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Attorney: King & Spalding, LLP


Number of patents: 73
Last date: February 07, 2012

1    
NumberTitleIssue Date
8109776Two-material separable insulated connector
Stiff and soft materials each provide certain advantages when used in the manufacture of separable insulated connectors, such as elbow and T-body connectors. Utilizing a shell or an insert that includes one section made from a stiff material and one section made fro...
02/07/2012
8109014Foot orthotic devices
A foot orthotic device is disclosed. More specifically described is an individualized foot orthotic device to correct and/or restore the ideal alignment and/or positioning of foot structures. The device is designed using a method and system that applies sequential p...
02/07/2012
7993034Reflector having inflection point and LED fixture including such reflector
A recessed light fixture includes an LED light source and a reflector extending 360 degrees around a center line of light output from the light source. A cross-sectional geometry of the reflector includes a bell-shaped curve with two radii of curvature that join tog...
08/09/2011
7531561GSK-3 inhibitors
Provided are thiadiazolidine compounds of formula I wherein R1 is an organic group having at least 8 atoms selected from C or O, which is not linked directly to the N through a —C(O)— and comprising at least ...
05/12/2009
7521478Total synthesis of myriaporones
Compounds of the general formula (I) or a pharmaceutically acceptable salt, derivative, prodrug or stereoisomer thereof are provided: wherein the substituent groups defined by R are each independently selected from the group consisting of H, SiR′3, SORâ...
04/21/2009
7507872Transgenic toll-like receptor 9 (TLR9) mice
The present invention provides a receptor protein specifically recognizing bacterial DNA having an unmethylated CpG sequence, a genomic DNA encoding it, an experimental animal model useful for examining responsiveness of a host immune cell against a bacterial infect...
03/24/2009
7507708Antitumoral compounds
The present invention is directed to new kahalalide antitumoral compounds, in particular to analogues of kahalalide F, useful as antitumoral, antiviral, antifungal agents and in the treatment of psoriasis. ...
03/24/2009
7482429Kahalalide F and related compounds
A process is provided for preparing kahalalide F and which leads to other kahalalide mimic compounds having useful biological activity. ...
01/27/2009
7419009Apparatus for radially expanding and plastically deforming a tubular member
An apparatus and method according to which a tubular member is radially expanded and plastically deformed. ...
09/02/2008
7396837Antitumoral analogs of lamellarins
New lamellarins are provided of the general formula III or a pharmaceutically acceptable salt, derivative, prodrug or stereoisomer thereof ...
07/08/2008
7368284Porcine CMP-N-Acetylneuraminic acid hydroxylase gene
The present invention provides porcine CMP-N-Acetylneuraminic-Acid Hydroxylase (CMP-Neu5Ac hydroxylase) protein, cDNA, and genomic DNA regulatory sequences. Furthermore, the present invention includes porcine animals, tissues, and organs, as well as cells and cell l...
05/06/2008
7363691Method and apparatus for forming a mono-diameter wellbore casing
A mono-diameter wellbore casing. The mono-diameter wellbore casing is formed by plastically deforming and radially expanding a first tubular member within a wellbore. A second tubular member is then plastically deformed and radially expanded in overlapping relation ...
04/29/2008
7363690Method and apparatus for forming a mono-diameter wellbore casing
A mono-diameter wellbore casing. The mono-diameter wellbore casing is formed by plastically deforming and radially expanding a first tubular member within a wellbore. A second tubular member is then plastically deformed and radially expanded in overlapping relation ...
04/29/2008
7360591System for radially expanding a tubular member
A system for radially expanding a tubular member. ...
04/22/2008
7350564Mono-diameter wellbore casing
A mono-diameter wellbore casing. A tubular liner and an expansion cone are positioned within a new section of a wellbore with the tubular liner in an overlapping relationship with a pre-existing casing. A hardenable fluidic material is injected into the new section ...
04/01/2008
7348311Derivatives of dehydrodidemnin B
Dehydrodidemnin B with useful biological activity has formula (1). It can be isolated from natural sources or synthesized, and it forms active derivatives ...
03/25/2008
7341744Method of treating secretory diarrhea with enteric formulations of proanthocyanidin polymer
Pharmaceutical compositions containing a proanthocyanidin polymer composition which are useful for the treatment and prevention of secretory diarrhea are provided. The invention specifically relates to pharmaceutical formulations of a proanthocyanidin polymer compos...
03/11/2008
7323444Use of kahalalide compounds for the manufacture of a medicament for the treatment of psoriasis
Kahalalide compounds, in particular kahalalide F, are of use in a method to treat a mammal suffering from skin disease with avoiding toxicity and leading to clinical improvement. ...
01/29/2008
7323195Enteric formulations of proanthocyanidin polymer antidiarrheal compositions
Pharmaceutical compositions containing a proanthocyanidin polymer composition which are useful for the treatment and prevention of secretory diarrhea are provided. The invention specifically relates to pharmaceutical formulations of a proanthocyanidin polymer compos...
01/29/2008
7309601Sequences from an endosymbiont and their uses
rDNA corresponding to an endosymbiotic bacteria associated with Ecteinascidia turbinata has been identified. The bacterium appears to be responsible for the biosynthesis of ecteinascidin compounds. The 16S rDNA sequence corresponding to Candidatus Endo...
12/18/2007
7291726Process for the preparation of 2′-halo-β-L-arabinofuranosyl nucleosides
The present invention is directed to the process for the preparation of 2′-deoxy-2′-halo-β-L-arabinofuranosyl nucleosides, and in particular, 2′-deoxy-2′-fluoro-β-L-arabinofuranosyl thymine (L-FMAU), from L-arabinose, which is commercially available and le...
