"The Americans have need of the telephone, but we do not. We have plenty of messenger boys."
Sir William Preece, chief engineer, British Post Office ; 1878
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| Number | Title | Issue Date |
| 7940550 | Systems and methods for reducing memory array leakage in high capacity memories by selective biasing A source-biasing mechanism for leakage reduction in SRAM in which SRAM cells are arranged into a plurality of sectors. In standby mode, the SRAM cells in a sector in the plurality of sectors are deselected and a source-biasing potential is provided to the SRAM cells... | 05/10/2011 |
| 7939677 | Oligomeric compounds comprising 4′-thionucleosides for use in gene modulation The present invention provides modified oligomeric compounds and compositions of oligomeric compounds for use in the RNA interference pathway of gene modulation. The modified oligomeric compounds include siRNA and asRNA having at least one affinity modification.... | 05/10/2011 |
| 7939551 | Combination therapeutic compositions The present invention provides pharmaceutical compositions and methods for the treatment of diabetes mellitus using combination therapy. The compositions relate to a compound of Formula I and an antidiabetic agent such as sulfonylureas, biguanides, glitazones, α-gl... | 05/10/2011 |
| 7939468 | Methods of identifying compounds that target tRNA splicing endonuclease and uses of said compounds as anti-proliferative agents The present invention relates to a method for screening and identifying compounds that modulate the activity tRNA splicing endonuclease. In particular, the invention provides assays for the identification of compounds that inhibit animalia tRNA splicing endonuclease... | 05/10/2011 |
| 7939271 | Methods and compositions for identifying prostate cancer or a humoral immune response against prostate cancer The present invention relates to prostate cancer markers, compositions comprising such markers, immunoglobulins specific for such markers, and methods of using such markers and/or immunoglobulins to assess an immune response against prostate cancer. An immune respon... | 05/10/2011 |
| 7938729 | Frictional clutch with O-ring A frictional clutch for a hand-held device for transferring a film from a backing tape onto a substrate comprises a first main member having a cylindrical element coaxially protruding into a circular center opening of a second main member. The first and secon... | 05/10/2011 |
| 7937837 | Razor head having two shaving heads A razor that includes a handle having an axis, a first shaver head having one or more blades, mounted at a front end of the handle and a second shaver head mounted on a support mounted at a back end of the handle and pivotable with respect to the support between an ... | 05/10/2011 |
| 7935785 | Selective substrates for matrix metalloproteinases The invention provides isolated MMP-2, MMP-9 and MT1-MMP selective substrate polypeptides or functional peptidomimetics. The selective substrate polypeptides contain the following sequences: MMP-2 selective substrate polypeptides contain SEQ ID NOS:1-27, MMP-9 selec... | 05/03/2011 |
| 7935156 | Jet fuel compositions and methods of making and using same Provided herein are, among other things, jet fuel compositions and methods of making and using the same. In some embodiments, the fuel compositions comprise at least a fuel component readily and efficiently produced, at least in part, from a microorganism. In certai... | 05/03/2011 |
| 7934883 | Writing instrument comprising a cartridge support A writing instrument that includes a barrel extending along a longitudinal axis, a cartridge housed inside the barrel and having a front end connected to a writing point and a rear end, and a cartridge support connected to the barrel and against which the rear end o... | 05/03/2011 |
| 7934356 | Machine for filling bag with medicine To quickly fill a bag with medicine containers without damaging the containers, a machine for filling a bag with medicine containers includes: a bag positioning member (4) for positioning and opening a bag (13); a first moving member (37) that r... | 05/03/2011 |
| 7934320 | Razor handle having an arcuate profile A razor handle having a front end, a back end opposite the front end, an upper surface, a lower surface opposite the upper surface, and a length in a longitudinal direction defined between the front and back ends. The razor handle includes a head portion and a body ... | 05/03/2011 |
| D637211 | Compressor | 05/03/2011 |
