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Attorney: Johnson; Lester E.


Number of patents: 68
Last date: January 19, 1988

1    
NumberTitleIssue Date
4720385Protein compositions substantially free from infectious agents
Compositions containing therapeutically or immunologically active proteins are rendered substantially free from infectious agents such as viable viruses and bacteria without substantial loss of therapeutic or immunologic activity by mixing the protein com...
01/19/1988
4713246Etoposide oral dosage form
A liquid dosage form suitable for oral administration of etoposide which is sufficiently concentrated to be administered in capsule form and which provides improved absorption of the drug relative to prior oral formulations....
12/15/1987
4684723Method of separating proteins from aqueous solutions
There is disclosed an improved method for separating and recovering proteins, particularly therapeutically active proteins, from an aqueous system also containing a component having the ability to create two liquid phases by use of salt partitioning techn...
08/04/1987
4656254Method of preparing alpha-1-proteinase inhibitor and antithrombin III
There is disclosed an improved method for separating one of alpha-1-proteinase inhibitor (also known as alpha-1 antitrypsin) and antithrombin-III from an aqueous solution of plasma proteins containing the same, such as from Cohn Fraction IV-1, Cohn Fracti...
04/07/1987
4649048Novel bile sequestrant resin
Particular quaternized vinylimidazole-ethylene glycol dimethacrylate copolymers are useful to sequester non-absorbed bile acids in the intestinal tract to form a complex which is excreted in the feces....
03/10/1987
4604430Novel bile sequestrant resin
Particular quaternized vinylimidazole-ethylene glycol dimethacrylate copolymers are useful to sequester non-absorbed bile acids in the intestinal tract to form a complex which is excreted in the feces....
08/05/1986
4600578Method of inhibiting diarrhea
Oral administration of particular quaternized vinylimidazole-ethylene glycol dimethacrylate copolymers inhibits diarrhea....
07/15/1986
4587121High titer Pseudomonas immune serum globulin
Normal plasma from donors who have not been vaccinated with a Pseudomonas vaccine or had a Pseudomonas infection can be screened for higher than normal titers of naturally occurring antibody to four of seven Fisher Immunotypes for Pseudomonas. Those plasm...
05/06/1986
4543210Process for producing a high purity antihemophilic factor concentrate
There is disclosed an improved process for producing high purity antihemophilic factor concentrate from an antihemophilic factor-containing dispersion or solution isolated from blood plasma or a blood plasma fraction, wherein the improvement is in carryin...
09/24/1985
4534972Protein compositions substantially free from infectious agents
Compositions containing therapeutically or immunologically active proteins are rendered substantially free from infectious agents such as viable viruses and bacteria without substantial loss of therapeutic or immunologic activity by mixing the protein com...
08/13/1985
4499073Intravenously injectable immune serum globulin
A composition is disclosed which comprises a solution in a pharmaceutically acceptable carrier of an immune serum globulin, said solution having an ionic strength and a pH to maintain the monomer content and the actual and latent anticomplement activity o...
02/12/1985
4496689Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer
There is disclosed a process for producing a covalently attached alpha-1-proteinase inhibitor - water soluble polymer complex useful for pulmonary emphysema therapy, a covalently attached alpha-1-proteinase inhibitor - water soluble polymer complex produc...
01/29/1985
4477432Oral immune globulin
There is disclosed an oral pharmaceutical composition for therapeutic use comprising a therapeutically effective amount of orally administerable immune globulin in a pharmaceutically acceptable carrier....
10/16/1984
4473553Process for producing a lipoprotein-poor concentrate of coagulation factors VII and VIIa
There is disclosed a process for producing coagulation factors VII and VIIa in relatively high purity by contacting an aqueous preparation containing factors VII and VIIa with a lipoprotein binding adsorbent and separating the coagulation factors and othe...
09/25/1984
4470969Process for producing a concentrate of coagulation factors VII and VIIa
There is disclosed a process for producing coagulation factors VII and VIIa in relatively high purity by contacting an aqueous preparation containing factors VII and VIIa with a protein precipitant and separating the coagulation factors and other proteins...
