Did You Know...
...that while attempting to develop a super strong glue, 3M employee Spencer Silver accidentally developed a glue that was so weak it would barely hold two pieces of paper together? However, his colleague Art Fry needed the glue. Fry sang with his church choir and marked the pages of his hymnal with small scraps of paper that often fell out. He used Silver's glue to hold the papers in place. Today we call this invention Post-it Notes.
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| Number | Title | Issue Date |
| 8183435 | Pasture, forage and seed production technology through pod and leaf retention on annuals of the genus (annual medics) The present invention relates to improved cultivars, varieties, lines or plants of annual medics (Medicago genus) wherein the majority of seed pods, upon reaching maturity, remain attached to their respective pedicels. In particular, the present invention rel... | 05/22/2012 |
| 8183249 | Inhibitors of AKT/PKB with anti-tumor activity The subject invention concerns materials and methods for inhibiting the Akt/PKB pathway. In one embodiment, a compound of the invention inhibits kinase activity and/or phosphorylation levels of Akt proteins. The subject invention also concerns methods for inhibiting... | 05/22/2012 |
| 8183225 | Inhibition of bone resorption using medical implants containing adenosine receptor antagonists The invention provides methods and compositions for reducing or inhibiting bone resorption, osteoclast differentiation and stimulation and the loosening of medical prostheses by administering a compound or agent that modulates an adenosine receptor such as the adeno... | 05/22/2012 |
| 8183040 | Methods for in vitro differentiation of Th-17+cells The present invention is directed to an in vitro method for promoting differentiation and proliferation of human T helper lymphocytes that express IL17 (Th-IL17+ cells). The instant method may be used to generate a population of human T helper lymphocytes tha... | 05/22/2012 |
| 8182372 | Device for training athletic or sports ball players The present invention provides a device designed to increase the accuracy of both the throwing, bouncing, propelling by stick and kicking of a baseball, football, lacrosse ball or soccer ball. The apparatus is constructed of a frame, for example of aluminum tubing. ... | 05/22/2012 |
| 8178084 | Pharmaceutical kits comprising mesenchymal stem cells A method of treating a natural soft skeletal tissue injury in a patient the method comprising administering to the patient a composition of mesenchymal stem cells in liquid suspension enriched compared to the natural source of said cells, or tenocytes derived theref... | 05/15/2012 |
| D659911 | Face protector | 05/15/2012 |
| D658947 | Rack | 05/08/2012 |
| 8168667 | Imidazolidine derivatives, uses therefor, preparation thereof and compositions comprising such Compounds of formula (I): wherein X is O or S, R1 is acyl, aldehyde, cycloalkyl, an optionally substituted alkyl, alkenyl or alkynyl, R2 is H, alkyl, hydroxyalkyl... | 05/01/2012 |
| 8163901 | Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same Compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals ... | 04/24/2012 |
| 8163748 | s-Triazine compounds, pharmaceutical compositions and method of using the same Novel s-triazine compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of condi... | 04/24/2012 |
| 8153651 | Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same Compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals ... | 04/10/2012 |
| 8151970 | Orienting and feeding apparatus for manufacturing line The present improvement is useful for orienting and feeding blow molded preforms. Cylindrical preforms have larger threaded necks with larger encircling discs below the necks. A pair of belts is provided for conveying objects downstream. The gap between these belts ... | 04/10/2012 |
| 8150241 | Baseboard heater security device The present invention relates to a baseboard heater guard or security device designed to shield the upper and front surfaces of a baseboard heater. The guard or security device comprises two or more vertical members that substantially follow the contour of the outsi... | 04/03/2012 |
| 8141433 | Leak detector A method of measuring the gas flow of an incondensable gas in a flowing mixture of said incondensable gas and a condensable gas comprising the steps of calibrating a leak detector; injecting a known quantity of gauge gas at a known mass flow rate into said flowing m... | 03/27/2012 |
| D655869 | Visor for use with a hair dryer | 03/13/2012 |
| D655568 | Milk frother | 03/13/2012 |
| 8128907 | CSF biomarker dilution factor corrections by MRI imaging and algorithm A method is disclosed for providing a correcting factor for the dilution of measurements of at least one biomarker in cerebrospinal fluid (CSF). The method comprises providing semi-automated measurements of the ventricular system by MRI scans using quantitative anat... | 03/06/2012 |
| 8122576 | Positioning, handling and assembling system for manufacture of aeronautical parts The system has special application in the manufacture of aircraft wing covers (10 made of carbon fiber and the stringers (3) cured jointly with the wing cover during the polymerization in autoclave. The tool pieces (4) being used are defined by ... | 02/28/2012 |
| 8110181 | Method of treating with interferons A method of treating tuberculosis comprising administering an aerosolized interferon such as interferon α, interferon β or interferon γ in a therapeutically effective amount is provided herein. Also, pharmaceutical compositions of one or more aerosolized i... | 02/07/2012 |
