Did You Know...
...that after Parker Brothers executives turned down the game of Monopoly because it had "52 fundamental errors" (including taking too long to play), a copy of the game wound up in the home of the company president who stayed up until 1 a.m. to finish playing it? He was so impressed by the game that the next day he wrote to inventor Charles Darrow and offered to buy it!
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| Number | Title | Issue Date |
| 6841052 | Electrochemical-sensor design An improved electrochemical sensor having a base bearing a working and counter electrode which provides a flow path for a fluid test sample. The working and counter electrodes are configured so that a major portion of the counter electrode is located downstream on t... | 01/11/2005 |
| 6752817 | Split pressure ring for lancing device and method of operation A pressure ring for a lancing device for holding open a skin puncture while collecting a blood sample includes a collar that fits onto the end of a lancing device. A skirt is provided on the collar and a flared portion depends from the skirt. At least one axial slit... | 06/22/2004 |
| 6661647 | Snap-in display frame An apparatus (26) for mounting a display screen (28) to a printed circuit board (32). The display screen (28) has four edges. The apparatus (26) includes a top member (34) opposed to a bottom member (36), and first and second snap-fit members (40). The to... | 12/09/2003 |
| 6607543 | Lancing mechanism A lancing mechanism for puncturing skin is provided. The lancing mechanism comprises a lance having a penetration end which is adapted to puncture skin. The penetration end of the lance is movable from a first position to a second position during a forwar... | 08/19/2003 |
| 6604050 | System, method and biosensor apparatus for data communications with a personal data assistant A system, method and biosensor apparatus are provided for data communications with a personal data assistant. The biosensor apparatus includes a sensor for receiving a user sample to be measured and a microcontroller for performing a predefined test seque... | 08/05/2003 |
| 6603987 | Hollow microneedle patch A test strip is provided for use in the determination of the concentration of an a chemical in blood. The test strip comprises a plurality of microneedles and a test area. Each microneedle is adapted to puncture skin and to draw blood. The test area is in... | 08/05/2003 |
| 6561989 | Thin lance and test sensor having same A lance is provided for puncturing skin and producing a sample of blood. The lance comprises a spring having a first end and a second end disposed between a needle and a base wherein the first end of spring is coupled to the base and the second end of the... | 05/13/2003 |
| 6531040 | Electrochemical-sensor design Disclosed is an electrochemical sensor for detecting the concentration of an analyte such as glucose in a fluid test sample. The sensor involves a base as flow path for the fluid test sample having a working and counter electrode on its surface. The base ... | 03/11/2003 |
| 6473190 | Optical volume sensor An optical sensor for measuring the volume of an object, the object having a top and a side. The optical sensor comprises a source of light and a light sensor adapted to measure the amount of light reflected off the side and off the top of the object, whe... | 10/29/2002 |
| 6451040 | Adjustable endcap for lancing device An adjustable endcap for a lancing device includes a basecap and a twistcap. The basecap includes a post with detents thereon. At least one finger is provided on the basecap adjacent the post. The twistcap includes at least one helical track on its outer ... | 09/17/2002 |
| 6436721 | Device and method for obtaining clinically significant analyte ratios Disclosed is a method for determining the concentration of an analyte in a sample of body fluid. The method involves contacting the body fluid sample with a test strip containing mobile, labeled specific binding partner for the analyte, through which stri... | 08/20/2002 |
| 6406858 | System for the reduction of interferences in immunoassays The present invention is an improvement to the method of determining the concentration of an analyte in body fluid using at least two immunoreactants which specifically bind with separate epitopes of the analyte one of which immunoreactant is immobilized ... | 06/18/2002 |
| 6391645 | Method and apparatus for correcting ambient temperature effect in biosensors A method and apparatus are provided for correcting ambient temperature effect in biosensors. An ambient temperature value is measured. A sample is applied to the biosensors, then a current generated in the test sample is measured. An observed analyte conc... | 05/21/2002 |
