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| Number | Title | Issue Date |
| 4870101 | Method of inhibiting interleukin-1 release Methods useful for inhibiting the release of interleukin-1 and for alleviating interleukin-1 mediated conditions, such as IL-1-mediated inflammation, comprising administration of an effective amount of a pharmaceutically acceptable antioxidant compound su... | 09/26/1989 |
| 4543221 | Method for making cellulose semipermeable hollow fibers Improved cellulose semipermeable hollow fibers useful in detoxifying blood during hemodialysis or hemofiltration treatments. The cellulose fibers are fine, capillary fibers that are made by melt extrusion of certain cellulose ester polyol melt spin compos... | 09/24/1985 |
| 4526890 | 3,6,7,8-Substituted-s-triazolo[4,3-b]pyridazines as bronchodilators 3,6,7,8-Substituted-s-triazolo-pyridazine compounds such as 7,8-dimethyl-6-morpholino-3-methyl-s-triazolo[4,3-b]pyridazine or 7,8-dimethyl-6-(1-pyrrolidinyl)-3-(isopropyl)-s-triazolo-[4,3-b]pyridazine are prepared by the reaction of a carboxylic acid with... | 07/02/1985 |
| 4271155 | Water soluble hydrazones of 3-formylrifamycin SV, antibacterial compositions thereof and method of use thereof The invention relates to new water soluble 3-formylrifamycin SV hydrazones wherein the hydrazone moiety contains a phosphonoxy lower alkyl radical which imparts water solubility. The compositions containing said rifamycin derivatives are also an object of... | 06/02/1981 |
| 4072565 | Production of viruses in tissue culture without use of serum Growth of cells in tissue culture and virus vaccine production in tissue culture in the absence of serum are disclosed. The cells in tissue culture are grown initially in a chemically defined medium containing protamine zinc insulin, and the protamine zin... | 02/07/1978 |
| 4049814 | Substituted phenoxyalkyl quaternary ammonium compounds as antiarrhythemic agents Quaternary ammonium compounds such as [2-(4-amino-2,6-dibromophenoxy)ethyl]dimethyl (allyl) ammonium bromide are prepared by the reaction of a tertiary amine such as 3,5-dibromo-ଲ-dimethylamino-p-phenetidine with a substituted organic compound ... | 09/20/1977 |
| 4042692 | Substituted phenoxyalkyl quaternary ammonium compounds as antiarrhythemic agents Quaternary ammonium compounds such as [2-(4-amino-2,6-dibromophenoxy)ethyl]dimethyl (allyl) ammonium bromide are prepared by the reaction of a tertiary amine such as 3,5-dibromo-ଲ-dimethylamino-p-phenetidine with a substituted organic compound ... | 08/16/1977 |
| 4042709 | Substituted phenoxyalkyl quaternary ammonium compounds as antiarrhythmic agents Quaternary ammonium compounds such as [2-(4-amino-2,6-dibromophenoxy)ethyl]dimethyl (allyl) ammonium bromide are prepared by the reaction of a tertiary amine such as 3,5-dibromo-ଲ-dimethylamino-p-phenetidine with a substituted organic compound ... | 08/16/1977 |
| 4042712 | Substituted phenoxyalkyl quaternary ammonium compounds as antiarrhythemic agents Quaternary ammonium compounds such as [2-(4-amino-2,6-dibromophenoxy)ethyl]dimethyl (allyl) ammonium bromide are prepared by the reaction of a tertiary amine such as 3,5-dibromo-8-dimethylamino-p-phenetidine with a substituted organic compound such a... | 08/16/1977 |
| 4029703 | N,N'-disubstituted halophenylacetamidines N,N'-Disubstituted halophenylacetamidine compounds such as N,N'-dimethyl-3,4-dichlorophenyl-acetamidine, and their pharmaceutically-acceptable salts are prepared by the reaction of a substituted phenylacetonitrile with an alkylamine and alkylammonium salt... | 06/14/1977 |
| 4024021 | Determination of glutamate and glutamic transaminases Glutamate and glutamic transaminases are determined by mixing a substrate-reagent composition that is essentially free of ammonia or ammonium ions with a specimen to be analyzed, incubating the resulting mixture for less than about 15 minutes, terminating... | 05/17/1977 |
