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Attorney: Kramer; Barry


Number of patents: 185
Last date: May 01, 2012

1          
NumberTitleIssue Date
8168056Electrocomposite coatings for hard chrome replacement
The invention provides a method and system for electrolytically coating an article. The method includes providing an article to be coated and disposing the article in an electrolytic cell. The cell includes an anode, a cathode in operable communication with the arti...
05/01/2012
8143393Substituted 4-amino-pyrrolotriazine derivatives useful for treating hyper-proliferative disorders and diseases associated with angiogenesis
This invention relates to novel pyrrozolotriazine compounds, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for treating hyper-proliferative and/or angiogenesis disorders, as a sole agent or in combination with o...
03/27/2012
8138336Pyrrolotriazine derivatives useful for treating cancer through inhibition of aurora kinase
This invention relates to novel compounds and processes for their preparation, methods of treating diseases, particularly Cancer, comprising administering said compounds, and methods of making pharmaceutical compositions for the treatment or prevention of disorders,...
03/20/2012
8133995Substituted 4-amino-pyrrolotriazine derivatives useful for treating hyper-proliferative disorders and diseases associated with angiogenesis
This invention relates to novel pyrrozolotriazine compounds, pharmaceutical compositions containing such compounds and the use of those compounds and compositions for the prevention and/or treatment of hyper-proliferative disorders and diseases associated with angio...
03/13/2012
8129379Substituted 4-amino-pyrrolotriazine derivatives useful for treating hyper-proliferative disorders and diseases associated with angiogenesis
This invention relates to novel pyrrozolotriazine compounds, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for treating hyper-proliferative and/or angiogenesis disorders, as a sole agent or in combination with o...
03/06/2012
8126818Knowledge-management systems for law firms
The present inventors devised unique systems, methods, interfaces, and software for managing and leveraging knowledge in law firms and potentially other enterprises. For example, one system provides a single user interface for researching case law for online legal r...
02/28/2012
8013166Preparation and use of aryl alkyl acid derivatives for the treatment of obesity
This invention relates to certain aryl alkyl acid compounds, compositions, and methods for treating or preventing obesity and related diseases. ...
09/06/2011
7984053System, method, and software for identifying historically related legal cases
The American legal system, judges and lawyers are continually researching an ever-expanding body of past judicial opinions, or case law, for the ones most relevant to resolution of new disputes. To facilitate these searches, some companies collect and publish the ju...
07/19/2011
7943045Reactor with a thermal gradient controlled for the production of pure hydrogen
A device for the thermal separation of water into hydrogen and oxygen, including a closed reaction chamber (1) containing water and, in said reaction chamber: —a heating system including one or several heat source elements (4,11), —one or several m...
05/17/2011
7935254Reactor for simultaneous separation of hydrogen and oxygen from water
We disclose a device for the production of hydrogen from water using heat. The device employs thermal water splitting and works essentially without electricity. It is based on the concept of a membrane reactor with two kinds of membranes allowing the separation of h...
05/03/2011
7837782Yellow inorganic pigments and process for preparing same
The present invention provides yellow inorganic pigments comprising praseodymium, oxides of transition metals selected from molybdenum, titanium, zirconium and combinations thereof, essentially molybdenum, optionally with alkaline earth metal (A) and the said yellow...
11/23/2010
7809738System for determining changes in the relative interest of subjects
A system for determining changes in the interest of a subject over a time period. The system measures the volume of news articles for a subject over a time period and makes a comparison to a previous volume of news articles for the same subject over a previous time ...
10/05/2010
7759376Preparation and use of biphenyl-4-yl-carbonylamino acid derivatives for the treatment of obesity
This invention relates to certain biphenyl-4-yl carbonylamino acid compounds, compositions, and methods for treating or preventing obesity and related diseases. ...
07/20/2010
7750017Heterocycles
This invention relates to novel compounds and processes for their preparation, methods of treating diseases, particularly hyperproliferative diseases such as cancer, comprising administering said compounds, and methods of making pharmaceutical compositions for the t...
07/06/2010
7737153Heteroaryloxy-substituted phenylaminopyrimidines as rho-kinase inhibitors
The invention relates to heteroaryloxy-substituted phenylaminopyrimidines, to methods for the production thereof, and to the use of the same for producing medicaments for the treatment and/or prophylaxis of diseases, especially cardiovascular diseases. The inventive...
06/15/2010
7709491Substituted quinazolines as antiviral agents, especially against cytomegaloviruses
The invention relates to substituted quinazolines and to methods for the production thereof, in addition to the use thereof in the production of medicaments for the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, especially against ...
05/04/2010
7705043Substituted aminodicarboxylic acid derivatives having pharmaceutical properties
The invention relates to compounds of formula (I) and their salts and stereoisomers in which the variables are as defined in the description and claims, for producing medicaments used in the treatment of cardiovascular and ...
04/27/2010
7700653Halogen-substituted aminodicarboxylic acid derivatives
This invention relates to methods for treating cardiovascular disorders selected from heart failure, thromboembolic disorders, venous diseases, and fibriotic disorders other than fibrosis of the liver, comprising administering an effective amount of a compound of fo...
04/20/2010
7695900Method and device for detecting biologically active substances
This application claims a method for detecting biologically active substances, comprising the following steps a) providing a support carrying substances to be tested b) providing a suspension containing luminescent...
04/13/2010
7687510Pyrimidinone derivatives as therapeutic agents against acute and chronic inflammatory, ischaemic and remodelling processes
The invention relates to novel heterocyclic derivatives, processes for their preparation, and their use in medicaments, especially for the treatment of chronic obstructive pulmonary diseases. ...