| 6364889 | Electronic lancing device It has been discovered that the use of a substantially free-standing voice coil within a lancing device in coordination and combination with a stationary magnet and electronic circuit renders a much improved lancing device. The minimal weight of the free ... | 04/02/2002 |
| 6338969 | Assay test system for regulating temperature Disclosed is a dry assay device for carrying out immunochromatographic assays. The device involves an assay strip contained in the interior of a plastic cassette along with a thermally conductive material in thermal communication with the assay strip to m... | 01/15/2002 |
| 6335204 | Fixed volume liquid transfer device and method for transferring liquids A fixed volume liquid transfer device defined by a small bore tube having an open end for collection of liquids and a plunger in the tube is disclosed. A piston is mounted around the open end and an air plug is mounted in the piston adjacent the open end.... | 01/01/2002 |
| 6316264 | Test strip for the assay of an analyte in a liquid sample An improved test strip for determining the presence or concentration of unknown or a constituent in a liquid test sample is disclosed. The test strip comprises a support strip and a test pad, wherein the test pad includes a carrier matrix incorporating a ... | 11/13/2001 |
| 6306660 | Method for improving the accuracy of the semi-quantitative determination of analyte in fluid samples Disclosed is an improved method for determining the concentration of a first analyte in a fluid test sample as a function of a second analyte also present in the sample whose concentration in the fluid sample is clinically related to that of the first ana... | 10/23/2001 |
| 6246966 | Method and apparatus for data management authentication in a clinical analyzer A method and apparatus are provided for data management authentication in a clinical analyzer. The clinical analyzer includes a sensor for receiving a user sample to be measured and a processor for performing a predefined test sequence for measuring a pre... | 06/12/2001 |
| 6239445 | Optical inspection apparatus with removable inserts An apparatus in accordance with the invention is directed to an optical inspection apparatus (10) adapted to inspect a liquid sample. The apparatus includes a tray (20) that is adapted to be physically coupled to a first liquid sample carrier (22) and a s... | 05/29/2001 |
| 6228602 | Competitive apo-peroxidase assay Disclosed is an assay for an analyte in a fluid test sample such as urine which involves combining the fluid test sample with a reagent system comprising an apo-peroxidase, a redox dye, a peroxide and a metal porphyrin which is bound to an analyte/analyte... | 05/08/2001 |
| 6210971 | Assay for the detection of creatinine Disclosed is an improved method for the detection of creatinine in a fluid test sample by contacting the test sample with cupric ions, a hydroperoxide, citrate and an oxidizable dye which gives a colored response in the presence of oxygen free radicals an... | 04/03/2001 |
| 6210978 | Method and device for the detection of analyte in a fluid test sample Disclosed is a method for the immobilization of an analyte such as deoxypyridinium (DPD) onto a solid support. The method involves binding an antigen-amino acid-deoxypyridinium complex to the support via an anti-antigen binding partner located in a captur... | 04/03/2001 |
| 6187268 | Transparent flow through membrane for dry reagent analytical devices Disclosed is a diagnostic device for the colorimetric detection of an analyte in a test fluid. The device is a dry reagent layer which is overcoated with a transparent, fluid permeable membrane. The membrane is made up of a combination of a water dispersi... | 02/13/2001 |
| 6183694 | Spectrophotometric apparatus for reducing fluid carryover An apparatus adapted to inspect reagent strips having fluid samples, such as urine samples, disposed thereon and to reduce the likelihood of contamination of one of the fluid samples with another of the fluid samples is provided with a reagent strip suppo... | 02/06/2001 |
| 6183972 | Method for the determination of analyte concentration in a lateral flow sandwich immunoassay exhibiting high-dose hook effect Disclosed is a method for determining the concentration of an analyte in a fluid test medium by use of an immunochromatographic test strip through which the test fluid can flow by capillarity. The test strip has at least two capture bands and optionally o... | 02/06/2001 |
