Esq.; Peter C.


Number of patents: 120
Last date: May 08, 2012

1      
NumberTitleIssue Date
8173361Method of determining metabolism of a test agent
A method for detecting one or more metabolites of a test agent in a tissue including: A) incubating a test agent and an enzyme within a three-dimensional structure comprising a first mold or polymer scaffold, a semi-permeable membrane, and a second mold or polymer s...
05/08/2012
8168220Dosage forms of active ingredients containing hydroxystilbene for treating menopausal complaints
The invention relates to novel dosage forms containing hydroxystilbene, to a method for producing said dosage forms and to their use for treating female menopausal complaints, juvenile oligomenorrhoea and dysmenorrhoea, primary and secondary amenorrhoea or endometri...
05/01/2012
8160751Devices, systems and methods for flow-compensating pump-injector synchronization
Systems, devices, and methods to mitigate the pressure disturbance associated with the injection of low-pressure analyte samples into a high-pressure HPLC fluid stream, to enhance chromatographic performance related to retention time and reproducibility. The preferr...
04/17/2012
8158443Turbidimetric immunoassay for assessing human Cystatin C
There is a demand for improved turbidimetric immunoassays for human Cystatin C in biological samples, especially in human clinical samples of body fluids. The present invention provides a turbidimetric immunoassay method and reagent set enabling measurement of human...
04/17/2012
8147562Three dimensional construct for the design and fabrication of physiological fluidic networks
The present invention relates to methods for the design and fabrication of biological constructs, such as organ simulants or organ replacements, which contain complex microfluidic architecture. Designs of the present invention provide increased space in the lateral ...
04/03/2012
8139211Fluorescence polarization imaging device and method
The present invention is directed to a novel multi-spectral exogenous fluorescence polarization imaging technique that enables rapid imaging of large tissue fields. The imaging device includes a tunable monochromatic light source and a CCD camera. Linear polarizers ...
03/20/2012
8138170Immunosuppressive Ningalin compounds
The present invention provides compositions and methods comprising ningalins for use in modulating immune responses to infection, injury, allergy and/or transplantation. ...
03/20/2012
8136748Grating plate for container/grater for friable food products
A grating plate (1) for a container/grater for friable food products, in particular hard cheese, is described, which is contained in a base (10) on which a reverse cup-shaped element is assembled for defining a chamber for the product, the grating plat...
03/20/2012
8133878Methods for treating restenosis
Restenosis in a subject can be treated by administering to a tissue, e.g., a blood vessel, of the subject an agent that increases SERCA activity. For example, a stent that is coated with the agent can be introduced into a blood vessel. ...
03/13/2012
8126240Vertebral fracture quantification
A method of deriving an estimate of the extent of fracture in a vertebra shown in an image of part of A spine is provided. The images of at least two vertebrae are segmented to obtain data representative of the shape and size of each of the vertebrae. An approximati...
02/28/2012
8123949Methods for separating compounds
Methods and systems for analyzing samples using multi-dimensional chromatography are disclosed. ...
02/28/2012
8114231Gassing of emulsion explosives with nitric oxide
A method for gassing an emulsion explosives to sensitize the explosive to detonation and/or for density modification is described. The method comprises reacting a compound having an enol group, or a deprotonated enolate form of the enol group, with a nitrosating age...
02/14/2012
8107067Opaque additive to block stray light in teflon AF light-guiding flowcells
The present invention is directed to the use of a light absorbing wall material to eliminate stray light paths in light-guiding structures, such as those used for HPLC absorbance detection. More specifically, the present invention relates to the use of carbon-doped ...
01/31/2012
8097456Nanotopographic compositions and methods for cellular organization in tissue engineered structures
The present invention relates to tissue engineered compositions and methods comprising nanotopographic surface topography (“nanotopography”) for use in modulating the organization and/or function of multiple cell types. ...
01/17/2012
8096216Chain-type flexible cutting edge
A chain-type flexible cutting edge, particularly for bush-cutter is described, comprising at least one linear connecting and cutting link (3) and at least one toothed connecting and cutting link (5) mutually connected in an articulated manner in order ...
01/17/2012
8092490Photochemical tissue bonding
Photochemical tissue bonding methods include the application of a photosensitizer to a tissue and/or tissue graft, followed by irradiation with electromagnetic energy to produce a tissue seal. The methods are useful for tissue adhesion, such as in wound closure, tis...
01/10/2012
8088622P27 and P21 in gene therapies
The expansion of a population of stem cells or progenitor cells, or precursors thereof, may be accomplished by disrupting or inhibiting p21cip1/waf1 and/or p27, cyclin dependent kinase inhibitors. In the absence of p27 activity, progenitor cells move into...
01/03/2012
8080889Aeolian system comprising power wing profiles and process for producing electric energy
An aeolian system is described for converting energy comprising at least one power wing profile (30) which can be driven from the ground immersed in at least one aeolian current (W) and a basic platform (1) for controlling the wing profile (30) ...
12/20/2011
8080431Nanoparticles
Materials and methods for studying and modulating the interaction of carbohydrate-containing moieties with other species are described, in particular, small particles, e.g. clusters of metal or semiconductor atoms, which can be employed as a substrate for immobilisi...
12/20/2011
8058061Vector encoding human globin gene and use thereof in treatment of hemoglobinopathies
Recombinant lentiviral vectors having a region encoding a functional β-globin gene; and large portions of the β-globin locus control regions which include DNase I hypersensitive sites HS2, HS3 and HS4 provides expression of β-globin when introduced into a mammal,...