03/30/2010
7678804Pyrimidine derivatives for treatment of hyperproliferative disorders
Pyrimidine derivatives of formula (I) in which J and Y represent aromatic or heteroaromatic rings; R2, G, G′, and G″ represent substituent groups and R2a represents H or halogen; L represents a lin...
03/16/2010
7662956Tetrahydrobenzo[d]azepin-2-one derivatives and the use thereof for treating cardiovascular diseases
The present application relates to novel tetrahydrobenzo[d]azepin-2-one derivatives, processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for producing medicaments for the treatment and/or prophylaxis of diseases...
02/16/2010
7659412Benzofuran derivatives useful for treating hyper-proliferative disorders
The invention relates to novel benzofuran derivatives, processes for their preparation and their use for preparing medicaments for the treatment or prophylaxis of disorders, especially of hyperproliferative disorders. ...
02/09/2010
7598378Method for the production of 4-(4-aminophenyl)-3-morpholinone
The present invention relates to a process for preparing 4-(4-aminophenyl)-3-morpholinone by reacting 4-(4-nitrophenyl)-3-morpholinone with hydrogen in the presence of a hydrogenation catalyst, characterized in that the reaction is effected in an aliphatic alcohol.
10/06/2009
7589195Tetrahydrobenzo[d]azepin-2-one derivatives and the use thereof for treating cardiovascular diseases
The present application relates to novel tetrahydrobenzo[d]azepin-2-one derivatives, processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for producing medicaments for the treatment and/or prophylaxis of diseases...
09/15/2009
7582666Substituted 2-oxo-3-phenyl-5-carbonylaminomethyl-1,3-oxazolines and their use as anticoagulant and antithrombotics
The invention relates to the field of blood coagulation, more particularly, to novel compounds of general formula (I), to a method for producing the compounds and to their use as active ingredients in medicaments for the pr...
09/01/2009
7582646Pyrimidine derivatives for treatment of hyperproliferative disorders
Pyrimidine derivatives of formula (I) in which J and Y represent aromatic or heteroaromatic rings; R2, G, G′, and G″ represent substituent groups and R2a represents H or halogen; L represents a lin...
09/01/2009
7582645Pyrimidine derivatives for treatment of hyperproliferative disorders
Pyrimidine derivatives of formula (I) in which J and Y represent aromatic or heteroaromatic rings; R2, G, G′, and G″ represent substituent groups and R2a represents H or halogen; L represents a linking group; and M represents CH or N. Pharm...
09/01/2009
75667231-phenyl1-3,4-dihydropyrimidin-2(1H)-one derivatives and their use
The invention relates to novel 1-Phenyl-3,4-dihydropyrimidin-2(1H)-one derivatives having the formula processes for their preparation, and their use in medicaments, especially for the treatment of c...
07/28/2009
7563791Pyrrolotriazine derivatives useful for treating hyper-proliferative disorders and diseases associated with angiogenesis
This invention relates to novel pyrrozolotriazine compounds, pharmaceutical compositions containing such compounds and the use of those compounds and compositions for the prevention and/or treatment of hyper-proliferative disorders and diseases associated with angio...
07/21/2009
7553851Amides of acetic and propionic acids
The invention relates to novel amides of acetic and propionic acids, methods for production and use thereof for the production of medicaments for the treatment and/or prophylaxis of diseases and for improving perception, concentration, learning ability and memory.
06/30/2009
7544709Derivatives of andrimide and moiramide B having antibacterial properties
The invention relates to compounds of general formula (I), to a method for the production thereof, to pharmaceutical compositions containing them, and to their use in the treatment and/or prophlaxis of diseases in humans or animals, particularly bacterial infections...
06/09/2009
7517896Aminodicarboxylic acid derivatives having pharmaceutical properties
The invention relates to compounds of formulae (II), (IV), and (VI) as shown below, wherein the several variable groups are as defined in the specification and claims. Processes for making these materials, and methods for u...
04/14/2009
7517878Heteroarylaminopyrazole derivatives useful for the treatment of diabetes
The present invention relates to heteroarylaminopyrazole compounds, pharmaceutical compositions, and methods for treating diabetes and related disorders. ...
04/14/2009
75145653,5-Difluoropyridines
The invention relates to compounds of the formule ...
04/07/2009
7511048Pyrimidothienoindazoles
The invention relates to novel pyrimidothienoindazoles of formula (I) processes for their preparation and their use for preparing medicaments for the treatment or prophylaxis of disorders, especially of hyperproliferative d...
03/31/2009
7511041Fused azole-pyrimidine derivatives
The present invention relates to hovel fused azolepyrimidine derivatives, processes for preparing them and pharmaceutical preparations containing them. The fused azolepyrimidine derivatives of the present invention exhibit enhanced potency for phosphotidylinositol-3...
03/31/2009
7507714Pituitary adenylate cyclase activating peptide (PACAP) receptor 3 (R3) agonists and their pharmacological methods of use
This invention provides novel peptides that function in vivo to stimulate insulin release from pancreatic beta cells in a glucose-dependent fashion. These insulin secretagogue peptides are shown to stimulate insulin release in rat islet cells in vitro, and in vivo. ...
03/24/2009
7498460Isophthalic acid derivatives
The present invention relates to isophthalic acid derivatives, to a process for their preparation and to their use for producing medicaments for the treatment and/or prophylaxis of diseases in humans and animals, in particular of cardiovascular disorders. ...
03/03/2009
7494978Peptides acting as both GLP-1 receptor agonists and glucagon receptor antagonists and their pharmacological methods of use
The invention provides polypeptides that act both as an agonist of the GLP-1 receptor and an antagonist of the glucagon receptor. Such polypeptides are useful for treating individuals with type 2 diabetes or other metabolic disorders. ...
02/24/2009
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