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| Number | Title | Issue Date |
| 8110720 | Transgenic mice expressing humanized VEGF The present invention generally relates to humanized VEGF and non-human transgenic animals expressing it. The transgenic animals are also useful to study VEGF-related therapies. ... | 02/07/2012 |
| 8084200 | Compositions and methods for the diagnosis and treatment of tumor The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same. ... | 12/27/2011 |
| 7994286 | Neuropilin antagonists Novel anti-NRP1 antibodies and variants thereof having unique structural and functional characteristics are disclosed. Also provided are uses of the antibodies in research, diagnostic and therapeutic applications. ... | 08/09/2011 |
| 7803377 | Anti-DLL4 antibodies and methods using same The invention provides anti-DLL4 antibodies, and compositions comprising and methods of using these antibodies. ... | 09/28/2010 |
| 7482005 | Methods of treating diseases with anti-VEGF antibodies The present invention provides monoclonal antibodies, and portions thereof, which are capable of specifically binding to human vascular endothelial cell growth factor (hVEGF) or hVEGF-related protein. The invention also provides hybridoma cell lines that produce suc... | 01/27/2009 |
| 7365166 | Anti-VEGF antibodies Humanized and variant anti-VEGF antibodies and various uses therefor are disclosed. The anti-VEGF antibodies have strong binding affinities for VEGF; inhibit VEGF-induced proliferation of endothelial cells in vitro; and inhibit tumor growth in vivo. ... | 04/29/2008 |
| 6815581 | Plants which synthesize a modified starch, process for the production thereof and modified starch Nucleic acid molecules are described encoding a starch granule-bound protein as well as methods and recombinant DNA molecules for the production of transgenic plant cells and plants synthesizing a modified starch with modified viscosity properties and a modified pho... | 11/09/2004 |
| 6762346 | Nucleic acid molecules coding for debranching enzymes from maize Nucleic acid molecules are described, which encode debranching enzymes from maize, as well as transgenic plant cells and plants in which an amylopectin with modified properties is synthesized due to the expression of a debranching enzyme from maize or ... | 07/13/2004 |
| 6734339 | Nucleic acid molecules encoding enzymes from wheat which are involved in starch synthesis The present invention relates to nucleic acid molecules encoding enzymes which are involved in the starch synthesis in plants. These enzymes are starch synthases from wheat. The invention further relates to vectors and host cells containing said nucleic acid ... | 05/11/2004 |
| 6716612 | DNA molecules coding for debranching enzymes derived from plants The invention describes DNA molecules which code for plant proteins having the biological activity of a debranching enzyme. Furthermore described are transgenic plant cells and plants having reduced or increased debranching enzyme activity, as well as modified starc... | 04/06/2004 |
| 6670525 | Nucleic acid molecules coding for debranching enzymes from potato Nucleic acid molecules are described, which encode debranching enzymes from potato, as well as transgenic plant cells and plants in which an amylopectin with modified properties is synthesized due to the expression of a debranching enzyme from potato or d... | 12/30/2003 |
| 6635804 | Nucleic acid molecules encoding soluble starch synthases from maize Nucleic acid molecules are described encoding enzymes involved in the starch synthesis in plants. These enzymes are a novel isotype of soluble starch synthases from maize. Furthermore, the invention relates to vectors containing such nucleic acid molecule... | 10/21/2003 |
| 6635454 | DNA molecules coding for debranching enzymes derived from plants The invention describes DNA molecules which code for plant proteins having the biological activity of a debranching enzyme. Furthermore described are transgenic plant cells and plants having reduced or increased debranching enzyme activity, as well as mod... | 10/21/2003 |
| 6617495 | Nucleic acid molecules from plants coding enzymes which participate in the starch synthesis Nucleic acid molecules encoding enzymes which participate in the starch synthesis in plants are described. These enzymes are a novel isotype of starch synthase. Furthermore, the invention relates to vectors and hose cells which were transformed with the d... | 09/09/2003 |
| 6610843 | Modified starch from plants, plants synthesizing the same, as well as process for their production The present invention describes transgenic plant cells and plants which due to a reduced activity of a disproportionating enzyme (D enzyme) synthesize a modified starch. Furthermore, the starch synthesized in these plant cells and plants is described.... | 08/26/2003 |