11/15/2011
8045263Device and method for wide-field and high resolution imaging of tissue
A device for wide-field and high resolution imaging of an object surface includes first and second imaging modalities, a lens associated with the second imaging modality. The first imaging modality is high resolution with a first observation line. The second imaging...
10/25/2011
7989606Phosphatase inhibitor protein-1 as a regulator of cardiac function
The present invention relates to novel nucleic acids which encode novel mutant forms of Inhibitor Protein-1 (1-1). In particular, the 1-1 mutant forms comprise altered phosphorylation sites of PKC-α. In addition, the present invention relates to methods of regulati...
08/02/2011
7988966Method for the potentiation of opioid analgesics effects on pain
According to the invention there is provided use of an anti-TrkA antibody capable of inhibiting the binding between NGF and TrkA combined with at least one opioid analgesic for the preparation of a medicament for treating and/or preventing pain. ...
08/02/2011
7974147Method and apparatus for monitoring memory addresses
Disclosed herein is a method and apparatus for monitoring a memory address transmitted along an address path and converted into a row or column address of memory. The method includes: generating a path decision signal for deciding whether to connect the address path...
07/05/2011
7972770Methods of detection of cancer using peptide profiles
The disclosed methods address the identification and monitoring of cancer in a subject using serum peptide profiles. Such profiles allow the detection of the differential presence of certain serum peptide markers in comparison with controls. The profiles can be dete...
07/05/2011
7967016Apparatus and method for laser treatment with spectroscopic feedback
A platform Smart Scalpel system using rapid real-time feedback for effecting laser treatment. The platform system includes an imaging system for rapid real-time detection of tissue characteristics, a processing system for processing the detected characteristics, and...
06/28/2011
7960348Metastin derivatives and use thereof
The present invention provides stable metastin derivatives having excellent biological activities (a cancer metastasis suppressing activity, a cancer growth suppressing activity, a gonadotropic hormone secretion stimulating activity, sex hormone secretion stimulatin...
06/14/2011
7960166Microfabricated compositions and processes for engineering tissues containing multiple cell types
The present invention relates to a three-dimensional system, and compositions obtained therefrom, wherein individual layers of the system comprise channels divided longitudinally into two compartments by a centrally positioned membrane, and wherein each compartment ...
06/14/2011
7955846Compositions comprising female germline stem cells and methods of use thereof
The present invention relates to female germline stem cells and their progenitors, methods of isolation thereof, and methods of use thereof. ...
06/07/2011
7951364CaR receptor as a mediator of migratory cell chemotaxis and/or chemokinesis
This invention relates to methods and compositions for modulating movement of eukaryotic cells with migratory capacity. More specifically, the invention relates to methods and compositions for modulating movement of CaR receptor expressing cells of hematopoietic, ne...
05/31/2011
7951212Method and apparatus for producing synthesis gas from biomass
Method and apparatus for producing synthesis gas comprising the steps of combusting (4) a combustible gas to form hot flue gasses (7), passing the flue gasses (7) through heat storing means (1) so as to heat the heat storing means (1
05/31/2011
7943136Parathyroid hormone receptor activation and stem and progenitor cell expansion
The invention relates to methods for manipulating hematopoietic stem or progenitor cells, mesenchymal stem cells, epithelial stem cells, neural stem cells and related products through activation of the PTH/PTHrP receptor in neighboring cells. ...
05/17/2011
7932365Preparation and composition of inter-alpha inhibitor proteins from human plasma for therapeutic use
The invention relates to Inter-alpha inhibitor proteins (IαIp). The invention further relates to processes for purification of IαIp compositions and their use for treatment of human diseases such as sepsis and septic shock, rheumatoid arthritis, cancer and infecti...
04/26/2011
7921898Pneumatic automation system for mobile screens
A pneumatic automation system (1) is disclosed for mobile screens (2) comprising at least one of the mobile screens (2), a device for compressing a control fluid, a device for channeling and checking the control fluid, a device for pneumatically...
04/12/2011
7919177Porous inorganic/organic hybrid particles for chromatographic separations and process for their preparation
Novel material for chromatographic separations, processes for its preparation, and separations devices containing the chromatographic material. In particular, the disclosure describes porous inorganic/organic hybrid particles having a chromatographically-enhancing p...
04/05/2011
7917250Devices, systems and methods for flow-compensating pump-injector synchronization
Systems, devices, and methods to mitigate the pressure disturbance associated with the injection of low-pressure analyte samples into a high-pressure HPLC fluid stream to enhance chromatographic performance related to retention time and reproducibility. The injectio...
03/29/2011
7909994Mobile phase dilution scheme for enhanced chromatography
A method and device for increasing the loading capacity of a chromatography column through dilution of a mobile phase at the head of the column. A strong mobile phase is provided for dissolving a sample. A sample is injected into the strong mobile phase, and subsequ...
03/22/2011
7901676Therapeutic composition for the treatment of rheumatoid arthritis
A therapeutic composition and a method for rheumatoid arthritis is described. The composition comprises purified beta-glucuronidase at a concentration of between 200 and 10,000 Fishman units/ml and purified collagen at a concentration of between 0.5 and 2.5 mg/ml. T...
03/08/2011
7887754Polymeric solid supports for chromatography nanocolumns
Nanocolumn chromatography devices useful, e.g., in CEC and nanoLC are disclosed. An exemplary chromatography device of the invention includes a nanocolumn, e.g., a capillary, packed with a particulate stationary phase material and a solid support. The solid support,...
02/15/2011
7875175Mobile phase dilution scheme for enhanced chromatography
A method and device for increasing the loading capacity of a chromatography column through dilution of a mobile phase at the head of the column. A strong mobile phase is provided for dissolving a sample. A sample is injected into the strong mobile phase, and subsequ...
01/25/2011
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