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| Number | Title | Issue Date |
| 5198229 | Self-retaining gastrointestinal delivery device The present invention is directed to a fluid-imbibing drug delivery device having a first, low density such that it floats in the stomach contents for a predetermined prolonged period of time, during which prolonged period of time it dispenses a drug or o... | 03/30/1993 |
| 5198223 | Transdermal formulations, methods and devices The present invention provides compositions and methods for the transdermal administration of a therapeutically effective amount of a synthetic 19-nor-progesterone (ST-1435) and an estrogen, in combination, together with, optionally, a suitable permeation... | 03/30/1993 |
| 5180591 | Delivery device with a protective sleeve This invention relates to an active agent delivery device. More particularly, the invention relates to a delivery device that includes a sleeve to protect the delivery device from transient mechanical forces. The delivery device of the invention is robust... | 01/19/1993 |
| 5160741 | Reduction or prevention of skin irritation by drugs The present invention provides a method of reducing or preventing skin irritation of a weak base drug by inhibiting the accumulation of the drug in the lysosomes. The drug is irritating to humans, i.e., the drug is susceptible to inducing skin or mucosa i... | 11/03/1992 |
| 5149539 | Reduction or prevention of sensitization to drugs The present invention is directed to a method of reducing or preventing skin sensitization by inhibiting the immunological processing of a sensitizing drug as an antigen. The drug is sensitizing to humans, i.e., the drug is susceptible to inducing skin or... | 09/22/1992 |
| 5141750 | Delayed onset transdermal delivery device A diffusional drug delivery device is described which can provide for delayed onset of therapeutic effect and for delivery of the therapeutic agent in predetermined temporal patterns at optimum rates. Delay means are provided between the agent reservoir a... | 08/25/1992 |
| 5137727 | Delivery device providing beneficial agent stability The present invention is directed to an improved fluid-imbibing dispensing device for delivering a beneficial agent to a biological environment of use, the dispensing device being of the type having a housing which includes a fluid-impermeable first wall ... | 08/11/1992 |
| 5130139 | Reduction or prevention of skin irritation by drugs The present invention provides a method of reducing or preventing skin irritation of a weak base drug by inhibiting the accumulation of the drug in the lysosomes. The drug is irritating to humans, i.e., the drug is susceptible to inducing skin or mucosa i... | 07/14/1992 |
| 5122382 | Transdermal contraceptive formulations, methods and devices The present invention provides compositions and methods for the transdermal administration of a contraceptively effective amount of a synthetic 19-nor-progesterone (ST-1435) and an estrogen, in combination, together with a suitable permeation enhancer.... | 06/16/1992 |
| 5122128 | Orifice insert for a ruminal bolus There is disclosed an insert for the orifice of a ruminal bolus. The insert fits within the exit orifice of the ruminal bolus such that the medicated paste being discharged passes through the insert creating a back pressure within the paste compartment of... | 06/16/1992 |
| 5120545 | Reduction or prevention of sensitization to drugs The present invention is directed to a method of reducing or preventing skin sensitization by inhibiting the immunological processing of a sensitizing drug as an antigen. The drug is sensitizing to humans, i.e., the drug is susceptible to inducing skin or... | 06/09/1992 |
| 5110597 | Multi-unit delivery system A dispenser for use in a fluid environment which is capable of delivery of a plurality of discrete drug-containing units in any desired delivery pattern or profile.... | 05/05/1992 |
| 5071656 | Delayed onset transdermal delivery device A diffusional drug delivery device is described which can provide for delayed onset of therapeutic effect and for delivery of the therapeutic agent in predetermined temporal patterns at optimum rates. Delay means are provided between the agent reservoir a... | 12/10/1991 |
| 5024663 | Self-contained suction pump The present invention is directed to a self-contained suction pump for drawing a fluid, such as a sample of biological fluid from an animal body, and to a method for obtaining a fluid sample. The present invention is particularly useful for repetitive or ... | 06/18/1991 |
| 5023088 | Multi-unit delivery system A dispenser for use in a fluid environment which is capable of delivery of a plurality of discrete drug-containing units in any desired delivery pattern or profile.... | 06/11/1991 |
