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| Number | Title | Issue Date |
| 8178835 | Prolonged ion resonance collision induced dissociation in a quadrupole ion trap A technique is disclosed for conducting collision induced dissociation (CID) in a quadrupole ion trap (QIT) having higher order field components. In order to compensate for the shift in the frequency of motion with amplitude of the excited ions arising from the infl... | 05/15/2012 |
| 8168943 | Data-dependent selection of dissociation type in a mass spectrometer Methods and apparatus for data-dependent mass spectrometric MS/MS or MSn analysis are disclosed. The methods may include determination of the charge state of an ion species of interest, followed by automated selection of a dissociation type (e.g., CAD, ET... | 05/01/2012 |
| 8164066 | Magnetic lens, method for focusing charged particles and charged particle energy analyzer The invention provides a magnetic lens for generating a magnetic imaging field to focus charged particles emitted from a sample, the lens comprising a central pole piece and an outer pole piece disposed about the central pole piece, wherein the lens comprises a magn... | 04/24/2012 |
| 8153963 | Mass spectrometer This invention relates to mass spectrometers comprising a reaction cell and where mass spectra are collected both from unreacted ions and also from reaction product ions. In particular, although not exclusively, this invention finds use in tandem mass spectrometry w... | 04/10/2012 |
| 8148680 | Ion transfer arrangement with spatially alternating DC and viscous ion flow A method of transporting gas and entrained ions between higher and lower pressure regions of a mass spectrometer comprises providing an ion transfer conduit 60 between the higher and lower pressure regions. The ion transfer conduit 60 includes an elect... | 04/03/2012 |
| 8148679 | Efficient atmospheric pressure interface for mass spectrometers and method An ion transfer arrangement for transporting ions between higher and lower pressure regions of the mass spectrometer comprises an ion transfer conduit 60. The conduit 60 has an inlet opening towards a relatively high pressure chamber 40 and an o... | 04/03/2012 |
| 8141411 | Method for determining a low cylinder pressure condition for a gas chromatograph A method for determining a low cylinder pressure condition of a gas chromatograph includes providing gas from the cylinder to an inlet of the gas chromatograph. In particular, the gas is provided at a predetermined inlet pressure that is higher than an inlet pressur... | 03/27/2012 |
| 8119984 | Method and apparatus for generation of reagent ions in a mass spectrometer A front-end reagent ion source for a mass spectrometer is disclosed. Reagent vapor is supplied to a reagent ionization volume located within a chamber of the mass spectrometer and maintained at a low vacuum pressure. Reagent ions are formed by interaction of the rea... | 02/21/2012 |
| 8110993 | Methods for inductively-coupled RF power source A method for tracking a variable resonance condition in a plasma coil during creation of plasma from a gas flowing in a plasma torch adjacent to the plasma coil comprises: providing a radio-frequency (RF) power source comprising a power amplifier that generates a ra... | 02/07/2012 |
| 8093554 | Multi-channel detection A mass spectrometer and method of mass spectrometry wherein charged particles in a beam undergo multiple changes of direction. A detection arrangement detects a first portion of the charged particle beam, and provides a first output based upon the intensity of the d... | 01/10/2012 |
| 8030613 | RF power supply for a mass spectrometer The present invention provides a radio frequency (RF) power supply in a mass spectrometer. The power supply provides an RF signal to electrodes of a storage device to create a trapping field. The RF field is usually collapsed prior to ion ejection. In an illustrativ... | 10/04/2011 |
| 8022349 | Linear sensor array for an optical spectroscopy device and methods of use thereof Time-resolved analysis of a spectrum is performed by illuminating a one-dimensional array of charge-transfer device light-sensitive pixel cells and periodically non-destructively copying charges in the light-sensitive cells to respective storage cells (“row storag... | 09/20/2011 |
| 8018514 | Charge injection device camera system for radiation-hardened applications An imaging system for deployment within a high-radiation environment. The imaging system has an imaging array of photosensitive pixels, each of which contains a sense gate for integrating photogenerated charge during the course of a frame and an amplifier transistor... | 09/13/2011 |