| D653606 | Tyre | 02/07/2012 |
| 8105585 | Ply-GBS mutant lysins Methods, compositions and articles of manufacture useful for the treatment of various Group B streptococci (GBS) bacteria using various lysins, including certain PlyGBS mutant lysins, are provided. ... | 01/31/2012 |
| 8105572 | Method of treating tuberculosis with interferons A method of treating tuberculosis comprising administering an aerosolized interferon such as interferon α, interferon β or interferon γ in a therapeutically effective amount is provided herein. Further, a method of reducing the infectivity of tuberculosis or redu... | 01/31/2012 |
| 8105571 | Method of treating pulmonary disease with interferons A method of treating a pulmonary disease such as, for instance idiophathic pulmonary fibrosis (IPF), mixed connective tissue disease and asthma, comprising administering an aerosolized interferon such as interferon γ in a therapeutically effective amount is provide... | 01/31/2012 |
| 8105423 | Process and system for separating finely aerosolized elemental mercury from gaseous streams A method and apparatus for practicing the method are provided for separating droplets of finely aerosolized elemental mercury from a gaseous stream in which the droplets are dispersed. In the method a gold plated metallic capillary surface is contacted with the gase... | 01/31/2012 |
| 8093265 | Bicycloheteroaryl compounds as P2X7 modulators and uses thereof Compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals ... | 01/10/2012 |
| 8088764 | Compound useful for the treatment of degenerative and inflammatory diseases A novel compound able to inhibit JAK is disclosed, that comprises a compound according to Formula I: or a pharmaceutically acceptable salt thereof. The compound may be prepared as a pharmaceutical composition, and may be us... | 01/03/2012 |
| 8084034 | Proteins The present invention provides new polypeptides. Said polypeptides are of use in the screening, diagnosis and prognosis of B-cell non-Hodgkin's lymphoma, breast cancer, colorectal cancer, gastric cancer, hepatocellular carcinoma, lung cancer, lymphoid leukaemia (par... | 12/27/2011 |
| 8083156 | Dispersion lance and shield for dispersing a treating agent into a fluid stream A dispersion apparatus for dispersing a treating agent into a fluid treatment system that includes a flow duct in which a fluid stream flowing through the duct is mixed with the treating agent. The apparatus is based on a multi-pipe lance positioned in the stream fl... | 12/27/2011 |
| D650971 | Baby bib | 12/27/2011 |
| 8079601 | Prefabricated complex joint sealer A sealing member for sealing over a structural joint or compound expansion joint. The sealing member has an elastomeric portion to overlie the lines of the joint and an adhesive receiving region to the sides of the elastomeric portion. The adhesive receiving region ... | 12/20/2011 |
| 8076345 | 2-cyanophenyl-7,8-dihydro-5H-pyrido[4,3-d]pyrimidine compounds, compositions and uses thereof Fused heterocyclic compounds are provided according to formula 1: where R1, R2, R3, and m are as defined herein. Provided compounds and pharmaceutical compositions thereof are useful for the... | 12/13/2011 |
| 8067156 | Method for generating replication defective viral vectors that are helper free Sequences are provided that are capable of directing circular adeno-associated virus replication, useful in vectors for providing therapeutic agents to a subject in need thereof. The vectors of the invention are particularly useful in the treatment of acute medical ... | 11/29/2011 |
| 8062517 | System for removal of contaminants from industrial streams A method and system for removing from an aqueous system which is contaminated therewith: (1) mercury present as colloids, ions and/or organically bound compounds, and (2) hydrocarbons solubilized, dispersed, and/or emulsified in the said system. Pursuant to the inve... | 11/22/2011 |
| 8038635 | Forward head posture correction collar A forward head position correction collar is provided which in combination includes a shoulder collar assembly, a chin mastoid piece for engaging and positioning the head of a wearer of the collar; and interconnecting means for interconnecting the chin piece to the ... | 10/18/2011 |
| 8021838 | Transcriptional regulation of target genes The present invention describes a method of identifying inducible genetic regulatory sequences that can control the transcription of specific gene transcripts. Methods of using inducible genetic regulatory sequences are also discussed. In particular, the genetic reg... | 09/20/2011 |
| 8021282 | Exercise device An improved exercise device in the nature of a kettlebell. The device has a frame covered by a shroud that is configured to lessen the impact of the device on the user. There are a plurality of weights that can be easily attached and detached from the frame to incre... | 09/20/2011 |
| 8016350 | Vehicle seat for reducing the risk of spinal and head injuries of personnel in combat vehicles A vehicle seat for use in military vehicles provides increased protection for a helmeted or unhelmeted combatant soldier. The seat includes a seat portion having a layer of high impact energy absorbing material. A back support portion adjoined to the rear of the sea... | 09/13/2011 |
| D645067 | Belt guard for a flotation cell | 09/13/2011 |
| 8012983 | Substituted triazolopyrazines useful for the treatment of degenerative and inflammatory diseases Novel [1.2.4]triazolo[1,5-a]pyrazine and imidazo[1,2-a]pyrazine compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the... | 09/06/2011 |