| 7934015 | System and method for addressing a mobile device in an IP-based wireless network A system and method for addressing a mobile device in an IP-based wireless network is provided. Push service providers prepare data for transmission to the mobile device using a first IP address. The addressed data is then transmitted to a push proxy. The push proxy... | 04/26/2011 |
| 7933683 | Partition plate usable for V-measure in medicine holding machine Embodiments of the invention provide a partition plate capable of efficiently cleaning a medicine remaining in a V-measure. The partition plate comprises: a slide member (8) which is installed so as to be capable of reciprocating along side plates and has a g... | 04/26/2011 |
| 7932240 | Phosphadiazine HCV polymerase inhibitors IV Provided herein are phosphadiazine polymerase inhibitor, for example, of any of Formulas IV, IV′, I″, II″, or IVa, pharmaceutical compositions comprising the compounds, and processes of preparation thereof. Also provided are methods of their use for the treatm... | 04/26/2011 |
| 7932026 | EGFR mutations The present invention relates to mutations in Epidermal Growth Factor Receptor (EGFR) and methods of detecting such mutations as well as prognostic methods method for identifying a tumors that are susceptible to anticancer therapy such as chemotherapy and/or kinase ... | 04/26/2011 |
| 7931637 | Hemostatic compositions and uses therefor The present invention relates generally to the field of hemostasis, including methods, compositions, and devices that can be employed to achieve hemostasis at an increased rate. More specifically the present invention relates to hemostatic compositions that achieve ... | 04/26/2011 |
| D636792 | Compressor | 04/26/2011 |
| 7930518 | Method for manipulating data in a group of processing elements to perform a reflection of the data A method for generating a reflection of data in a plurality of processing elements comprises shifting the data along, for example, each row in the array until each processing element in the row has received all the data held by every other processing element in that... | 04/19/2011 |
| 7930200 | Computer-implemented systems and methods for cross-price analysis Computer-implemented systems and methods for determining demand of products. A system and method can be configured to determine a price with respect to a first attribute of a first product. This determination is based upon the price data of the products which compet... | 04/19/2011 |
| 7928338 | Plasma spraying device and method A device and a method for plasma spraying are disclosed. The device comprises, a cathode, an anode, a plasma channel formed by the anode and intermediate electrodes, and one or more flowable material injectors. The plasma channel has a throttling portion that divide... | 04/19/2011 |
| 7928280 | Treatment of leg ulcers using placenta derived collagen biofabric The present invention provides a method of treating a leg ulcer comprising contacting the leg ulcer with a collagen biofabric. The leg ulcer may be a venous, arterial, diabetic or decubitus (pressure) ulcer. The invention further provides kits comprising one or more... | 04/19/2011 |
| 7927832 | Nucleic acid encoding proteins involved in protein degradation, products and methods related thereto In accordance with the present invention, there are provided novel Siah-Mediated-Degradation-Proteins (SMDPs) and/or SCF-Complex Proteins (SCPs). Nucleic acid sequences encoding such proteins and assays employing same are also disclosed. The invention SMDPs and/or S... | 04/19/2011 |
| 7927791 | Methods for identifying small molecules that modulate premature translation termination and nonsense mediated mRNA decay The present invention relates to a method for screening and identifying compounds that modulate premature translation termination and/or nonsense-mediated messenger ribonucleic acid (“mRNA”) by interacting with a preselected target ribonucleic acid (“RNA”). ... | 04/19/2011 |
| 7927592 | Method of inhibiting complement activation The invention relates to C2a inhibitors, which bind to C2a and block the functional activity of C2a in complement activation. The inhibitors include antibody molecules, as well as homologues, analogues and modified or derived forms thereof, including immunoglobulin ... | 04/19/2011 |
| 7926971 | Battery pack assemblies and portable lighting devices employing same A portable electronic device, such as a flashlight, with a battery pack assembly is provided. The battery pack assembly has a cylindrically shaped housing with a base and a cover that form a chamber to hold a battery pack. A printed circuit board is installed in the... | 04/19/2011 |
