Actor Marlon Brando has four patents, all named "Drumhead tensioning device and method."
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| Number | Title | Issue Date |
| 8153430 | Methods related to surgery The invention is directed to methods related to surgery, for example gastrointestinal surgery. In particular, the invention is methods of treating fistulae, promoting accelerated healing of anastomoses and preventing failure of anastomoses. Such methods utilize nove... | 04/10/2012 |
| 8153423 | Pluripotent cells from the mammalian late epiblast layer This invention relates to the isolation and propagation of pluripotent cells isolated from the mammalian late epiblast layer, termed Epiblast Stem Cells' (EpiSCs). These cells are useful in a range of applications, including the generation of transgenic animal speci... | 04/10/2012 |
| 8088732 | Compositions comprising physiologic concentrations of cytokines The invention is directed to novel cellular factor-containing solution compositions (referred to herein as “CFS” compositions), including novel sustained-release cellular factor-containing solution compositions (referred to herein as “SR-CFS” compositions), ... | 01/03/2012 |
| 8058066 | Cellular factor-containing solution compositions The invention is directed to novel cellular factor-containing solution compositions (referred to herein as “CFS” compositions), including novel sustained-release cellular factor-containing solution compositions (referred to herein as “SR-CFS” compositions), ... | 11/15/2011 |
| 5955290 | Assay systems using the CNTF signal transduction pathway The present invention provides for a stable, biologically active CNTF/receptor complex, and hybrids or mutants thereof. The invention is also based in part on the discovery that the CNTF/receptor complex promotes differentiation through a signal transduct... | 09/21/1999 |
| 5892003 | Ciliary neurotrophic factor receptor antibodies The present invention relates to the ciliary neurotropic factor (CNTF) receptor, and provides for CNTF receptor antibodies. It also relates to diagnostic techniques for identifying CNTF-related neurologic conditions.... | 04/06/1999 |
| 5889173 | DNA encoding multifunctional neurothrophic factors Neurotrophins having activities of multiple parental neurotrophins are described, as well as DNA for their production and pharmaceutical preparations thereof.... | 03/30/1999 |
| 5849897 | Nucleic acid molecule encoding ciliary neurotrophic factor receptor The present invention relates to the ciliary neurotrophic factor (CNTF) receptor, and provides for CNTF receptor nucleic acid and amino acid sequences. It also relates to (i) assay systems for detecting CNTF activity; (ii) experimental model systems for s... | 12/15/1998 |
| 5843749 | Ehk and Ror tyrosine kinases The present invention provides for novel receptor tyrosine kinases known as Ror-1, Ror-2, Ehk-1 and Ehk-2. The invention also provides for assay systems that may be used to detect and/or measure neurotrophin activity or to identify agents that exhibit neu... | 12/01/1998 |
| 5705617 | Neurotrophic factors having altered receptor binding specificities A method of altering the receptor binding properties and the stability of neurotrophic factors is set forth. Mutant neurotrophic factors having altered receptor binding specificities are described. Specific embodiments include neurotrophic factors that bi... | 01/06/1998 |
| 5688911 | Trk neurotrophin binding motifs Trk neurotrophin binding motifs consisting of 24 amino acid, leucine rich domains are described as well as nucleic acid sequences encoding such peptides. The leucine rich motifs are useful in screens for novel agonists and antagonists of the neurotrophins... | 11/18/1997 |
| 5667968 | Prevention of retinal injury and degeneration by specific factors Photoreceptor injury or cell death (retinal degeneration) is prevented by the introduction into the living mammalian eye of specific, survival-promoting factors. These specific factors prevent damage and degeneration of photoreceptors when introduced into... | 09/16/1997 |
| 5622862 | Assay systems for trkB neurotrophin activity The present invention provides for assay systems that may be used to detect and/or measure neurotrophin activity or to identify agents that exhibit neurotrophin-like activity, and for methods of using such assay systems. It is based, at least in part, on ... | 04/22/1997 |
| 5512661 | Multitrophic and multifunctional chimeric neurotrophic factors The present invention relates to chimeric neurotrophic factors which comprise at least a portion of a naturally occurring cellular factor and a portion of at least one other molecule such that the resulting chimeric molecule has neurotrophic activity. It ... | 04/30/1996 |
| 5488099 | Multifunctional chimeric neurotrophic factors Neurotrophins having activities of multiple parental neurotrophins are described, as well as DNA for their production and pharmaceutical preparations thereof.... | 01/30/1996 |
| 5470952 | CNTF and IL-6 antagonists Heterodimer proteins comprising a soluble specificity determining cytokine receptor component and the extracellular domain of a ଲ receptor component function as CNTF and IL-6 antagonsists.... | 11/28/1995 |
| 5360740 | Assay system for degenerative muscle disease An assay system useful for detecting denervated or degenerating muscle by measuring the amount of soluble ciliary neurotrophic factor receptor in body fluids is described.... | 11/01/1994 |
| 5349055 | Nerve growth factor having altered receptor binding specificities A method of altering the receptor binding properties and the stability of neurotrophic factors is set forth. Mutant neurotrophic factors having altered receptor binding specificities are described. Specific embodiments include neurotrophic factors that bi... | 09/20/1994 |
| 5332672 | Prevention of ES cell differentiation by ciliary neurotrophic factor The present invention provides for a stable, biologically active CNTF/receptor complex, and hybrids or routants thereof. The invention is also based in part on the discovery that the CNTF/receptor complex promotes differentiation through a signal transduc... | 07/26/1994 |