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| Number | Title | Issue Date |
| 7910312 | Use of acid scavengers for the synthesis of standard length and long-mer polymer arrays Protective groups which may be cleaved with an activatable deprotecting reagents are employed to achieve a highly sensitive, high resolution, combinatorial synthesis of pattern arrays of diverse polymers. In preferred embodiments of the instant invention, the activa... | 03/22/2011 |
| 7863344 | Photoacid generators for the synthesis of oligo-DNA in a polymer matrix Compounds represented by the following structural formulas can be used as photoacid generators: Such compounds are useful, for example, in fabricating arrays of polymers. ... | 01/04/2011 |
| 7862996 | Use of acid scavengers for the synthesis of standard length and long-mer nucleic acid arrays Protective groups which may be cleaved with an activatable deprotecting reagent are employed to achieve a highly sensitive, high resolution, combinatorial synthesis of pattern arrays of diverse polymers. In preferred embodiments of the instant invention, the activat... | 01/04/2011 |
| 7818281 | Computer software for visualizing recombination events in a group of individuals from recombination breakpoints and assignments in high density SNP genotyping data by generating a color-coded view for each individual chromosome and a whole genome view for the group A computer system for visualizing recombination events in a group of individuals is provided. According to one aspect of the invention, high-density SNP genotype data is obtained from related individuals in a family. A pedigree is created, haplotypes are reconstruct... | 10/19/2010 |
| 7803934 | Parallel preparation of high fidelity probes in an array format The present invention provides massively parallel oligonucleotide synthesis and purification for applications that utilize large collections of defined high-fidelity oligonucleotides (e.g., from about 101 to about 105 different sequences, gener... | 09/28/2010 |
| 7803609 | System, method, and product for generating patterned illumination An embodiment of a method for generating an interference pattern at a probe array is described that comprises directing light at a first waveguide and second waveguide, wherein the first and second waveguides are positioned adjacent to each other and the output from... | 09/28/2010 |
| 7790389 | Antireflective coatings for high-resolution photolithographic synthesis of DNA arrays The present invention provides an array of polymers and methods of forming arrays of polymers by providing a substrate having a first layer including one or more dielectric coatings on a solid support and a second layer including a plurality of polymers disposed on ... | 09/07/2010 |
| 7452673 | Photoacid generators for the synthesis of oligo-DNA in a polymer matrix Compounds represented by the following structural formulas can be used as photoacid generators: Such compounds are useful, for example, in fabricating arrays of polymers. ... | 11/18/2008 |
| 7364895 | Bioarray chip reaction apparatus and its manufacture A body 300 having a cavity 310 for mounting a substrate 120 fabricated with probe sequences at known locations according to the methods disclosed in U.S. Pat. No. 5,143,854 and PCT WO 92/10092 or others, is provided. The cavity includes inlets | 04/29/2008 |