| 8017909 | Ion trap An ion trap comprises substantially elongate electrodes 10, 20 some of which are curved along their axis of elongation and which define a trapping volume between them. The sectional area of this trapping volume towards the extremities of the trap in the direc... | 09/13/2011 |
| 7999223 | Multiple ion isolation in multi-reflection systems This invention relates to a method of operating a charged particle trap in which ions undergo multiple reflections back and forth and/or follow a closed orbit around, usually, a set of electrodes. The invention allows high-performance isolation of multiple ion speci... | 08/16/2011 |
| 7990241 | Encapsulated switches employing mercury substitute and methods of manufacture thereof Encapsulated switches are disclosed which substitute non-toxic gallium alloy for mercury. In one embodiment, wetting of the interior surfaces of the housing is prevented by coating the surfaces with an electrically insulative inorganic non-metallic material, such as... | 08/02/2011 |
| 7987060 | Identifying peaks in mass spectrometry data A method of processing Fourier Transform Mass Spectrometry (FTMS) data includes performing a Fourier Transform of a part of a time domain transient and identifying from that transformed data signal peaks representative of the presence of ions. After peak identificat... | 07/26/2011 |
| 7985950 | Parallel mass analysis A system and method of mass spectrometry is provided. Ions from an ion source are stored in a first ion storage device and in a second ion storage device. Ions are ejected from the first ion storage device to a first mass analysis device during a first ejection time... | 07/26/2011 |
| 7983386 | X-ray analysis instrument An apparatus for carrying out both x-ray diffraction (XRD) and x-ray fluorescence (XRF) analysis of a crystalline sample. A sample holder is located within an evacuable chamber. An x-ray fluorescence source and separate x-ray diffraction source are mounted within th... | 07/19/2011 |
| 7982183 | Ion transfer tube with spatially alternating DC fields An ion transfer arrangement for transporting ions between higher and lower pressure regions of a mass spectrometer includes an electrode assembly (120) with a first plurality of ring electrodes (205) arranged in alternating relation with a second plura... | 07/19/2011 |
| 7962301 | Method of processing and storing mass spectrometry data A data compression technique is disclosed for Fourier Transform Mass Spectrometry (FTMS). A statistical analysis is applied to the data in the frequency domain since most of this data is a result of randomly distributed electronic noise. A fit of the whole frequency... | 06/14/2011 |
| 7947948 | Two-dimensional radial-ejection ion trap operable as a quadrupole mass filter A two-dimensional radial-ejection ion trap is constructed from four apertured electrodes having inwardly facing hyberbolic surfaces, with each electrode being spaced from the centerline by a distance r that is greater than the hyperbolic radius r0 defined... | 05/24/2011 |
| 7943899 | Method and apparatus for identifying the apex of a chromatographic peak A technique for mass spectrometry includes: receiving first time domain data generated from a chromatographic output, the first time domain data including mass spectra; extracting second time domain data from the first time domain data, the second time domain data c... | 05/17/2011 |
| 7940008 | Inductively-coupled RF power source A system and method are disclosed for implementing a power source including a power amplifier that generates a radio-frequency power signal with an adjustable operating frequency. The power amplifier also generates a reference phase signal that is derived from the r... | 05/10/2011 |
| 7933379 | Measurement of lead by X-ray fluorescence A method, instrument, and computer program software product for characterizing a sample with respect to the presence of a specified element, either as a constituent of a surface layer or of the bulk of the sample. Intensities of fluorescent emission at two character... | 04/26/2011 |
| 7932487 | Mass spectrometer with looped ion path A mass spectrometer includes at least one ion selector, at least one collision cell, and an ion path switching device arranged to define a looped ion path around which ions derived from a sample may be sent multiple times (without reversal of ion travel) in order to... | 04/26/2011 |