09/11/1984
4455300Fibronectin compositions
Novel compositions containing fibronectin and methods of isolating these compositions and fibronectin itself from blood plasma are disclosed....
06/19/1984
4452893Cell growth medium supplement
Fraction IV, a discard fraction of the Cohn fractionation scheme, may be used as a supplement in cell growth media if the Fraction IV is rendered substantially free of components within the molecular weight range 2.5×105 -1.0×1010,...
06/05/1984
4446126Antithrombin-heparin complex and method for its production
A complex of antithrombin and high activity heparin is provided for use as a potent anticoagulant for humans. The complex is prepared by reversibly immobilizing it on a lectin-containing, water-insoluble gel matrix and then removing it from the matrix....
05/01/1984
4440679Pasteurized therapeutically active protein compositions
Compositions containing thermally sensitive, therapeutically active proteins are pasteurized without substantial loss of therapeutic activity by mixing the protein composition with a pasteurization-stabilizing amount of a polyol prior to pasteurization. P...
04/03/1984
4439358Method of preparing alpha-1-proteinase inhibitor
A method is disclosed for separating alpha-1-proteinase inhibitor from a blood plasma fraction particularly from the Cohn fractionation scheme. An aqueous solution of the blood plasma fraction is held at a pH of about 6.5-8.5, and a temperature of about 2...
03/27/1984
4421902Alkyl, poly(oxyethylene) poly(carbonyloxyethylene) acrylate emulsion copolymers for thickening purposes
There are disclosed polymerizable alkyl poly(oxyethylene) poly(carbonyloxyethylene)acrylates and copolymers thereof, especially stable, aqueous dispersions of water-insoluble emulsion copolymers of (1) about 10-70% by weight of (meth)acrylic, (2) about 0....
12/20/1983
4401461Herbicidal 4-nitro-diphenyl ethers
This invention relates to novel herbicidal compounds of the formula ##STR1## wherein X is a (C1 -C6)alkoxy group, a (C1 -C4)alkyl group, an alkoxyalkoxy group, wherein each alkyl moiety has 1 to 4 carbon at...
08/30/1983
4398942Herbicidally-active phenylacetonitriles
There is disclosed a method for selectively regulating weed plant growth in transplanted rice fields under aquatic conditions which comprises applying to said weed plants an effective amount of a compound of the formula: ##STR1## wherein: X is select...
08/16/1983
4387190Autoxidizable compositions containing low molecular weight polymers of dicyclopentenyl methacrylate or dicyclopentenyloxyalkyl methacrylate
An improved autoxidizable coating and/or impregnating composition consisting essentially of: (1) from about 35% to about 80% by weight, based on the total weight of components (1), (2), and (3), of a film-forming component selected from the group consisti...
06/07/1983
4376844Hydrocurable ambient curing polyepoxide coating and adhesive compositions and method of using them
Resin-forming polyepoxides are mixed with polyoxazolidinyl compounds or polymers containing pendant oxazolidinyl groups in which the carbon atom in the 2-position of the heterocyclic ring is substituted with saturated hydrocarbon groups, such as dialkyl, ...
03/15/1983
4373008Ambient hydrocurable coating compositions
The present invention is concerned with, as a hydrocurable composition, a mixture of an oxazolidine-functional polymer and a compound of a monomeric or polymeric character having a plurality of acryloxy groups. The first-mentioned polymer contains a plura...
02/08/1983
4360540Radiation curable compositions containing cyanoalkoxyalkyl and cyanothiaalkylalkyl acrylates
There are disclosed radiation curable compositions containing (a) about 5-95% by weight of at least one cyanoalkoxyalkyl or cyanothiaalkylalkyl acrylate, (b) about 1-90% by weight of a photopolymerizable acrylated polymer or oil, and (c) from 0 to about 5...