| 4016162 | 6-Morpholino-3-substituted phenyl-S-triazolo[4,3-b]pyridazines 6-Morpholino-3-substituted phenyl triazolopyridazine compounds such as 8-methyl-6-morpholino-3-phenyl-s-triazolo[4,3-b]pyridazine or 8-methyl-6-morpholino-3-(3,4,5-trimethoxyphenyl)-s-triazolo[4,3-b]pyridazi ne are prepared by the reaction of the correspon... | 04/05/1977 |
| 4001089 | Method for determination of triglycerides and glycerol A novel reagent and method for colorimetrically determining the concentration of triglycerides in biological fluids, and for rapid determination of glycerol are described. Triglycerides are hydrolyzed in methanolic base to glycerol, and glycerol content i... | 01/04/1977 |
| 3991210 | Acetamidine urinary antiseptics The disclosure relates to a method useful for combating microorganisms associated with infections of the urinary tract in mammals by means of administering to mammals an amount of a substituted acetamidine compound such as 2-(4-bromophenyl) acetamidine or... | 11/09/1976 |
| 3989613 | Continuous balanced flow fixed boundary electrophoresis A continuous balanced flow electrophoresis apparatus utilizes a fixed, colloid-permeable boundary membrane across which net liquid flow is minimized. The apparatus is employed in electrophoretic separation of colloids such as blood plasma proteins in whic... | 11/02/1976 |
| 3988474 | N,N'-dialkyl-halobenzamidines as antidepressants A method useful for alleviating central nervous system depression comprises administration to animals of an effective amount of an N,N'-dialkyl-halobenzamidine. Compositions useful in practicing the method are also disclosed.... | 10/26/1976 |
| 3983250 | Halophenyl acetamidines as anxiolytic antidepressants A method useful for alleviating central nervous system depression and anxiety symptoms comprises administration to animals of an effective amount of an N,N'-dialkyl-2-halophenyl acetamidine. Compositions useful in practicing the method are also disclosed.... | 09/28/1976 |
| 3972931 | N,N'-Disubstituted benzamidines N,N'-Disubstituted benzamidine compounds such as N,N'-dimethyl-3,4-dichlorobenzamidine, and their pharmaceutically-acceptable salts are prepared by the reaction of a substituted phenylacetonitrile with an alkylamine and alkylammonium salt or alternat... | 08/03/1976 |
| 3951821 | Disintegrating agent for tablets Disintegration of tablets is improved by the incorporation therein of a plurality of small tubules. The tubules can be prepared by subdivision of hollow fibers such as cellulose or cellulose acetate hollow fibers having inside diameters on the order of 50... | 04/20/1976 |
| 3950538 | Anti-inflammatory methods utilizing certain thioureas A method of alleviating symptoms of inflammation in a mammal suffering from an inflammatory condition which comprises the administration to such mammal of a pharmaceutically effective amount of a 1-aryl-3-(2-hydroxyethyl)thiourea derivative.... | 04/13/1976 |
| 3938954 | Determination of calcium An improved reagent system for determining calcium by the orthocresolphthalein complexone color reaction. The reagent utilizes an alkaline buffer containing an aminoloweralkanol providing a pH of about 10.2 - 10.5. A method for using the reagent is also d... | 02/17/1976 |
| 3934020 | Halophenyl acetamidines as anxiolytic antidepressants A method useful for alleviating central nervous system depression and anxiety symptoms comprises administration to animals of an effective amount of an N,N'-dialkyl-2-halophenyl acetamidine. Compositions useful in practicing the method are also disclosed.... | 01/20/1976 |
| 3933912 | Substituted phenylthioamidines Substituted phenylthioamidine compounds such as 2-(4-chlorophenylthio)acetamidine; 2-(4-chlorophenylthio)-acetamidoxime; and their pharmaceutically acceptable salts are prepared by the reaction of a substituted phenylthioacetonitrile with hydroxylamine hy... | 01/20/1976 |
| 3932664 | Substituted phenoxyalkyl quaternary ammonium compounds as antiarrhythemic agents Quaternary ammonium compounds such as [2-(4-amino-2,6-dibromophenoxy)ethyl[dimethyl (allyl) ammonium bromide are prepared by the reaction of a tertiary amine such as 3,5-dibromo-ଲ-dimethylamino-p-phenetidine with a substituted organic compound ... | 01/13/1976 |