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| Number | Title | Issue Date |
| 6534521 | 2-phenyl benzimidazole derivatives as MCP-1 antagonists The present invention relates to novel compounds and medical methods of treatment of inflammation, atherosclerosis, restenosis, and immune disorders especially those associated with lymphocyte or monocyte accumulation such as arthritis and transplant reje... | 03/18/2003 |
| 6506751 | Thiazolidinone compounds useful as chemokine inhibitors Disclosed are compounds of the Formula I ##STR1## wherein: Z is C or nothing, provided that when Z is nothing, R3 and R4 are nothing; A is S, S.dbd.O or O.dbd.S.dbd.O; R1 and R2 are independently hydrogen, lower alky... | 01/14/2003 |
| 6469048 | -pyrones for treating -pyrone responsive states Novel -pyrones are described. The -pyrones are useful in a method for controlling -pyrone responsive states in a mammal. The method includes administering to a mammal a therapeutically effective amount of an -pyrone such that c... | 10/22/2002 |
| 6348487 | 2-phenyl benzimidazole derivatives as MCP-1 antagonists Benzimidazole derivatives of Formula I or a pharmaceutically acceptable salt thereof are MCP-1 antagonists and are thus useful in the treatment of inflammation, atherosclerosis, restenosis, and immune disorders ##STR1## wherein A is N or CH; where W, X, Y... | 02/19/2002 |
| 6329356 | Phosphono-carboxylate compounds for treating amyloidosis Therapeutic compounds and methods for modulating amyloid deposition in a subject, whatever its clinical setting, are described. Amyloid deposition is modulated by the administration to a subject of an effective amount of a therapeutic compound comprising ... | 12/11/2001 |
| 6271256 | Methods for controlling gram negative bacteria in mammals with bicyclo spiroether compounds Methods for controlling growth of gram negative bacteria, such as Helicobacter pylori, which are agents associated with disorders of the gastrointestinal tract of a mammal are described. They include administering a therapeutically effective amount of a p... | 08/07/2001 |
| 6261553 | Mycoinsecticides against an insect of the grasshopper family An entomopathogenic fungus virulent against insects of the grasshopper family is described. The entomopathogenic fungus is a strain Beauveria bassiana. Also, formulations that include the entomopathogenic fungus are described. These formulations can be de... | 07/17/2001 |
| 6252136 | Transgenic organisms having tetracycline-regulated transcriptional regulatory systems Transgenic animals carrying two transgenes, the first coding for a transactivator fusion protein comprising a tet repressor and a polypeptide which directly or indirectly activates in eucaryotic cells, and the second comprising a gene operably linked to a... | 06/26/2001 |
| 6187550 | Methods and cell lines for screening compositions and genes for ability to interact with IL-1ଲ and ice processing Embodiments of the present invention are directed to non-naturally occurring cells and methods for screening compositions and genes which interact with interleukin 1 beta and interleukin-1 beta converting enzyme (ICE) processing, methods and non-naturally... | 02/13/2001 |
| 5849534 | DNA encoding leukocyte derived growth factor-2 (LDGF-2) A protein, Leukocyte Derived Growth Factor 2 (hereinafter LDGF2) having PDGF-like activity is described. LDGF2 reacts with PDGF receptors and possesses mitogenic and/or chemotactic activity for various cell types, particularly connective tissue cells. LDG... | 12/15/1998 |