11/23/1982
4351875Heteropolymer acrylic latices and textiles treated therewith
Tear resistance and flexibility of resin-treated textiles are improved while retaining good low temperature properties by using as the resin an acrylic emulsion polymer wherein the latex particles have a core-shell structure. The monomers forming the core...
09/28/1982
4345934Method of producing hybrid cereal grain seeds by application of 1-aryl-1,4-dihydro-4-oxo(thio)-pyridazines
Compounds of the formula ##STR1## wherein R1 is aryl or substituted aryl, R2 is alkyl, or aryl, R3 is hydrogen, alkyl, aralkyl, or halogen, or R2 and R3 taken together are --(CH2)n --...
08/24/1982
4336023Formaldehyde-free durable press finish fabrics
There is disclosed a process for imparting to cellulose or cellulose-containing textile materials durable press properties by treating cellulose or cellulose-containing textile materials by applying to the textile materials a treating composition of (a) a...
06/22/1982
4333963Radiation curable compositions containing ଲ-cyanoethoxyalkyl acrylates
There are disclosed radiation curable compositions containing (a) about 5-95% by weight of at least one ଲ-cyanoethoxyalkyl acrylate, (b) about 1-90% by weight of a photopolymerizable acrylated polymer or oil, and (c) from 0 to about 5% by weight of ...
06/08/1982
4331793Hydrocurable ambient curing polyepoxide coating and adhesive compositions and method of using them
Resin-forming polyepoxides are mixed with polyoxazolidinyl compounds or polymers containing pendant oxazolidinyl groups in which the carbon atom in the 2-position of the heterocyclic ring is substituted with saturated hydrocarbon groups, such as dialkyl, ...
05/25/1982
4314802Process for producing leather
This invention relates to an improved process for producing a tanned heavy leather, sometimes called full thickness leather, suitable for use for shoe soles, belts and straps, bags and cases, and saddles, bridles, and harness, wherein, under carefully con...
02/09/1982
4311624Autoxidizable compositions
Disclosed is an improved autoxidizable coating and/or impregnating composition containing (1) a reactive non-volatile diluent monomer system of a mixture of dicyclopentenyloxyalkyl esters of polymerizable ethylenically unsaturated carboxylic acids and met...
01/19/1982
4308356Hydrocurable ambient curing polyepoxide coating and adhesive compositions and method of using same
Resin-forming polyepoxides are mixed with polyoxazolidinyl compounds or polymers containing pendant oxazolidinyl groups in which the carbon atom in the 2-position of the heterocyclic ring is substituted with saturated hydrocarbon groups, such as dialkyl, ...
12/29/1981
4299867Ambient hydrocurable coating and adhesives compositions
The present invention is concerned with, as a hydrocurable composition, a mixture of an oxazolidine-functional polymer and a compound of a monomeric or polymeric character having a plurality of acryloxy groups. The first-mentioned polymer contains a plura...
11/10/1981
4299761Polymer concrete compositions, methods of application thereof, and polymerized products thereof
Polymer concrete compositions of essentially anhydrous character comprising an inert, inorganic particulate or granular material, such as sand, crushed stone or rock, and mixtures thereof, mixed with a monomeric dicyclopentenyloxylalkyl acrylate or methac...
11/10/1981
4289823Calenderable acrylic polymers and textiles treated therewith
There is disclosed a calenderable, soft, three-stage acrylic heteropolymer having a calculated Tg of about (-) 40° to (=) 20° C. which is suitable for producing films and sheets useful to coat textile materials and other substrates to form co...
09/15/1981
4277384Heteropolymer acrylic latices and textiles treated therewith
Tear resistance and flexibility of resin-treated textiles are improved while retaining good low temperature properties by using as the resin an acrylic emulsion polymer wherein the latex particles have a core-shell structure. The monomers forming the core...
07/07/1981
4263372Method of coating and/or impregnating porous substrates, and products obtained thereby
This application concerns compositions comprising a mixture of an air-drying dicyclopentenyl acrylate or methacrylate binder and a granular or particulate aggregate material, which may comprise a hydraulic cement, and is adapted to be formed by casting, e...
04/21/1981
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