A kissing shield comprised of a thin, flexible membrane and a frame or holder.
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| Number | Title | Issue Date |
| 7671035 | Epidermal growth factor receptor antisense oligonucleotides Disclosed are synthetic oligonucleotides complementary to nucleic acids encoding epidermal growth factor and methods of their use. ... | 03/02/2010 |
| 7632822 | Modulation of immunostimulatory properties of oligonucleotide-based compounds by utilizing modified immunostimulatory dinucleotides The invention relates to the therapeutic use of oligonucleotides as immunostimulatory agents in immunotherapy applications. More particularly, the invention provides immunomers and an immunostimulatory oligonucleotides for use in methods for generating an immune res... | 12/15/2009 |
| 7569554 | Synergistic treatment of cancer using immunomers in conjunction with therapeutic agents The invention relates to the therapeutic use of immunostimulatory oligonucleotides and/or immunomers in combination with chemotherapeutic agents to provide a synergistic therapeutic effect. ... | 08/04/2009 |
| 7566702 | Immunostimulatory oligonucleotide multimers The invention provides an immunostimulatory nucleic acid. In certain embodiments according to this aspect of the invention, the sequence of the immunostimulatory oligonucleotide and/or immunomer is at least partially self-complementary. ... | 07/28/2009 |
| 7517862 | Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5′ ends The invention relates to the therapeutic use of oligonucleotides as immunostimulatory agents in immunotherapy applications. More particularly, the invention provides immunomers for use in methods for generating an immune response or for treating a patient in need of... | 04/14/2009 |
| 7498426 | Immunostimulatory oligonucleotide multimers The invention provides an immunostimulatory nucleic acid. In certain embodiments according to this aspect of the invention, the sequence of the immunostimulatory oligonucleotide and/or immunomer is at least partially self-complementary. ... | 03/03/2009 |
| 7498425 | Immunostimulatory oligonucleotide multimers The invention provides an immunostimulatory nucleic acid. In certain embodiments according to this aspect of the invention, the sequence of the immunostimulatory oligonucleotide and/or immunomer is at least partially self-complementary. ... | 03/03/2009 |
| 7470674 | Immunostimulatory properties of oligonucleotide-based compounds comprising modified immunostimulatory dinucleotides The invention relates to the therapeutic use of oligonucleotides as immunostimulatory agents in immunotherapy applications. More particularly, the invention provides an immunostimulatory oligonucleotides for use in methods for generating an immune response or for tr... | 12/30/2008 |
| 7427405 | Immunostimulatory oligonucleotide multimers The invention provides an immunostimulatory nucleic acid. In certain embodiments according to this aspect of the invention, the sequence of the immunostimulatory oligonucleotide and/or immunomer is at least partially self-complementary. ... | 09/23/2008 |
| 7407944 | Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5′ ends The invention relates to the therapeutic use of oligonucleotides as immunostimulatory agents in immunotherapy applications. More particularly, the invention provides immunomers for use in methods for generating an immune response or for treating a patient in need of... | 08/05/2008 |
| 7405285 | Immunostimulatory oligonucleotide multimers The invention provides an immunostimulatory nucleic acid. In certain embodiments according to this aspect of the invention, the sequence of the immunostimulatory oligonucleotide and/or immunomer is at least partially self-complementary. ... | 07/29/2008 |
| 7354907 | Short immunomodulatory oligonucleotides The invention relates to modulation of the immune system. More particularly, the invention relates to modulating the immune system through the use of oligonucleotide-derived compounds. The invention provides immunostimulatory agents that are less expensive to make t... | 04/08/2008 |
| 7288567 | Inhibitors of histone deacetylase The invention relates to the inhibition of histone deacetylase. The invention provides compounds and methods for inhibiting histone deacetylase enzymatic activity. The invention also provides compositions and methods for treating cell proliferative diseases and cond... | 10/30/2007 |
| 7276489 | Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5′ ends The invention relates to the therapeutic use of oligonucleotides as immunostimulatory agents in immunotherapy applications. More particularly, the invention provides immunomers for use in methods for generating an immune response or for treating a patient in need of... | 10/02/2007 |
| RE39850 | Inhibitors of histone deacetylase The invention relates to the inhibition of histone deactylase. The invention provides compounds and methods for inhibiting histone deacetylase enzymatic activity. The invention also provides compositions and methods for treating cell proliferative diseases and condi... | 09/18/2007 |
| 7241456 | Formulations for topical delivery of bioactive substances and methods for their use The invention relates to topical delivery of bioactive agents. More particularly, the invention relates to anhydrous formulations for percutaneous absorption. The invention provides formulations that allow efficient topical delivery of high concentrations of bioacti... | 07/10/2007 |