| D636409 | Compressor | 04/19/2011 |
| 7923564 | Synthesis of N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N′-(4-(2-methylpropyloxy) phenylmethyl)carbamide and its tartrate salt and crystalline forms Disclosed herein are methods for synthesizing N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N′-(4-(2-methylpropyloxy)-phenylmethyl)carbamide. Also disclosed herein is the hemi-tartrate salt of N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N′-(4-(2-methylpropylox... | 04/12/2011 |
| 7921359 | Computer-implemented system and method for tagged and rectangular data processing A computer-implemented system and method for tagged data and rectangular data conversions. The system and method receive tagged input data that is in a non-rectangular format and uses a hierarchical arrangement of tags to indicate data relationships. Data directives... | 04/05/2011 |
| 7920074 | Apparatus and method for an accelerated thumbwheel on a communications device An accelerated roller apparatus on a handheld electronic communications device that handles urgency conditions. The device includes a manipulable mechanism that is capable of generating a manipulation-related signal. Changes in the signal occur whenever motion is im... | 04/05/2011 |
| 7919605 | Nucleic acids, compositions and methods for the excision of target nucleic acids Nucleic acids, compositions, and methods that allow for the excision of one or more loci from the genome of a host cell are provided herein. In particular, provided herein is an excisable nucleic acid construct comprising, in a 5′ to 3′ orientation: a first tand... | 04/05/2011 |
| 7919472 | Enhanced antisense oligonucleotides Described herein are gap-widened antisense oligonucleotides having improved therapeutic index as compared to 5-10-5 MOE gapmer antisense oligonucleotides of the same sequence. Also described are methods of reducing a target RNA in an animal using the gap-widened ant... | 04/05/2011 |
| 7919317 | Methods of differentiating and protecting cells by modulating the P38/MEF2 pathway The present invention provides a method of differentiating progenitor cells to produce a population containing protected neuronal cells. A method of the invention includes the steps of contacting the progenitor cells with a differentiating agent; and introducing int... | 04/05/2011 |
| 7919098 | ErbB-3 based methods and compositions for treating neoplasms The present invention relates to compositions and methods for treating neoplasms in mammals, particularly humans. More particularly, the present invention provides for methods for preventing, treating or delaying neoplasm in a mammal using an ErbB-3 protein, a nucle... | 04/05/2011 |
| 7918968 | Apparatus for cleaning paper machine press fabrics on-the-run An apparatus is described for cleaning papermaking felt by applying a low concentration of a cleaning solution through the oscillating needle nozzles. The detergent is applied intermittently while paper is being manufactured. Each cleaning period lasts for at least ... | 04/05/2011 |
| 7917126 | System and method of exchanging identification information for mobile stations A system is provided for allowing mobile stations to exchange identification information using a predetermined communication path for the purpose of obtaining identification information to use in establishing a different communication path for communicating. ... | 03/29/2011 |
| 7915231 | Antisense modulation of C-reactive protein expression Antisense compounds, compositions and methods are provided for modulating the expression of C-reactive protein. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding C-reactive protein. Methods of ... | 03/29/2011 |
| 7914988 | Gene expression profiles to predict relapse of prostate cancer The present invention provides a method for preparing a reference model for cancer relapse prediction that provides higher resolution grading than Gleason score alone. The method encompasses obtaining from different individuals a plurality of prostate carcinoma tiss... | 03/29/2011 |
| 7914779 | Tissue matrices comprising placental stem cells, and methods of making the same A method of manufacturing a tissue matrix for implantation into a patient is disclosed. The method sets forth collecting embryonic stem cells from a placenta which has been treated to remove residual cord blood and seeding the collected stem cells onto or into a tis... | 03/29/2011 |