| 7928373 | Isolating ions in quadrupole ion traps for mass spectrometry Ions in a predefined narrow mass to charge ratio range are isolated in an ion trap by adjusting the field and using ejection frequency waveform(s). The ejection waveforms have frequency components in a first and a second dimension, and, are applied across electrodes... | 04/19/2011 |
| 7916834 | Small spot X-ray fluorescence (XRF) analyzer A hand-held, self-contained x-ray fluorescence (XRF) analyzer produces a small x-ray spot on a sample to interrogate the elemental composition of a sample region of millimeter-size characteristic dimension. The analyzer includes a collimator for aiming an x-ray beam... | 03/29/2011 |
| 7899153 | Automated x-ray fluorescence analysis A method for classifying a sample based upon a complete spectral analysis. The sample is illuminated with penetrating radiation and an initial complete spectral analysis is performed based on spectral resolution of resonant fluorescence lines emitted at the surface,... | 03/01/2011 |
| 7897405 | Method for identifying the elution time of an analyte A method for determining a time of elution of a peptide of interest from a liquid chromatography column includes a step of obtaining chromatographic data for each of a plurality of candidate fragment ions of the peptide of interest. A time along a common chromatogra... | 03/01/2011 |
| 7880136 | Multiple ion injection in mass spectrometry This invention relates to mass spectrometry that includes ion trapping in at least one of the stages of mass analysis. In particular, although not exclusively, this invention relates to tandem mass spectrometry where precursor ions and fragment ions are analysed. A ... | 02/01/2011 |
| 7847243 | Ion trapping This invention relates to a method of trapping ions and to an ion trapping assembly. In particular, the present invention has application in gas-assisted trapping of ions in an ion trap prior to a mass analysis of the ions in a mass spectrometer. The invention provi... | 12/07/2010 |
| 7875847 | Docking stand for analytical instrument An analytical instrument may be docked in a stand. The stand provides electrical power, cooling, gas to purge air from an analytical gap within the instrument and/or other supplies or services to the instrument. The stand contains a contactless memory, such as an RF... | 01/25/2011 |
| 7872749 | Instrument for making optical measurements on multiple samples retained by surface tension The invention is an installment for making multi-channel spectroscopic measurements on a plurality of nanodrop samples held by surface tension between opposing optical fibers wherein a single fiber is scanned across a linear spaced array of receiving, detecting fibe... | 01/18/2011 |
| 7858934 | Quadrupole FAIMS apparatus A combined rf-only/FAIMS apparatus is disclosed for use in mass spectrometry and other applications. The disclosed apparatus includes a plurality of curved electrodes arranged around a central ion transmission channel. FAIMS functionality is removed electronically w... | 12/28/2010 |
| 7858929 | Ion energy spread reduction for mass spectrometer A method for reducing the energy spread of ions over a specific and limited mass to charge ratio range is disclosed, along with an ion deceleration arrangement for implementing such a method. An electric field, having an electric field strength E is generated by a d... | 12/28/2010 |
| 7851745 | Flat plate FAIMS with lateral ion focusing A high field asymmetric waveform ion mobility spectrometer (FAIMS) includes at least two focusing electrodes that are separated one from the other by a gap, which decreases in width along a direction of ion flow. Within the gap is disposed an electrode assembly incl... | 12/14/2010 |
| 7829850 | Branched radio frequency multipole Systems and methods of the invention include a branched radio frequency multipole configured to act, for example, as an ion guide. The branched radio frequency multipole comprises multiple ion channels through which ions can be alternatively directed. The branched r... | 11/09/2010 |
| 7829842 | Mass spectrometer arrangement with fragmentation cell and ion selection device A method of mass spectrometry having the steps of, in a first cycle: storing sample ions in a first ion storage device; ejecting the stored ions out of the first ion storage device into a separate ion selection device; selecting a subset of the ions in the ion selec... | 11/09/2010 |
| 7821634 | Laser-triggered plasma apparatus for atomic emission spectroscopy Multiple energy sources, such as a laser and electrical current, are employed, in close coordination, spatially and temporally, to clean a sample, vaporize its material and excite vapor atoms for the purpose of atomic emission spectroscopy. These methods permit bett... | 10/26/2010 |