| 6180409 | Spectrophotometric apparatus with multiple readheads An apparatus for inspecting a reagent strip (14) having a fluid sample disposed thereon is provided with a conveyor system (80) adapted to move the reagent strip (14) from a first reagent strip inspection location to a second reagent strip inspection loca... | 01/30/2001 |
| 6180417 | Immunochromatographic assay Disclosed is a device and method for carrying out an assay for an analyte in a fluid test sample by immunochromatography. The device involves a strip having a non-porous receiving member of a hydrophobic material in direct fluid communication with a reage... | 01/30/2001 |
| 6096269 | Analyte detection device and process The present invention provides a device and a process for detecting an analyte in a biological fluid. That device comprises a cover portion with a restricted area for sample application, a separation matrix for separation of the analyte from substances in... | 08/01/2000 |
| 6074881 | Method for the prevention of hemoglobin interference in reagent systems for measuring peroxidase activity The present invention involves an improvement to an assay for the activity of a metal chelate, such as copper II/creatinine, which activity is related to the concentration of the analyte in a fluid test sample. In carrying out the assay, there is combined... | 06/13/2000 |
| 6043043 | Method for the determination of hemoglobin adducts Disclosed is an improvement to the method of determining the concentration of a hemoglobin adduct in a blood sample by the steps of assaying the blood sample for the total amount of hemoglobin, assaying the blood sample for the hemoglobin adduct, and divi... | 03/28/2000 |
| 6027570 | Cleaning method for optical surfaces of urine analyzers Disclosed is a method for cleaning optical surfaces, such as those in a urine analyzer, which surfaces come into repeated contact with urine test samples. The method involves contacting the optical surfaces with an aqueous solution of a quaternary ammoniu... | 02/22/2000 |
| 6001656 | Method for the detection of creatinine Disclosed is an improvement to the assay for creatinine in fluid test samples by contacting the test sample with a reagent formulation containing cupric ions, a hydroperoxide and an oxidizable dye. The improvement involves the inclusion of one or more sel... | 12/14/1999 |
| 5972715 | Use of thermochromic liquid crystals in reflectometry based diagnostic methods A method for improving the accuracy of temperature sensitive diagnostic assays which are carried out using reflectance spectrometers to detect color changes in a solid test system which has been contacted with a fluid test system suspected of containing a... | 10/26/1999 |
| 5945341 | System for the optical identification of coding on a diagnostic test strip Disclosed is an automated method for reading a test strip for the analysis of one or more analyte in a liquid test sample. The method involves the spectrophotometric reading of a test strip which bears at least two marker fields on its surface which are c... | 08/31/1999 |
| 5908787 | Total protein detection method Disclosed is an improved assay for the determination of total protein in an aqueous test fluid such as urine. The assay involves combining the test fluid with a molybdate or tungstate salt and a dye which forms a complex with molybdate or tungstate ion at... | 06/01/1999 |
| 5902888 | Synthesis of 6-functionalized estriol haptens and protein conjugates thereof Disclosed are 6-derivatized estriol compounds which, when conjugated to a protein, are useful in the in vivo preparation of antibodies specific to estriol. When labeled with a detectable label, the estriol derivatives are useful as haptens in a com... | 05/11/1999 |
| 5895765 | Method for the detection of an analyte by immunochromatography Disclosed is an improved method for the detection of an analyte in a fluid test sample using a strip of a negatively charged matrix material having a zone containing mobile, labeled binding partner for the analyte and a separate zone for capturing the lab... | 04/20/1999 |
| 5876944 | Method for amplification of the response signal in a sandwich immunoassay Disclosed is an improvement to a sandwich type immunoassay in which there is immobilized to a solid support an antibody which is specific to an epitope of the analyte whose presence or concentration is being sought and a first labeled antibody which is sp... | 03/02/1999 |
| 5866353 | Electro chemical biosensor containing diazacyanine mediator for co-enzyme regeneration A variety of diazacyanine mediators that are soluble in aqueous media and which do not inhibit enzymatic activity are provided for use on the surface of a working electrode of a electrochemical biosensor for electrochemical co-enzyme regeneration. The co-... | 02/02/1999 |