11/06/2007
7290605Seal receptacle using expandable liner hanger
The end of an expandable liner hanger (120) provides a receptacle for another tubular liner (135). ...
11/06/2007
RE39887Dehydrodidemnin B
Dehydrodidemnin B with useful biological activity has formula (1). It can be isolated from natural sources or synthesized, and it forms active derivatives. ...
10/16/2007
7256351Jacket construction having increased flame resistance
A communications cable having increased fire resistance and reduced attenuation and crosstalk includes a core having at least one insulated electrical conductor, and a jacket having an inner surface and a plurality of ribs projecting radially inward from the inner s...
08/14/2007
7240677System and method for force, displacement, and rate control of shaped memory material implants
Controlling the transformation of the microstructure of shape memory material implants. A surgeon can use the inventive energy delivery device to control the rate of implant shape change, the extent of implant shape change, as well as the force exerted on the surrou...
07/10/2007
7228899Warning device and method to prevent clutch burning
This invention is generally directed towards a system designed to assist the rig operator by alerting him/her that the air pressure is too low to be using the drum clutch, to provide a log for studies on rig operation technique, and to provide a training tool for ri...
06/12/2007
7192936Modified 2′ and 3′-nucleoside prodrugs for treating Flaviviridae infections
2′ and/or 3′ prodrugs of 1′, 2′, 3′ or 4′-branchednucleosides, and their pharmaceutically acceptable salts and derivatives are described. These prodrugs are useful in the prevention and treatment of Flaviviridae infections, including HCV infection, and o...
03/20/2007
7129213Tripeptides and tripeptide derivatives for the treatment of neurodegenerative diseases
The invention relates to the use of specific tripeptides for the treatment of neurodegenerative diseases, and to pharmaceutical compositions comprising the tripeptides. The tripeptide derivatives satisfy the following formula (I): wherein X represents OH, (C1-5...
10/31/2006
7084574Fluorescent light power source for supplying power to an external device
Systems and methods are provided for deriving power for an external device from the power source of a fluorescent light. The power source includes a fluorescent ballast electrically connected to the connectors of a light fixture for receiving an input voltage and fo...
08/01/2006
7053100Therapeutic nucleosides
The use of a 1,3-oxathiolane nucleoside analogue and pharmaceutically acceptable derivatives thereof for the treatment of hepatitis B virus infections is disclosed. Pharmaceutical formulations are also provided. ...
05/30/2006
7029422Ergonomics safety warning device and method to prevent clutch burning
This invention will therefore provide a tool to assist the rig operator in perfecting his/her rig operation skills. Disclosed herein is an apparatus and method for minimizing slippage on the drum clutch of a well service rig. A detector senses the motion of the comp...
04/18/2006
7006920Activity data capture system for a well service vehicle
The present invention is directed to incrementing a well service rig in such a manner that activity-based and/or time-based data for the well site is recorded. The acquired data can be transmitted via wired, wireless, satellite or physical to a data center preferabl...
02/28/2006
7004456Engine speed limiter for a hoist
A mobile service rig for wells includes a hoist powered by an internal combustion engine. In response to the hoist exerting a predetermined lifting force, the lifting force is limited by automatically limiting or reducing the speed of the engine. ...
02/28/2006
6979561Non-homogeneous systems for the resolution of enantiomeric mixtures
The present invention relates to a process for the biocatalyst-mediated enantioselective conversion of enantiomeric mixtures of hydrophobic esters uing a biphasic solvent system. More particularly, the present invention relates to the enzyme-mediated enantioselectiv...
12/27/2005
6960683Salt forms of poorly soluble probucol esters and ethers
Organic amine salts of compounds of the formula: and their pharmaceutically acceptable salts, and uses in medical therapy are provided. ...
11/01/2005
6939965Process of manufacture of 1,3-oxathiolane nucleosides using titanium trichloride mono-isopropoxide
Processes for the preparation of 1,3-oxathiolane nucleosides are provided that include reacting a 5-O-protected-oxymethyl-1,3-oxathiolane with a silylated nucleoside in the presence of (Cl)3Ti(isopropoxide). Using the processes described herein, the compo...
09/06/2005
6927291Method for the synthesis of 2′,3′-dideoxy-2′,3′-didehydronucleosides
An efficient synthetic route to antiviral 2′,3′-dideoxy-2′,3′-didehydro-nucleosides, such as 2′,3′-dideoxy and 2′- or 3′-deoxyribo-nucleoside analogs, from available precursors is disclosed, with the option of introducing functionality as needed. In ...
08/09/2005
6914054Methods and compositions for treating hepatitis C virus
A method and composition for treating a host infected with hepatitis C comprising administering an effective hepatitis C treatment amount of a described 1′, 2′ or 3′-modified nucleoside or a pharmaceutically acceptable salt or prodrug thereof, is provided....
07/05/2005
69114242′-fluoronucleosides
A class of 2′-fluoro-nucleoside compounds are disclosed which are useful in the treatment of hepatitis B infection, hepatitis C infection, HIV and abnormal cellular proliferation, including tumors and cancer. The compounds have the general formulae:
06/28/2005
6908924N4-acylcytosine-1,3-dioxolane nucleosides for treatment of viral infections
The present invention is directed to a compound, method and composition of treating or preventing viral infections, in particular, human immunodeficiency virus (HIV) and hepatitis B virus (HBV) infections, in human patients or other animal hosts, comprising the admi...
06/21/2005
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